| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rachel Anne Hill, Adrienne Mary Grech, Michael J Notaras, Mauricio Sepulveda, Maarten van den Buus. Brain-Derived Neurotrophic Factor Val66Met polymorphism interacts with adolescent stress to alter hippocampal interneuron density and dendritic morphology in mice. Neurobiology of stress. vol 13. 2020-12-22. PMID:33344708. |
parvalbumin-positive interneurons were unchanged between genotype groups, however bdnf val66met genotype influenced the dendritic volume, branch level and spine density of parvalbumin interneurons differentially across hippocampal subregions. |
2020-12-22 |
2023-08-13 |
mouse |
| Qingfei Chen, Feifei Wang, Yunchao Zhang, Yan Liu, Li An, Zhongliang Ma, Jingzhong Zhang, Shuang Y. Neonatal DEX exposure leads to hyperanxious and depressive-like behaviors as well as a persistent reduction of BDNF expression in developmental stages. Biochemical and biophysical research communications. vol 527. issue 1. 2020-12-21. PMID:32446386. |
dexamethaone (dex) is indicated for a number of conditions in perinatal medicine, however, the long-term impact of early-life dex exposure on bdnf expression in hippocampus remains unknown. |
2020-12-21 |
2023-08-13 |
Not clear |
| Qingfei Chen, Feifei Wang, Yunchao Zhang, Yan Liu, Li An, Zhongliang Ma, Jingzhong Zhang, Shuang Y. Neonatal DEX exposure leads to hyperanxious and depressive-like behaviors as well as a persistent reduction of BDNF expression in developmental stages. Biochemical and biophysical research communications. vol 527. issue 1. 2020-12-21. PMID:32446386. |
however, the bdnf mrna and bdnf protein levels were significantly reduced in all the hippocampal subregions during the developmental stages, including the perinatal period and puberty. |
2020-12-21 |
2023-08-13 |
Not clear |
| Qingfei Chen, Feifei Wang, Yunchao Zhang, Yan Liu, Li An, Zhongliang Ma, Jingzhong Zhang, Shuang Y. Neonatal DEX exposure leads to hyperanxious and depressive-like behaviors as well as a persistent reduction of BDNF expression in developmental stages. Biochemical and biophysical research communications. vol 527. issue 1. 2020-12-21. PMID:32446386. |
we conclude that early life dex exposure leads to a persistent disturbance of bdnf signaling during the developmental stages, which might be associated with the life-long impairment of hippocampal function. |
2020-12-21 |
2023-08-13 |
Not clear |
| Wenzhu Wang, Xu Liu, Zhengyi Yang, Hui Shen, Lixu Liu, Yan Yu, Tong Zhan. Levodopa Improves Cognitive Function and the Deficits of Structural Synaptic Plasticity in Hippocampus Induced by Global Cerebral Ischemia/Reperfusion Injury in Rats. Frontiers in neuroscience. vol 14. 2020-12-18. PMID:33328857. |
the results showed that levodopa improved the neurological function and learning and memory of rats after global cerebral ischemia/reperfusion injury, improved the integrity of white matter, and density of gray matter in the hippocampus, increased the number of synapses, reduced the delayed neuronal death, and increased the expression of synaptic plasticity-related proteins (bdnf, trkb, psd95, and drebrin) in the hippocampus. |
2020-12-18 |
2023-08-13 |
rat |
| Natalie Baruch-Eliyahu, Vladislav Rud, Alex Braiman, Esther Prie. Telomerase increasing compound protects hippocampal neurons from amyloid beta toxicity by enhancing the expression of neurotrophins and plasticity related genes. Scientific reports. vol 9. issue 1. 2020-12-17. PMID:31792359. |
gap43, neun, syp, neurotrophic factors (ngf, bdnf), beta-catenin and cyclin-d1 expression were increased in the hippocampus of ags treated mice. |
2020-12-17 |
2023-08-13 |
mouse |
| Yuichi Abe, Masanori Honsho, Ryoko Kawaguchi, Takashi Matsuzaki, Yayoi Ichiki, Masashi Fujitani, Kazushirou Fujiwara, Masaaki Hirokane, Masahide Oku, Yasuyoshi Sakai, Toshihide Yamashita, Yukio Fujik. A peroxisome deficiency-induced reductive cytosol state up-regulates the brain-derived neurotrophic factor pathway. The Journal of biological chemistry. vol 295. issue 16. 2020-12-17. PMID:32165495. |
results from a noncontact co-culture system consisting of primary hippocampal neurons with glial cells revealed that a peroxisome-deficient astrocytic cell line secretes increased levels of brain-derived neurotrophic factor (bdnf), resulting in axonal branching of the neurons. |
2020-12-17 |
2023-08-13 |
Not clear |
| Brendan B McAllister, Nicoline Bihelek, Richelle Mychasiuk, Richard H Dyc. Brain-derived Neurotrophic Factor and TrkB Levels in Mice that Lack Vesicular Zinc: Effects of Age and Sex. Neuroscience. vol 425. 2020-12-15. PMID:31785352. |
in the present study, we measured bdnf and trkb levels in the hippocampus and neocortex, comparing wild type and znt3 knockout mice of both sexes at two ages (5 and 12 weeks). |
2020-12-15 |
2023-08-13 |
mouse |
| Brendan B McAllister, Nicoline Bihelek, Richelle Mychasiuk, Richard H Dyc. Brain-derived Neurotrophic Factor and TrkB Levels in Mice that Lack Vesicular Zinc: Effects of Age and Sex. Neuroscience. vol 425. 2020-12-15. PMID:31785352. |
and in females, but not males, znt3 ko mice exhibited great hippocampal bdnf mrna expression than wild type mice. |
2020-12-15 |
2023-08-13 |
mouse |
| Francis L Pazini, Julia M Rosa, Anderson Camargo, Daiane B Fraga, Morgana Moretti, Aline Siteneski, Ana Lúcia S Rodrigue. mTORC1-dependent signaling pathway underlies the rapid effect of creatine and ketamine in the novelty-suppressed feeding test. Chemico-biological interactions. vol 332. 2020-12-11. PMID:33022268. |
biochemical analyses included hippocampal bdnf level (elisa) and total and phospho-mtorc1 (ser |
2020-12-11 |
2023-08-13 |
mouse |
| Jin-Chul Heo, Ji-Ae Park, Dae-Kwang Kim, Jong-Ha Le. Photobiomodulation (660 nm) therapy reduces oxidative stress and induces BDNF expression in the hippocampus. Scientific reports. vol 9. issue 1. 2020-12-10. PMID:31300736. |
photobiomodulation (660 nm) therapy reduces oxidative stress and induces bdnf expression in the hippocampus. |
2020-12-10 |
2023-08-13 |
mouse |
| Jin-Chul Heo, Ji-Ae Park, Dae-Kwang Kim, Jong-Ha Le. Photobiomodulation (660 nm) therapy reduces oxidative stress and induces BDNF expression in the hippocampus. Scientific reports. vol 9. issue 1. 2020-12-10. PMID:31300736. |
this study assessed the anti-oxidative effect, the expression of bdnf and antioxidant enzymes, as well as the activation of camp response element binding (creb) and extracellular signal-regulated kinase (erk) signal transduction pathways assess using a hippocampal cell line (ht-22) and mouse organotypic hippocampal tissues by pbmt (led, 660 nm, 20 mw/cm |
2020-12-10 |
2023-08-13 |
mouse |
| Kellen Ugioni Simon, Elias Wiggers Neto, Natalia Dos Santos Tramontin, Paula Bortoluzzi Canteiro, Barbara da Costa Pereira, Rubya Pereira Zaccaron, Paulo Cesar Lock Silveira, Alexandre Pastoris Mulle. Intranasal insulin treatment modulates the neurotropic, inflammatory, and oxidant mechanisms in the cortex and hippocampus in a low-grade inflammation model. Peptides. vol 123. 2020-12-10. PMID:31639435. |
in the hippocampus, in insulin significantly decreased the bdnf level. |
2020-12-10 |
2023-08-13 |
mouse |
| Hsin-Yi Hsieh, Yu-Chieh Chen, Mei-Hsin Hsu, Hong-Ren Yu, Chung-Hao Su, You-Lin Tain, Li-Tung Huang, Jiunn-Ming Shee. Maternal Iron Deficiency Programs Offspring Cognition and Its Relationship with Gastrointestinal Microbiota and Metabolites. International journal of environmental research and public health. vol 17. issue 17. 2020-12-09. PMID:32825437. |
we used a sprague-dawley rat model of a maternal low-iron diet to explore the changes in cognition, dorsal hippocampal brain-derived neurotrophic factor (bdnf) and related pathways, gut microbiota, and related metabolites in adult male offspring. |
2020-12-09 |
2023-08-13 |
rat |
| Juliana C S Chaves, Felippe T Machado, Michael F Almeida, Tatiana B Bacovsky, Merari F R Ferrar. microRNAs expression correlates with levels of APP, DYRK1A, hyperphosphorylated Tau and BDNF in the hippocampus of a mouse model for Down syndrome during ageing. Neuroscience letters. vol 714. 2020-12-07. PMID:31605772. |
micrornas expression correlates with levels of app, dyrk1a, hyperphosphorylated tau and bdnf in the hippocampus of a mouse model for down syndrome during ageing. |
2020-12-07 |
2023-08-13 |
mouse |
| Juliana C S Chaves, Felippe T Machado, Michael F Almeida, Tatiana B Bacovsky, Merari F R Ferrar. microRNAs expression correlates with levels of APP, DYRK1A, hyperphosphorylated Tau and BDNF in the hippocampus of a mouse model for Down syndrome during ageing. Neuroscience letters. vol 714. 2020-12-07. PMID:31605772. |
in this study, we investigated the association among mirnas mir-17, -20a, -101, -106b, -199b, -26a, 26b and some of their target mrnas such as app, dyrk1a and bdnf, as well as the levels of hyperphosphorylated tau in the hippocampus of a 2 and 5 months old mice model of trisomy 21 (ts65dn). |
2020-12-07 |
2023-08-13 |
mouse |
| Jariya Umka Welbat, Salinee Naewla, Wanassanan Pannangrong, Apiwat Sirichoat, Anusara Aranarochana, Peter Wigmor. Neuroprotective effects of hesperidin against methotrexate-induced changes in neurogenesis and oxidative stress in the adult rat. Biochemical pharmacology. vol 178. 2020-12-07. PMID:32522593. |
treatment with mtx also increased malondialdehyde (mda) in both the hippocampus and prefrontal cortex and decreased levels of brain-derived neurotropic factor (bdnf) and nuclear factor erythroid 2-related factor 2 (nrf2) in the hippocampus and prefrontal cortex. |
2020-12-07 |
2023-08-13 |
rat |
| Zuntao Wu, Lin Bai, Runqi Tu, Lijie Zhang, Yue Ba, Huizhen Zhang, Xing Li, Xuemin Cheng, Wenjie Li, Hui Huan. Disruption of synaptic expression pattern and age-related DNA oxidation in a neuronal model of lead-induced toxicity. Environmental toxicology and pharmacology. vol 76. 2020-12-04. PMID:32058320. |
in the hippocampus of lead exposed mice at three age nodes, the expression of brain-derived neurotrophic factor precursor (probdnf) increased, while that of mature bdnf (mbdnf), camp-response element binding protein (creb) and phosphorylated creb (pcreb) decreased compared with the control group. |
2020-12-04 |
2023-08-13 |
mouse |
| Brittany E Dong, Hao Chen, Kazuko Sakat. BDNF deficiency and enriched environment treatment affect neurotransmitter gene expression differently across ages. Journal of neurochemistry. vol 154. issue 1. 2020-12-04. PMID:32222968. |
high-throughput quantitative reverse transcription polymerase chain reaction measured expression of 81 genes for dopamine, adrenaline, serotonin, gamma aminobutyric acid, glutamate, acetylcholine, and bdnf systems in the frontal cortex (fc) and hippocampus. |
2020-12-04 |
2023-08-13 |
mouse |
| Zhen Jin, Kyung Eun Kim, Hyun Joo Shin, Eun Ae Jeong, Kyung-Ah Park, Jong Youl Lee, Hyeong Seok An, Eun Bee Choi, Jae Hun Jeong, Woori Kwak, Gu Seob Ro. Hippocampal Lipocalin 2 Is Associated With Neuroinflammation and Iron-Related Oxidative Stress in ob/ob Mice. Journal of neuropathology and experimental neurology. vol 79. issue 5. 2020-12-04. PMID:32296847. |
using rna-seq analysis, we found that neurodegeneration- sortilin-related receptor 1 (sorl1) and brain-derived neurotrophic factor (bdnf) genes were significantly reduced in the hippocampus of ob/ob mice. |
2020-12-04 |
2023-08-13 |
mouse |