| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sergio Scaccianoce, Paola Del Bianco, Giovanna Paolone, Daniele Caprioli, Antonella M E Modafferi, Paolo Nencini, Aldo Badian. Social isolation selectively reduces hippocampal brain-derived neurotrophic factor without altering plasma corticosterone. Behavioural brain research. vol 168. issue 2. 2006-05-09. PMID:16455145. |
compared to rats housed two per cage, isolated rats showed a significant reduction on bdnf protein concentrations in the hippocampus while no changes were observed in the other brain regions examined. |
2006-05-09 |
2023-08-12 |
rat |
| N Francia, F Cirulli, F Chiarotti, A Antonelli, L Aloe, E Allev. Spatial memory deficits in middle-aged mice correlate with lower exploratory activity and a subordinate status: role of hippocampal neurotrophins. The European journal of neuroscience. vol 23. issue 3. 2006-05-09. PMID:16487153. |
at adulthood, bdnf hippocampal levels, but not specific behaviours, were positively correlated with the ability to learn a spatial task. |
2006-05-09 |
2023-08-12 |
mouse |
| Huina Zhang, Mary M Torregrossa, Emily M Jutkiewicz, Yong-Gong Shi, Kenner C Rice, James H Woods, Stanley J Watson, M C K. Endogenous opioids upregulate brain-derived neurotrophic factor mRNA through delta- and micro-opioid receptors independent of antidepressant-like effects. The European journal of neuroscience. vol 23. issue 4. 2006-05-09. PMID:16519663. |
unlike (+)bw373u86, the enkephalins upregulated bdnf mrna expression in the hippocampus through dor- and mor-mediated mechanisms. |
2006-05-09 |
2023-08-12 |
rat |
| Huina Zhang, Mary M Torregrossa, Emily M Jutkiewicz, Yong-Gong Shi, Kenner C Rice, James H Woods, Stanley J Watson, M C K. Endogenous opioids upregulate brain-derived neurotrophic factor mRNA through delta- and micro-opioid receptors independent of antidepressant-like effects. The European journal of neuroscience. vol 23. issue 4. 2006-05-09. PMID:16519663. |
beta-endorphin, endomorphin-1 and endomorphin-2 significantly increased bdnf mrna levels in the frontal cortex, hippocampus and amygdala without reducing immobility; and most of these effects were reversed by ntx. |
2006-05-09 |
2023-08-12 |
rat |
| Jos Prickaerts, Daniël L A van den Hove, Frederik L P Fierens, Hossein K Kia, Ilse Lenaerts, Thomas Steckle. Chronic corticosterone manipulations in mice affect brain cell proliferation rates, but only partly affect BDNF protein levels. Neuroscience letters. vol 396. issue 1. 2006-04-28. PMID:16326007. |
bdnf protein contents in the hippocampus and subventricular zone were not different between the sham group and adx-placebo group, although bdnf contents were decreased in the chronically cort-treated adx animals. |
2006-04-28 |
2023-08-12 |
mouse |
| Robert H Ring, Janet Alder, Myles Fennell, Evguenia Kouranova, Ira B Black, Smita Thakker-Vari. Transcriptional profiling of brain-derived-neurotrophic factor-induced neuronal plasticity: a novel role for nociceptin in hippocampal neurite outgrowth. Journal of neurobiology. vol 66. issue 4. 2006-04-28. PMID:16408296. |
to elucidate comprehensive transcriptional programs associated with short- and long-term bdnf exposure, we now examine mrna abundance and complexity using affymetrix genechips in cultured hippocampal neurons. |
2006-04-28 |
2023-08-12 |
Not clear |
| Robert H Ring, Janet Alder, Myles Fennell, Evguenia Kouranova, Ira B Black, Smita Thakker-Vari. Transcriptional profiling of brain-derived-neurotrophic factor-induced neuronal plasticity: a novel role for nociceptin in hippocampal neurite outgrowth. Journal of neurobiology. vol 66. issue 4. 2006-04-28. PMID:16408296. |
to determine whether these neuropeptides induced by bdnf mediate neuronal development, we examined their effects on hippocampal neurons. |
2006-04-28 |
2023-08-12 |
Not clear |
| A C Hansson, W H Sommer, M Metsis, I Strömberg, L F Agnati, K Fux. Corticosterone actions on the hippocampal brain-derived neurotrophic factor expression are mediated by exon IV promoter. Journal of neuroendocrinology. vol 18. issue 2. 2006-04-26. PMID:16420279. |
in adrenalectomised rats, corticosterone (10 mg/kg s.c.) induces a robust down-regulation of both bdnf mrna and protein levels in the hippocampus peaking at 2-8 h. to study the role of the individual promoters in the corticosterone response, we employed exon-specific riboprobe in situ hybridisation as well as real-time polymerase chain reaction (pcr) in the dentate gyrus. |
2006-04-26 |
2023-08-12 |
rat |
| A C Hansson, W H Sommer, M Metsis, I Strömberg, L F Agnati, K Fux. Corticosterone actions on the hippocampal brain-derived neurotrophic factor expression are mediated by exon IV promoter. Journal of neuroendocrinology. vol 18. issue 2. 2006-04-26. PMID:16420279. |
it appears as if the exon iv promoter is the major target for corticosterone-mediated transcriptional regulation of bdnf in the hippocampus. |
2006-04-26 |
2023-08-12 |
rat |
| Kuem-Ju Lee, Sung-Jin Kim, Suk-Won Kim, Song-Hyen Choi, You-Chan Shin, Sang-Ha Park, Bo-Hyun Moon, Eujin Cho, Min-Soo Lee, Sang-Hyun Choi, Boe-Gwun Chun, Kyung-Ho Shi. Chronic mild stress decreases survival, but not proliferation, of new-born cells in adult rat hippocampus. Experimental & molecular medicine. vol 38. issue 1. 2006-04-20. PMID:16520552. |
in addition, we measured brain-derived neurotrophic factor (bdnf) mrna in the granule cell layer (gcl) of the hippocampus, because bdnf is known to play an important role in the survival of new-born cells. |
2006-04-20 |
2023-08-12 |
rat |
| Shun-Wei Zhu, Benjamin K Yee, Myriel Nyffeler, Bengt Winblad, Joram Feldon, Abdul H Mohamme. Influence of differential housing on emotional behaviour and neurotrophin levels in mice. Behavioural brain research. vol 169. issue 1. 2006-04-18. PMID:16406106. |
baseline levels of bdnf and ngf protein were differently distributed in dorsal and ventral parts of hippocampus in both male and female mice, with levels in the dorsal hippocampal being consistently higher than those in ventral hippocampus. |
2006-04-18 |
2023-08-12 |
mouse |
| Nadine N Johnson-Farley, Tatyana Travkina, Daniel S Cowe. Cumulative activation of akt and consequent inhibition of glycogen synthase kinase-3 by brain-derived neurotrophic factor and insulin-like growth factor-1 in cultured hippocampal neurons. The Journal of pharmacology and experimental therapeutics. vol 316. issue 3. 2006-04-13. PMID:16284277. |
brain-derived neurotrophic factor (bdnf) and insulin-like growth factor-1 (igf-1) seem to play key roles in mediating neuronal plasticity in the hippocampus. |
2006-04-13 |
2023-08-12 |
Not clear |
| Shun-Wei Zhu, Therese M Pham, Elin Aberg, Stefan Brené, Bengt Winblad, Abdul H Mohammed, Vera Bauman. Neurotrophin levels and behaviour in BALB/c mice: impact of intermittent exposure to individual housing and wheel running. Behavioural brain research. vol 167. issue 1. 2006-04-12. PMID:16343654. |
intermittent individual housing increased behavioural activity and reduced nerve growth factor (ngf) and brain-derived neurotrophic factor (bdnf) levels in frontal cortex; while it increased bdnf level in the amygdala and bdnf protein and mrna in hippocampus. |
2006-04-12 |
2023-08-12 |
mouse |
| Shun-Wei Zhu, Therese M Pham, Elin Aberg, Stefan Brené, Bengt Winblad, Abdul H Mohammed, Vera Bauman. Neurotrophin levels and behaviour in BALB/c mice: impact of intermittent exposure to individual housing and wheel running. Behavioural brain research. vol 167. issue 1. 2006-04-12. PMID:16343654. |
besides normalizing motor activity and regulating bdnf and ngf levels in hippocampus, amygdala and cerebellum, physical exercise did not attenuate reduction of cortical ngf and bdnf induced by intermittent individual housing. |
2006-04-12 |
2023-08-12 |
mouse |
| Miao-Kun Sun, Daniel L Alko. Differential gender-related vulnerability to depression induction and converging antidepressant responses in rats. The Journal of pharmacology and experimental therapeutics. vol 316. issue 2. 2006-04-04. PMID:16227471. |
moreover, direct cerebroventricular administration of brain-derived neurotrophic factor (bdnf), whose mrna levels in the hippocampus and frontal cortex reach its lowest levels when estrogen levels are highest, is sufficient to rescue the antidepressive effects in the presence of the protein synthesis inhibitor. |
2006-04-04 |
2023-08-12 |
human |
| Hang Zheng, Yanyou Liu, Wei Li, Bo Yang, Dengbang Chen, Xiaojia Wang, Zhou Jiang, Hongxing Wang, Zhengrong Wang, G Cornelisson, F Halber. Beneficial effects of exercise and its molecular mechanisms on depression in rats. Behavioural brain research. vol 168. issue 1. 2006-04-04. PMID:16290283. |
furthermore, we tested the hypothesis that the capacity of exercise to reverse the harmful effects of cns was relative to the hypothalamo-pituitary-adrenal (hpa) system and brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2006-04-04 |
2023-08-12 |
rat |
| Hang Zheng, Yanyou Liu, Wei Li, Bo Yang, Dengbang Chen, Xiaojia Wang, Zhou Jiang, Hongxing Wang, Zhengrong Wang, G Cornelisson, F Halber. Beneficial effects of exercise and its molecular mechanisms on depression in rats. Behavioural brain research. vol 168. issue 1. 2006-04-04. PMID:16290283. |
further, cns significantly decreased hippocampal bdnf mrna levels. |
2006-04-04 |
2023-08-12 |
rat |
| Hang Zheng, Yanyou Liu, Wei Li, Bo Yang, Dengbang Chen, Xiaojia Wang, Zhou Jiang, Hongxing Wang, Zhengrong Wang, G Cornelisson, F Halber. Beneficial effects of exercise and its molecular mechanisms on depression in rats. Behavioural brain research. vol 168. issue 1. 2006-04-04. PMID:16290283. |
furthermore, exercise counteracted a decrease in hippocampal bdnf mrna caused by cns. |
2006-04-04 |
2023-08-12 |
rat |
| Hang Zheng, Yanyou Liu, Wei Li, Bo Yang, Dengbang Chen, Xiaojia Wang, Zhou Jiang, Hongxing Wang, Zhengrong Wang, G Cornelisson, F Halber. Beneficial effects of exercise and its molecular mechanisms on depression in rats. Behavioural brain research. vol 168. issue 1. 2006-04-04. PMID:16290283. |
the results demonstrated that: (1) exercise reversed the harmful effects of cns on mood and spatial performance in rats and (2) the behavioral changes induced by exercise and/or cns might be associated with hippocampal bdnf levels, and in addition, the hpa system might play different roles in the two different processes. |
2006-04-04 |
2023-08-12 |
rat |
| Rainer Hellweg, Peter Lohmann, Roman Huber, Alexander Kühl, Matthias W Riep. Spatial navigation in complex and radial mazes in APP23 animals and neurotrophin signaling as a biological marker of early impairment. Learning & memory (Cold Spring Harbor, N.Y.). vol 13. issue 1. 2006-04-04. PMID:16418433. |
contrary to the wild-type, hippocampal bdnf levels decreased on training in app23 animals. |
2006-04-04 |
2023-08-12 |
mouse |