| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hsin-Yi Hsieh, Yu-Chieh Chen, Mei-Hsin Hsu, Hong-Ren Yu, Chung-Hao Su, You-Lin Tain, Li-Tung Huang, Jiunn-Ming Shee. Maternal Iron Deficiency Programs Offspring Cognition and Its Relationship with Gastrointestinal Microbiota and Metabolites. International journal of environmental research and public health. vol 17. issue 17. 2020-12-09. PMID:32825437. |
we used a sprague-dawley rat model of a maternal low-iron diet to explore the changes in cognition, dorsal hippocampal brain-derived neurotrophic factor (bdnf) and related pathways, gut microbiota, and related metabolites in adult male offspring. |
2020-12-09 |
2023-08-13 |
rat |
| Juliana C S Chaves, Felippe T Machado, Michael F Almeida, Tatiana B Bacovsky, Merari F R Ferrar. microRNAs expression correlates with levels of APP, DYRK1A, hyperphosphorylated Tau and BDNF in the hippocampus of a mouse model for Down syndrome during ageing. Neuroscience letters. vol 714. 2020-12-07. PMID:31605772. |
micrornas expression correlates with levels of app, dyrk1a, hyperphosphorylated tau and bdnf in the hippocampus of a mouse model for down syndrome during ageing. |
2020-12-07 |
2023-08-13 |
mouse |
| Juliana C S Chaves, Felippe T Machado, Michael F Almeida, Tatiana B Bacovsky, Merari F R Ferrar. microRNAs expression correlates with levels of APP, DYRK1A, hyperphosphorylated Tau and BDNF in the hippocampus of a mouse model for Down syndrome during ageing. Neuroscience letters. vol 714. 2020-12-07. PMID:31605772. |
in this study, we investigated the association among mirnas mir-17, -20a, -101, -106b, -199b, -26a, 26b and some of their target mrnas such as app, dyrk1a and bdnf, as well as the levels of hyperphosphorylated tau in the hippocampus of a 2 and 5 months old mice model of trisomy 21 (ts65dn). |
2020-12-07 |
2023-08-13 |
mouse |
| Jariya Umka Welbat, Salinee Naewla, Wanassanan Pannangrong, Apiwat Sirichoat, Anusara Aranarochana, Peter Wigmor. Neuroprotective effects of hesperidin against methotrexate-induced changes in neurogenesis and oxidative stress in the adult rat. Biochemical pharmacology. vol 178. 2020-12-07. PMID:32522593. |
treatment with mtx also increased malondialdehyde (mda) in both the hippocampus and prefrontal cortex and decreased levels of brain-derived neurotropic factor (bdnf) and nuclear factor erythroid 2-related factor 2 (nrf2) in the hippocampus and prefrontal cortex. |
2020-12-07 |
2023-08-13 |
rat |
| Zuntao Wu, Lin Bai, Runqi Tu, Lijie Zhang, Yue Ba, Huizhen Zhang, Xing Li, Xuemin Cheng, Wenjie Li, Hui Huan. Disruption of synaptic expression pattern and age-related DNA oxidation in a neuronal model of lead-induced toxicity. Environmental toxicology and pharmacology. vol 76. 2020-12-04. PMID:32058320. |
in the hippocampus of lead exposed mice at three age nodes, the expression of brain-derived neurotrophic factor precursor (probdnf) increased, while that of mature bdnf (mbdnf), camp-response element binding protein (creb) and phosphorylated creb (pcreb) decreased compared with the control group. |
2020-12-04 |
2023-08-13 |
mouse |
| Brittany E Dong, Hao Chen, Kazuko Sakat. BDNF deficiency and enriched environment treatment affect neurotransmitter gene expression differently across ages. Journal of neurochemistry. vol 154. issue 1. 2020-12-04. PMID:32222968. |
high-throughput quantitative reverse transcription polymerase chain reaction measured expression of 81 genes for dopamine, adrenaline, serotonin, gamma aminobutyric acid, glutamate, acetylcholine, and bdnf systems in the frontal cortex (fc) and hippocampus. |
2020-12-04 |
2023-08-13 |
mouse |
| Zhen Jin, Kyung Eun Kim, Hyun Joo Shin, Eun Ae Jeong, Kyung-Ah Park, Jong Youl Lee, Hyeong Seok An, Eun Bee Choi, Jae Hun Jeong, Woori Kwak, Gu Seob Ro. Hippocampal Lipocalin 2 Is Associated With Neuroinflammation and Iron-Related Oxidative Stress in ob/ob Mice. Journal of neuropathology and experimental neurology. vol 79. issue 5. 2020-12-04. PMID:32296847. |
using rna-seq analysis, we found that neurodegeneration- sortilin-related receptor 1 (sorl1) and brain-derived neurotrophic factor (bdnf) genes were significantly reduced in the hippocampus of ob/ob mice. |
2020-12-04 |
2023-08-13 |
mouse |
| Ivani Credidio Trombetta, José Roberto DeMoura, Cleber Rene Alves, Renato Carbonari-Brito, Felipe Xerez Cepeda, José Ribeiro Lemo. Serum Levels of BDNF in Cardiovascular Protection and in Response to Exercise. Arquivos brasileiros de cardiologia. vol 115. issue 2. 2020-12-04. PMID:32876194. |
bdnf is a neurotrophin found at high concentrations in the hippocampus and cerebral cortex and is considered a key molecule for the maintenance of synaptic plasticity and survival of neuronal cells. |
2020-12-04 |
2023-08-13 |
Not clear |
| Ning Jiang, Haixia Wang, Jingwei Lv, Qiong Wang, Cong Lu, Yujiao Li, Xinmin Li. Dammarane sapogenins attenuates stress-induced anxiety-like behaviors by upregulating ERK/CREB/BDNF pathways. Phytotherapy research : PTR. vol 34. issue 10. 2020-11-30. PMID:32431006. |
treatment with ds significantly upregulated bdnf (brain-derived neurotrophic factor), p-creb/creb and p-erk1/2/erk1/2 protein expression in the hippocampus and prefrontal cortex of csds mice. |
2020-11-30 |
2023-08-13 |
mouse |
| Natalia Dos Santos Tramontin, Sabrina da Silva, Rychard Arruda, Kellen Simon Ugioni, Paula Bortuluzzi Canteiro, Gustavo de Bem Silveira, Carolini Mendes, Paulo Cesar Lock Silveira, Alexandre Pastoris Mulle. Gold Nanoparticles Treatment Reverses Brain Damage in Alzheimer's Disease Model. Molecular neurobiology. vol 57. issue 2. 2020-11-25. PMID:31612296. |
neurotrophic factors (bdnf and ngf- β) in the cortex and hippocampus were decreased by oa. |
2020-11-25 |
2023-08-13 |
rat |
| Federico José Barreda Tomás, Paul Turko, Heike Heilmann, Thorsten Trimbuch, Yuchio Yanagawa, Imre Vida, Agnieszka Münster-Wandowsk. BDNF Expression in Cortical GABAergic Interneurons. International journal of molecular sciences. vol 21. issue 5. 2020-11-25. PMID:32106593. |
rt-qpcr of samples obtained using laser capture microdissection (lcm) or fluorescence-activated cell sorting (facs) of hippocampal and cortical neurons further demonstrated the abundance of bdnf transcripts in both glutamatergic and gabaergic cells. |
2020-11-25 |
2023-08-13 |
mouse |
| Christopher B German. The Psilocybin-Telomere Hypothesis: An empirically falsifiable prediction concerning the beneficial neuropsychopharmacological effects of psilocybin on genetic aging. Medical hypotheses. vol 134. 2020-11-23. PMID:31634774. |
in order to substantiate the 'psilocybin-telomere hypothesis' potential neuropsychopharmacological, endocrinological, and genetic mechanisms of action are discussed (e.g., hpa-axis reactivity, hippocampal neurogenesis, neurotropic growth factors such as bdnf, 5-ht |
2020-11-23 |
2023-08-13 |
human |
| Maryam Rahmani, Farzaneh Rahmani, Nima Rezae. The Brain-Derived Neurotrophic Factor: Missing Link Between Sleep Deprivation, Insomnia, and Depression. Neurochemical research. vol 45. issue 2. 2020-11-23. PMID:31782101. |
this physiological response loses effectiveness with longer episodes or during chronic of total or selective rem sleep loss, which are associated with impaired hippocampal bdnf expression, impaired memory and cognition. |
2020-11-23 |
2023-08-13 |
Not clear |
| Maryam Rahmani, Farzaneh Rahmani, Nima Rezae. The Brain-Derived Neurotrophic Factor: Missing Link Between Sleep Deprivation, Insomnia, and Depression. Neurochemical research. vol 45. issue 2. 2020-11-23. PMID:31782101. |
chronic sleep deprivation and insomnia can act as an external stressors and result in depression, characterized by hippocampal bdnf downregulation along with disrupted frontal cortical bdnf expression, as well as reduced levels and impaired diurnal alterations in serum bdnf expression. |
2020-11-23 |
2023-08-13 |
Not clear |
| Maryam Rahmani, Farzaneh Rahmani, Nima Rezae. The Brain-Derived Neurotrophic Factor: Missing Link Between Sleep Deprivation, Insomnia, and Depression. Neurochemical research. vol 45. issue 2. 2020-11-23. PMID:31782101. |
acute rem sleep deprivation breaks the cycle by restoration of hippocampal, and possibly restoration of cortical and serum expression of bdnf. |
2020-11-23 |
2023-08-13 |
Not clear |
| Hongxia Che, Lingyu Zhang, Lin Ding, Wancui Xie, Xiaoming Jiang, Changhu Xue, Tiantian Zhang, Yuming Wan. EPA-enriched ethanolamine plasmalogen and EPA-enriched phosphatidylethanolamine enhance BDNF/TrkB/CREB signaling and inhibit neuronal apoptosis in vitro and in vivo. Food & function. vol 11. issue 2. 2020-11-23. PMID:32043504. |
in the present study, primary cultured hippocampal neurons and cognitive deficiency rats were used to compare the effects of epa-ppe and epa-pe on brain-derived neurotrophic factor (bdnf)/tropomyosin receptor kinase b (trkb)/camp response element-binding protein (creb) signaling and neuronal apoptosis. |
2020-11-23 |
2023-08-13 |
rat |
| Genevieve Saw, Kumar Krishna, Neelima Gupta, Tuck Wah Soong, Karthik Mallilankaraman, Sreedharan Sajikumar, S Thameem Dhee. Epigenetic regulation of microglial phosphatidylinositol 3-kinase pathway involved in long-term potentiation and synaptic plasticity in rats. Glia. vol 68. issue 3. 2020-11-19. PMID:31702864. |
however, ltp was rescued when the same hippocampal slices were treated with active pi3k or bdnf, indicating that microglial pi3k/akt signaling contributes to ltp and synaptic plasticity. |
2020-11-19 |
2023-08-13 |
rat |
| Yanhua Jiang, Yongjian Zhou, Hong Ma, Xuezhao Cao, Zhe Li, Fengshou Chen, Hongnan Wan. Autophagy Dysfunction and mTOR Hyperactivation Is Involved in Surgery: Induced Behavioral Deficits in Aged C57BL/6J Mice. Neurochemical research. vol 45. issue 2. 2020-11-17. PMID:31865521. |
brain derived neurotrophic factor (bdnf), synaptophysin, and tau hyperphosphorylation (t396) in the hippocampus were also examined. |
2020-11-17 |
2023-08-13 |
mouse |
| Yanhua Jiang, Yongjian Zhou, Hong Ma, Xuezhao Cao, Zhe Li, Fengshou Chen, Hongnan Wan. Autophagy Dysfunction and mTOR Hyperactivation Is Involved in Surgery: Induced Behavioral Deficits in Aged C57BL/6J Mice. Neurochemical research. vol 45. issue 2. 2020-11-17. PMID:31865521. |
rapamycin treatment restored autophagy function, attenuated phosphorylation of tau protein, and increased bdnf and synaptophysin expression in the hippocampus of surgical mice. |
2020-11-17 |
2023-08-13 |
mouse |
| Erling Hu, Huan Du, Sen Shang, Yali Zhang, Xiaoyun L. Beta-Hydroxybutyrate Enhances BDNF Expression by Increasing H3K4me3 and Decreasing H2AK119ub in Hippocampal Neurons. Frontiers in neuroscience. vol 14. 2020-11-17. PMID:33192276. |
beta-hydroxybutyrate enhances bdnf expression by increasing h3k4me3 and decreasing h2ak119ub in hippocampal neurons. |
2020-11-17 |
2023-08-13 |
Not clear |