| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sydney Corey, Diego Incontri Abraham, Yuji Kaneko, Jea-Young Lee, Cesar V Borlonga. Selective endovascular cooling for stroke entails brain-derived neurotrophic factor and splenic IL-10 modulation. Brain research. vol 1722. 2020-10-21. PMID:31415765. |
animals that received sec prior to stroke displayed elevated brain bdnf expression ipsilaterally and contralaterally across the cortex, striatum, and hippocampus. |
2020-10-21 |
2023-08-13 |
rat |
| Xiaole Tang, Yilin Zhao, Zhiqiang Zhou, Jing Yan, Biyun Zhou, Xiaohui Chi, Ailin Luo, Shiyong L. Resveratrol Mitigates Sevoflurane-Induced Neurotoxicity by the SIRT1-Dependent Regulation of BDNF Expression in Developing Mice. Oxidative medicine and cellular longevity. vol 2020. 2020-10-19. PMID:32148659. |
pretreatment of neonatal mice with resveratrol nearly reversed the reduction in hippocampal sirt1 expression, which increased the expression of bdnf in developing mice exposed to sevoflurane. |
2020-10-19 |
2023-08-13 |
mouse |
| Yuting Song, Xiuxiu Li, Xiangdan Gong, Xin Zhao, Zhengliang Ma, Tianjiao Xia, Xiaoping G. Green tea polyphenols improve isoflurane-induced cognitive impairment via modulating oxidative stress. The Journal of nutritional biochemistry. vol 73. 2020-10-16. PMID:31704346. |
protein expression levels of right hippocampus p-camkii, p-creb and bdnf were examined by western blot. |
2020-10-16 |
2023-08-13 |
mouse |
| Maria Grazia Piancino, Alessandro Tortarolo, Antonella Polimeni, Ennio Bramanti, Placido Bramant. Altered mastication adversely impacts morpho-functional features of the hippocampus: A systematic review on animal studies in three different experimental conditions involving the masticatory function. PloS one. vol 15. issue 8. 2020-10-15. PMID:32817680. |
the literature reviewed agrees that a disturbed mastication is significantly associated with a reduced number of hippocampal pyramidal neurons in cornu ammonis (ca)1 and ca3, downregulation of brain derived neurotrophic factor (bdnf), reduced synaptic activity, reduced neurogenesis in the dentate gyrus (dg), glial proliferation, and reduced performances in behavioural tests, indicating memory impairment and reduced spatial orientation. |
2020-10-15 |
2023-08-13 |
Not clear |
| Yingrak Boondam, Phanit Songvut, Mayuree H Tantisira, Sompol Tapechum, Kanokwan Tilokskulchai, Narawut Pakapro. Inverted U-shaped response of a standardized extract of Centella asiatica (ECa 233) on memory enhancement. Scientific reports. vol 9. issue 1. 2020-10-14. PMID:31182820. |
plasticity-related protein expressions (nr2a, nr2b, psd-95, bdnf and trkb) in hippocampus was also measured. |
2020-10-14 |
2023-08-13 |
rat |
| Jianguo Li, Deping Yan, Na Ma, Jing Chen, Xin Zhao, Yu Zhang, Ce Zhan. Transient Forebrain Ischemia Induces Differential Bdnf Transcript Expression and Histone Acetylation Patterns in the Rat Hippocampus. Journal of molecular neuroscience : MN. vol 70. issue 4. 2020-10-08. PMID:31828524. |
transient forebrain ischemia induces differential bdnf transcript expression and histone acetylation patterns in the rat hippocampus. |
2020-10-08 |
2023-08-13 |
rat |
| Jianguo Li, Deping Yan, Na Ma, Jing Chen, Xin Zhao, Yu Zhang, Ce Zhan. Transient Forebrain Ischemia Induces Differential Bdnf Transcript Expression and Histone Acetylation Patterns in the Rat Hippocampus. Journal of molecular neuroscience : MN. vol 70. issue 4. 2020-10-08. PMID:31828524. |
however, the exact mechanism of bdnf expression in the hippocampus after ischemia is unclear. |
2020-10-08 |
2023-08-13 |
rat |
| Tie-Yuan Zhang, Dara Shahrokh, Ian C Hellstrom, Xianglan Wen, Josie Diorio, Lionel Breuillaud, Christian Caldji, Michael J Meane. Brain-Derived Neurotrophic Factor in the Nucleus Accumbens Mediates Individual Differences in Behavioral Responses to a Natural, Social Reward. Molecular neurobiology. vol 57. issue 1. 2020-10-07. PMID:31327126. |
we found that bdnf gene expression is increased in the hippocampus of rat mothers that show increased pup licking/grooming (high lg mothers) compared to low lg mothers. |
2020-10-07 |
2023-08-13 |
rat |
| Tie-Yuan Zhang, Dara Shahrokh, Ian C Hellstrom, Xianglan Wen, Josie Diorio, Lionel Breuillaud, Christian Caldji, Michael J Meane. Brain-Derived Neurotrophic Factor in the Nucleus Accumbens Mediates Individual Differences in Behavioral Responses to a Natural, Social Reward. Molecular neurobiology. vol 57. issue 1. 2020-10-07. PMID:31327126. |
oxytocin antagonist significantly prevented the oxytocin-induced bdnf gene expression in primary hippocampal cell cultures. |
2020-10-07 |
2023-08-13 |
rat |
| Yushan Jiang, Ying Liu, Mingqing Gao, Meilan Xue, Zilong Wang, Hui Lian. Nicotinamide riboside alleviates alcohol-induced depression-like behaviours in C57BL/6J mice by altering the intestinal microbiota associated with microglial activation and BDNF expression. Food & function. vol 11. issue 1. 2020-10-07. PMID:31820774. |
furthermore, nr significantly upregulated bdnf and diminished the inhibition of the akt/gsk3β/β-catenin signalling pathway in the hippocampus of these mice. |
2020-10-07 |
2023-08-13 |
mouse |
| Kanzo Suzuki, Lisa M Monteggi. The role of eEF2 kinase in the rapid antidepressant actions of ketamine. Advances in pharmacology (San Diego, Calif.). vol 89. 2020-10-07. PMID:32616215. |
our studies show ketamine blocks synaptic nmda receptors involved in spontaneous synaptic transmission, which deactivates calcium/calmodulin-dependent kinase eukaryotic elongation factor 2 kinase (eef2k), resulting in dephosphorylation of eukaryotic elongation factor 2 (eef2), and the subsequent desuppression of brain-derived neurotrophic factor (bdnf) protein synthesis in the hippocampus. |
2020-10-07 |
2023-08-13 |
Not clear |
| Jie Lv, Wei Ou, Xiao-Hua Zou, Yin Yao, Jin-Li W. Effect of dexmedetomidine on hippocampal neuron development and BDNF-TrkB signal expression in neonatal rats. Neuropsychiatric disease and treatment. vol 12. 2020-10-01. PMID:28003751. |
the study aimed to explore the effect of dexmedetomidine (dex) on hippocampal neuron development process and on molecular expression of brain-derived neurotrophic factor (bdnf)-tyrosine receptor kinase b (trkb) signaling pathway in neonatal rats. |
2020-10-01 |
2023-08-13 |
rat |
| Somoday Hazra, Sourav Kumar, Goutam Kumar Saha, Amal Chandra Monda. Reversion of BDNF, Akt and CREB in Hippocampus of Chronic Unpredictable Stress Induced Rats: Effects of Phytochemical, Psychiatry investigation. vol 14. issue 1. 2020-10-01. PMID:28096878. |
reversion of bdnf, akt and creb in hippocampus of chronic unpredictable stress induced rats: effects of phytochemical, the aims of the present study were to explore the behavioural effects and to understand the possible mode of action of bacopa monnieri extract (bme) on chronic unpredictable stress (cus) induced depressive model and the biochemical alterations such as brain derived neurotrophic factor (bdnf), akt, cyclic-amp response element binding (creb) protein level in the hippocampus of rats. |
2020-10-01 |
2023-08-13 |
rat |
| Ericksen Mielle Borba, Juliana Avila Duarte, Giovana Bristot, Ellen Scotton, Ana Luiza Camozzato, Márcia Lorena Fagundes Chave. Brain-Derived Neurotrophic Factor Serum Levels and Hippocampal Volume in Mild Cognitive Impairment and Dementia due to Alzheimer Disease. Dementia and geriatric cognitive disorders extra. vol 6. issue 3. 2020-10-01. PMID:28101102. |
we aimed to evaluate bdnf serum levels and hippocampal volume in clinical ad (dementia and mild cognitive impairment [mci]). |
2020-10-01 |
2023-08-13 |
Not clear |
| Guangdong Chen, Xiaodong Lin, Gongying Li, Diego Jiang, Zhiruo Lib, Ronghuan Jiang, Chuanjun Zhu. Risperidone reverses the spatial object recognition impairment and hippocampal BDNF-TrkB signalling system alterations induced by acute MK-801 treatment. Biomedical reports. vol 6. issue 3. 2020-10-01. PMID:28451387. |
the aim of the present study was to investigate the effects of a commonly-used atypical antipsychotic, risperidone, on alterations in spatial learning and in the hippocampal brain-derived neurotrophic factor (bdnf)-tyrosine receptor kinase b (trkb) signalling system caused by acute dizocilpine maleate (mk-801) treatment. |
2020-10-01 |
2023-08-13 |
rat |
| Guangdong Chen, Xiaodong Lin, Gongying Li, Diego Jiang, Zhiruo Lib, Ronghuan Jiang, Chuanjun Zhu. Risperidone reverses the spatial object recognition impairment and hippocampal BDNF-TrkB signalling system alterations induced by acute MK-801 treatment. Biomedical reports. vol 6. issue 3. 2020-10-01. PMID:28451387. |
in experiment 1, adult male sprague-dawley rats subjected to acute treatment of either low-dose mk801 (0.1 mg/kg) or normal saline (vehicle) were tested for spatial object recognition and hippocampal expression levels of bdnf, trkb and the phophorylation of trkb (p-trkb). |
2020-10-01 |
2023-08-13 |
rat |
| Ling-Sha Ju, Jiao-Jiao Yang, Lei Lei, Jiang-Yan Xia, Dan Luo, Mu-Huo Ji, Anatoly E Martynyuk, Jian-Jun Yan. The Combination of Long-term Ketamine and Extinction Training Contributes to Fear Erasure by Bdnf Methylation. Frontiers in cellular neuroscience. vol 11. 2020-10-01. PMID:28473755. |
mice, subjected to ifs, exhibited anxiety-like behavior and fear relapse, accompanied by the increased levels of dna methyltransferases, hyper-methylation of bdnf gene, and decreased bdnf mrna expression in the medial prefrontal cortex (mpfc) and hippocampus (hip). |
2020-10-01 |
2023-08-13 |
mouse |
| b' Jana Mur\\xc3\\xadnov\\xc3\\xa1, Nata\\xc5\\xa1a Hlav\\xc3\\xa1\\xc4\\x8dov\\xc3\\xa1, Magdal\\xc3\\xa9na Chmelov\\xc3\\xa1, Igor Rie\\xc4\\x8dansk\\xc3\\xb. The Evidence for Altered BDNF Expression in the Brain of Rats Reared or Housed in Social Isolation: A Systematic Review. Frontiers in behavioral neuroscience. vol 11. 2020-10-01. PMID:28620285.' |
across all age groups (post-weaning, adolescent, adult), majority of the identified studies (16/21) reported a decreased expression of bdnf in the hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Yi-Lu Ye, Kai Zhong, Dan-Dan Liu, Jing Xu, Bei-Bei Pan, Xiang Li, Yue-Ping Yu, Qi Zhan. Huanglian-Jie-Du-Tang Extract Ameliorates Depression-Like Behaviors through BDNF-TrkB-CREB Pathway in Rats with Chronic Unpredictable Stress. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-10-01. PMID:28694833. |
western-blotting analysis displayed hjdt upregulated bdnf, trkb, and pcreb/creb expression in hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Fernanda E Valiati, Mailton Vasconcelos, Martina Lichtenfels, Fernanda S Petry, Rosa M M de Almeida, Gilberto Schwartsmann, Nadja Schröder, Caroline B de Farias, Rafael Roesle. Administration of a Histone Deacetylase Inhibitor into the Basolateral Amygdala Enhances Memory Consolidation, Delays Extinction, and Increases Hippocampal BDNF Levels. Frontiers in pharmacology. vol 8. 2020-10-01. PMID:28701956. |
administration of a histone deacetylase inhibitor into the basolateral amygdala enhances memory consolidation, delays extinction, and increases hippocampal bdnf levels. |
2020-10-01 |
2023-08-13 |
rat |