| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Megumi Adachi, Michel Barrot, Anita E Autry, David Theobald, Lisa M Monteggi. Selective loss of brain-derived neurotrophic factor in the dentate gyrus attenuates antidepressant efficacy. Biological psychiatry. vol 63. issue 7. 2008-04-03. PMID:17981266. |
the neurotrophic hypothesis of depression suggests that loss of bdnf from the hippocampus contributes to an increased vulnerability for depression, whereas upregulation of bdnf in the hippocampus is suggested to mediate antidepressant efficacy. |
2008-04-03 |
2023-08-12 |
Not clear |
| Minjoo Yoo, Insil Joung, Ah Mi Han, Hye Hyun Yoon, Yunhee Kim Kwo. Distinct effect of neurotrophins delivered simultaneously by an adenoviral vector on neurite outgrowth of neural precursor cells from different regions of the brain. Journal of microbiology and biotechnology. vol 17. issue 12. 2008-03-25. PMID:18167452. |
separate transduction of adenovirus delivering bdnf (bdnf-ad) or nt3 (nt3-ad) induced the neuronal differentiation in hippocampal and cortical precursor cells. |
2008-03-25 |
2023-08-12 |
Not clear |
| Curtis E Grace, Tori L Schaefer, Nicole R Herring, Matthew R Skelton, Anne E McCrea, Charles V Vorhees, Michael T William. (+)-Methamphetamine increases corticosterone in plasma and BDNF in brain more than forced swim or isolation in neonatal rats. Synapse (New York, N.Y.). vol 62. issue 2. 2008-03-21. PMID:17992688. |
corticosterone in plasma and brain-derived neurotrophic factor (bdnf) and nerve growth factor (ngf) in neostriatum and hippocampus were examined after one or four treatments on p11 or p15 (0.5, 1.75, 6.5, or 24 h after first dose). |
2008-03-21 |
2023-08-12 |
rat |
| Tsong-Hai Lee, Jen-Tsung Yang, Yu-Shien Ko, Hiroyuki Kato, Yasuto Itoyama, Kyuya Kogur. Influence of ischemic preconditioning on levels of nerve growth factor, brain-derived neurotrophic factor and their high-affinity receptors in hippocampus following forebrain ischemia. Brain research. vol 1187. 2008-03-17. PMID:18036511. |
present report using a confocal laser scanning microscope demonstrated that the hippocampal cells of sham operation gerbils contained immunofluorescent ngf and bdnf and their high-affinity receptors (trka and trkb). |
2008-03-17 |
2023-08-12 |
Not clear |
| Pedro Bekinschtein, Martín Cammarota, Cynthia Katche, Leandro Slipczuk, Janine I Rossato, Andrea Goldin, Ivan Izquierdo, Jorge H Medin. BDNF is essential to promote persistence of long-term memory storage. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 7. 2008-03-13. PMID:18263738. |
here, we show that intrahippocampal delivery of bdnf reverses the deficit in memory persistence caused by inhibition of hippocampal protein synthesis. |
2008-03-13 |
2023-08-12 |
Not clear |
| Pedro Bekinschtein, Martín Cammarota, Cynthia Katche, Leandro Slipczuk, Janine I Rossato, Andrea Goldin, Ivan Izquierdo, Jorge H Medin. BDNF is essential to promote persistence of long-term memory storage. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 7. 2008-03-13. PMID:18263738. |
thus, bdnf is not only necessary, but sufficient to induce a late postacquisition phase in the hippocampus essential for persistence of ltm storage. |
2008-03-13 |
2023-08-12 |
Not clear |
| Gaëlle Naert, Tangui Maurice, Lucia Tapia-Arancibia, Laurent Givaloi. Neuroactive steroids modulate HPA axis activity and cerebral brain-derived neurotrophic factor (BDNF) protein levels in adult male rats. Psychoneuroendocrinology. vol 32. issue 8-10. 2008-03-11. PMID:17928160. |
this stimulation of the hpa axis occurred concomitantly with bdnf modifications at the hippocampus, amygdala and hypothalamus levels. |
2008-03-11 |
2023-08-12 |
rat |
| b' Astrid Bj\\xc3\\xb8rnebekk, Aleksander A Math\\xc3\\xa9, Susanne H M Gruber, Stefan Bren\\xc3\\xa. Social isolation increases number of newly proliferated cells in hippocampus in female flinders sensitive line rats. Hippocampus. vol 17. issue 12. 2008-02-29. PMID:17879375.' |
in an animal model of depression, flinders sensitive line rats, and sprague dawley controls we analyzed if 7 weeks of social isolation of adult animals affect the number of newly proliferated cells in the dentate gyrus or mrnas of neuropeptide y (npy), the npy-y1 receptor, nociceptin, bdnf, and the serotonin 5ht1a and 5ht2a receptors, which are molecules involved in hippocampal plasticity. |
2008-02-29 |
2023-08-12 |
rat |
| Vanja Duric, Kenneth E McCarso. Neurokinin-1 (NK-1) receptor and brain-derived neurotrophic factor (BDNF) gene expression is differentially modulated in the rat spinal dorsal horn and hippocampus during inflammatory pain. Molecular pain. vol 3. 2008-02-21. PMID:17974009. |
neurokinin-1 (nk-1) receptor and brain-derived neurotrophic factor (bdnf) gene expression is differentially modulated in the rat spinal dorsal horn and hippocampus during inflammatory pain. |
2008-02-21 |
2023-08-12 |
rat |
| Vanja Duric, Kenneth E McCarso. Neurokinin-1 (NK-1) receptor and brain-derived neurotrophic factor (BDNF) gene expression is differentially modulated in the rat spinal dorsal horn and hippocampus during inflammatory pain. Molecular pain. vol 3. 2008-02-21. PMID:17974009. |
an opposite effect was observed in the hippocampus, where cfa down-regulated nk-1 receptor and bdnf gene expression, phenomena previously observed in immobilization models of stress and depression. |
2008-02-21 |
2023-08-12 |
rat |
| Vanja Duric, Kenneth E McCarso. Neurokinin-1 (NK-1) receptor and brain-derived neurotrophic factor (BDNF) gene expression is differentially modulated in the rat spinal dorsal horn and hippocampus during inflammatory pain. Molecular pain. vol 3. 2008-02-21. PMID:17974009. |
western blot analyses demonstrated that in the spinal cord, cfa also increased levels of phosphorylated camp response element-binding protein (creb), while in the hippocampus the activation of this transcription factor was significantly reduced, further suggesting that tissue specific transcription of either nk-1 or bdnf genes may be partially regulated by common intracellular transduction mechanisms mediated through activation of creb. |
2008-02-21 |
2023-08-12 |
rat |
| Vanja Duric, Kenneth E McCarso. Neurokinin-1 (NK-1) receptor and brain-derived neurotrophic factor (BDNF) gene expression is differentially modulated in the rat spinal dorsal horn and hippocampus during inflammatory pain. Molecular pain. vol 3. 2008-02-21. PMID:17974009. |
these findings suggest that persistent nociception induces differential regional regulation of nk-1 receptor and bdnf gene expression and creb activation in the cns, potentially reflecting varied roles of these neuromodulators in the spinal cord during persistent sensory activation vs. modulation of the higher brain structures such as the hippocampus. |
2008-02-21 |
2023-08-12 |
rat |
| Shirley L Chao, Jason M Moss, G Jean Harr. Lead-induced alterations of apoptosis and neurotrophic factor mRNA in the developing rat cortex, hippocampus, and cerebellum. Journal of biochemical and molecular toxicology. vol 21. issue 5. 2008-02-19. PMID:17912701. |
the region most vulnerable to alterations occurs in the hippocampus with alterations beginning at pnd 12, in which caspase 3, bcl-x, bdnf increase with lead exposure. |
2008-02-19 |
2023-08-12 |
rat |
| Xueying Jiang, Feng Tian, Yang Du, Neal G Copeland, Nancy A Jenkins, Lino Tessarollo, Xuan Wu, Hongna Pan, Xian-Zhang Hu, Ke Xu, Heather Kenney, Sean E Egan, Helen Turley, Adrian L Harris, Ann M Marini, Robert H Lipsk. BHLHB2 controls Bdnf promoter 4 activity and neuronal excitability. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 5. 2008-02-19. PMID:18234890. |
bhlhb2 gene -/- mice showed increased hippocampal exon 4-specific bdnf mrna levels compared with +/+ littermates under basal and activity-dependent conditions. |
2008-02-19 |
2023-08-12 |
mouse |
| M T Tebano, A Martire, R L Potenza, C Grò, R Pepponi, M Armida, M R Domenici, M A Schwarzschild, J F Chen, P Popol. Adenosine A(2A) receptors are required for normal BDNF levels and BDNF-induced potentiation of synaptic transmission in the mouse hippocampus. Journal of neurochemistry. vol 104. issue 1. 2008-02-18. PMID:18005343. |
adenosine a(2a) receptors are required for normal bdnf levels and bdnf-induced potentiation of synaptic transmission in the mouse hippocampus. |
2008-02-18 |
2023-08-12 |
mouse |
| M T Tebano, A Martire, R L Potenza, C Grò, R Pepponi, M Armida, M R Domenici, M A Schwarzschild, J F Chen, P Popol. Adenosine A(2A) receptors are required for normal BDNF levels and BDNF-induced potentiation of synaptic transmission in the mouse hippocampus. Journal of neurochemistry. vol 104. issue 1. 2008-02-18. PMID:18005343. |
both bdnf and its tyrosine kinase receptors (trkb) are highly expressed in the hippocampus, where an interaction with adenosine a(2a) receptors (a(2a)rs) has been recently reported. |
2008-02-18 |
2023-08-12 |
mouse |
| M T Tebano, A Martire, R L Potenza, C Grò, R Pepponi, M Armida, M R Domenici, M A Schwarzschild, J F Chen, P Popol. Adenosine A(2A) receptors are required for normal BDNF levels and BDNF-induced potentiation of synaptic transmission in the mouse hippocampus. Journal of neurochemistry. vol 104. issue 1. 2008-02-18. PMID:18005343. |
in the present paper, we evaluated the role of a(2a)rs in mediating functional effects of bdnf in hippocampus using a(2a)r knock-out (ko) mice. |
2008-02-18 |
2023-08-12 |
mouse |
| M T Tebano, A Martire, R L Potenza, C Grò, R Pepponi, M Armida, M R Domenici, M A Schwarzschild, J F Chen, P Popol. Adenosine A(2A) receptors are required for normal BDNF levels and BDNF-induced potentiation of synaptic transmission in the mouse hippocampus. Journal of neurochemistry. vol 104. issue 1. 2008-02-18. PMID:18005343. |
in hippocampal slices from wt mice, application of bdnf (10 ng/ml) increased the slope of excitatory post-synaptic field potentials (fepsps), an index of synaptic facilitation. |
2008-02-18 |
2023-08-12 |
mouse |
| M T Tebano, A Martire, R L Potenza, C Grò, R Pepponi, M Armida, M R Domenici, M A Schwarzschild, J F Chen, P Popol. Adenosine A(2A) receptors are required for normal BDNF levels and BDNF-induced potentiation of synaptic transmission in the mouse hippocampus. Journal of neurochemistry. vol 104. issue 1. 2008-02-18. PMID:18005343. |
similarly, genetic deletion of the a(2a)rs abolished bdnf-induced increase of the fepsp slope in slices from a(2a)r ko mice the reduced functional ability of bdnf in a(2a)r ko mice was correlated with the reduction in hippocampal bdnf levels. |
2008-02-18 |
2023-08-12 |
mouse |
| M T Tebano, A Martire, R L Potenza, C Grò, R Pepponi, M Armida, M R Domenici, M A Schwarzschild, J F Chen, P Popol. Adenosine A(2A) receptors are required for normal BDNF levels and BDNF-induced potentiation of synaptic transmission in the mouse hippocampus. Journal of neurochemistry. vol 104. issue 1. 2008-02-18. PMID:18005343. |
in agreement, the pharmacological blockade of a(2)rs by systemic zm 241385 significantly reduced bdnf levels in the hippocampus of normal mice. |
2008-02-18 |
2023-08-12 |
mouse |