| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lêda S B Garcia, Clarissa M Comim, Samira S Valvassori, Gislaine Z Réus, Luciana M Barbosa, Ana Cristina Andreazza, Laura Stertz, Gabriel R Fries, Elaine Cristina Gavioli, Flavio Kapczinski, João Queved. Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 1. 2008-05-02. PMID:17884272. |
in conclusion, our findings suggest that the increase of hippocampal bdnf protein levels induced by ketamine might be necessary to produce a rapid onset of antidepressant action. |
2008-05-02 |
2023-08-12 |
rat |
| R Christensen, A B Marcussen, G Wörtwein, G M Knudsen, S Azna. Abeta(1-42) injection causes memory impairment, lowered cortical and serum BDNF levels, and decreased hippocampal 5-HT(2A) levels. Experimental neurology. vol 210. issue 1. 2008-05-02. PMID:18053988. |
abeta(1-42) injection causes memory impairment, lowered cortical and serum bdnf levels, and decreased hippocampal 5-ht(2a) levels. |
2008-05-02 |
2023-08-12 |
rat |
| R Christensen, A B Marcussen, G Wörtwein, G M Knudsen, S Azna. Abeta(1-42) injection causes memory impairment, lowered cortical and serum BDNF levels, and decreased hippocampal 5-HT(2A) levels. Experimental neurology. vol 210. issue 1. 2008-05-02. PMID:18053988. |
in the abeta(1-42) injected animals we saw an abolished increase in serum bdnf levels that was accompanied by significant lower bdnf levels in frontal cortex and by an 8.5% reduction in hippocampal 5-ht(2a) receptor levels. |
2008-05-02 |
2023-08-12 |
rat |
| R Christensen, A B Marcussen, G Wörtwein, G M Knudsen, S Azna. Abeta(1-42) injection causes memory impairment, lowered cortical and serum BDNF levels, and decreased hippocampal 5-HT(2A) levels. Experimental neurology. vol 210. issue 1. 2008-05-02. PMID:18053988. |
these results indicate that the abeta(1-42) associated memory deficit is associated with an impaired bdnf regulation, which is reflected in lower cortical bdnf levels, and changes in hippocampal 5-ht(2a) receptor levels. |
2008-05-02 |
2023-08-12 |
rat |
| Henrik Viberg, William Mundy, Per Eriksso. Neonatal exposure to decabrominated diphenyl ether (PBDE 209) results in changes in BDNF, CaMKII and GAP-43, biochemical substrates of neuronal survival, growth, and synaptogenesis. Neurotoxicology. vol 29. issue 1. 2008-05-02. PMID:18061678. |
bdnf decreased significantly in hippocampus, but not in cortex, in mice 7 days after exposure to pbde 209. |
2008-05-02 |
2023-08-12 |
mouse |
| Lesley J White, Vanessa Castellan. Exercise and brain health--implications for multiple sclerosis: Part 1--neuronal growth factors. Sports medicine (Auckland, N.Z.). vol 38. issue 2. 2008-04-22. PMID:18201113. |
physical activity has also been shown to up-regulate hippocampal bdnf, which may play a role in mood states, learning and memory to lessen the decline in cognitive function associated with ms. |
2008-04-22 |
2023-08-12 |
Not clear |
| Robert H Lipsky, Ann M Marin. Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity. Annals of the New York Academy of Sciences. vol 1122. 2008-04-21. PMID:18077569. |
convergent findings supporting a role for bdnf in alterations to hippocampal structure and behavior are found in a "humanized" bdnf transgenic mouse. |
2008-04-21 |
2023-08-12 |
mouse |
| Bruno P Guiard, Denis J P David, Thierry Deltheil, Franck Chenu, Erwan Le Maître, Thibault Renoir, Isabelle Leroux-Nicollet, Pierre Sokoloff, Laurence Lanfumey, Michel Hamon, Anne M Andrews, René Hen, Alain M Gardie. Brain-derived neurotrophic factor-deficient mice exhibit a hippocampal hyperserotonergic phenotype. The international journal of neuropsychopharmacology. vol 11. issue 1. 2008-04-15. PMID:17559709. |
heterozygous mutants bdnf +/- mice were utilized to investigate the influence of bdnf on the serotonin (5-ht) system and the activity of the serotonin transporter (sert) in the hippocampus. |
2008-04-15 |
2023-08-12 |
mouse |
| Bruno P Guiard, Denis J P David, Thierry Deltheil, Franck Chenu, Erwan Le Maître, Thibault Renoir, Isabelle Leroux-Nicollet, Pierre Sokoloff, Laurence Lanfumey, Michel Hamon, Anne M Andrews, René Hen, Alain M Gardie. Brain-derived neurotrophic factor-deficient mice exhibit a hippocampal hyperserotonergic phenotype. The international journal of neuropsychopharmacology. vol 11. issue 1. 2008-04-15. PMID:17559709. |
the zero net flux method of quantitative microdialysis revealed that bdnf +/- heterozygous mice have increased basal extracellular 5-ht levels in the hippocampus and decreased 5-ht reuptake capacity. |
2008-04-15 |
2023-08-12 |
mouse |
| Bruno P Guiard, Denis J P David, Thierry Deltheil, Franck Chenu, Erwan Le Maître, Thibault Renoir, Isabelle Leroux-Nicollet, Pierre Sokoloff, Laurence Lanfumey, Michel Hamon, Anne M Andrews, René Hen, Alain M Gardie. Brain-derived neurotrophic factor-deficient mice exhibit a hippocampal hyperserotonergic phenotype. The international journal of neuropsychopharmacology. vol 11. issue 1. 2008-04-15. PMID:17559709. |
in keeping with these results, the selective serotonin reuptake inhibitor paroxetine failed to increase hippocampal extracellular 5-ht levels in bdnf +/- mice while it produced robust effects in wild-type littermates. |
2008-04-15 |
2023-08-12 |
mouse |
| Bruno P Guiard, Denis J P David, Thierry Deltheil, Franck Chenu, Erwan Le Maître, Thibault Renoir, Isabelle Leroux-Nicollet, Pierre Sokoloff, Laurence Lanfumey, Michel Hamon, Anne M Andrews, René Hen, Alain M Gardie. Brain-derived neurotrophic factor-deficient mice exhibit a hippocampal hyperserotonergic phenotype. The international journal of neuropsychopharmacology. vol 11. issue 1. 2008-04-15. PMID:17559709. |
these results provide evidence that constitutive reductions in bdnf modulate sert function reuptake in the hippocampus. |
2008-04-15 |
2023-08-12 |
mouse |
| A M Hein, D L Stutzman, S T Bland, R M Barrientos, L R Watkins, J W Rudy, S F Maie. Prostaglandins are necessary and sufficient to induce contextual fear learning impairments after interleukin-1 beta injections into the dorsal hippocampus. Neuroscience. vol 150. issue 4. 2008-04-08. PMID:18035502. |
in addition to demonstrating the necessity of pgs in il-1beta-mediated memory deficits, we also show that pgs injected directly into the dorsal hippocampus are sufficient to impair context memory and significantly reduce post-conditioning levels of bdnf within the hippocampus, suggesting a possible mechanism for the memory-impairing effects of pgs. |
2008-04-08 |
2023-08-12 |
rat |
| Gregorio Segovia, Alberto Del Arco, Marta de Blas, Pedro Garrido, Francisco Mor. Effects of an enriched environment on the release of dopamine in the prefrontal cortex produced by stress and on working memory during aging in the awake rat. Behavioural brain research. vol 187. issue 2. 2008-04-07. PMID:17977609. |
in one of the groups bdnf protein levels were determined in pfc, hippocampus and amygdala. |
2008-04-07 |
2023-08-12 |
rat |
| Gregorio Segovia, Alberto Del Arco, Marta de Blas, Pedro Garrido, Francisco Mor. Effects of an enriched environment on the release of dopamine in the prefrontal cortex produced by stress and on working memory during aging in the awake rat. Behavioural brain research. vol 187. issue 2. 2008-04-07. PMID:17977609. |
the bdnf protein levels were increased by environmental enrichment in the hippocampus and amygdala, but not in the pfc. |
2008-04-07 |
2023-08-12 |
rat |
| C Chiaruttini, M Sonego, G Baj, M Simonato, E Tongiorg. BDNF mRNA splice variants display activity-dependent targeting to distinct hippocampal laminae. Molecular and cellular neurosciences. vol 37. issue 1. 2008-04-04. PMID:17919921. |
bdnf mrna splice variants display activity-dependent targeting to distinct hippocampal laminae. |
2008-04-04 |
2023-08-12 |
rat |
| C Chiaruttini, M Sonego, G Baj, M Simonato, E Tongiorg. BDNF mRNA splice variants display activity-dependent targeting to distinct hippocampal laminae. Molecular and cellular neurosciences. vol 37. issue 1. 2008-04-04. PMID:17919921. |
we determined the distribution of five bdnf splice variants in the soma and dendrites of rat hippocampal principal neurons, after application of stimuli that prompt bdnf mrna accumulation in dendrites (epileptogenic seizures). |
2008-04-04 |
2023-08-12 |
rat |
| Marianne H Larsen, Anders Hay-Schmidt, Lars C B Rønn, Jens D Mikkelse. Temporal expression of brain-derived neurotrophic factor (BDNF) mRNA in the rat hippocampus after treatment with selective and mixed monoaminergic antidepressants. European journal of pharmacology. vol 578. issue 2-3. 2008-04-03. PMID:17950272. |
temporal expression of brain-derived neurotrophic factor (bdnf) mrna in the rat hippocampus after treatment with selective and mixed monoaminergic antidepressants. |
2008-04-03 |
2023-08-12 |
rat |
| Marianne H Larsen, Anders Hay-Schmidt, Lars C B Rønn, Jens D Mikkelse. Temporal expression of brain-derived neurotrophic factor (BDNF) mRNA in the rat hippocampus after treatment with selective and mixed monoaminergic antidepressants. European journal of pharmacology. vol 578. issue 2-3. 2008-04-03. PMID:17950272. |
this study was undertaken to investigate the time-course of the effect of three antidepressants; fluoxetine, imipramine and venlafaxine, which differentially affect monoamine reuptake, on bdnf mrna expression in the hippocampus. |
2008-04-03 |
2023-08-12 |
rat |
| Marianne H Larsen, Anders Hay-Schmidt, Lars C B Rønn, Jens D Mikkelse. Temporal expression of brain-derived neurotrophic factor (BDNF) mRNA in the rat hippocampus after treatment with selective and mixed monoaminergic antidepressants. European journal of pharmacology. vol 578. issue 2-3. 2008-04-03. PMID:17950272. |
the consequences of increased bdnf in the hippocampus are still indefinite. |
2008-04-03 |
2023-08-12 |
rat |
| Marianne H Larsen, Anders Hay-Schmidt, Lars C B Rønn, Jens D Mikkelse. Temporal expression of brain-derived neurotrophic factor (BDNF) mRNA in the rat hippocampus after treatment with selective and mixed monoaminergic antidepressants. European journal of pharmacology. vol 578. issue 2-3. 2008-04-03. PMID:17950272. |
these results suggest that venlafaxine and imipramine, but not fluoxetine, induce neuroplastic effects in the hippocampus through stimulation of bdnf mrna expression, and that the effect on bdnf is not directly translated into regulation of synaptophysin and gap-43 mrna. |
2008-04-03 |
2023-08-12 |
rat |