| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xin-Fu Zhou, Xing-Yun Song, Jin-Hua Zhong, Shahram Barati, Fiona H-H Zhou, Stephen M Johnso. Distribution and localization of pro-brain-derived neurotrophic factor-like immunoreactivity in the peripheral and central nervous system of the adult rat. Journal of neurochemistry. vol 91. issue 3. 2005-03-24. PMID:15485500. |
the results showed that, like mature bdnf, pro-bdnf is localized to nerve terminals in the superficial layers of dorsal horn, trigeminal nuclei, nuclei tractus solitarius, amygdaloid complex, hippocampus, hypothalamus and some peripheral tissues. |
2005-03-24 |
2023-08-12 |
rat |
| Takuma Mori, Keiko Shimizu, Motoharu Hayash. Differential expression patterns of TrkB ligands in the macaque monkey brain. Neuroreport. vol 15. issue 16. 2005-03-14. PMID:15538184. |
in the adult macaque brain, the highest level of bdnf was found in the hippocampus. |
2005-03-14 |
2023-08-12 |
monkey |
| J E Gresack, K M Fric. Environmental enrichment reduces the mnemonic and neural benefits of estrogen. Neuroscience. vol 128. issue 3. 2005-03-04. PMID:15381276. |
at the completion of behavioral testing, hippocampal levels of the presynaptic protein synaptophysin and of brain-derived neurotrophic factor (bdnf) were measured. |
2005-03-04 |
2023-08-12 |
mouse |
| J E Gresack, K M Fric. Environmental enrichment reduces the mnemonic and neural benefits of estrogen. Neuroscience. vol 128. issue 3. 2005-03-04. PMID:15381276. |
in contrast, e2 reduced hippocampal bdnf levels in sc, but not ec, females. |
2005-03-04 |
2023-08-12 |
mouse |
| G De Foubert, S L Carney, C S Robinson, E J Destexhe, R Tomlinson, C A Hicks, T K Murray, J P Gaillard, C Deville, V Xhenseval, C E Thomas, M J O'Neill, T S C Zetterströ. Fluoxetine-induced change in rat brain expression of brain-derived neurotrophic factor varies depending on length of treatment. Neuroscience. vol 128. issue 3. 2005-03-04. PMID:15381288. |
four days of once daily oral administration of fluoxetine induced decreases in bdnf mrna (hippocampus, medial habenular and paraventricular thalamic nuclei). |
2005-03-04 |
2023-08-12 |
rat |
| G De Foubert, S L Carney, C S Robinson, E J Destexhe, R Tomlinson, C A Hicks, T K Murray, J P Gaillard, C Deville, V Xhenseval, C E Thomas, M J O'Neill, T S C Zetterströ. Fluoxetine-induced change in rat brain expression of brain-derived neurotrophic factor varies depending on length of treatment. Neuroscience. vol 128. issue 3. 2005-03-04. PMID:15381288. |
bdnf protein levels remained unaltered until 21 days of fluoxetine treatment, when the numbers of bdnf immunoreactive cells were increased, reaching significance in the pyramidal cell layer of ca1 and ca3 regions of ammon's horn (ca1 and ca3) but not in the other sub-regions of the hippocampus. |
2005-03-04 |
2023-08-12 |
rat |
| G De Foubert, S L Carney, C S Robinson, E J Destexhe, R Tomlinson, C A Hicks, T K Murray, J P Gaillard, C Deville, V Xhenseval, C E Thomas, M J O'Neill, T S C Zetterströ. Fluoxetine-induced change in rat brain expression of brain-derived neurotrophic factor varies depending on length of treatment. Neuroscience. vol 128. issue 3. 2005-03-04. PMID:15381288. |
indicative of the highly regional change within the hippocampus, the elisa method failed to demonstrate significant up-regulation at 21 days, measuring levels of bdnf protein in the whole hippocampus. |
2005-03-04 |
2023-08-12 |
rat |
| Shoshanna Vaynman, Zhe Ying, Fernando Gomez-Pinill. Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition. The European journal of neuroscience. vol 20. issue 10. 2005-03-01. PMID:15548201. |
hippocampal bdnf mediates the efficacy of exercise on synaptic plasticity and cognition. |
2005-03-01 |
2023-08-12 |
Not clear |
| Shoshanna Vaynman, Zhe Ying, Fernando Gomez-Pinill. Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition. The European journal of neuroscience. vol 20. issue 10. 2005-03-01. PMID:15548201. |
a specific immunoadhesin chimera (trkb-igg), that mimics the bdnf receptor, trkb, to selectively bind bdnf molecules, was used to block bdnf in the hippocampus during a 1-week voluntary exercise period. |
2005-03-01 |
2023-08-12 |
Not clear |
| Tetsuji Itoh, Miwa Tokumura, Kohji Ab. Effects of rolipram, a phosphodiesterase 4 inhibitor, in combination with imipramine on depressive behavior, CRE-binding activity and BDNF level in learned helplessness rats. European journal of pharmacology. vol 498. issue 1-3. 2005-02-28. PMID:15363987. |
the reduction of cre-binding activities and bdnf levels in the frontal cortex or hippocampus in learned helplessness rats were ameliorated by treatment with imipramine or rolipram alone. |
2005-02-28 |
2023-08-12 |
rat |
| Tetsuji Itoh, Miwa Tokumura, Kohji Ab. Effects of rolipram, a phosphodiesterase 4 inhibitor, in combination with imipramine on depressive behavior, CRE-binding activity and BDNF level in learned helplessness rats. European journal of pharmacology. vol 498. issue 1-3. 2005-02-28. PMID:15363987. |
cre-binding activities and/or bdnf levels of the frontal cortex and hippocampus were significantly increased by treatment with a combination of rolipram and imipramine compared to those in imipramine-treated rats. |
2005-02-28 |
2023-08-12 |
rat |
| Devin K Binder, Helen E Scharfma. Brain-derived neurotrophic factor. Growth factors (Chur, Switzerland). vol 22. issue 3. 2005-02-25. PMID:15518235. |
basic activity-related changes in the central nervous system are thought to depend on bdnf modification of synaptic transmission, especially in the hippocampus and neocortex. |
2005-02-25 |
2023-08-12 |
Not clear |
| Wolfgang Froestl, Michela Gallagher, Helen Jenkins, Annette Madrid, Thorsten Melcher, Sam Teichman, Cesare G Mondadori, Rodney Pearlma. SGS742: the first GABA(B) receptor antagonist in clinical trials. Biochemical pharmacology. vol 68. issue 8. 2005-02-22. PMID:15451390. |
single doses cause a significant enhancement of the mrna and protein levels of ngf and bdnf in the cortex and hippocampus of rats. |
2005-02-22 |
2023-08-12 |
mouse |
| John E Kolb, Joseph Trettel, Eric S Levin. BDNF enhancement of postsynaptic NMDA receptors is blocked by ethanol. Synapse (New York, N.Y.). vol 55. issue 1. 2005-02-17. PMID:15515007. |
in the present studies, murine brain slices containing hippocampus and neocortex were used to study the effects of bdnf on excitatory neurotransmission. |
2005-02-17 |
2023-08-12 |
Not clear |
| Enrico Tongiorgi, Mara Armellin, Piero Giulio Giulianini, Gianni Bregola, Silvia Zucchini, Beatrice Paradiso, Oswald Steward, Antonino Cattaneo, Michele Simonat. Brain-derived neurotrophic factor mRNA and protein are targeted to discrete dendritic laminas by events that trigger epileptogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 30. 2005-02-15. PMID:15282290. |
here, we demonstrate that epileptogenic stimuli induce a dramatic accumulation of bdnf mrna and protein in the dendrites of hippocampal neurons in vivo. |
2005-02-15 |
2023-08-12 |
Not clear |
| Enrico Tongiorgi, Mara Armellin, Piero Giulio Giulianini, Gianni Bregola, Silvia Zucchini, Beatrice Paradiso, Oswald Steward, Antonino Cattaneo, Michele Simonat. Brain-derived neurotrophic factor mRNA and protein are targeted to discrete dendritic laminas by events that trigger epileptogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 30. 2005-02-15. PMID:15282290. |
bdnf mrna and protein accumulate in dendrites in all hippocampal subfields after pilocarpine seizures and in selected subfields after other epileptogenic stimuli (kainate and kindling). |
2005-02-15 |
2023-08-12 |
Not clear |
| Amelia A Russo-Neustadt, Hilda Alejandre, Celithelma Garcia, Autumn S Ivy, Michael J Che. Hippocampal brain-derived neurotrophic factor expression following treatment with reboxetine, citalopram, and physical exercise. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 12. 2005-02-14. PMID:15199375. |
the antidepressants, reboxetine and citalopram, were used in conjunction with voluntary physical exercise (wheel running) in order to assess the contribution of noradrenergic and serotonergic activation to enhancements in hippocampal brain-derived neurotrophic factor (bdnf) expression resulting from antidepressant treatment and exercise. |
2005-02-14 |
2023-08-12 |
rat |
| Amelia A Russo-Neustadt, Hilda Alejandre, Celithelma Garcia, Autumn S Ivy, Michael J Che. Hippocampal brain-derived neurotrophic factor expression following treatment with reboxetine, citalopram, and physical exercise. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 12. 2005-02-14. PMID:15199375. |
hippocampal bdnf transcription levels (full-length bdnf, as well as exons i-iv) were then assessed via in situ hybridization. |
2005-02-14 |
2023-08-12 |
rat |
| Amelia A Russo-Neustadt, Hilda Alejandre, Celithelma Garcia, Autumn S Ivy, Michael J Che. Hippocampal brain-derived neurotrophic factor expression following treatment with reboxetine, citalopram, and physical exercise. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 12. 2005-02-14. PMID:15199375. |
reboxetine treatment led to a rapid (evident at 2 days) enhancement in bdnf transcription in several hippocampal regions. |
2005-02-14 |
2023-08-12 |
rat |
| Amelia A Russo-Neustadt, Hilda Alejandre, Celithelma Garcia, Autumn S Ivy, Michael J Che. Hippocampal brain-derived neurotrophic factor expression following treatment with reboxetine, citalopram, and physical exercise. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 12. 2005-02-14. PMID:15199375. |
treatment with citalopram led to an increase in bdnf mrna in only one hippocampal region (ca2) after short-term (2 days) treatment, and when combined with exercise, increased bdnf mrna in the ca4 and dentate gyrus after 2 weeks. |
2005-02-14 |
2023-08-12 |
rat |