| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kandaswamy Selvakumar, Senthamilselvan Bavithra, Gunasekaran Krishnamoorthy, Jagadeesan Arunakara. Impact of quercetin on tight junctional proteins and BDNF signaling molecules in hippocampus of PCBs-exposed rats. Interdisciplinary toxicology. vol 11. issue 4. 2020-10-01. PMID:31762681. |
the study is to assess the role of quercetin on serum pcb, estradiol and testosterone levels and mrna expressions of estrogen receptor α and β, tjps and bdnf signaling molecules on the hippocampus of pcbs-exposed rats. |
2020-10-01 |
2023-08-13 |
rat |
| Kandaswamy Selvakumar, Senthamilselvan Bavithra, Gunasekaran Krishnamoorthy, Jagadeesan Arunakara. Impact of quercetin on tight junctional proteins and BDNF signaling molecules in hippocampus of PCBs-exposed rats. Interdisciplinary toxicology. vol 11. issue 4. 2020-10-01. PMID:31762681. |
tjps and bdnf signalling molecules were decreased in hippocampus of pcb treated rats. |
2020-10-01 |
2023-08-13 |
rat |
| Shoko Shimizu, Yugo Ishino, Takashi Takeda, Masaya Tohyama, Shingo Miyat. Antidepressive Effects of Kamishoyosan through 5-HT1AReceptor and PKA-CREB-BDNF Signaling in the Hippocampus in Postmenopausal Depression-Model Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2019. 2020-10-01. PMID:31781286. |
as previous studies have implicated dysfunction of the hippocampal 5-ht1a receptor (5-ht1ar) in depressive disorders, we also evaluated the effect of kss on 5-ht1ar expression and the protein kinase a- (pka-) camp response element-binding- (creb-) brain-derived neurotrophic factor (bdnf) signaling pathway in the hippocampus in this model. |
2020-10-01 |
2023-08-13 |
mouse |
| Shoko Shimizu, Yugo Ishino, Takashi Takeda, Masaya Tohyama, Shingo Miyat. Antidepressive Effects of Kamishoyosan through 5-HT1AReceptor and PKA-CREB-BDNF Signaling in the Hippocampus in Postmenopausal Depression-Model Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2019. 2020-10-01. PMID:31781286. |
furthermore, we found that kss treatment upregulated the expression levels of phosphorylated pka (p-pka), phosphorylated creb (p-creb), and bdnf in the hippocampus in chronic stress-exposed ovx mice. |
2020-10-01 |
2023-08-13 |
mouse |
| Constanza R Fuentealba, Jenny L Fiedler, Francisco A Peralta, Ana María Avalos, Felipe I Aguayo, Katherine P Morgado-Gallardo, Esteban E Aliag. Region-Specific Reduction of BDNF Protein and Transcripts in the Hippocampus of Juvenile Rats Prenatally Treated With Sodium Valproate. Frontiers in molecular neuroscience. vol 12. 2020-10-01. PMID:31787877. |
region-specific reduction of bdnf protein and transcripts in the hippocampus of juvenile rats prenatally treated with sodium valproate. |
2020-10-01 |
2023-08-13 |
rat |
| Constanza R Fuentealba, Jenny L Fiedler, Francisco A Peralta, Ana María Avalos, Felipe I Aguayo, Katherine P Morgado-Gallardo, Esteban E Aliag. Region-Specific Reduction of BDNF Protein and Transcripts in the Hippocampus of Juvenile Rats Prenatally Treated With Sodium Valproate. Frontiers in molecular neuroscience. vol 12. 2020-10-01. PMID:31787877. |
in order to contribute to this topic, we treated prenatal rats with valproate, a well-validated model of autism, to analyze bdnf levels in the hippocampus of juvenile rats. |
2020-10-01 |
2023-08-13 |
rat |
| Lone Diana Hørlyck, Julian Macoveanu, Maj Vinberg, Lars Vedel Kessing, Hartwig Roman Siebner, Kamilla Woznica Miskowia. The BDNF Val66Met Polymorphism Has No Effect on Encoding-Related Hippocampal Response But Influences Recall in Remitted Patients With Bipolar Disorder. Frontiers in psychiatry. vol 10. 2020-10-01. PMID:31866880. |
the bdnf val66met polymorphism has no effect on encoding-related hippocampal response but influences recall in remitted patients with bipolar disorder. |
2020-10-01 |
2023-08-13 |
Not clear |
| Liang Yang, Yong Wang, Nuomin Li, Bing Xu, Juanhui Duan, Chunxu Yuan, Qinfen Yuan, Qifan Yang, Hong Qing, Zhi Dai, Zhenzhen Qua. The Anti-Depression-Like Effects of Zhengtian Capsule Frontiers in pharmacology. vol 11. 2020-10-01. PMID:32982748. |
experimental results show that ztc (m 0.34 and h 0.7 g/kg) can elevate the proliferation of neural stem cells and gabaergic-type neurons in the hippocampus, promote the protein levels of bdnf, phosphorylated erk1/2, and creb, and inhibit the expression level of a key inflammation factor nfκb in a dose-dependent manner. |
2020-10-01 |
2023-08-13 |
Not clear |
| Xian-Zhe Dong, Dong-Xiao Wang, Bing-Ying Yu, Ping Liu, Yuan H. Kai-Xin-San, a traditional Chinese medicine formulation, exerts antidepressive and neuroprotective effects by promoting pCREB upstream pathways. Experimental and therapeutic medicine. vol 12. issue 5. 2020-09-30. PMID:27882154. |
in kxs rats, increased protein expression levels of pcreb, bdnf and tyrosine receptor kinase b (trkb) were observed in the hippocampus and prefrontal cortex, compared with the cms model group. |
2020-09-30 |
2023-08-13 |
rat |
| Maryam Radahmadi, Nasrin Hosseini, Hojjatallah Alaei, Mohammad Reza Sharif. The Effect of Preventive, Therapeutic and Protective Exercises on Hippocampal Memory Mediators in Stressed Rats. The Malaysian journal of medical sciences : MJMS. vol 23. issue 5. 2020-09-30. PMID:27904422. |
the present study focuses on the hippocampal corticosterone (cort), interleukin-1 beta (il-1β), glucose, and brain-derived neurotrophic factor (bdnf) levels in preventive, therapeutic, and protective exercises in stressful conditions. |
2020-09-30 |
2023-08-13 |
rat |
| Jitao Li, Xiaomeng Xie, Youhong Li, Xiao Liu, Xuemei Liao, Yun-Ai Su, Tianmei S. Differential Behavioral and Neurobiological Effects of Chronic Corticosterone Treatment in Adolescent and Adult Rats. Frontiers in molecular neuroscience. vol 10. 2020-09-30. PMID:28210212. |
these differential behavioral alterations were accompanied by opposite changes in the two age groups in the expression levels of brain-derived neurotrophic factor (bdnf), the phosphorylation of the obligatory subunit of the nmda receptor, glun1, and psd-95 in rat hippocampus. |
2020-09-30 |
2023-08-13 |
rat |
| Marta Weinstoc. Prenatal stressors in rodents: Effects on behavior. Neurobiology of stress. vol 6. 2020-09-30. PMID:28229104. |
however, like in humans with schizophrenia and depression, prenatal stress lowered hippocampal levels of bdnf, which were closely correlated with decreases in hippocampal long-term potentiation. |
2020-09-30 |
2023-08-13 |
mouse |
| Qing Cheng, Sang-Ho Song, George J Augustin. Calcium-Dependent and Synapsin-Dependent Pathways for the Presynaptic Actions of BDNF. Frontiers in cellular neuroscience. vol 11. 2020-09-30. PMID:28392759. |
we used cultured hippocampal neurons to determine the signaling pathways mediating brain-derived neurotrophic factor (bdnf) regulation of spontaneous glutamate and gaba release. |
2020-09-30 |
2023-08-13 |
mouse |
| Peng Zheng, Xiaohong Xu, Hongyan Zhao, Tingting Lv, Bailin Song, Fuchun Wan. Tranquilizing and Allaying Excitement Needling Method Affects BDNF and SYP Expression in Hippocampus. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-09-30. PMID:28761498. |
tranquilizing and allaying excitement needling method affects bdnf and syp expression in hippocampus. |
2020-09-30 |
2023-08-13 |
rat |
| Peng Zheng, Xiaohong Xu, Hongyan Zhao, Tingting Lv, Bailin Song, Fuchun Wan. Tranquilizing and Allaying Excitement Needling Method Affects BDNF and SYP Expression in Hippocampus. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-09-30. PMID:28761498. |
we observed bdnf and syp expression in hippocampus in these three groups. |
2020-09-30 |
2023-08-13 |
rat |
| Peng Zheng, Xiaohong Xu, Hongyan Zhao, Tingting Lv, Bailin Song, Fuchun Wan. Tranquilizing and Allaying Excitement Needling Method Affects BDNF and SYP Expression in Hippocampus. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-09-30. PMID:28761498. |
our study explored the bdnf and syp abnormality in hippocampus caused by sleep deprivation and "tranquilizing and allaying excitement" intervention regulated the abnormal expression of bdnf and syp caused by sleep deprivation on the short run and the long run. |
2020-09-30 |
2023-08-13 |
rat |
| Indira Mendez-David, Jean-Philippe Guilloux, Mariusz Papp, Laurent Tritschler, Elisabeth Mocaer, Alain M Gardier, Sylvie Bretin, Denis J Davi. S 47445 Produces Antidepressant- and Anxiolytic-Like Effects through Neurogenesis Dependent and Independent Mechanisms. Frontiers in pharmacology. vol 8. 2020-09-30. PMID:28769796. |
in a mouse model of genetic ablation of hippocampal neurogenesis (gfap-tk model), neurogenesis dependent/independent effects of chronic s 47445 treatment were tested, as well as bdnf hippocampal expression. |
2020-09-30 |
2023-08-13 |
mouse |
| Indira Mendez-David, Jean-Philippe Guilloux, Mariusz Papp, Laurent Tritschler, Elisabeth Mocaer, Alain M Gardier, Sylvie Bretin, Denis J Davi. S 47445 Produces Antidepressant- and Anxiolytic-Like Effects through Neurogenesis Dependent and Independent Mechanisms. Frontiers in pharmacology. vol 8. 2020-09-30. PMID:28769796. |
the observed increase in hippocampal bdnf levels could be one of the mechanisms of s 47445 responsible for the adult hippocampal neurogenesis increase. |
2020-09-30 |
2023-08-13 |
mouse |
| Hui Zhao, Bingyu Liang, Linjie Yu, Yun X. Anti-depressant-like effects of Jieyu chufan capsules in a mouse model of unpredictable chronic mild stress. Experimental and therapeutic medicine. vol 14. issue 2. 2020-09-30. PMID:28810562. |
in addition, synaptic density in the hippocampus was evaluated and western blot and immunostaining were used to analyze hippocampal expression of postsynaptic density protein-95 (psd95), synaptophysin (syn), cyclic adenosine monophosphate response element binding protein (creb), brain-derived neurotrophic factor (bdnf), akt and glycogen synthase kinase (gsk)-3β as well as their phosphorylated (p) versions. |
2020-09-30 |
2023-08-13 |
mouse |
| Hui Zhao, Bingyu Liang, Linjie Yu, Yun X. Anti-depressant-like effects of Jieyu chufan capsules in a mouse model of unpredictable chronic mild stress. Experimental and therapeutic medicine. vol 14. issue 2. 2020-09-30. PMID:28810562. |
moreover, jycf upregulated the expression of psd95, syn and bdnf and increased phosphorylated akt, creb and gsk-3β in the hippocampus. |
2020-09-30 |
2023-08-13 |
mouse |