| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lin-Lin Liu, Jia-Mei Li, Wen-Jun Su, Bo Wang, Chun-Lei Jian. Sex differences in depressive-like behaviour may relate to imbalance of microglia activation in the hippocampus. Brain, behavior, and immunity. vol 81. 2020-08-04. PMID:31181346. |
afterwards, we observed that the expressions of bdnf and its receptor trkb in hippocampus decreased greater in female compared to male mice when facing stress stimulations. |
2020-08-04 |
2023-08-13 |
mouse |
| Lin-Lin Liu, Jia-Mei Li, Wen-Jun Su, Bo Wang, Chun-Lei Jian. Sex differences in depressive-like behaviour may relate to imbalance of microglia activation in the hippocampus. Brain, behavior, and immunity. vol 81. 2020-08-04. PMID:31181346. |
furthermore, the depressive-like behaviours were correlated to bdnf mrna quantities in both sex mice, and there was also a sex-specific relationship between bdnf and hippocampal microglia-related inflammatory biomarkers. |
2020-08-04 |
2023-08-13 |
mouse |
| Daniel Silva-Peña, Nuria García-Marchena, Francisco Alén, Pedro Araos, Patricia Rivera, Antonio Vargas, María Inmaculada García-Fernández, Ana Isabel Martín-Velasco, María Ángeles Villanúa, Estela Castilla-Ortega, Luis Santín, Francisco Javier Pavón, Antonia Serrano, Gabriel Rubio, Fernando Rodríguez de Fonseca, Juan Suáre. Alcohol-induced cognitive deficits are associated with decreased circulating levels of the neurotrophin BDNF in humans and rats. Addiction biology. vol 24. issue 5. 2020-08-03. PMID:30277635. |
in the ethanol-exposed rats, the plasma levels of bdnf and nt-3 were also decreased, and a negative correlation between hippocampal bdnf mrna levels and recognition memory was found. |
2020-08-03 |
2023-08-13 |
human |
| Daniel Silva-Peña, Nuria García-Marchena, Francisco Alén, Pedro Araos, Patricia Rivera, Antonio Vargas, María Inmaculada García-Fernández, Ana Isabel Martín-Velasco, María Ángeles Villanúa, Estela Castilla-Ortega, Luis Santín, Francisco Javier Pavón, Antonia Serrano, Gabriel Rubio, Fernando Rodríguez de Fonseca, Juan Suáre. Alcohol-induced cognitive deficits are associated with decreased circulating levels of the neurotrophin BDNF in humans and rats. Addiction biology. vol 24. issue 5. 2020-08-03. PMID:30277635. |
the ethanol-exposed rat hippocampus showed a decrease in the mrna levels of neurotrophic (bdnf and ntf-3) and neurogenic (mki67, sox2, dcx, ncam1 and calb1) factors, associated to a deactivation of the neurogenic regulator mitogen-activated protein kinase extracellular signal-regulated kinase. |
2020-08-03 |
2023-08-13 |
human |
| Michaela Shishmanova-Doseva, Katerina Georgieva, Yvetta Koeva, Dora Terzieva, Lyudmil Peyche. Enhancing effect of aerobic training on learning and memory performance in rats after long-term treatment with Lacosamide via BDNF-TrkB signaling pathway. Behavioural brain research. vol 370. 2020-07-30. PMID:31116960. |
the present study assesses the effect of aerobic training on cognitive functions, hippocampal bdnf/trkb ligand receptor system expression and serum levels of bdnf and corticosterone in intact rats after chronic treatment with lacosamide (lcm). |
2020-07-30 |
2023-08-13 |
rat |
| Michaela Shishmanova-Doseva, Katerina Georgieva, Yvetta Koeva, Dora Terzieva, Lyudmil Peyche. Enhancing effect of aerobic training on learning and memory performance in rats after long-term treatment with Lacosamide via BDNF-TrkB signaling pathway. Behavioural brain research. vol 370. 2020-07-30. PMID:31116960. |
aerobic training increased bdnf and trkb hippocampal immunoreactivity. |
2020-07-30 |
2023-08-13 |
rat |
| Bruk Getachew, Liliana Mendieta, Antonei B Csoka, José Aguilera, Yousef Tizab. Antidepressant effects of C-Terminal domain of the heavy chain of tetanus toxin in a rat model of depression. Behavioural brain research. vol 370. 2020-07-30. PMID:31125623. |
concomitant with the 24 h behavioral effects, the levels of hippocampal and frontal cortical bdnf were significantly increased, whereas the levels of tnf-alpha in both these areas were significantly decreased. |
2020-07-30 |
2023-08-13 |
rat |
| Foad Feizolahi, Mohammad-Ali Azarbayjani, Mohammad Nasehi, Maghsoud Peeri, Mohammad-Reza Zarrindas. The combination of swimming and curcumin consumption may improve spatial memory recovery after binge ethanol drinking. Physiology & behavior. vol 207. 2020-07-27. PMID:31071339. |
furthermore, levels of bdnf were measured in hippocampal tissue by doing real time pcr. |
2020-07-27 |
2023-08-13 |
rat |
| Stephen D Ginsberg, Michael H Malek-Ahmadi, Melissa J Alldred, Yinghua Chen, Kewei Chen, Moses V Chao, Scott E Counts, Elliott J Mufso. Brain-derived neurotrophic factor (BDNF) and TrkB hippocampal gene expression are putative predictors of neuritic plaque and neurofibrillary tangle pathology. Neurobiology of disease. vol 132. 2020-07-27. PMID:31349032. |
brain-derived neurotrophic factor (bdnf) and trkb hippocampal gene expression are putative predictors of neuritic plaque and neurofibrillary tangle pathology. |
2020-07-27 |
2023-08-13 |
Not clear |
| Xiao-Ying Lin, Ying Cui, Lei Wang, Wen Che. Chronic exercise buffers the cognitive dysfunction and decreases the susceptibility to seizures in PTZ-treated rats. Epilepsy & behavior : E&B. vol 98. issue Pt A. 2020-07-27. PMID:31377659. |
the levels of synaptic-related proteins including psd95 (postsynaptic density 95), synapsin, glua1, and bdnf (brain-derived neurotrophic factor) were measured to evaluate the hippocampal synaptic plasticity. |
2020-07-27 |
2023-08-13 |
rat |
| Mingxing Li, Xuejiao Sun, Qian Li, Yong Li, Can Luo, Hailong Huang, Jing Chen, Chenzi Gong, Yajie Li, Yifeng Zheng, Song Zhang, Xiaolin Huang, Hong Che. Fucoidan exerts antidepressant-like effects in mice via regulating the stability of surface AMPARs. Biochemical and biophysical research communications. vol 521. issue 2. 2020-07-27. PMID:31668812. |
interestingly, chronic fucoidan administration not only dose-dependently reduced stress-induced depressive-like behaviors in the tst, fst, sucrose preference test (spt), and novelty-suppressed feeding test (nsft), but also alleviated the downregulation of brain-derived neurotrophic factor (bdnf)-dependent synaptic plasticity via inhibiting caspase-1-mediated inflammation in the hippocampus of mice. |
2020-07-27 |
2023-08-13 |
mouse |
| Pedro Afonso, Pasqualino De Luca, Rafael S Carvalho, Luísa Cortes, Paulo Pinheiro, Barbara Oliveiros, Ramiro D Almeida, Miranda Mele, Carlos B Duart. BDNF increases synaptic NMDA receptor abundance by enhancing the local translation of Pyk2 in cultured hippocampal neurons. Science signaling. vol 12. issue 586. 2020-07-24. PMID:31213568. |
bdnf increases synaptic nmda receptor abundance by enhancing the local translation of pyk2 in cultured hippocampal neurons. |
2020-07-24 |
2023-08-13 |
rat |
| Pedro Afonso, Pasqualino De Luca, Rafael S Carvalho, Luísa Cortes, Paulo Pinheiro, Barbara Oliveiros, Ramiro D Almeida, Miranda Mele, Carlos B Duart. BDNF increases synaptic NMDA receptor abundance by enhancing the local translation of Pyk2 in cultured hippocampal neurons. Science signaling. vol 12. issue 586. 2020-07-24. PMID:31213568. |
bdnf induced the synaptic accumulation of glun2b-containing nmda receptors (nmdars) and increased the amplitude of nmdar-mediated miniature excitatory postsynaptic currents (mepscs) in cultured rat hippocampal neurons by a mechanism requiring activation of the protein tyrosine kinase pyk2 and dependent on cellular protein synthesis. |
2020-07-24 |
2023-08-13 |
rat |
| Pedro Afonso, Pasqualino De Luca, Rafael S Carvalho, Luísa Cortes, Paulo Pinheiro, Barbara Oliveiros, Ramiro D Almeida, Miranda Mele, Carlos B Duart. BDNF increases synaptic NMDA receptor abundance by enhancing the local translation of Pyk2 in cultured hippocampal neurons. Science signaling. vol 12. issue 586. 2020-07-24. PMID:31213568. |
furthermore, bdnf increased the local synthesis of pyk2 at the synapse, and the observed increase in pyk2 protein abundance along dendrites of cultured hippocampal neurons was mediated by a mechanism dependent on the ribonucleoprotein hnrnp k, which bound to |
2020-07-24 |
2023-08-13 |
rat |
| Keli Yao, Qin Yang, Yajuan Li, Ting Lan, Hong Yu, Yang Y. MicroRNA-9 mediated the protective effect of ferulic acid on hypoxic-ischemic brain damage in neonatal rats. PloS one. vol 15. issue 5. 2020-07-24. PMID:32470970. |
indeed, the silencing of mir-9 by lna-mir-9 or fa similarly attenuated neuronal damage and cerebral atrophy in the rat hippocampus after hibd, which was consistent with the restored expression levels of brain-derived neurotrophic factor (bdnf). |
2020-07-24 |
2023-08-13 |
rat |
| Maryam Zeraati, Mohsen Enayati, Laya Kafami, Seyed Houtan Shahidi, Ali-Akbar Salar. Gut microbiota depletion from early adolescence alters adult immunological and neurobehavioral responses in a mouse model of multiple sclerosis. Neuropharmacology. vol 157. 2020-07-21. PMID:31247271. |
we measured levels of interferon (ifn)-γ, interleukin (il)-17a and il-10 in serum, and bdnf, il-1β and tumor necrosis factor (tnf)-α) in the hippocampus. |
2020-07-21 |
2023-08-13 |
mouse |
| Maryam Zeraati, Mohsen Enayati, Laya Kafami, Seyed Houtan Shahidi, Ali-Akbar Salar. Gut microbiota depletion from early adolescence alters adult immunological and neurobehavioral responses in a mouse model of multiple sclerosis. Neuropharmacology. vol 157. 2020-07-21. PMID:31247271. |
antibiotic treatment significantly decreased hippocampal bdnf and enhanced learning and memory impairments in eae-induced mice. |
2020-07-21 |
2023-08-13 |
mouse |
| Ali Rashidy-Pour, Kowsar Bavarsad, Hossein Miladi-Gorji, Zahra Seraj, Abbas Ali Vafae. Voluntary exercise and estradiol reverse ovariectomy-induced spatial learning and memory deficits and reduction in hippocampal brain-derived neurotrophic factor in rats. Pharmacology, biochemistry, and behavior. vol 187. 2020-07-21. PMID:31697961. |
this study was designed to investigate the effects of voluntary exercise and estrogen replacement on learning and memory deficits and reduction in hippocampal brain derived neurotrophic factor (bdnf) levels induced by ovariectomy. |
2020-07-21 |
2023-08-13 |
rat |
| Ali Rashidy-Pour, Kowsar Bavarsad, Hossein Miladi-Gorji, Zahra Seraj, Abbas Ali Vafae. Voluntary exercise and estradiol reverse ovariectomy-induced spatial learning and memory deficits and reduction in hippocampal brain-derived neurotrophic factor in rats. Pharmacology, biochemistry, and behavior. vol 187. 2020-07-21. PMID:31697961. |
at the end of the behavioral tests, all animals were decapitated and their hippocampal levels of bdnf were measured. |
2020-07-21 |
2023-08-13 |
rat |
| Ali Rashidy-Pour, Kowsar Bavarsad, Hossein Miladi-Gorji, Zahra Seraj, Abbas Ali Vafae. Voluntary exercise and estradiol reverse ovariectomy-induced spatial learning and memory deficits and reduction in hippocampal brain-derived neurotrophic factor in rats. Pharmacology, biochemistry, and behavior. vol 187. 2020-07-21. PMID:31697961. |
ovariectomy impaired spatial learning and memory and reduced hippocampal bdnf levels. |
2020-07-21 |
2023-08-13 |
rat |