| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stephanie Ridder, Sabine Chourbaji, Rainer Hellweg, Alexandre Urani, Christiane Zacher, Wolfgang Schmid, Mathias Zink, Heide Hörtnagl, Herta Flor, Fritz A Henn, Günther Schütz, Peter Gas. Mice with genetically altered glucocorticoid receptor expression show altered sensitivity for stress-induced depressive reactions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 26. 2006-02-14. PMID:15987954. |
as a first potential molecular correlate for such changes, we identified a downregulation of bdnf protein content in the hippocampus of gr+/- mice, which is in agreement with the so-called neurotrophin hypothesis of depression. |
2006-02-14 |
2023-08-12 |
mouse |
| Lisandro Laurino, Xiaoxin X Wang, Becky A de la Houssaye, Lucas Sosa, Sebastian Dupraz, Alfredo Cáceres, Karl H Pfenninger, Santiago Quirog. PI3K activation by IGF-1 is essential for the regulation of membrane expansion at the nerve growth cone. Journal of cell science. vol 118. issue Pt 16. 2006-01-24. PMID:16046480. |
to begin elucidating the signaling pathway by which exocytosis of the plasmalemmal precursor is regulated, we studied activation of the irs/pi3k/akt pathway in isolated growth cones and hippocampal neurons in culture stimulated with igf-1 or bdnf. |
2006-01-24 |
2023-08-12 |
Not clear |
| Mariana Alonso, Pedro Bekinschtein, Martín Cammarota, Monica R M Vianna, Iván Izquierdo, Jorge H Medin. Endogenous BDNF is required for long-term memory formation in the rat parietal cortex. Learning & memory (Cold Spring Harbor, N.Y.). vol 12. issue 5. 2006-01-23. PMID:16204202. |
brain-derived neurotrophic factor (bdnf) modulates both short-term synaptic function and activity-dependent synaptic plasticity in hippocampal and cortical neurons. |
2006-01-23 |
2023-08-12 |
human |
| Mariana Alonso, Pedro Bekinschtein, Martín Cammarota, Monica R M Vianna, Iván Izquierdo, Jorge H Medin. Endogenous BDNF is required for long-term memory formation in the rat parietal cortex. Learning & memory (Cold Spring Harbor, N.Y.). vol 12. issue 5. 2006-01-23. PMID:16204202. |
we have recently demonstrated that endogenous bdnf in the hippocampus is involved in memory formation. |
2006-01-23 |
2023-08-12 |
human |
| Haiyan Li, Clarissa L Waites, Roland G Staal, Yuriy Dobryy, Jeanna Park, David L Sulzer, Robert H Edward. Sorting of vesicular monoamine transporter 2 to the regulated secretory pathway confers the somatodendritic exocytosis of monoamines. Neuron. vol 48. issue 4. 2006-01-18. PMID:16301178. |
although hippocampal neurons do not express typical ldcv proteins, transfected chromogranins a, b, and brain-derived neurotrophic factor (bdnf) colocalize with vmat2. |
2006-01-18 |
2023-08-12 |
Not clear |
| Rebeca Martínez-Turrillas, Joaquín Del Río, Diana Frechill. Sequential changes in BDNF mRNA expression and synaptic levels of AMPA receptor subunits in rat hippocampus after chronic antidepressant treatment. Neuropharmacology. vol 49. issue 8. 2006-01-17. PMID:16143352. |
sequential changes in bdnf mrna expression and synaptic levels of ampa receptor subunits in rat hippocampus after chronic antidepressant treatment. |
2006-01-17 |
2023-08-12 |
rat |
| Rebeca Martínez-Turrillas, Joaquín Del Río, Diana Frechill. Sequential changes in BDNF mRNA expression and synaptic levels of AMPA receptor subunits in rat hippocampus after chronic antidepressant treatment. Neuropharmacology. vol 49. issue 8. 2006-01-17. PMID:16143352. |
here we looked for the time course of the effect of different doses of two antidepressants, desipramine (dmi) and paroxetine (par), which differentially affect monoamine reuptake, on bdnf mrna expression in hippocampal subfields (ca1, ca3 and dentate gyrus) and levels of ampar subunits in total and membrane-enriched extracts from rat hippocampus. |
2006-01-17 |
2023-08-12 |
rat |
| Rebeca Martínez-Turrillas, Joaquín Del Río, Diana Frechill. Sequential changes in BDNF mRNA expression and synaptic levels of AMPA receptor subunits in rat hippocampus after chronic antidepressant treatment. Neuropharmacology. vol 49. issue 8. 2006-01-17. PMID:16143352. |
par produced a time- and dose-dependent increase of bdnf expression in the three hippocampal subfields examined. |
2006-01-17 |
2023-08-12 |
rat |
| Rebeca Martínez-Turrillas, Joaquín Del Río, Diana Frechill. Sequential changes in BDNF mRNA expression and synaptic levels of AMPA receptor subunits in rat hippocampus after chronic antidepressant treatment. Neuropharmacology. vol 49. issue 8. 2006-01-17. PMID:16143352. |
the results suggest that paroxetine, but not desipramine, enhances synaptic plasticity in the hippocampus by increasing bdnf mrna expression, which determines a later ampar subunit trafficking to synaptic membranes. |
2006-01-17 |
2023-08-12 |
rat |
| Barbara Monti, Chiara Berteotti, Antonio Contestabil. Dysregulation of memory-related proteins in the hippocampus of aged rats and their relation with cognitive impairment. Hippocampus. vol 15. issue 8. 2006-01-12. PMID:16086428. |
two other creb-regulated proteins involved in memory consolidation, the neurotrophin bdnf and the transcription factor c/ebpbeta, are expressed at similar levels in the hippocampus of young-adult and aged rats, but their response to conditioned fear learning appears dysregulated by aging. |
2006-01-12 |
2023-08-12 |
rat |
| Jin Zhou, Huaibo Zhang, Rochelle S Cohen, Subhash C Pande. Effects of estrogen treatment on expression of brain-derived neurotrophic factor and cAMP response element-binding protein expression and phosphorylation in rat amygdaloid and hippocampal structures. Neuroendocrinology. vol 81. issue 5. 2006-01-04. PMID:16179807. |
we investigated the effect of e2 on creb expression and phosphorylation and bdnf expression in the amygdala and hippocampus, areas involved in emotional processing. |
2006-01-04 |
2023-08-12 |
rat |
| Jin Zhou, Huaibo Zhang, Rochelle S Cohen, Subhash C Pande. Effects of estrogen treatment on expression of brain-derived neurotrophic factor and cAMP response element-binding protein expression and phosphorylation in rat amygdaloid and hippocampal structures. Neuroendocrinology. vol 81. issue 5. 2006-01-04. PMID:16179807. |
ovariectomized rats were given 10 microg 17beta-estradiol or vehicle for 14 days and expression of components of the creb signaling pathway, i.e., creb, phosphorylated creb (pcreb), and bdnf in amygdala and hippocampus were investigated using immunogold labeling. |
2006-01-04 |
2023-08-12 |
rat |
| Jin Zhou, Huaibo Zhang, Rochelle S Cohen, Subhash C Pande. Effects of estrogen treatment on expression of brain-derived neurotrophic factor and cAMP response element-binding protein expression and phosphorylation in rat amygdaloid and hippocampal structures. Neuroendocrinology. vol 81. issue 5. 2006-01-04. PMID:16179807. |
e2 increased immunolabeling and mrna levels of bdnf in the medial and basomedial amygdala and ca1 and ca3 regions of the hippocampus, but not in any other amygdaloid or hippocampal regions examined. |
2006-01-04 |
2023-08-12 |
rat |
| Jin Zhou, Huaibo Zhang, Rochelle S Cohen, Subhash C Pande. Effects of estrogen treatment on expression of brain-derived neurotrophic factor and cAMP response element-binding protein expression and phosphorylation in rat amygdaloid and hippocampal structures. Neuroendocrinology. vol 81. issue 5. 2006-01-04. PMID:16179807. |
these data identify a signaling pathway through which e2 increases bdnf expression that may underlie some actions of e2 on affective behavior and indicate neuroanatomical heterogeneity in the e2 effect within the amygdala and hippocampus. |
2006-01-04 |
2023-08-12 |
rat |
| P R Szeszko, R Lipsky, C Mentschel, D Robinson, H Gunduz-Bruce, S Sevy, M Ashtari, B Napolitano, R M Bilder, J M Kane, D Goldman, A K Malhotr. Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation. Molecular psychiatry. vol 10. issue 7. 2005-12-07. PMID:15768049. |
polymorphisms in the bdnf gene may therefore confer risk for schizophrenia through hippocampal pathogenesis and/or making the hippocampus more susceptible to environmental insults. |
2005-12-07 |
2023-08-12 |
human |
| P R Szeszko, R Lipsky, C Mentschel, D Robinson, H Gunduz-Bruce, S Sevy, M Ashtari, B Napolitano, R M Bilder, J M Kane, D Goldman, A K Malhotr. Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation. Molecular psychiatry. vol 10. issue 7. 2005-12-07. PMID:15768049. |
these findings implicate genetic involvement of bdnf in variation of human hippocampal volume and suggest that this effect may be greater among patients compared to healthy volunteers. |
2005-12-07 |
2023-08-12 |
human |
| Daniela D Pollak, Kurt Herkner, Harald Hoeger, Gert Lube. Behavioral testing upregulates pCaMKII, BDNF, PSD-95 and egr-1 in hippocampus of FVB/N mice. Behavioural brain research. vol 163. issue 1. 2005-12-07. PMID:15927279. |
behavioral testing upregulates pcamkii, bdnf, psd-95 and egr-1 in hippocampus of fvb/n mice. |
2005-12-07 |
2023-08-12 |
mouse |
| Cheryl A Frye, Madeline E Rhode. Estrogen-priming can enhance progesterone's anti-seizure effects in part by increasing hippocampal levels of allopregnanolone. Pharmacology, biochemistry, and behavior. vol 81. issue 4. 2005-11-28. PMID:16085296. |
we investigated whether estrogen-priming also has anti-seizure effects by altering progesterone's metabolism to allopregnanolone, or levels of brain-derived neurotrophic factor (bdnf), in the hippocampus. |
2005-11-28 |
2023-08-12 |
rat |
| Cheryl A Frye, Madeline E Rhode. Estrogen-priming can enhance progesterone's anti-seizure effects in part by increasing hippocampal levels of allopregnanolone. Pharmacology, biochemistry, and behavior. vol 81. issue 4. 2005-11-28. PMID:16085296. |
bdnf levels in the hippocampus were increased by estrogen-priming, but reduced by progesterone administration. |
2005-11-28 |
2023-08-12 |
rat |
| Bharathi Hattiangady, Muddanna S Rao, Geetha A Shetty, Ashok K Shett. Brain-derived neurotrophic factor, phosphorylated cyclic AMP response element binding protein and neuropeptide Y decline as early as middle age in the dentate gyrus and CA1 and CA3 subfields of the hippocampus. Experimental neurology. vol 195. issue 2. 2005-11-21. PMID:16002067. |
we provide new evidence that the bdnf concentration, the p-creb immunoreactivity and the number of npy immunopositive interneurons decline considerably by middle age in both dentate gyrus and ca1 and ca3 subfields of the hippocampus. |
2005-11-21 |
2023-08-12 |
rat |