| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ivani Credidio Trombetta, José Roberto DeMoura, Cleber Rene Alves, Renato Carbonari-Brito, Felipe Xerez Cepeda, José Ribeiro Lemo. Serum Levels of BDNF in Cardiovascular Protection and in Response to Exercise. Arquivos brasileiros de cardiologia. vol 115. issue 2. 2020-12-04. PMID:32876194. |
bdnf is a neurotrophin found at high concentrations in the hippocampus and cerebral cortex and is considered a key molecule for the maintenance of synaptic plasticity and survival of neuronal cells. |
2020-12-04 |
2023-08-13 |
Not clear |
| Ning Jiang, Haixia Wang, Jingwei Lv, Qiong Wang, Cong Lu, Yujiao Li, Xinmin Li. Dammarane sapogenins attenuates stress-induced anxiety-like behaviors by upregulating ERK/CREB/BDNF pathways. Phytotherapy research : PTR. vol 34. issue 10. 2020-11-30. PMID:32431006. |
treatment with ds significantly upregulated bdnf (brain-derived neurotrophic factor), p-creb/creb and p-erk1/2/erk1/2 protein expression in the hippocampus and prefrontal cortex of csds mice. |
2020-11-30 |
2023-08-13 |
mouse |
| Natalia Dos Santos Tramontin, Sabrina da Silva, Rychard Arruda, Kellen Simon Ugioni, Paula Bortuluzzi Canteiro, Gustavo de Bem Silveira, Carolini Mendes, Paulo Cesar Lock Silveira, Alexandre Pastoris Mulle. Gold Nanoparticles Treatment Reverses Brain Damage in Alzheimer's Disease Model. Molecular neurobiology. vol 57. issue 2. 2020-11-25. PMID:31612296. |
neurotrophic factors (bdnf and ngf- β) in the cortex and hippocampus were decreased by oa. |
2020-11-25 |
2023-08-13 |
rat |
| Federico José Barreda Tomás, Paul Turko, Heike Heilmann, Thorsten Trimbuch, Yuchio Yanagawa, Imre Vida, Agnieszka Münster-Wandowsk. BDNF Expression in Cortical GABAergic Interneurons. International journal of molecular sciences. vol 21. issue 5. 2020-11-25. PMID:32106593. |
rt-qpcr of samples obtained using laser capture microdissection (lcm) or fluorescence-activated cell sorting (facs) of hippocampal and cortical neurons further demonstrated the abundance of bdnf transcripts in both glutamatergic and gabaergic cells. |
2020-11-25 |
2023-08-13 |
mouse |
| Christopher B German. The Psilocybin-Telomere Hypothesis: An empirically falsifiable prediction concerning the beneficial neuropsychopharmacological effects of psilocybin on genetic aging. Medical hypotheses. vol 134. 2020-11-23. PMID:31634774. |
in order to substantiate the 'psilocybin-telomere hypothesis' potential neuropsychopharmacological, endocrinological, and genetic mechanisms of action are discussed (e.g., hpa-axis reactivity, hippocampal neurogenesis, neurotropic growth factors such as bdnf, 5-ht |
2020-11-23 |
2023-08-13 |
human |
| Maryam Rahmani, Farzaneh Rahmani, Nima Rezae. The Brain-Derived Neurotrophic Factor: Missing Link Between Sleep Deprivation, Insomnia, and Depression. Neurochemical research. vol 45. issue 2. 2020-11-23. PMID:31782101. |
this physiological response loses effectiveness with longer episodes or during chronic of total or selective rem sleep loss, which are associated with impaired hippocampal bdnf expression, impaired memory and cognition. |
2020-11-23 |
2023-08-13 |
Not clear |
| Maryam Rahmani, Farzaneh Rahmani, Nima Rezae. The Brain-Derived Neurotrophic Factor: Missing Link Between Sleep Deprivation, Insomnia, and Depression. Neurochemical research. vol 45. issue 2. 2020-11-23. PMID:31782101. |
chronic sleep deprivation and insomnia can act as an external stressors and result in depression, characterized by hippocampal bdnf downregulation along with disrupted frontal cortical bdnf expression, as well as reduced levels and impaired diurnal alterations in serum bdnf expression. |
2020-11-23 |
2023-08-13 |
Not clear |
| Maryam Rahmani, Farzaneh Rahmani, Nima Rezae. The Brain-Derived Neurotrophic Factor: Missing Link Between Sleep Deprivation, Insomnia, and Depression. Neurochemical research. vol 45. issue 2. 2020-11-23. PMID:31782101. |
acute rem sleep deprivation breaks the cycle by restoration of hippocampal, and possibly restoration of cortical and serum expression of bdnf. |
2020-11-23 |
2023-08-13 |
Not clear |
| Hongxia Che, Lingyu Zhang, Lin Ding, Wancui Xie, Xiaoming Jiang, Changhu Xue, Tiantian Zhang, Yuming Wan. EPA-enriched ethanolamine plasmalogen and EPA-enriched phosphatidylethanolamine enhance BDNF/TrkB/CREB signaling and inhibit neuronal apoptosis in vitro and in vivo. Food & function. vol 11. issue 2. 2020-11-23. PMID:32043504. |
in the present study, primary cultured hippocampal neurons and cognitive deficiency rats were used to compare the effects of epa-ppe and epa-pe on brain-derived neurotrophic factor (bdnf)/tropomyosin receptor kinase b (trkb)/camp response element-binding protein (creb) signaling and neuronal apoptosis. |
2020-11-23 |
2023-08-13 |
rat |
| Genevieve Saw, Kumar Krishna, Neelima Gupta, Tuck Wah Soong, Karthik Mallilankaraman, Sreedharan Sajikumar, S Thameem Dhee. Epigenetic regulation of microglial phosphatidylinositol 3-kinase pathway involved in long-term potentiation and synaptic plasticity in rats. Glia. vol 68. issue 3. 2020-11-19. PMID:31702864. |
however, ltp was rescued when the same hippocampal slices were treated with active pi3k or bdnf, indicating that microglial pi3k/akt signaling contributes to ltp and synaptic plasticity. |
2020-11-19 |
2023-08-13 |
rat |
| Yanhua Jiang, Yongjian Zhou, Hong Ma, Xuezhao Cao, Zhe Li, Fengshou Chen, Hongnan Wan. Autophagy Dysfunction and mTOR Hyperactivation Is Involved in Surgery: Induced Behavioral Deficits in Aged C57BL/6J Mice. Neurochemical research. vol 45. issue 2. 2020-11-17. PMID:31865521. |
brain derived neurotrophic factor (bdnf), synaptophysin, and tau hyperphosphorylation (t396) in the hippocampus were also examined. |
2020-11-17 |
2023-08-13 |
mouse |
| Yanhua Jiang, Yongjian Zhou, Hong Ma, Xuezhao Cao, Zhe Li, Fengshou Chen, Hongnan Wan. Autophagy Dysfunction and mTOR Hyperactivation Is Involved in Surgery: Induced Behavioral Deficits in Aged C57BL/6J Mice. Neurochemical research. vol 45. issue 2. 2020-11-17. PMID:31865521. |
rapamycin treatment restored autophagy function, attenuated phosphorylation of tau protein, and increased bdnf and synaptophysin expression in the hippocampus of surgical mice. |
2020-11-17 |
2023-08-13 |
mouse |
| Erling Hu, Huan Du, Sen Shang, Yali Zhang, Xiaoyun L. Beta-Hydroxybutyrate Enhances BDNF Expression by Increasing H3K4me3 and Decreasing H2AK119ub in Hippocampal Neurons. Frontiers in neuroscience. vol 14. 2020-11-17. PMID:33192276. |
beta-hydroxybutyrate enhances bdnf expression by increasing h3k4me3 and decreasing h2ak119ub in hippocampal neurons. |
2020-11-17 |
2023-08-13 |
Not clear |
| Eun-Sang Ji, You-Mi Kim, Young Jun Ko, Seung-Soo Bae. Treadmill exercise in obese maternal rats during pregnancy improves short-term memory through neurogenesis in the hippocampus of rat pups. Journal of exercise rehabilitation. vol 16. issue 5. 2020-11-13. PMID:33178640. |
expression of brain-derived neurotrophic factor (bdnf) and tyrosine kinase b (trkb) in the hippocampus was decreased in the rat pups born to obese maternal rats. |
2020-11-13 |
2023-08-13 |
rat |
| Xiang Li, Yuan-Yuan Zhuang, Lei Wu, Ming Xie, Hong-Feng Gu, Bo Wang, Xiao-Qing Tan. Hydrogen Sulfide Ameliorates Cognitive Dysfunction in Formaldehyde-Exposed Rats: Involvement in the Upregulation of Brain-Derived Neurotrophic Factor. Neuropsychobiology. vol 79. issue 2. 2020-11-12. PMID:31550727. |
to investigate whether hydrogen sulfide (h2s) counteracts formaldehyde (fa)-induced cognitive defects and whether the underlying mechanism is involved in the upregulation of hippocampal brain-derived neurotrophic factor (bdnf) expression. |
2020-11-12 |
2023-08-13 |
rat |
| Takafumi Mizushige, Tomoki Uchida, Kousaku Ohinat. Dipeptide tyrosyl-leucine exhibits antidepressant-like activity in mice. Scientific reports. vol 10. issue 1. 2020-11-11. PMID:32042019. |
yl did not affect hippocampal mrna and protein expression of bdnf, which is a regulatory factor of both neurogenesis and depression-like behavior. |
2020-11-11 |
2023-08-13 |
mouse |
| Takafumi Mizushige, Tomoki Uchida, Kousaku Ohinat. Dipeptide tyrosyl-leucine exhibits antidepressant-like activity in mice. Scientific reports. vol 10. issue 1. 2020-11-11. PMID:32042019. |
our findings demonstrate that yl exhibits an antidepressant-like effect, moderates the stress response, and induces hippocampal neuronal proliferation through a signal pathway independent of bdnf. |
2020-11-11 |
2023-08-13 |
mouse |
| Farshid Sadegzadeh, Nona Sakhaie, Raziyeh Dehghany, Omid Adak, Hakimeh Saadat. Effects of adolescent administration of fluoxetine on novel object recognition memory, anxiety-like behaviors, and hippocampal brain-derived neurotrophic factor level. Life sciences. vol 260. 2020-11-10. PMID:32841662. |
the present study was designed to examine the effects of chronic flx exposure during adolescence on cognitive function, anxiety-like behaviors, and hippocampal brain-derived neurotrophic factor (bdnf) mrna expression among adult male and female rats. |
2020-11-10 |
2023-08-13 |
rat |
| Xi Fang, Chun Yang, Shan Li, Gaofeng Zhan, Jie Zhang, Niannian Huang, Xiangxi Du, Hui Xu, Kenji Hashimoto, Ailin Lu. Brain-derived neurotrophic factor-TrkB signaling in the medial prefrontal cortex plays a role in the anhedonia-like phenotype after spared nerve injury. European archives of psychiatry and clinical neuroscience. vol 270. issue 2. 2020-11-06. PMID:29882089. |
furthermore, tissue levels of bdnf in the hippocampus, l2-5 spinal cord, muscle, and liver from both rats with or without anhedonia-like phenotype were lower compared with those of sham-operated rats. |
2020-11-06 |
2023-08-13 |
rat |
| Philine Marchetta, Daria Savitska, Angelika Kübler, Giulia Asola, Marie Manthey, Dorit Möhrle, Thomas Schimmang, Lukas Rüttiger, Marlies Knipper, Wibke Singe. Age-Dependent Auditory Processing Deficits after Cochlear Synaptopathy Depend on Auditory Nerve Latency and the Ability of the Brain to Recruit LTP/BDNF. Brain sciences. vol 10. issue 10. 2020-11-03. PMID:33036168. |
it was also found that central neural gain after acoustic trauma was linked to hippocampal long-term potentiation (ltp) and upregulation of brain-derived neurotrophic factor (bdnf). |
2020-11-03 |
2023-08-13 |
mouse |