| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pan Meng, Yuanshan Han, Qin Yang, Hui Yang, Qing Zhu, Xiaoyuan Lin, Xiuli Zhang, Hongqing Zhao, Zhuo Liu, Jian Liu, Lin Tang, Weixu Luo, Yuhong Wan. Xiaoyao Kangai Jieyu Fang, a Chinese Herbal Formulation, Ameliorates Cancer-Related Depression Concurrent with Breast Cancer in Mice via Promoting Hippocampal Synaptic Plasticity. Evidence-based complementary and alternative medicine : eCAM. vol 2018. 2020-10-01. PMID:30581482. |
also, the pathological changes of the tumor, hippocampus, and the expressions of gr, nr2a, nr2b, camkii, creb, and bdnf were detected. |
2020-10-01 |
2023-08-13 |
mouse |
| Pan Meng, Yuanshan Han, Qin Yang, Hui Yang, Qing Zhu, Xiaoyuan Lin, Xiuli Zhang, Hongqing Zhao, Zhuo Liu, Jian Liu, Lin Tang, Weixu Luo, Yuhong Wan. Xiaoyao Kangai Jieyu Fang, a Chinese Herbal Formulation, Ameliorates Cancer-Related Depression Concurrent with Breast Cancer in Mice via Promoting Hippocampal Synaptic Plasticity. Evidence-based complementary and alternative medicine : eCAM. vol 2018. 2020-10-01. PMID:30581482. |
also, it reduced the content of cort, acth, crh, and ca125, ca153, cea in the blood, protected the pathological changes of the hippocampus and tumor, upregulated the expression of gr, creb, and bdnf in the hippocampus, and significantly decreased the expression of nr2a, nr2b, and camkii. |
2020-10-01 |
2023-08-13 |
mouse |
| Yu Zhao, Jinling Wang, Jiwei Du, Baixiang Li, Xingchun Gou, Jiannan Liu, Lichao Hou, Hanfei Sang, Bin Den. TAT-Ngn2 Enhances Cognitive Function Recovery and Regulates Caspase-Dependent and Mitochondrial Apoptotic Pathways After Experimental Stroke. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:30618628. |
furthermore, tat-ngn2 alleviated hippocampal neuronal damage and apoptosis, and inhibited the cytochrome c (cytc) leak from the mitochondria to the cytoplasm through regulating the expression levels of brain-derived neurotrophic factor (bdnf), phosphorylation tropomyosin-related kinase b (ptrkb), bcl-2, bax and cleaved caspase-3 after reperfusion injury |
2020-10-01 |
2023-08-13 |
mouse |
| Guillermo Moya-Alvarado, Andres Gonzalez, Nicolas Stuardo, Francisca C Bronfma. Brain-Derived Neurotrophic Factor (BDNF) Regulates Rab5-Positive Early Endosomes in Hippocampal Neurons to Induce Dendritic Branching. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:30618640. |
brain-derived neurotrophic factor (bdnf) regulates rab5-positive early endosomes in hippocampal neurons to induce dendritic branching. |
2020-10-01 |
2023-08-13 |
Not clear |
| Guillermo Moya-Alvarado, Andres Gonzalez, Nicolas Stuardo, Francisca C Bronfma. Brain-Derived Neurotrophic Factor (BDNF) Regulates Rab5-Positive Early Endosomes in Hippocampal Neurons to Induce Dendritic Branching. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:30618640. |
the objective of our work was to study the regulation of rab5-positive endosomes by bdnf at different levels, including dynamic, activity and protein levels in hippocampal neurons. |
2020-10-01 |
2023-08-13 |
Not clear |
| Guillermo Moya-Alvarado, Andres Gonzalez, Nicolas Stuardo, Francisca C Bronfma. Brain-Derived Neurotrophic Factor (BDNF) Regulates Rab5-Positive Early Endosomes in Hippocampal Neurons to Induce Dendritic Branching. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:30618640. |
long-term treatment of hippocampal neurons with bdnf increased the protein levels of rab5 and rab11 in an mtor-dependent manner. |
2020-10-01 |
2023-08-13 |
Not clear |
| Juliane Zemdegs, Quentin Rainer, Cindy P Grossmann, Delphine Rousseau-Ralliard, Alain Grynberg, Eliane Ribeiro, Bruno P Guiar. Anxiolytic- and Antidepressant-Like Effects of Fish Oil-Enriched Diet in Brain-Derived Neurotrophic Factor Deficient Mice. Frontiers in neuroscience. vol 12. 2020-10-01. PMID:30622454. |
in contrast, low bdnf levels and hippocampal atrophy were observed in animal models of depression. |
2020-10-01 |
2023-08-13 |
mouse |
| Wen-Bo Zhou, Zong-Ning Miao, Bin Zhang, Wei Long, Fang-Xiu Zheng, Jing Kong, Bin Y. Luteolin induces hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome. Neural regeneration research. vol 14. issue 4. 2020-10-01. PMID:30632501. |
western blot assay was used to analyze the protein levels of brain-derived neurotrophic factor (bdnf) and phospho-extracellular signal-regulated kinase 1/2 (p-erk1/2) in the hippocampus. |
2020-10-01 |
2023-08-13 |
mouse |
| Mengmeng You, Yongming Pan, Yichen Liu, Yifan Chen, Yuqi Wu, Juanjuan Si, Kai Wang, Fuliang H. Royal Jelly Alleviates Cognitive Deficits and β-Amyloid Accumulation in APP/PS1 Mouse Model Via Activation of the cAMP/PKA/CREB/BDNF Pathway and Inhibition of Neuronal Apoptosis. Frontiers in aging neuroscience. vol 10. 2020-10-01. PMID:30687079. |
importantly, hippocampal cyclic adenosine monophosphate (camp), p-pka, p-creb and bdnf levels were significantly increased in the app/ps1 mice after rj treatment, indicating that the camp/pka/creb/bdnf pathway might be related to the ameliorative effect of rj on cognitive decline. |
2020-10-01 |
2023-08-13 |
mouse |
| Michael Zhang, Kennett D Radford, Mercedes Driscoll, Salsabila Purnomo, Jean Kim, Kwang H Cho. Effects of subanesthetic intravenous ketamine infusion on neuroplasticity-related proteins in the prefrontal cortex, amygdala, and hippocampus of Sprague-Dawley rats. IBRO reports. vol 6. 2020-10-01. PMID:30723838. |
the 10 mg/kg ketamine infusion increased bdnf levels in the amygdala, but decreased perk levels in the mpfc and hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Emanuela Paldino, Carmela Giampà, Elena Montagna, Cecilia Angeloni, Francesca R Fusc. Modulation of Phospho-CREB by Systemically Administered Recombinant BDNF in the Hippocampus of the R6/2 Mouse Model of Huntington's Disease. Neuroscience journal. vol 2019. 2020-10-01. PMID:30881980. |
modulation of phospho-creb by systemically administered recombinant bdnf in the hippocampus of the r6/2 mouse model of huntington's disease. |
2020-10-01 |
2023-08-13 |
mouse |
| Neus Gomila Pelegri, Catherine A Gorrie, Jerran Santo. Rat Hippocampal Neural Stem Cell Modulation Using PDGF, VEGF, PDGF/VEGF, and BDNF. Stem cells international. vol 2019. 2020-10-01. PMID:31011333. |
rat hippocampal neural stem cell modulation using pdgf, vegf, pdgf/vegf, and bdnf. |
2020-10-01 |
2023-08-13 |
rat |
| Ana Paula De Vincenti, Antonella S Ríos, Gustavo Paratcha, Fernanda Ledd. Mechanisms That Modulate and Diversify BDNF Functions: Implications for Hippocampal Synaptic Plasticity. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31024262. |
mechanisms that modulate and diversify bdnf functions: implications for hippocampal synaptic plasticity. |
2020-10-01 |
2023-08-13 |
Not clear |
| Ana Paula De Vincenti, Antonella S Ríos, Gustavo Paratcha, Fernanda Ledd. Mechanisms That Modulate and Diversify BDNF Functions: Implications for Hippocampal Synaptic Plasticity. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31024262. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin that has pleiotropic effects on neuronal morphology and synaptic plasticity that underlie hippocampal circuit development and cognition. |
2020-10-01 |
2023-08-13 |
Not clear |
| Bruk Getachew, Yousef Tizab. Both Ketamine and NBQX Attenuate Alcohol-Withdrawal Induced Depression in Male Rats. Journal of drug and alcohol research. vol 8. 2020-10-01. PMID:31032138. |
the animals were sacrificed 2 h later for evaluation of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Bruk Getachew, Yousef Tizab. Both Ketamine and NBQX Attenuate Alcohol-Withdrawal Induced Depression in Male Rats. Journal of drug and alcohol research. vol 8. 2020-10-01. PMID:31032138. |
parallel to these behavioral observations, both ketamine and nbqx normalized the reduction in hippocampal bdnf caused by alcohol withdrawal. |
2020-10-01 |
2023-08-13 |
rat |
| Bruk Getachew, Yousef Tizab. Both Ketamine and NBQX Attenuate Alcohol-Withdrawal Induced Depression in Male Rats. Journal of drug and alcohol research. vol 8. 2020-10-01. PMID:31032138. |
these results suggest that either nmda or ampa/kainate receptor antagonists, acting at least partially through hippocampal bdnf, may be of therapeutic potential in alcohol use disorder. |
2020-10-01 |
2023-08-13 |
rat |
| Huaiqing Luo, Yang Xiang, Xiangping Qu, Huijun Liu, Chi Liu, Guangyi Li, Li Han, Xiaoqun Qi. Apelin-13 Suppresses Neuroinflammation Against Cognitive Deficit in a Streptozotocin-Induced Rat Model of Alzheimer's Disease Through Activation of BDNF-TrkB Signaling Pathway. Frontiers in pharmacology. vol 10. 2020-10-01. PMID:31040784. |
protein expression of apelin, apj, microglial marker (iba1), astroglia marker (gfap), interleukin 1 beta (il-1β), tumor necrosis factor-α (tnf-α), synaptophysin (syp), brain-derived neurotrophic factor (bdnf), trkb, phospho-trkb (p-trkb) in the hippocampus were examined by western blotting or immunohistochemistry. |
2020-10-01 |
2023-08-13 |
rat |
| Nicholas Chaaya, Angela Jacques, Arnauld Belmer, Kate Beecher, Syed A Ali, Fatemeh Chehrehasa, Andrew R Battle, Luke R Johnson, Selena E Bartlet. Contextual Fear Conditioning Alter Microglia Number and Morphology in the Rat Dorsal Hippocampus. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31139053. |
the current study was designed to evaluate how two different contextual fear memories alter amygdala and hippocampus microglia, brain derived neurotrophic factor (bdnf), and phosphorylated cyclic-amp response element binding (pcreb). |
2020-10-01 |
2023-08-13 |
rat |
| Nicholas Chaaya, Angela Jacques, Arnauld Belmer, Kate Beecher, Syed A Ali, Fatemeh Chehrehasa, Andrew R Battle, Luke R Johnson, Selena E Bartlet. Contextual Fear Conditioning Alter Microglia Number and Morphology in the Rat Dorsal Hippocampus. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31139053. |
the unpaired fear conditioning procedure (whereby non-reinforced and non-overlapping auditory tones were provided at random intervals during conditioning), despite producing equivalent levels of fear as the standard procedure, did not alter microglia, bdnf or pcreb number in any dorsal hippocampus or lateral amygdala brain regions. |
2020-10-01 |
2023-08-13 |
rat |