| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amy L Allen, Kenneth E McCarso. Estrogen increases nociception-evoked brain-derived neurotrophic factor gene expression in the female rat. Neuroendocrinology. vol 81. issue 3. 2005-11-15. PMID:16020928. |
results demonstrated that estrogen replacement increased bdnf mrna levels in the hippocampus, cortex and spinal cord. |
2005-11-15 |
2023-08-12 |
rat |
| Amy L Allen, Kenneth E McCarso. Estrogen increases nociception-evoked brain-derived neurotrophic factor gene expression in the female rat. Neuroendocrinology. vol 81. issue 3. 2005-11-15. PMID:16020928. |
cortical bdnf mrna levels were significantly decreased by nociception, in the hippocampus this decrease was only evident in estrogen-treated rats. |
2005-11-15 |
2023-08-12 |
rat |
| R D Almeida, B J Manadas, C V Melo, J R Gomes, C S Mendes, M M Grãos, R F Carvalho, A P Carvalho, C B Duart. Neuroprotection by BDNF against glutamate-induced apoptotic cell death is mediated by ERK and PI3-kinase pathways. Cell death and differentiation. vol 12. issue 10. 2005-11-10. PMID:15905876. |
moreover, incubation of hippocampal neurons with bdnf, for 24 h, increased bcl-2 protein levels. |
2005-11-10 |
2023-08-12 |
Not clear |
| R D Almeida, B J Manadas, C V Melo, J R Gomes, C S Mendes, M M Grãos, R F Carvalho, A P Carvalho, C B Duart. Neuroprotection by BDNF against glutamate-induced apoptotic cell death is mediated by ERK and PI3-kinase pathways. Cell death and differentiation. vol 12. issue 10. 2005-11-10. PMID:15905876. |
the results indicate that the protective effect of bdnf in hippocampal neurons against glutamate toxicity is mediated by the pi3-k and the ras/mapk signaling pathways, and involves a long-term change in protein synthesis. |
2005-11-10 |
2023-08-12 |
Not clear |
| Zhong Chen, Haiyun Xu, Samson Haimano, Xiaokun Li, Xin-Min L. Quetiapine and venlafaxine synergically regulate heme oxygenase-2 protein expression in the hippocampus of stressed rats. Neuroscience letters. vol 389. issue 3. 2005-11-07. PMID:16115734. |
in previous studies, these two drugs have been shown to prevent or protect against the stress-induced decrease in hippocampal neurogenesis and bdnf expression. |
2005-11-07 |
2023-08-12 |
rat |
| Jagadish Ulloor, Subimal Datt. Spatio-temporal activation of cyclic AMP response element-binding protein, activity-regulated cytoskeletal-associated protein and brain-derived nerve growth factor: a mechanism for pontine-wave generator activation-dependent two-way active-avoidance memory processing in the rat. Journal of neurochemistry. vol 95. issue 2. 2005-11-02. PMID:16190868. |
learning training also increased synthesis of brain-derived nerve growth factor (bdnf) in the occipital cortex, amygdala and dorsal hippocampus at different time intervals. |
2005-11-02 |
2023-08-12 |
rat |
| Jagadish Ulloor, Subimal Datt. Spatio-temporal activation of cyclic AMP response element-binding protein, activity-regulated cytoskeletal-associated protein and brain-derived nerve growth factor: a mechanism for pontine-wave generator activation-dependent two-way active-avoidance memory processing in the rat. Journal of neurochemistry. vol 95. issue 2. 2005-11-02. PMID:16190868. |
the results also show that the increase in rapid eye movement sleep p-wave density during the post-training 3-h recording session is positively correlated with the increased levels of phosphorylated creb, bdnf and arc in the dorsal hippocampus. |
2005-11-02 |
2023-08-12 |
rat |
| Shuji Murakami, Hiroki Imbe, Yoshihiro Morikawa, Chiharu Kubo, Emiko Senb. Chronic stress, as well as acute stress, reduces BDNF mRNA expression in the rat hippocampus but less robustly. Neuroscience research. vol 53. issue 2. 2005-11-01. PMID:16024125. |
chronic stress, as well as acute stress, reduces bdnf mrna expression in the rat hippocampus but less robustly. |
2005-11-01 |
2023-08-12 |
rat |
| Shuji Murakami, Hiroki Imbe, Yoshihiro Morikawa, Chiharu Kubo, Emiko Senb. Chronic stress, as well as acute stress, reduces BDNF mRNA expression in the rat hippocampus but less robustly. Neuroscience research. vol 53. issue 2. 2005-11-01. PMID:16024125. |
plasma glucocorticoid (gc) and serotonergic projections from the raphe nuclei play major roles in reducing bdnf synthesis in the hippocampus. |
2005-11-01 |
2023-08-12 |
rat |
| Shuji Murakami, Hiroki Imbe, Yoshihiro Morikawa, Chiharu Kubo, Emiko Senb. Chronic stress, as well as acute stress, reduces BDNF mRNA expression in the rat hippocampus but less robustly. Neuroscience research. vol 53. issue 2. 2005-11-01. PMID:16024125. |
in these animals, bdnf mrna levels were significantly decreased in the hippocampus after 6 h of restraint, but the ability of restraint to reduce bdnf synthesis seemed less robust than that seen in acute stress models. |
2005-11-01 |
2023-08-12 |
rat |
| Shuji Murakami, Hiroki Imbe, Yoshihiro Morikawa, Chiharu Kubo, Emiko Senb. Chronic stress, as well as acute stress, reduces BDNF mRNA expression in the rat hippocampus but less robustly. Neuroscience research. vol 53. issue 2. 2005-11-01. PMID:16024125. |
repetitive stress-induced reduction of bdnf may partly contribute to the neuronal atrophy/death and reduction of hippocampal volume observed both in animals and humans suffering chronic stress and/or depression. |
2005-11-01 |
2023-08-12 |
rat |
| Avtandil Nanobashvili, Katherine Jakubs, Merab Kokai. Chronic BDNF deficiency permanently modifies excitatory synapses in the piriform cortex. Journal of neuroscience research. vol 81. issue 5. 2005-11-01. PMID:16035106. |
in support, blockade of bdnf signaling in wild-type hippocampal slices by trkb-igg closely reproduces synaptic alterations observed in bdnf+/- mice. |
2005-11-01 |
2023-08-12 |
mouse |
| Efstathios Garoflos, Antonios Stamatakis, Athanasios Mantelas, Helen Philippidis, Fotini Stylianopoulo. Cellular mechanisms underlying an effect of "early handling" on pCREB and BDNF in the neonatal rat hippocampus. Brain research. vol 1052. issue 2. 2005-10-27. PMID:16024004. |
cellular mechanisms underlying an effect of "early handling" on pcreb and bdnf in the neonatal rat hippocampus. |
2005-10-27 |
2023-08-12 |
rat |
| Efstathios Garoflos, Antonios Stamatakis, Athanasios Mantelas, Helen Philippidis, Fotini Stylianopoulo. Cellular mechanisms underlying an effect of "early handling" on pCREB and BDNF in the neonatal rat hippocampus. Brain research. vol 1052. issue 2. 2005-10-27. PMID:16024004. |
in an effort to address this issue, we employed the model of "early handling", which is known to affect the ability of the adult organism to respond to stressful stimuli, and determined its effects on hippocampal pcreb and bdnf 2, 4, and 8 h later. |
2005-10-27 |
2023-08-12 |
rat |
| Efstathios Garoflos, Antonios Stamatakis, Athanasios Mantelas, Helen Philippidis, Fotini Stylianopoulo. Cellular mechanisms underlying an effect of "early handling" on pCREB and BDNF in the neonatal rat hippocampus. Brain research. vol 1052. issue 2. 2005-10-27. PMID:16024004. |
8 h following "handling" on postnatal day 1, there was an increase in pcreb and bdnf positive cells in the hippocampus, a brain area which is a specific target of "handling". |
2005-10-27 |
2023-08-12 |
rat |
| Ryuta Koyama, Yuji Ikegay. To BDNF or not to BDNF: that is the epileptic hippocampus. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 11. issue 4. 2005-10-19. PMID:16061515. |
to bdnf or not to bdnf: that is the epileptic hippocampus. |
2005-10-19 |
2023-08-12 |
Not clear |
| Ryuta Koyama, Yuji Ikegay. To BDNF or not to BDNF: that is the epileptic hippocampus. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 11. issue 4. 2005-10-19. PMID:16061515. |
in epileptogenesis-related brain areas, including the hippocampus, bdnf is up-regulated in the course of the development of epilepsy and induces a collapse of balanced excitation and inhibition, eventually exerting its epileptogenic effects. |
2005-10-19 |
2023-08-12 |
Not clear |
| Lisa M Rattiner, Michael Davis, Kerry J Ressle. Brain-derived neurotrophic factor in amygdala-dependent learning. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 11. issue 4. 2005-10-19. PMID:16061519. |
long-term potentiation (ltp) within the hippocampus and hippocampally dependent behaviors has been the primary model for examining the role of bdnf in learning and memory. |
2005-10-19 |
2023-08-12 |
Not clear |
| Simone C Tauber, Christine Stadelmann, Annette Spreer, Wolfgang Brück, Roland Nau, Joachim Gerbe. Increased expression of BDNF and proliferation of dentate granule cells after bacterial meningitis. Journal of neuropathology and experimental neurology. vol 64. issue 9. 2005-10-12. PMID:16141791. |
hippocampal bdnf mrna levels were increased 2.4-fold 4 days after infection (p = 0.026). |
2005-10-12 |
2023-08-12 |
mouse |
| Simone C Tauber, Christine Stadelmann, Annette Spreer, Wolfgang Brück, Roland Nau, Joachim Gerbe. Increased expression of BDNF and proliferation of dentate granule cells after bacterial meningitis. Journal of neuropathology and experimental neurology. vol 64. issue 9. 2005-10-12. PMID:16141791. |
bdnf protein was located predominantly in the hippocampal ca3/4 area and the hilus of the dentate gyrus. |
2005-10-12 |
2023-08-12 |
mouse |