| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ana Paula De Vincenti, Antonella S Ríos, Gustavo Paratcha, Fernanda Ledd. Mechanisms That Modulate and Diversify BDNF Functions: Implications for Hippocampal Synaptic Plasticity. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31024262. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin that has pleiotropic effects on neuronal morphology and synaptic plasticity that underlie hippocampal circuit development and cognition. |
2020-10-01 |
2023-08-13 |
Not clear |
| Bruk Getachew, Yousef Tizab. Both Ketamine and NBQX Attenuate Alcohol-Withdrawal Induced Depression in Male Rats. Journal of drug and alcohol research. vol 8. 2020-10-01. PMID:31032138. |
the animals were sacrificed 2 h later for evaluation of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Bruk Getachew, Yousef Tizab. Both Ketamine and NBQX Attenuate Alcohol-Withdrawal Induced Depression in Male Rats. Journal of drug and alcohol research. vol 8. 2020-10-01. PMID:31032138. |
parallel to these behavioral observations, both ketamine and nbqx normalized the reduction in hippocampal bdnf caused by alcohol withdrawal. |
2020-10-01 |
2023-08-13 |
rat |
| Bruk Getachew, Yousef Tizab. Both Ketamine and NBQX Attenuate Alcohol-Withdrawal Induced Depression in Male Rats. Journal of drug and alcohol research. vol 8. 2020-10-01. PMID:31032138. |
these results suggest that either nmda or ampa/kainate receptor antagonists, acting at least partially through hippocampal bdnf, may be of therapeutic potential in alcohol use disorder. |
2020-10-01 |
2023-08-13 |
rat |
| Huaiqing Luo, Yang Xiang, Xiangping Qu, Huijun Liu, Chi Liu, Guangyi Li, Li Han, Xiaoqun Qi. Apelin-13 Suppresses Neuroinflammation Against Cognitive Deficit in a Streptozotocin-Induced Rat Model of Alzheimer's Disease Through Activation of BDNF-TrkB Signaling Pathway. Frontiers in pharmacology. vol 10. 2020-10-01. PMID:31040784. |
protein expression of apelin, apj, microglial marker (iba1), astroglia marker (gfap), interleukin 1 beta (il-1β), tumor necrosis factor-α (tnf-α), synaptophysin (syp), brain-derived neurotrophic factor (bdnf), trkb, phospho-trkb (p-trkb) in the hippocampus were examined by western blotting or immunohistochemistry. |
2020-10-01 |
2023-08-13 |
rat |
| Nicholas Chaaya, Angela Jacques, Arnauld Belmer, Kate Beecher, Syed A Ali, Fatemeh Chehrehasa, Andrew R Battle, Luke R Johnson, Selena E Bartlet. Contextual Fear Conditioning Alter Microglia Number and Morphology in the Rat Dorsal Hippocampus. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31139053. |
the current study was designed to evaluate how two different contextual fear memories alter amygdala and hippocampus microglia, brain derived neurotrophic factor (bdnf), and phosphorylated cyclic-amp response element binding (pcreb). |
2020-10-01 |
2023-08-13 |
rat |
| Nicholas Chaaya, Angela Jacques, Arnauld Belmer, Kate Beecher, Syed A Ali, Fatemeh Chehrehasa, Andrew R Battle, Luke R Johnson, Selena E Bartlet. Contextual Fear Conditioning Alter Microglia Number and Morphology in the Rat Dorsal Hippocampus. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31139053. |
the unpaired fear conditioning procedure (whereby non-reinforced and non-overlapping auditory tones were provided at random intervals during conditioning), despite producing equivalent levels of fear as the standard procedure, did not alter microglia, bdnf or pcreb number in any dorsal hippocampus or lateral amygdala brain regions. |
2020-10-01 |
2023-08-13 |
rat |
| Jing Yang, Rongjun Liu, Fan Lu, Fang Xu, Jinwei Zheng, Zhao Li, Wei Cui, Chuang Wang, Junfang Zhang, Shujun Xu, Wenhua Zhou, Qinwen Wang, Junping Chen, Xiaowei Che. Fast Green FCF Attenuates Lipopolysaccharide-Induced Depressive-Like Behavior and Downregulates TLR4/Myd88/NF-κB Signal Pathway in the Mouse Hippocampus. Frontiers in pharmacology. vol 10. 2020-10-01. PMID:31139084. |
fast green fcf also downregulated hippocampal tumor necrosis factor (tnf)-α, interleukin (il)-1β, and il-6, but did not alter the level of the brain-derived neurotrophic factor (bdnf) in the hippocampus of lps-treated mice. |
2020-10-01 |
2023-08-13 |
mouse |
| Zülal Kaptan, Kadriye Akgün Dar, Ayşegül Kapucu, Huri Bulut, Gülay Üzü. Effect of enriched environment and predictable chronic stress on spatial memory in adolescent rats: Predominant expression of BDNF, nNOS, and interestingly malondialdehyde in the right hippocampus. Brain research. vol 1721. 2020-10-01. PMID:31299186. |
effect of enriched environment and predictable chronic stress on spatial memory in adolescent rats: predominant expression of bdnf, nnos, and interestingly malondialdehyde in the right hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Zülal Kaptan, Kadriye Akgün Dar, Ayşegül Kapucu, Huri Bulut, Gülay Üzü. Effect of enriched environment and predictable chronic stress on spatial memory in adolescent rats: Predominant expression of BDNF, nNOS, and interestingly malondialdehyde in the right hippocampus. Brain research. vol 1721. 2020-10-01. PMID:31299186. |
the levels of brain-derived neurotrophic factor (bdnf) and neuronal nitric oxide synthase (nnos), which are critical for synaptic plasticity; malondialdehyde (mda; lipid-peroxidation indicator); protein carbonyl (protein-oxidation indicator); and superoxide dismutase (antioxidant enzyme) were evaluated in the left and right hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Zülal Kaptan, Kadriye Akgün Dar, Ayşegül Kapucu, Huri Bulut, Gülay Üzü. Effect of enriched environment and predictable chronic stress on spatial memory in adolescent rats: Predominant expression of BDNF, nNOS, and interestingly malondialdehyde in the right hippocampus. Brain research. vol 1721. 2020-10-01. PMID:31299186. |
in both the pcs and ee groups, spatial memory improved and bdnf was increased in both halves of the hippocampus, still there was an asymmetry. |
2020-10-01 |
2023-08-13 |
rat |
| Zülal Kaptan, Kadriye Akgün Dar, Ayşegül Kapucu, Huri Bulut, Gülay Üzü. Effect of enriched environment and predictable chronic stress on spatial memory in adolescent rats: Predominant expression of BDNF, nNOS, and interestingly malondialdehyde in the right hippocampus. Brain research. vol 1721. 2020-10-01. PMID:31299186. |
our results suggest that both pcs and ee improved spatial memory by increasing bdnf and nnos in the right hippocampus and that, interestingly; mda could be the physiological signal molecule in the right hippocampus for spatial memory process. |
2020-10-01 |
2023-08-13 |
rat |
| Wenjuan Yu, Min Zhu, Hongwei Fang, Jie Zhou, Le Ye, Wenyu Bian, Yuan Wang, Hui Zhu, Jie Xiao, Hao Zhu, Huafang L. Risperidone Reverses the Downregulation of BDNF in Hippocampal Neurons and MK801-Induced Cognitive Impairment in Rats. Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:31396062. |
risperidone reverses the downregulation of bdnf in hippocampal neurons and mk801-induced cognitive impairment in rats. |
2020-10-01 |
2023-08-13 |
rat |
| Wenjuan Yu, Min Zhu, Hongwei Fang, Jie Zhou, Le Ye, Wenyu Bian, Yuan Wang, Hui Zhu, Jie Xiao, Hao Zhu, Huafang L. Risperidone Reverses the Downregulation of BDNF in Hippocampal Neurons and MK801-Induced Cognitive Impairment in Rats. Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:31396062. |
our previous study showed that brain-derived neurotrophic factor (bdnf) signaling was upregulated in cultured hippocampal astrocytes in response to mk-801. |
2020-10-01 |
2023-08-13 |
rat |
| Wenjuan Yu, Min Zhu, Hongwei Fang, Jie Zhou, Le Ye, Wenyu Bian, Yuan Wang, Hui Zhu, Jie Xiao, Hao Zhu, Huafang L. Risperidone Reverses the Downregulation of BDNF in Hippocampal Neurons and MK801-Induced Cognitive Impairment in Rats. Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:31396062. |
to address this issue, we examined bdnf expression in the hippocampus of rats that received repeated injections of mk-801 (0.5 mg/kg body weight for 6 days) and in primary cultured hippocampal neurons incubated with 20 μm mk-801 for 24 h. bdnf expression and cognitive function were also evaluated in rats receiving intraperitoneal injections of risperidone (1 mg/kg body weight) once daily for 7 days and in hippocampal neurons incubated with 10 μm risperidone following mk801 treatment. |
2020-10-01 |
2023-08-13 |
rat |
| Wenjuan Yu, Min Zhu, Hongwei Fang, Jie Zhou, Le Ye, Wenyu Bian, Yuan Wang, Hui Zhu, Jie Xiao, Hao Zhu, Huafang L. Risperidone Reverses the Downregulation of BDNF in Hippocampal Neurons and MK801-Induced Cognitive Impairment in Rats. Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:31396062. |
mk-801 treatment decreased bdnf expression in the rat hippocampus as well as the expression and secretion of bdnf in hippocampal neurons |
2020-10-01 |
2023-08-13 |
rat |
| Rhiannon Jones, Gavin Craig, Joydeep Bhattachary. Brain-Derived Neurotrophic Factor Val66Met Polymorphism Is Associated With a Reduced ERP Component Indexing Emotional Recollection. Frontiers in psychology. vol 10. 2020-10-01. PMID:31496979. |
the met allele of the brain-derived neurotrophic factor (bdnf) val66met polymorphism is associated with reduced functioning of the amygdala and hippocampus. |
2020-10-01 |
2023-08-13 |
Not clear |
| Sarah Mahboubi, Mohammad Nasehi, Alireza Imani, Mitra-Sadat Sadat-Shirazi, Mohammad-Reza Zarrindast, Nasim Vousooghi, Maryam Noroozia. Benefit effect of REM-sleep deprivation on memory impairment induced by intensive exercise in male wistar rats: with respect to hippocampal BDNF and TrkB. Nature and science of sleep. vol 11. 2020-10-01. PMID:31576186. |
benefit effect of rem-sleep deprivation on memory impairment induced by intensive exercise in male wistar rats: with respect to hippocampal bdnf and trkb. |
2020-10-01 |
2023-08-13 |
rat |
| Farimah Beheshti, Mahmoud Hosseini, Milad Hashemzehi, Mohammad Soukhtanloo, Majid Khazaei, Mohammad Naser Shafe. The effects of PPAR-γ agonist pioglitazone on hippocampal cytokines, brain-derived neurotrophic factor, memory impairment, and oxidative stress status in lipopolysaccharide-treated rats. Iranian journal of basic medical sciences. vol 22. issue 8. 2020-10-01. PMID:31579451. |
the aim of current study was to evaluate improving effects of pioglitazone as an agonist of peroxisome proliferator-activated receptor gamma (pparγ), on brain-derived neurotrophic factor (bdnf) and cytokines as well as tissue oxidative damage criteria in the hippocampus in a rat model of lipopolysaccharide (lps) induced memory impairment. |
2020-10-01 |
2023-08-13 |
rat |
| Kandaswamy Selvakumar, Senthamilselvan Bavithra, Gunasekaran Krishnamoorthy, Jagadeesan Arunakara. Impact of quercetin on tight junctional proteins and BDNF signaling molecules in hippocampus of PCBs-exposed rats. Interdisciplinary toxicology. vol 11. issue 4. 2020-10-01. PMID:31762681. |
impact of quercetin on tight junctional proteins and bdnf signaling molecules in hippocampus of pcbs-exposed rats. |
2020-10-01 |
2023-08-13 |
rat |