| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M C Pardon, R E Roberts, C A Marsden, M Bianchi, M L Latif, M S Duxon, D A Kendal. Social threat and novel cage stress-induced sustained extracellular-regulated kinase1/2 (ERK1/2) phosphorylation but differential modulation of brain-derived neurotrophic factor (BDNF) expression in the hippocampus of NMRI mice. Neuroscience. vol 132. issue 3. 2005-08-30. PMID:15837118. |
the hippocampus showed greater responsiveness to stress as the two stressors increased phospho-erk1/2 and bdnf expression under acute condition. |
2005-08-30 |
2023-08-12 |
mouse |
| M C Pardon, R E Roberts, C A Marsden, M Bianchi, M L Latif, M S Duxon, D A Kendal. Social threat and novel cage stress-induced sustained extracellular-regulated kinase1/2 (ERK1/2) phosphorylation but differential modulation of brain-derived neurotrophic factor (BDNF) expression in the hippocampus of NMRI mice. Neuroscience. vol 132. issue 3. 2005-08-30. PMID:15837118. |
following repeated stress, hyperphosphorylation of erk1/2 was associated with up-regulation of hippocampal bdnf expression in the social threat group but not in mice exposed to novel cage. |
2005-08-30 |
2023-08-12 |
mouse |
| M Silhol, V Bonnichon, F Rage, L Tapia-Arancibi. Age-related changes in brain-derived neurotrophic factor and tyrosine kinase receptor isoforms in the hippocampus and hypothalamus in male rats. Neuroscience. vol 132. issue 3. 2005-08-30. PMID:15837123. |
among neurotrophins (considered as genuine molecular mediators of synaptic plasticity), brain-derived neurotrophic factor (bdnf) exhibits in adult rats, the highest concentrations in the hippocampus and hypothalamus. |
2005-08-30 |
2023-08-12 |
rat |
| M Silhol, V Bonnichon, F Rage, L Tapia-Arancibi. Age-related changes in brain-derived neurotrophic factor and tyrosine kinase receptor isoforms in the hippocampus and hypothalamus in male rats. Neuroscience. vol 132. issue 3. 2005-08-30. PMID:15837123. |
the goal of this study was to examine simultaneously the expression (mrnas and proteins) of bdnf and its three specific receptors, in the hippocampus and hypothalamus throughout lifespan in rats. |
2005-08-30 |
2023-08-12 |
rat |
| M Silhol, V Bonnichon, F Rage, L Tapia-Arancibi. Age-related changes in brain-derived neurotrophic factor and tyrosine kinase receptor isoforms in the hippocampus and hypothalamus in male rats. Neuroscience. vol 132. issue 3. 2005-08-30. PMID:15837123. |
we observed that bdnf essentially increased during the first 2 postnatal weeks in the hippocampus and hypothalamus, with no close correlation to its mrna levels. |
2005-08-30 |
2023-08-12 |
rat |
| M Silhol, V Bonnichon, F Rage, L Tapia-Arancibi. Age-related changes in brain-derived neurotrophic factor and tyrosine kinase receptor isoforms in the hippocampus and hypothalamus in male rats. Neuroscience. vol 132. issue 3. 2005-08-30. PMID:15837123. |
from 2 months old, the bdnf full-length catalytic receptor (trkb.fl) gradually and significantly decreased in the hippocampus and the hypothalamus. |
2005-08-30 |
2023-08-12 |
rat |
| Mark P Mattson, Wenzhen Duan, Ruqian Wan, Zhihong Gu. Prophylactic activation of neuroprotective stress response pathways by dietary and behavioral manipulations. NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics. vol 1. issue 1. 2005-08-25. PMID:15717011. |
dr also stimulates neurogenesis in the hippocampus, and bdnf plays a role in this effect of dr. |
2005-08-25 |
2023-08-12 |
mouse |
| L Willis, E M Quintero, M Nelson, A Ch Granhol. Regulation of trophic factor expression by innervating target regions in intraocular double transplants. Cell transplantation. vol 14. issue 1. 2005-08-23. PMID:15789659. |
transplantation to the anterior chamber of the eye increased the expression of bdnf in the hippocampal but not the brain stem tissue, compared with levels observed in fetal and adult rats in vivo. |
2005-08-23 |
2023-08-12 |
rat |
| L Willis, E M Quintero, M Nelson, A Ch Granhol. Regulation of trophic factor expression by innervating target regions in intraocular double transplants. Cell transplantation. vol 14. issue 1. 2005-08-23. PMID:15789659. |
in addition, double grafting with hippocampal tissue more than tripled bdnf levels in brain stem grafts and doubled bdnf levels in the hippocampal portion of double grafts compared with hippocampal single grafts. |
2005-08-23 |
2023-08-12 |
rat |
| L Willis, E M Quintero, M Nelson, A Ch Granhol. Regulation of trophic factor expression by innervating target regions in intraocular double transplants. Cell transplantation. vol 14. issue 1. 2005-08-23. PMID:15789659. |
triple grafts containing basal forebrain, hippocampus, and brain stem lc tissue increased brain stem and hippocampal bdnf levels even further. |
2005-08-23 |
2023-08-12 |
rat |
| L Willis, E M Quintero, M Nelson, A Ch Granhol. Regulation of trophic factor expression by innervating target regions in intraocular double transplants. Cell transplantation. vol 14. issue 1. 2005-08-23. PMID:15789659. |
colchicine treatment of lc-hippocampal double grafts gave rise to a significant decrease in hippocampal bdnf levels to levels seen in single hippocampal grafts, while only a partial reduction of bdnf levels was seen in the brain stem portion of the same double grafts treated with colchicine. |
2005-08-23 |
2023-08-12 |
rat |
| L Willis, E M Quintero, M Nelson, A Ch Granhol. Regulation of trophic factor expression by innervating target regions in intraocular double transplants. Cell transplantation. vol 14. issue 1. 2005-08-23. PMID:15789659. |
the findings suggest that an appropriate hippocampal innervation or contact with its target tissues is essential for regulation of bdnf expression in the brain stem, and that retrograde transport of bdnf can occur between double grafted fetal tissues in oculo. |
2005-08-23 |
2023-08-12 |
rat |
| Sophie Pezet, Marzia Malcangi. Brain-derived neurotrophic factor as a drug target for CNS disorders. Expert opinion on therapeutic targets. vol 8. issue 5. 2005-08-22. PMID:15469390. |
in adulthood, bdnf can modulate neuronal synaptic strength and has been implicated in hippocampal mechanisms of learning and memory and spinal mechanisms for pain. |
2005-08-22 |
2023-08-12 |
Not clear |
| Marco Fiore, Tiziana Amendola, Viviana Triaca, Enrico Alleva, Luigi Alo. Fighting in the aged male mouse increases the expression of TrkA and TrkB in the subventricular zone and in the hippocampus. Behavioural brain research. vol 157. issue 2. 2005-08-04. PMID:15639186. |
we found that the condition of subordination enhances the level of ngf in the subventricular zone and hippocampus whereas dominance elevates brain derived neurotrophic factor (bdnf). |
2005-08-04 |
2023-08-12 |
mouse |
| Félicien Karege, Geneviève Vaudan, Michèle Schwald, Nader Perroud, Romano La Harp. Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs. Brain research. Molecular brain research. vol 136. issue 1-2. 2005-08-02. PMID:15893584. |
results indicated a significant decrease in bdnf and nt-3 levels in the hippocampus and pfc (only bdnf) but not in the entorhinal cortex, of suicide victims who were drug-free compared with non-suicide controls. |
2005-08-02 |
2023-08-12 |
human |
| Tsuyoshi Ando, Norio Takagi, Keiko Takagi, Tomoyuki Kago, Satoshi Take. Effects of nefiracetam on the levels of brain-derived neurotrophic factor and synapsin I mRNA and protein in the hippocampus of microsphere-embolized rats. European journal of pharmacology. vol 507. issue 1-3. 2005-07-25. PMID:15659294. |
the purpose of the present study was to determine whether nefiracetam has an effect on the expression of brain-derived neurotrophic factor (bdnf) and synapsin i mrnas that are believed to be produced via creb, and the alteration in their protein contents in the hippocampus after cerebral ischemia. |
2005-07-25 |
2023-08-12 |
rat |
| Tsuyoshi Ando, Norio Takagi, Keiko Takagi, Tomoyuki Kago, Satoshi Take. Effects of nefiracetam on the levels of brain-derived neurotrophic factor and synapsin I mRNA and protein in the hippocampus of microsphere-embolized rats. European journal of pharmacology. vol 507. issue 1-3. 2005-07-25. PMID:15659294. |
microsphere-embolized rats on day 5 showed decreases in bdnf and synapsin i mrna levels and their protein contents in the ipsilateral hippocampus. |
2005-07-25 |
2023-08-12 |
rat |
| Takao Hirai, Hideo Taniura, Yasuaki Goto, Keisuke Tamaki, Hirotaka Oikawa, Yuki Kambe, Masato Ogura, Yu Ohno, Takeshi Takarada, Yukio Yoned. Counteraction by repetitive daily exposure to static magnetism against sustained blockade of N-methyl-D-aspartate receptor channels in cultured rat hippocampal neurons. Journal of neuroscience research. vol 80. issue 4. 2005-07-25. PMID:15846781. |
in rat hippocampal neurons cultured with the antagonist for n-methyl-d-aspartate (nmda) receptors dizocilpine (mk-801) for 8 days in vitro (div), a significant decrease was seen in the expression of microtubule-associated protein-2 (map-2) as well as mrna for both brain-derived neurotrophic factor (bdnf) and growth-associated protein-43 (gap-43), in addition to decreased viability. |
2005-07-25 |
2023-08-12 |
rat |
| Peter S Vosler, Eric S Logue, Melissa J Repine, Clifton W Callawa. Delayed hypothermia preferentially increases expression of brain-derived neurotrophic factor exon III in rat hippocampus after asphyxial cardiac arrest. Brain research. Molecular brain research. vol 135. issue 1-2. 2005-07-25. PMID:15857665. |
this study examined whether these different bdnf transcripts are differentially affected by cardiac arrest and by therapeutic hypothermia in rat hippocampus using a reverse transcription and pcr-based method. |
2005-07-25 |
2023-08-12 |
rat |
| Michael J Chen, Amelia A Russo-Neustad. Exercise activates the phosphatidylinositol 3-kinase pathway. Brain research. Molecular brain research. vol 135. issue 1-2. 2005-07-25. PMID:15857681. |
voluntary physical exercise in rats also robustly and rapidly up-regulates hippocampal brain-derived neurotrophic factor (bdnf) mrna levels, which are potentiated following a regimen of chronic antidepressant treatment. |
2005-07-25 |
2023-08-12 |
rat |