| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Helen Scharfman, Jeffrey Goodman, Adam Macleod, Sudar Phani, Cara Antonelli, Susan Crol. Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats. Experimental neurology. vol 192. issue 2. 2005-05-16. PMID:15755552. |
to do so, we compared the effects of bdnf, phosphate-buffered saline (pbs), or bovine serum albumin (bsa) on neurogenesis after infusion into the hippocampus of the normal adult rat, using osmotic pumps that were implanted unilaterally in the dorsal hilus. |
2005-05-16 |
2023-08-12 |
rat |
| Helen Scharfman, Jeffrey Goodman, Adam Macleod, Sudar Phani, Cara Antonelli, Susan Crol. Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats. Experimental neurology. vol 192. issue 2. 2005-05-16. PMID:15755552. |
thus, infusion of bdnf to a local area can have widespread effects on hippocampal neurogenesis. |
2005-05-16 |
2023-08-12 |
rat |
| Helen Scharfman, Jeffrey Goodman, Adam Macleod, Sudar Phani, Cara Antonelli, Susan Crol. Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats. Experimental neurology. vol 192. issue 2. 2005-05-16. PMID:15755552. |
these results are discussed in light of the evidence that bdnf increases neuronal activity in hippocampus. |
2005-05-16 |
2023-08-12 |
rat |
| M Isokaw. N-methyl-D-aspartic acid-induced and Ca-dependent neuronal swelling and its retardation by brain-derived neurotrophic factor in the epileptic hippocampus. Neuroscience. vol 131. issue 4. 2005-05-12. PMID:15749335. |
the present study suggests a functional link between the activation of nmdar and a release of ca2+ from internal stores during the induction of epileptic swelling, and a neuroprotective role of bdnf on the nmdar-induced swelling in the epileptic hippocampus. |
2005-05-12 |
2023-08-12 |
human |
| Isabel G Newton, M Elizabeth Forbes, Claudine Legault, James E Johnson, Judy K Brunso-Bechtold, David R Riddl. Caloric restriction does not reverse aging-related changes in hippocampal BDNF. Neurobiology of aging. vol 26. issue 5. 2005-05-09. PMID:15708443. |
caloric restriction does not reverse aging-related changes in hippocampal bdnf. |
2005-05-09 |
2023-08-12 |
rat |
| Isabel G Newton, M Elizabeth Forbes, Claudine Legault, James E Johnson, Judy K Brunso-Bechtold, David R Riddl. Caloric restriction does not reverse aging-related changes in hippocampal BDNF. Neurobiology of aging. vol 26. issue 5. 2005-05-09. PMID:15708443. |
we tested the hypotheses that aging is associated with a decline in hippocampal brain-derived neurotrophic factor (bdnf), a growth factor that enhances learning and memory, and that cr increases hippocampal bdnf. |
2005-05-09 |
2023-08-12 |
rat |
| Isabel G Newton, M Elizabeth Forbes, Claudine Legault, James E Johnson, Judy K Brunso-Bechtold, David R Riddl. Caloric restriction does not reverse aging-related changes in hippocampal BDNF. Neurobiology of aging. vol 26. issue 5. 2005-05-09. PMID:15708443. |
we compared bdnf protein levels in hippocampal subregions of young, middle-aged and old rats fed cr or ad libitum (al) diets. |
2005-05-09 |
2023-08-12 |
rat |
| Isabel G Newton, M Elizabeth Forbes, Claudine Legault, James E Johnson, Judy K Brunso-Bechtold, David R Riddl. Caloric restriction does not reverse aging-related changes in hippocampal BDNF. Neurobiology of aging. vol 26. issue 5. 2005-05-09. PMID:15708443. |
these data suggest that mnemonic impairments with age do not reflect a decrease in hippocampal bdnf. |
2005-05-09 |
2023-08-12 |
rat |
| J Strauss, C L Barr, C J George, C M Ryan, N King, S Shaikh, M Kovacs, J L Kenned. BDNF and COMT polymorphisms: relation to memory phenotypes in young adults with childhood-onset mood disorder. Neuromolecular medicine. vol 5. issue 3. 2005-05-03. PMID:15626819. |
recent investigations in several species have suggested a role for brain-derived neurotrophic factor (bdnf) in memory, which may be mediated by the influence of bdnf on neuronal plasticity in the hippocampus. |
2005-05-03 |
2023-08-12 |
Not clear |
| Daniel T Radecki, Laurie M Brown, James Martinez, Timothy J Teyle. BDNF protects against stress-induced impairments in spatial learning and memory and LTP. Hippocampus. vol 15. issue 2. 2005-04-28. PMID:15476265. |
the present study investigated whether infusion of brain-derived neurotrophic factor (bdnf) could ameliorate stress-induced impairments in spatial learning and memory as well as hippocampal long-term potentiation (ltp) of rats. |
2005-04-28 |
2023-08-12 |
human |
| Daniel T Radecki, Laurie M Brown, James Martinez, Timothy J Teyle. BDNF protects against stress-induced impairments in spatial learning and memory and LTP. Hippocampus. vol 15. issue 2. 2005-04-28. PMID:15476265. |
bdnf was infused into the left hippocampus (0.5 mul/h) for 14 days, beginning 7 days before the stress exposure. |
2005-04-28 |
2023-08-12 |
human |
| Ray D Beck, Michael A King, Grace K Ha, Jesse D Cushman, Zhi Huang, John M Petitt. IL-2 deficiency results in altered septal and hippocampal cytoarchitecture: relation to development and neurotrophins. Journal of neuroimmunology. vol 160. issue 1-2. 2005-04-28. PMID:15710467. |
to extend our previous findings, several experiments were conducted comparing il-2 ko mice and wild-type littermates to determine (1) whether the gabaergic projection neurons of il-2 ko mice in this region were also affected; (2) if the reduction in septal cholinergic projection neurons found in adult il-2 ko mice is present at weaning (and prior to the development of peripheral autoimmune disease); and (3) if loss of il-2 may result in changes in the neurotrophins, brain-derived neurotrophic factor (bdnf) and nerve growth factor (ngf), involved in maintenance of hippocampal neurons. |
2005-04-28 |
2023-08-12 |
mouse |
| Paul A Adlard, Victoria M Perreau, Carl W Cotma. The exercise-induced expression of BDNF within the hippocampus varies across life-span. Neurobiology of aging. vol 26. issue 4. 2005-04-25. PMID:15653179. |
the exercise-induced expression of bdnf within the hippocampus varies across life-span. |
2005-04-25 |
2023-08-12 |
Not clear |
| Paul A Adlard, Victoria M Perreau, Carl W Cotma. The exercise-induced expression of BDNF within the hippocampus varies across life-span. Neurobiology of aging. vol 26. issue 4. 2005-04-25. PMID:15653179. |
voluntary exercise increases hippocampal brain-derived neurotrophic factor (bdnf) expression in young animals. |
2005-04-25 |
2023-08-12 |
Not clear |
| Paul A Adlard, Victoria M Perreau, Carl W Cotma. The exercise-induced expression of BDNF within the hippocampus varies across life-span. Neurobiology of aging. vol 26. issue 4. 2005-04-25. PMID:15653179. |
in this investigation we examined the induction of bdnf protein in the hippocampus of young (2 months), late middle-aged (15 months) and old (24 months) animals over 4 weeks of exercise. |
2005-04-25 |
2023-08-12 |
Not clear |
| Paul A Adlard, Victoria M Perreau, Carl W Cotma. The exercise-induced expression of BDNF within the hippocampus varies across life-span. Neurobiology of aging. vol 26. issue 4. 2005-04-25. PMID:15653179. |
in whole hippocampal homogenates, only particular bdnf mrna exons were significantly (p<0.05) changed as a result of exercise, with the largest induction occurring in young animals. |
2005-04-25 |
2023-08-12 |
Not clear |
| Yuanyuan Ji, Petti T Pang, Linyin Feng, Bai L. Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons. Nature neuroscience. vol 8. issue 2. 2005-04-25. PMID:15665879. |
here we report that camp regulates bdnf function in mature hippocampal neurons by modulating the signaling and trafficking of its receptor trkb. |
2005-04-25 |
2023-08-12 |
Not clear |
| Helen E Scharfman, Neil J Maclusk. Similarities between actions of estrogen and BDNF in the hippocampus: coincidence or clue? Trends in neurosciences. vol 28. issue 2. 2005-04-25. PMID:15667930. |
similarities between actions of estrogen and bdnf in the hippocampus: coincidence or clue? |
2005-04-25 |
2023-08-12 |
Not clear |
| Helen E Scharfman, Neil J Maclusk. Similarities between actions of estrogen and BDNF in the hippocampus: coincidence or clue? Trends in neurosciences. vol 28. issue 2. 2005-04-25. PMID:15667930. |
this article examines the similarities in the effects of estradiol and bdnf in the hippocampus, in light of the evidence that estradiol can induce bdnf expression, and recent data suggesting that structural and electrophysiological effects of estradiol in the hippocampus might be mediated by bdnf. |
2005-04-25 |
2023-08-12 |
Not clear |
| Helen E Scharfman, Neil J Maclusk. Similarities between actions of estrogen and BDNF in the hippocampus: coincidence or clue? Trends in neurosciences. vol 28. issue 2. 2005-04-25. PMID:15667930. |
the possible role of bdnf as a signaling molecule downstream of estrogen in the hippocampus has implications for our understanding of several cellular and behavioral hippocampal functions, including dendritic and synaptic plasticity, learning and cognitive behavior. |
2005-04-25 |
2023-08-12 |
Not clear |