| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael J Chen, Amelia A Russo-Neustad. Exercise activates the phosphatidylinositol 3-kinase pathway. Brain research. Molecular brain research. vol 135. issue 1-2. 2005-07-25. PMID:15857681. |
in young male sprague-dawley rats, we examined the effects of 2 weeks of daily voluntary wheel-running activity and/or tranylcypromine (n = 7 per group) on the levels of the active forms of protein-dependent kinase-1 (pdk-1), pi-3 kinase, phospho-thr308-akt, phospho-ser473-akt, and phospho-glycogen synthase kinase-3beta (gsk3beta; inactive form), as well as bdnf, activated creb, and the phospho-trk receptor, in the rat hippocampus, and compared these with sedentary saline-treated controls. |
2005-07-25 |
2023-08-12 |
rat |
| Syed I A Zaidi, Anjum Jafri, Toye Doggett, Musa A Haxhi. Airway-related vagal preganglionic neurons express brain-derived neurotrophic factor and TrkB receptors: implications for neuronal plasticity. Brain research. vol 1044. issue 2. 2005-07-18. PMID:15885212. |
in addition, brain tissue from the rna region contained measurable amounts of bdnf that were comparable to the hippocampal region of the brain. |
2005-07-18 |
2023-08-12 |
Not clear |
| Mia H Greisen, C Anthony Altar, Tom G Bolwig, Richard Whitehead, Gitta Wörtwei. Increased adult hippocampal brain-derived neurotrophic factor and normal levels of neurogenesis in maternal separation rats. Journal of neuroscience research. vol 79. issue 6. 2005-07-15. PMID:15690366. |
in the present study, a highly significant increase in hippocampal bdnf protein concentration was found in adult rats that as neonates had been subjected to 180 min of daily separation compared with handled rats separated for 15 min daily. |
2005-07-15 |
2023-08-12 |
rat |
| Mia H Greisen, C Anthony Altar, Tom G Bolwig, Richard Whitehead, Gitta Wörtwei. Increased adult hippocampal brain-derived neurotrophic factor and normal levels of neurogenesis in maternal separation rats. Journal of neuroscience research. vol 79. issue 6. 2005-07-15. PMID:15690366. |
expression of bdnf mrna in the ca1, ca3, or dentate gyrus of the hippocampus or in the paraventricular hypothalamic nucleus was not affected by maternal separation. |
2005-07-15 |
2023-08-12 |
rat |
| Mia H Greisen, C Anthony Altar, Tom G Bolwig, Richard Whitehead, Gitta Wörtwei. Increased adult hippocampal brain-derived neurotrophic factor and normal levels of neurogenesis in maternal separation rats. Journal of neuroscience research. vol 79. issue 6. 2005-07-15. PMID:15690366. |
all animals displayed similar behavioral patterns in a forced-swim paradigm, which did not affect bdnf protein concentration in the hippocampus or hypothalamus. |
2005-07-15 |
2023-08-12 |
rat |
| Mia H Greisen, C Anthony Altar, Tom G Bolwig, Richard Whitehead, Gitta Wörtwei. Increased adult hippocampal brain-derived neurotrophic factor and normal levels of neurogenesis in maternal separation rats. Journal of neuroscience research. vol 79. issue 6. 2005-07-15. PMID:15690366. |
insofar as bdnf can stimulate neurogenesis and repair, we propose that the elevated hippocampal protein concentration found in maternally deprived rats might be a compensatory reaction to separation during the neonatal period, maintaining adult neurogenesis at levels equal to those of the handled rats. |
2005-07-15 |
2023-08-12 |
rat |
| Mei-Jiang Feng, Shu-E Yan, Qing-Shan Ya. Effects of prenatal alcohol exposure on brain-derived neurotrophic factor and its receptor tyrosine kinase B in offspring. Brain research. vol 1042. issue 2. 2005-07-15. PMID:15854584. |
however, administration of alcohol at the dose of 3 g/kg/day markedly reduced levels of bdnf protein and mrna in the cortex and hippocampus of offspring. |
2005-07-15 |
2023-08-12 |
rat |
| Hyemyung Seo, Ole Isacso. Abnormal APP, cholinergic and cognitive function in Ts65Dn Down's model mice. Experimental neurology. vol 193. issue 2. 2005-07-15. PMID:15869949. |
at this age, both ts65dn mice and their lm abnormally responded to cholinergic muscarinic m1 agonist treatment in terms of hippocampal app, nerve growth factor (ngf), and brain-derived neurotrophic factor (bdnf) levels compared to young adult c57bl/6 mice. |
2005-07-15 |
2023-08-12 |
mouse |
| Jung Lee, Hiroaki Fukumoto, Jennifer Orne, Jochen Klucken, Susan Raju, Charles R Vanderburg, Michael C Irizarry, Bradley T Hyman, Martin Ingelsso. Decreased levels of BDNF protein in Alzheimer temporal cortex are independent of BDNF polymorphisms. Experimental neurology. vol 194. issue 1. 2005-07-15. PMID:15899246. |
levels of brain-derived neurotrophic factor (bdnf) are reduced in specific brain regions in alzheimer's disease (ad) and bdnf gene polymorphisms have been suggested to influence ad risk, hippocampal function, and memory. |
2005-07-15 |
2023-08-12 |
human |
| O L Gobbo, S M O'Mar. Exercise, but not environmental enrichment, improves learning after kainic acid-induced hippocampal neurodegeneration in association with an increase in brain-derived neurotrophic factor. Behavioural brain research. vol 159. issue 1. 2005-07-12. PMID:15794993. |
furthermore, both exercise and enriched environment did not protect against neuron loss in ca1, ca2 and ca3 areas of the hippocampus, despite a substantial increase in brain-derived neutrophic factor (bdnf) levels in dentate gyrus of the exercise and ka-treated animals. |
2005-07-12 |
2023-08-12 |
Not clear |
| Shingo Miyata, Yasutake Mori, Tatsuji Fujiwara, Kensuke Ikenaka, Shinsuke Matsuzaki, Kayoko Oono, Taiichi Katayama, Masaya Tohyam. Local protein synthesis by BDNF is potentiated in hippocampal neurons exposed to ephrins. Brain research. Molecular brain research. vol 134. issue 2. 2005-07-05. PMID:15836928. |
local protein synthesis by bdnf is potentiated in hippocampal neurons exposed to ephrins. |
2005-07-05 |
2023-08-12 |
Not clear |
| Shingo Miyata, Yasutake Mori, Tatsuji Fujiwara, Kensuke Ikenaka, Shinsuke Matsuzaki, Kayoko Oono, Taiichi Katayama, Masaya Tohyam. Local protein synthesis by BDNF is potentiated in hippocampal neurons exposed to ephrins. Brain research. Molecular brain research. vol 134. issue 2. 2005-07-05. PMID:15836928. |
to solve the problem, we applied fluorescence resonance energy transfer (fret) technique to in situ detection of the assembly and disassembly cycle among a pair of translation initiation factors [eukaryotic initiation factors (eifs)], thereby showing that bdnf and ephrin could potentiate local protein synthesis in the dendrites of hippocampal neurons. |
2005-07-05 |
2023-08-12 |
Not clear |
| Cheryl A Frye, Madeline E Rhodes, Bruce Dude. Estradiol to aged female or male mice improves learning in inhibitory avoidance and water maze tasks. Brain research. vol 1036. issue 1-2. 2005-06-16. PMID:15725406. |
following behavioral testing, effects of 1 or 24 h of e2 exposure on hippocampal levels of e2 and brain-derived neurotrophic factor (bdnf) were examined. |
2005-06-16 |
2023-08-12 |
mouse |
| Cheryl A Frye, Madeline E Rhodes, Bruce Dude. Estradiol to aged female or male mice improves learning in inhibitory avoidance and water maze tasks. Brain research. vol 1036. issue 1-2. 2005-06-16. PMID:15725406. |
bdnf levels in the hippocampus were decreased following 1 h of e2 exposure compared to vehicle. |
2005-06-16 |
2023-08-12 |
mouse |
| b' Francesco Angelucci, Luigi Aloe, Angela Iannitelli, Susanne H M Gruber, Aleksander A Math\\xc3\\xa. Effect of chronic olanzapine treatment on nerve growth factor and brain-derived neurotrophic factor in the rat brain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 15. issue 3. 2005-06-08. PMID:15820421.' |
in contrast, olanzapine decreased bdnf in the hippocampus and frontal cortex. |
2005-06-08 |
2023-08-12 |
rat |
| Holger Rosenbrock, Eliza Koros, Anita Bloching, Jana Podhorna, Franco Borsin. Effect of chronic intermittent restraint stress on hippocampal expression of marker proteins for synaptic plasticity and progenitor cell proliferation in rats. Brain research. vol 1040. issue 1-2. 2005-06-07. PMID:15804426. |
chronic restraint stress may change hippocampal mrna levels of markers for synaptic plasticity such as synaptophysin, growth-associated protein 43 (gap-43), and brain-derived neurotrophic factor (bdnf). |
2005-06-07 |
2023-08-12 |
rat |
| Barbara Viviani, Stefano Bartesaghi, Emanuela Corsini, Pia Villa, Pietro Ghezzi, Angela Garau, Corrado L Galli, Marina Marinovic. Erythropoietin protects primary hippocampal neurons increasing the expression of brain-derived neurotrophic factor. Journal of neurochemistry. vol 93. issue 2. 2005-05-20. PMID:15816864. |
using primary cultures of rat hippocampal neurons, we investigated whether erythropoietin could mediate neuroprotection favouring the transcription of brain-derived neurotrophic factor (bdnf). |
2005-05-20 |
2023-08-12 |
mouse |
| F Gomez-Pinilla, S Vaynma. A "deficient environment" in prenatal life may compromise systems important for cognitive function by affecting BDNF in the hippocampus. Experimental neurology. vol 192. issue 2. 2005-05-16. PMID:15755541. |
a "deficient environment" in prenatal life may compromise systems important for cognitive function by affecting bdnf in the hippocampus. |
2005-05-16 |
2023-08-12 |
Not clear |
| Sandra Dieni, Sandra Ree. BDNF and TrkB protein expression is altered in the fetal hippocampus but not cerebellum after chronic prenatal compromise. Experimental neurology. vol 192. issue 2. 2005-05-16. PMID:15755544. |
bdnf and trkb protein expression is altered in the fetal hippocampus but not cerebellum after chronic prenatal compromise. |
2005-05-16 |
2023-08-12 |
Not clear |
| Sandra Dieni, Sandra Ree. BDNF and TrkB protein expression is altered in the fetal hippocampus but not cerebellum after chronic prenatal compromise. Experimental neurology. vol 192. issue 2. 2005-05-16. PMID:15755544. |
this study examines the effects of a chronic prenatal insult on both the expression of brain-derived neurotrophic factor (bdnf) and trkb proteins and the structural development of the fetal hippocampus and cerebellum. |
2005-05-16 |
2023-08-12 |
Not clear |