| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lin Wang, Xi-Xi Li, Xi Chen, Xiao-Yan Qin, Elissavet Kardami, Yong Chen. Antidepressant-Like Effects of Low- and High-Molecular Weight FGF-2 on Chronic Unpredictable Mild Stress Mice. Frontiers in molecular neuroscience. vol 11. 2020-10-01. PMID:30369869. |
interestingly, hmw fgf-2 enhanced the activity of the brain-derived neurotrophic factor (bdnf) to a greater extent than did lmw fgf-2 in the hippocampus. |
2020-10-01 |
2023-08-13 |
mouse |
| Cong Lu, Yan Wang, Teng Xu, Qi Li, Donghui Wang, Lijing Zhang, Bei Fan, Fengzhong Wang, Xinmin Li. Genistein Ameliorates Scopolamine-Induced Amnesia in Mice Through the Regulation of the Cholinergic Neurotransmission, Antioxidant System and the ERK/CREB/BDNF Signaling. Frontiers in pharmacology. vol 9. 2020-10-01. PMID:30369882. |
furthermore, ge was found to significantly upregulate the expression levels of p-erk, p-creb and bdnf proteins in the hippocampus of scop-treated mice. |
2020-10-01 |
2023-08-13 |
mouse |
| Yin-Xiu Han, Chen Tao, Xin-Ran Gao, Le-le Wang, Fu-Hao Jiang, Chong Wang, Ke Fang, Xing-Xing Chen, Zheng Chen, Jin-Fang G. BDNF-Related Imbalance of Copine 6 and Synaptic Plasticity Markers Couples With Depression-Like Behavior and Immune Activation in CUMS Rats. Frontiers in neuroscience. vol 12. 2020-10-01. PMID:30429764. |
the plasma concentrations of c-reactive protein (crp) and interleukin-6 (il-6) were measured, and the protein expressions of brain-derived neurotrophic factor (bdnf), copine 6, and synaptic plasticity markers in the hippocampus and the pfc were also detected. |
2020-10-01 |
2023-08-13 |
rat |
| Yin-Xiu Han, Chen Tao, Xin-Ran Gao, Le-le Wang, Fu-Hao Jiang, Chong Wang, Ke Fang, Xing-Xing Chen, Zheng Chen, Jin-Fang G. BDNF-Related Imbalance of Copine 6 and Synaptic Plasticity Markers Couples With Depression-Like Behavior and Immune Activation in CUMS Rats. Frontiers in neuroscience. vol 12. 2020-10-01. PMID:30429764. |
moreover, the protein expressions of bdnf, copine 6, and synapsin i were decreased in both the hippocampus and the pfc of cums rats, and the protein expression of synaptotagmin i was decreased in the hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Yin-Xiu Han, Chen Tao, Xin-Ran Gao, Le-le Wang, Fu-Hao Jiang, Chong Wang, Ke Fang, Xing-Xing Chen, Zheng Chen, Jin-Fang G. BDNF-Related Imbalance of Copine 6 and Synaptic Plasticity Markers Couples With Depression-Like Behavior and Immune Activation in CUMS Rats. Frontiers in neuroscience. vol 12. 2020-10-01. PMID:30429764. |
furthermore, pearson's test revealed a potential relationship between the depression-like behavior, the plasma crp concentration, and the protein expressions of bdnf, copine 6, synapsin i, or synaptotagmin i in the hippocampus or the pfc. |
2020-10-01 |
2023-08-13 |
rat |
| Joseph M Hall, Fernando Gomez-Pinilla, Lisa M Savag. Nerve Growth Factor Is Responsible for Exercise-Induced Recovery of Septohippocampal Cholinergic Structure and Function. Frontiers in neuroscience. vol 12. 2020-10-01. PMID:30443202. |
to determine which neurotrophin, brain-derived neurotrophic factor (bdnf) or nerve growth factor (ngf), is critical for exercise-induced cholinergic improvements, control and amnestic rats had either ngf or bdnf sequestered by trka-igg or trkb-igg coated microbeads placed within the dorsal hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Hao Ma, Weiping Wang, Shaofeng Xu, Ling Wang, Xiaoliang Wan. Potassium 2-(1-hydroxypentyl)-benzoate improves depressive-like behaviors in rat model. Acta pharmaceutica Sinica. B. vol 8. issue 6. 2020-10-01. PMID:30505657. |
meanwhile, phpb normalized the enhanced level of serum corticosterone, improved hippocampal and serum bdnf levels, as well as p-creb level in hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Pan Meng, Yuanshan Han, Qin Yang, Hui Yang, Qing Zhu, Xiaoyuan Lin, Xiuli Zhang, Hongqing Zhao, Zhuo Liu, Jian Liu, Lin Tang, Weixu Luo, Yuhong Wan. Xiaoyao Kangai Jieyu Fang, a Chinese Herbal Formulation, Ameliorates Cancer-Related Depression Concurrent with Breast Cancer in Mice via Promoting Hippocampal Synaptic Plasticity. Evidence-based complementary and alternative medicine : eCAM. vol 2018. 2020-10-01. PMID:30581482. |
also, the pathological changes of the tumor, hippocampus, and the expressions of gr, nr2a, nr2b, camkii, creb, and bdnf were detected. |
2020-10-01 |
2023-08-13 |
mouse |
| Pan Meng, Yuanshan Han, Qin Yang, Hui Yang, Qing Zhu, Xiaoyuan Lin, Xiuli Zhang, Hongqing Zhao, Zhuo Liu, Jian Liu, Lin Tang, Weixu Luo, Yuhong Wan. Xiaoyao Kangai Jieyu Fang, a Chinese Herbal Formulation, Ameliorates Cancer-Related Depression Concurrent with Breast Cancer in Mice via Promoting Hippocampal Synaptic Plasticity. Evidence-based complementary and alternative medicine : eCAM. vol 2018. 2020-10-01. PMID:30581482. |
also, it reduced the content of cort, acth, crh, and ca125, ca153, cea in the blood, protected the pathological changes of the hippocampus and tumor, upregulated the expression of gr, creb, and bdnf in the hippocampus, and significantly decreased the expression of nr2a, nr2b, and camkii. |
2020-10-01 |
2023-08-13 |
mouse |
| Yu Zhao, Jinling Wang, Jiwei Du, Baixiang Li, Xingchun Gou, Jiannan Liu, Lichao Hou, Hanfei Sang, Bin Den. TAT-Ngn2 Enhances Cognitive Function Recovery and Regulates Caspase-Dependent and Mitochondrial Apoptotic Pathways After Experimental Stroke. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:30618628. |
furthermore, tat-ngn2 alleviated hippocampal neuronal damage and apoptosis, and inhibited the cytochrome c (cytc) leak from the mitochondria to the cytoplasm through regulating the expression levels of brain-derived neurotrophic factor (bdnf), phosphorylation tropomyosin-related kinase b (ptrkb), bcl-2, bax and cleaved caspase-3 after reperfusion injury |
2020-10-01 |
2023-08-13 |
mouse |
| Guillermo Moya-Alvarado, Andres Gonzalez, Nicolas Stuardo, Francisca C Bronfma. Brain-Derived Neurotrophic Factor (BDNF) Regulates Rab5-Positive Early Endosomes in Hippocampal Neurons to Induce Dendritic Branching. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:30618640. |
brain-derived neurotrophic factor (bdnf) regulates rab5-positive early endosomes in hippocampal neurons to induce dendritic branching. |
2020-10-01 |
2023-08-13 |
Not clear |
| Guillermo Moya-Alvarado, Andres Gonzalez, Nicolas Stuardo, Francisca C Bronfma. Brain-Derived Neurotrophic Factor (BDNF) Regulates Rab5-Positive Early Endosomes in Hippocampal Neurons to Induce Dendritic Branching. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:30618640. |
the objective of our work was to study the regulation of rab5-positive endosomes by bdnf at different levels, including dynamic, activity and protein levels in hippocampal neurons. |
2020-10-01 |
2023-08-13 |
Not clear |
| Guillermo Moya-Alvarado, Andres Gonzalez, Nicolas Stuardo, Francisca C Bronfma. Brain-Derived Neurotrophic Factor (BDNF) Regulates Rab5-Positive Early Endosomes in Hippocampal Neurons to Induce Dendritic Branching. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:30618640. |
long-term treatment of hippocampal neurons with bdnf increased the protein levels of rab5 and rab11 in an mtor-dependent manner. |
2020-10-01 |
2023-08-13 |
Not clear |
| Juliane Zemdegs, Quentin Rainer, Cindy P Grossmann, Delphine Rousseau-Ralliard, Alain Grynberg, Eliane Ribeiro, Bruno P Guiar. Anxiolytic- and Antidepressant-Like Effects of Fish Oil-Enriched Diet in Brain-Derived Neurotrophic Factor Deficient Mice. Frontiers in neuroscience. vol 12. 2020-10-01. PMID:30622454. |
in contrast, low bdnf levels and hippocampal atrophy were observed in animal models of depression. |
2020-10-01 |
2023-08-13 |
mouse |
| Wen-Bo Zhou, Zong-Ning Miao, Bin Zhang, Wei Long, Fang-Xiu Zheng, Jing Kong, Bin Y. Luteolin induces hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome. Neural regeneration research. vol 14. issue 4. 2020-10-01. PMID:30632501. |
western blot assay was used to analyze the protein levels of brain-derived neurotrophic factor (bdnf) and phospho-extracellular signal-regulated kinase 1/2 (p-erk1/2) in the hippocampus. |
2020-10-01 |
2023-08-13 |
mouse |
| Mengmeng You, Yongming Pan, Yichen Liu, Yifan Chen, Yuqi Wu, Juanjuan Si, Kai Wang, Fuliang H. Royal Jelly Alleviates Cognitive Deficits and β-Amyloid Accumulation in APP/PS1 Mouse Model Via Activation of the cAMP/PKA/CREB/BDNF Pathway and Inhibition of Neuronal Apoptosis. Frontiers in aging neuroscience. vol 10. 2020-10-01. PMID:30687079. |
importantly, hippocampal cyclic adenosine monophosphate (camp), p-pka, p-creb and bdnf levels were significantly increased in the app/ps1 mice after rj treatment, indicating that the camp/pka/creb/bdnf pathway might be related to the ameliorative effect of rj on cognitive decline. |
2020-10-01 |
2023-08-13 |
mouse |
| Michael Zhang, Kennett D Radford, Mercedes Driscoll, Salsabila Purnomo, Jean Kim, Kwang H Cho. Effects of subanesthetic intravenous ketamine infusion on neuroplasticity-related proteins in the prefrontal cortex, amygdala, and hippocampus of Sprague-Dawley rats. IBRO reports. vol 6. 2020-10-01. PMID:30723838. |
the 10 mg/kg ketamine infusion increased bdnf levels in the amygdala, but decreased perk levels in the mpfc and hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Emanuela Paldino, Carmela Giampà, Elena Montagna, Cecilia Angeloni, Francesca R Fusc. Modulation of Phospho-CREB by Systemically Administered Recombinant BDNF in the Hippocampus of the R6/2 Mouse Model of Huntington's Disease. Neuroscience journal. vol 2019. 2020-10-01. PMID:30881980. |
modulation of phospho-creb by systemically administered recombinant bdnf in the hippocampus of the r6/2 mouse model of huntington's disease. |
2020-10-01 |
2023-08-13 |
mouse |
| Neus Gomila Pelegri, Catherine A Gorrie, Jerran Santo. Rat Hippocampal Neural Stem Cell Modulation Using PDGF, VEGF, PDGF/VEGF, and BDNF. Stem cells international. vol 2019. 2020-10-01. PMID:31011333. |
rat hippocampal neural stem cell modulation using pdgf, vegf, pdgf/vegf, and bdnf. |
2020-10-01 |
2023-08-13 |
rat |
| Ana Paula De Vincenti, Antonella S Ríos, Gustavo Paratcha, Fernanda Ledd. Mechanisms That Modulate and Diversify BDNF Functions: Implications for Hippocampal Synaptic Plasticity. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31024262. |
mechanisms that modulate and diversify bdnf functions: implications for hippocampal synaptic plasticity. |
2020-10-01 |
2023-08-13 |
Not clear |