| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ryuta Koyama, Maki K Yamada, Shigeyoshi Fujisawa, Ritsuko Katoh-Semba, Norio Matsuki, Yuji Ikegay. Brain-derived neurotrophic factor induces hyperexcitable reentrant circuits in the dentate gyrus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 33. 2004-11-08. PMID:15317847. |
using ex vivo hippocampal cultures, we show that prolonged hyperactivity induces mf sprouting and the resultant network reorganizations and that brain-derived neurotrophic factor (bdnf) is necessary and sufficient to evoke these pathogenic plasticities. |
2004-11-08 |
2023-08-12 |
Not clear |
| Petti T Pang, Henry K Teng, Eugene Zaitsev, Newton T Woo, Kazuko Sakata, Shushuang Zhen, Kenneth K Teng, Wing-Ho Yung, Barbara L Hempstead, Bai L. Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity. Science (New York, N.Y.). vol 306. issue 5695. 2004-11-06. PMID:15486301. |
here we report that tpa, by activating the extracellular protease plasmin, converts the precursor probdnf to the mature bdnf (mbdnf), and that such conversion is critical for l-ltp expression in mouse hippocampus. |
2004-11-06 |
2023-08-12 |
mouse |
| Irina Kiprianova, Katharina Schindowski, Oliver von Bohlen und Halbach, Sonja Krause, Rosanna Dono, Markus Schwaninger, Klaus Unsicke. Enlarged infarct volume and loss of BDNF mRNA induction following brain ischemia in mice lacking FGF-2. Experimental neurology. vol 189. issue 2. 2004-10-28. PMID:15380477. |
increased infarct volume in fgf2 null mice was associated with a loss of induction in hippocampal bdnf and trkb mrna expression. |
2004-10-28 |
2023-08-12 |
mouse |
| Ruth M Barrientos, David B Sprunger, Serge Campeau, Linda R Watkins, Jerry W Rudy, Steven F Maie. BDNF mRNA expression in rat hippocampus following contextual learning is blocked by intrahippocampal IL-1beta administration. Journal of neuroimmunology. vol 155. issue 1-2. 2004-10-27. PMID:15342202. |
bdnf mrna expression in rat hippocampus following contextual learning is blocked by intrahippocampal il-1beta administration. |
2004-10-27 |
2023-08-12 |
rat |
| Ruth M Barrientos, David B Sprunger, Serge Campeau, Linda R Watkins, Jerry W Rudy, Steven F Maie. BDNF mRNA expression in rat hippocampus following contextual learning is blocked by intrahippocampal IL-1beta administration. Journal of neuroimmunology. vol 155. issue 1-2. 2004-10-27. PMID:15342202. |
contextual fear conditioning produced a time-dependent increase in bdnf mrna that varied by region of hippocampus. |
2004-10-27 |
2023-08-12 |
rat |
| Ruth M Barrientos, David B Sprunger, Serge Campeau, Linda R Watkins, Jerry W Rudy, Steven F Maie. BDNF mRNA expression in rat hippocampus following contextual learning is blocked by intrahippocampal IL-1beta administration. Journal of neuroimmunology. vol 155. issue 1-2. 2004-10-27. PMID:15342202. |
il-1beta blocked or reduced these increases in bdnf mrna in the ca1, ca2, and dentate gyrus regions of the hippocampus, but had no effect in cortical regions. |
2004-10-27 |
2023-08-12 |
rat |
| Ruth M Barrientos, David B Sprunger, Serge Campeau, Linda R Watkins, Jerry W Rudy, Steven F Maie. BDNF mRNA expression in rat hippocampus following contextual learning is blocked by intrahippocampal IL-1beta administration. Journal of neuroimmunology. vol 155. issue 1-2. 2004-10-27. PMID:15342202. |
these data support the idea that il-1beta-produced memory deficits may be mediated via bdnf mrna reductions in hippocampus. |
2004-10-27 |
2023-08-12 |
rat |
| S C Danzer, E Pan, S Nef, L F Parada, J O McNamar. Altered regulation of brain-derived neurotrophic factor protein in hippocampus following slice preparation. Neuroscience. vol 126. issue 4. 2004-10-08. PMID:15207321. |
first, in cultured slices, bdnf content decreased in the dentate molecular layer and increased in the ca3 pyramidal cell layer and the mossy fiber pathway of the hippocampus after 30 min. |
2004-10-08 |
2023-08-12 |
Not clear |
| S C Danzer, E Pan, S Nef, L F Parada, J O McNamar. Altered regulation of brain-derived neurotrophic factor protein in hippocampus following slice preparation. Neuroscience. vol 126. issue 4. 2004-10-08. PMID:15207321. |
these consequences of hippocampal slice preparation may confound analyses of exogenous or endogenous bdnf on hippocampal neuronal structure or function. |
2004-10-08 |
2023-08-12 |
Not clear |
| Nuno Canas, Inês T Pereira, Joaquim Alexandre Ribeiro, Ana M Sebastiã. Brain-derived neurotrophic factor facilitates glutamate and inhibits GABA release from hippocampal synaptosomes through different mechanisms. Brain research. vol 1016. issue 1. 2004-09-30. PMID:15234254. |
brain-derived neurotrophic factor (bdnf) has an acute excitatory effect on rat hippocampal synaptic transmission. |
2004-09-30 |
2023-08-12 |
rat |
| Nuno Canas, Inês T Pereira, Joaquim Alexandre Ribeiro, Ana M Sebastiã. Brain-derived neurotrophic factor facilitates glutamate and inhibits GABA release from hippocampal synaptosomes through different mechanisms. Brain research. vol 1016. issue 1. 2004-09-30. PMID:15234254. |
to compare the action of bdnf upon the release of excitatory and inhibitory neurotransmitters in the hippocampus, we studied the effect of acutely applied bdnf on the k+-evoked glutamate and on the k+-evoked gamma-aminobutyric acid (gaba) release from rat hippocampal nerve terminals (synaptosomes). |
2004-09-30 |
2023-08-12 |
rat |
| Nuno Canas, Inês T Pereira, Joaquim Alexandre Ribeiro, Ana M Sebastiã. Brain-derived neurotrophic factor facilitates glutamate and inhibits GABA release from hippocampal synaptosomes through different mechanisms. Brain research. vol 1016. issue 1. 2004-09-30. PMID:15234254. |
in contrast, bdnf (3-100 ng/ml) inhibited k+-evoked [3h]gaba release from hippocampal synaptosomes. |
2004-09-30 |
2023-08-12 |
rat |
| Nuno Canas, Inês T Pereira, Joaquim Alexandre Ribeiro, Ana M Sebastiã. Brain-derived neurotrophic factor facilitates glutamate and inhibits GABA release from hippocampal synaptosomes through different mechanisms. Brain research. vol 1016. issue 1. 2004-09-30. PMID:15234254. |
it is concluded that bdnf influences in an opposite way, through distinct mechanisms, the release of glutamate and the release of gaba from hippocampal synaptosomes. |
2004-09-30 |
2023-08-12 |
rat |
| Antonio A Garza, Tony G Ha, Celithelma Garcia, Michael J Chen, Amelia A Russo-Neustad. Exercise, antidepressant treatment, and BDNF mRNA expression in the aging brain. Pharmacology, biochemistry, and behavior. vol 77. issue 2. 2004-09-28. PMID:14751447. |
physical activity and antidepressant treatment increase the expression of brain-derived neurotrophic factor (bdnf) in the young rat hippocampus. |
2004-09-28 |
2023-08-12 |
rat |
| Antonio A Garza, Tony G Ha, Celithelma Garcia, Michael J Chen, Amelia A Russo-Neustad. Exercise, antidepressant treatment, and BDNF mRNA expression in the aging brain. Pharmacology, biochemistry, and behavior. vol 77. issue 2. 2004-09-28. PMID:14751447. |
in situ hybridization revealed that, in young animals, exercise, antidepressant treatment, or their combination elevated bdnf mrna levels in several hippocampal regions, most notably in the ca3, ca4, and dentate gyrus (dg). |
2004-09-28 |
2023-08-12 |
rat |
| Antonio A Garza, Tony G Ha, Celithelma Garcia, Michael J Chen, Amelia A Russo-Neustad. Exercise, antidepressant treatment, and BDNF mRNA expression in the aging brain. Pharmacology, biochemistry, and behavior. vol 77. issue 2. 2004-09-28. PMID:14751447. |
daily swimming also revealed that small amounts of activity led to marked elevations in hippocampal bdnf mrna. |
2004-09-28 |
2023-08-12 |
rat |
| Aymeric Hans, Jeffrey J Bajramovic, Sylvie Syan, Emmanuelle Perret, Irene Dunia, Michel Brahic, Daniel Gonzalez-Duni. Persistent, noncytolytic infection of neurons by Borna disease virus interferes with ERK 1/2 signaling and abrogates BDNF-induced synaptogenesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 7. 2004-09-28. PMID:15033926. |
in the present work, we studied the effect of bdv infection on the response of hippocampal neurons, the main target for this virus, to the neurotrophin bdnf. |
2004-09-28 |
2023-08-12 |
Not clear |
| Matthew E Szapacs, Adam L Numis, Anne M Andrew. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1. Neurobiology of disease. vol 16. issue 3. 2004-09-24. PMID:15262269. |
late onset loss of hippocampal 5-ht and ne is accompanied by increases in bdnf protein expression in mice co-expressing mutant app and ps1. |
2004-09-24 |
2023-08-12 |
mouse |
| Matthew E Szapacs, Adam L Numis, Anne M Andrew. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1. Neurobiology of disease. vol 16. issue 3. 2004-09-24. PMID:15262269. |
in doubly, but not singly mutant mice, hippocampal bdnf levels were increased at 12 (+70%) and 18 months (+170%). |
2004-09-24 |
2023-08-12 |
mouse |
| Matthew E Szapacs, Adam L Numis, Anne M Andrew. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1. Neurobiology of disease. vol 16. issue 3. 2004-09-24. PMID:15262269. |
furthermore, in a different model of serotonergic and noradrenergic degeneration, bdnf protein levels were similarly increased in response to depletions in hippocampal serotonin and norepinephrine caused by the chemical neurotoxin 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine (2'-nh2-mptp). |
2004-09-24 |
2023-08-12 |
mouse |