| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yan Lu, Xiuxia Wang, Jiaojiao Feng, Tao Xie, Peipei Si, Weiping Wan. Neuroprotective effect of astaxanthin on newborn rats exposed to prenatal maternal seizures. Brain research bulletin. vol 148. 2020-04-17. PMID:30910691. |
prenatal astaxanthin administration ameliorated neuronal lesions, decreased oxidative stress and induced the expression of camp response element-binding protein (creb) and brain-derived neurotrophic factor (bdnf) in the hippocampus of pups. |
2020-04-17 |
2023-08-13 |
rat |
| Monika Kapoor, Sheetal Sharma, Rajat Sandhir, Bimla Nehr. Temporal changes in physiological and molecular markers in various brain regions following transient global ischemia in rats. Molecular biology reports. vol 46. issue 6. 2020-04-15. PMID:31576510. |
increased expressions of various pro-inflammatory cytokines and a decline in bdnf levels in hippocampal regions on 7th day post ischemia, suggesting their role in its pathogenesis. |
2020-04-15 |
2023-08-13 |
rat |
| Monika Kapoor, Sheetal Sharma, Rajat Sandhir, Bimla Nehr. Temporal changes in physiological and molecular markers in various brain regions following transient global ischemia in rats. Molecular biology reports. vol 46. issue 6. 2020-04-15. PMID:31576510. |
the restoration of bdnf and neurotransmitter levels along with significant decline in inflammatory cytokine levels 14th day onwards following ischemia in hippocampus suggested poststroke recovery. |
2020-04-15 |
2023-08-13 |
rat |
| Monika Kapoor, Sheetal Sharma, Rajat Sandhir, Bimla Nehr. Temporal changes in physiological and molecular markers in various brain regions following transient global ischemia in rats. Molecular biology reports. vol 46. issue 6. 2020-04-15. PMID:31576510. |
cortical regions of the ischemic brains were severely affected while hippocampal regions showed significant poststroke recovery, which might attributed to the normalization of bdnf and pro-inflammatory cytokine levels. |
2020-04-15 |
2023-08-13 |
rat |
| Paloma González-Rodríguez, Irene F Ugidos, Diego Pérez-Rodríguez, Berta Anuncibay-Soto, María Santos-Galdiano, Enrique Font-Belmonte, José Manuel Gonzalo-Orden, Arsenio Fernández-Lópe. Brain-derived neurotrophic factor alleviates the oxidative stress induced by oxygen and glucose deprivation in an ex vivo brain slice model. Journal of cellular physiology. vol 234. issue 6. 2020-04-13. PMID:30317637. |
ogd/rl increased a number of parameters mirroring oxidative stress in the hippocampus that were reduced by the bdnf presence. |
2020-04-13 |
2023-08-13 |
rat |
| Paloma González-Rodríguez, Irene F Ugidos, Diego Pérez-Rodríguez, Berta Anuncibay-Soto, María Santos-Galdiano, Enrique Font-Belmonte, José Manuel Gonzalo-Orden, Arsenio Fernández-Lópe. Brain-derived neurotrophic factor alleviates the oxidative stress induced by oxygen and glucose deprivation in an ex vivo brain slice model. Journal of cellular physiology. vol 234. issue 6. 2020-04-13. PMID:30317637. |
bdnf also reduced the ogd/rl-increased activity in a number of antioxidant enzymes in the hippocampus but no effects were observed in the cerebral cortex. |
2020-04-13 |
2023-08-13 |
rat |
| Dalibor Stajic, Dragica Selakovic, Nemanja Jovicic, Jovana Joksimovic, Nebojsa Arsenijevic, Miodrag L Lukic, Gvozden Rosi. The role of galectin-3 in modulation of anxiety state level in mice. Brain, behavior, and immunity. vol 78. 2020-04-13. PMID:30682502. |
gal-3 deficiency was also accompanied with lower brain-derived neurotrophic factor (bdnf) relative gene expression and immunoreactivity in hippocampus (predominantly in ca1 region). |
2020-04-13 |
2023-08-13 |
mouse |
| Dalibor Stajic, Dragica Selakovic, Nemanja Jovicic, Jovana Joksimovic, Nebojsa Arsenijevic, Miodrag L Lukic, Gvozden Rosi. The role of galectin-3 in modulation of anxiety state level in mice. Brain, behavior, and immunity. vol 78. 2020-04-13. PMID:30682502. |
the anxiogenic effect of acute neuroinflammation was accompanied with increased hippocampal il-6, tnf-α and tlr4 gene expression, as well as decreased gene and immunohistochemical bdnf expression in hippocampus, with significant decline in gaba-ar2s in wild type (wt) mice in comparison to basal conditions. |
2020-04-13 |
2023-08-13 |
mouse |
| Dalibor Stajic, Dragica Selakovic, Nemanja Jovicic, Jovana Joksimovic, Nebojsa Arsenijevic, Miodrag L Lukic, Gvozden Rosi. The role of galectin-3 in modulation of anxiety state level in mice. Brain, behavior, and immunity. vol 78. 2020-04-13. PMID:30682502. |
gal-3 gene deletion prevented the increase in il-6, the decline in bdnf gene expression and immunoreactivity, and reduction in hippocampal gaba-ar2s, and therefore attenuated the anxiogenic effect of neuroinflammation. |
2020-04-13 |
2023-08-13 |
mouse |
| Dalibor Stajic, Dragica Selakovic, Nemanja Jovicic, Jovana Joksimovic, Nebojsa Arsenijevic, Miodrag L Lukic, Gvozden Rosi. The role of galectin-3 in modulation of anxiety state level in mice. Brain, behavior, and immunity. vol 78. 2020-04-13. PMID:30682502. |
in summary, our data demonstrate that apparently opposite effects of gal-3 deficiency on anxiety levels (anxiogenic effect under basal conditions and anxiolytic action during neuroinflammation) seem to be related to the shift in il-6, tnf-α and hippocampal bdnf. |
2020-04-13 |
2023-08-13 |
mouse |
| Xiuqin Li, Hongze Wang, Qingnian Chen, Zhiqin Li, Chao Liu, Shengnan Yin, Zhengchen Yo. Felbamate produces antidepressant-like actions in the chronic unpredictable mild stress and chronic social defeat stress models of depression. Fundamental & clinical pharmacology. vol 33. issue 6. 2020-04-13. PMID:30951217. |
the changes in the hippocampal brain-derived neurotrophic factor (bdnf) signaling cascade after chronic stress and felbamate treatment were also examined. |
2020-04-13 |
2023-08-13 |
mouse |
| Xiuqin Li, Hongze Wang, Qingnian Chen, Zhiqin Li, Chao Liu, Shengnan Yin, Zhengchen Yo. Felbamate produces antidepressant-like actions in the chronic unpredictable mild stress and chronic social defeat stress models of depression. Fundamental & clinical pharmacology. vol 33. issue 6. 2020-04-13. PMID:30951217. |
moreover, felbamate administration fully restored the decreased hippocampal bdnf signaling pathway in both the cums-stressed and csds-stressed mice. |
2020-04-13 |
2023-08-13 |
mouse |
| Xiuqin Li, Hongze Wang, Qingnian Chen, Zhiqin Li, Chao Liu, Shengnan Yin, Zhengchen Yo. Felbamate produces antidepressant-like actions in the chronic unpredictable mild stress and chronic social defeat stress models of depression. Fundamental & clinical pharmacology. vol 33. issue 6. 2020-04-13. PMID:30951217. |
collectively, felbamate has antidepressant-like actions in mice involving the hippocampal bdnf system. |
2020-04-13 |
2023-08-13 |
mouse |
| Zhenggang Guo, Feng Zhao, Ye Wang, Ye Wang, Miaomiao Geng, Yilei Zhang, Qingxia Ma, Xiuzheng X. Sevoflurane Exerts an Anti-depressive Action by Blocking the HMGB1/TLR4 Pathway in Unpredictable Chronic Mild Stress Rats. Journal of molecular neuroscience : MN. vol 69. issue 4. 2020-04-13. PMID:31368063. |
an elisa was performed to detect the levels of brain-derived neurotrophic factor (bdnf) and inflammatory cytokines in the hippocampus of the rats. |
2020-04-13 |
2023-08-13 |
rat |
| Xiao-Yan Liu, Dan Liu, Guo-Peng Lin, Yi-Jing Wu, Lu-Ying Gao, Chao Ai, Yi-Fan Huang, Ming-Fu Wang, Hesham R El-Seedi, Xin-Hua Chen, Chao Zha. Anti-ageing and antioxidant effects of sulfate oligosaccharides from green algae Ulva lactuca and Enteromorpha prolifera in SAMP8 mice. International journal of biological macromolecules. vol 139. 2020-04-08. PMID:31377292. |
after ulo and epo treatment, the levels of inflammatory factors, including ifn-γ, tnf-α, and il-6, decreased; the bdnf and chat levels increased; and hippocampal neurons were protected. |
2020-04-08 |
2023-08-13 |
mouse |
| Mehdi Eivani, Sakineh Alijanpour, Ehsan Arefian, Ameneh Rezayo. Corticolimbic analysis of microRNAs and protein expressions in scopolamine-induced memory loss under stress. Neurobiology of learning and memory. vol 164. 2020-04-08. PMID:31400468. |
the expressions of mir-1, mir-10 and mir-26 and also the levels of p-creb, creb, c-fos and bdnf in the prefrontal cortex (pfc), the hippocampus and the amygdala were evaluated using rt-qpcr and western blotting techniques. |
2020-04-08 |
2023-08-13 |
rat |
| Mehdi Eivani, Sakineh Alijanpour, Ehsan Arefian, Ameneh Rezayo. Corticolimbic analysis of microRNAs and protein expressions in scopolamine-induced memory loss under stress. Neurobiology of learning and memory. vol 164. 2020-04-08. PMID:31400468. |
memory formation increased bdnf, c-fos and p-creb/creb in the pfc, the hippocampus and the amygdala. |
2020-04-08 |
2023-08-13 |
rat |
| D Ozbeyli, A Aykac, N Alaca, A N Hazar-Yavuz, N Ozkan, G Sene. Protective effects of vortioxetine in predator scent stress model of post-traumatic stress disorder in rats: role on neuroplasticity and apoptosis. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 70. issue 4. 2020-04-07. PMID:31642818. |
the b-cell lymphoma (bcl-2)/bcl-2-associated x protein (bax) ratio, brain-derived neurotrophic factor (bdnf), caspase-3 and -9 expressions were detected using western blotting in the amygdaloid complex, hippocampus, and frontal cortex. |
2020-04-07 |
2023-08-13 |
rat |
| D Ozbeyli, A Aykac, N Alaca, A N Hazar-Yavuz, N Ozkan, G Sene. Protective effects of vortioxetine in predator scent stress model of post-traumatic stress disorder in rats: role on neuroplasticity and apoptosis. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 70. issue 4. 2020-04-07. PMID:31642818. |
decreased bcl-2/bax ratio and bdnf level and increased caspase-3 and -9 expressions in the stress group, improved with vrx in the amygdala, and hippocampus. |
2020-04-07 |
2023-08-13 |
rat |
| Yihang Zhao, Qianxu Wang, Mengzhen Jia, Shangchen Fu, Junru Pan, Chuanqi Chu, Xiaoning Liu, Xuebo Liu, Zhigang Li. (+)-Sesamin attenuates chronic unpredictable mild stress-induced depressive-like behaviors and memory deficits via suppression of neuroinflammation. The Journal of nutritional biochemistry. vol 64. 2020-04-06. PMID:30445417. |
consistently, sesamin also enhanced synapse ultrastructure and improved expressions of psd-95 in stressed mice hippocampus with improving neurotrophic factors expression including bdnf and nt3. |
2020-04-06 |
2023-08-13 |
mouse |