| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M T Tebano, A Martire, R L Potenza, C Grò, R Pepponi, M Armida, M R Domenici, M A Schwarzschild, J F Chen, P Popol. Adenosine A(2A) receptors are required for normal BDNF levels and BDNF-induced potentiation of synaptic transmission in the mouse hippocampus. Journal of neurochemistry. vol 104. issue 1. 2008-02-18. PMID:18005343. |
these results indicate that the tonic activation of a(2a)rs is required for bdnf-induced potentiation of synaptic transmission and for sustaining a normal bdnf tone in the hippocampus. |
2008-02-18 |
2023-08-12 |
mouse |
| Regina Hünnerkopf, Alexander Strobel, Lise Gutknecht, Burkhard Brocke, Klaus Peter Lesc. Interaction between BDNF Val66Met and dopamine transporter gene variation influences anxiety-related traits. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 12. 2008-02-14. PMID:17392738. |
the involvement in neural plasticity and the mediation of effects of repeated stress exposure and long-term antidepressant treatment on hippocampal neurogenesis supports a critical role of brain-derived neurotrophic factor (bdnf) in the pathophysiology of affective and other stress-related disorders. |
2008-02-14 |
2023-08-12 |
human |
| Regina Hünnerkopf, Alexander Strobel, Lise Gutknecht, Burkhard Brocke, Klaus Peter Lesc. Interaction between BDNF Val66Met and dopamine transporter gene variation influences anxiety-related traits. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 12. 2008-02-14. PMID:17392738. |
a previously reported valine to methionine substitution at amino-acid position 66 (bdnf val66met) seems to account for memory disturbance and hippocampal dysfunction. |
2008-02-14 |
2023-08-12 |
human |
| b' Francesco Angelucci, Susanne H M Gruber, Aram El Khoury, Pietro Attilio Tonali, Aleksander A Math\\xc3\\xa. Chronic amphetamine treatment reduces NGF and BDNF in the rat brain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 17. issue 12. 2008-02-14. PMID:17434716.' |
amphetamine reduced ngf levels in the hippocampus, occipital cortex and hypothalamus and of bdnf in the occipital cortex and hypothalamus. |
2008-02-14 |
2023-08-12 |
human |
| F Gómez-Pinilla, J R Huie, Z Ying, A R Ferguson, E D Crown, K M Baumbauer, V R Edgerton, J W Gra. BDNF and learning: Evidence that instrumental training promotes learning within the spinal cord by up-regulating BDNF expression. Neuroscience. vol 148. issue 4. 2008-02-14. PMID:17719180. |
given the action of brain-derived neurotrophic factor (bdnf) on hippocampal learning, the current studies examined the role of bdnf in spinal learning. |
2008-02-14 |
2023-08-12 |
human |
| Asa Forslin Aronsson, Stefan Spulber, Mircea Oprica, Bengt Winblad, Claes Post, Marianne Schultzber. Alpha-MSH rescues neurons from excitotoxic cell death. Journal of molecular neuroscience : MN. vol 33. issue 3. 2008-02-04. PMID:17952633. |
levels of bdnf were analysed in the hippocampus. |
2008-02-04 |
2023-08-12 |
rat |
| Etsuko Maruyama, Kenji Ogawa, Shogo Endo, Masafumi Tsujimoto, Tsutomu Hashikawa, Takuji Nabetani, Akira Tsugit. Brain-derived neurotrophic factor induces cell surface expression of short-form tenascin R complex in hippocampal postsynapses. The international journal of biochemistry & cell biology. vol 39. issue 10. 2008-01-08. PMID:17618159. |
brain-derived neurotrophic factor (bdnf) is involved in hippocampal functions such as learning and memory and it plays a crucial role in regulating synaptic plasticity. |
2008-01-08 |
2023-08-12 |
mouse |
| Michelle D Amaral, Lucas Pozzo-Mille. BDNF induces calcium elevations associated with IBDNF, a nonselective cationic current mediated by TRPC channels. Journal of neurophysiology. vol 98. issue 4. 2008-01-08. PMID:17699689. |
brain-derived neurotrophic factor (bdnf) has potent actions on hippocampal neurons, but the mechanisms that initiate its effects are poorly understood. |
2008-01-08 |
2023-08-12 |
Not clear |
| Jenru Chen, Takuma Kitanishi, Takamitsu Ikeda, Norio Matsuki, Maki K Yamad. Contextual learning induces an increase in the number of hippocampal CA1 neurons expressing high levels of BDNF. Neurobiology of learning and memory. vol 88. issue 4. 2008-01-08. PMID:17765576. |
we examined behaviorally induced expression of brain-derived neurotrophic factor (bdnf) in area ca1 of the hippocampus. |
2008-01-08 |
2023-08-12 |
rat |
| Nitsan Kozlovsky, Michael A Matar, Zeev Kaplan, Moshe Kotler, Joseph Zohar, Hagit Cohe. Long-term down-regulation of BDNF mRNA in rat hippocampal CA1 subregion correlates with PTSD-like behavioural stress response. The international journal of neuropsychopharmacology. vol 10. issue 6. 2008-01-02. PMID:17291374. |
animals whose behaviour was extremely disrupted by exposure selectively displayed significant down-regulation of mrna for bdnf and up-regulation of trkb mrna in the ca1 subregion of the hippocampus, compared to animals whose behaviour was minimally or partially affected and to unexposed controls. |
2008-01-02 |
2023-08-12 |
rat |
| Nitsan Kozlovsky, Michael A Matar, Zeev Kaplan, Moshe Kotler, Joseph Zohar, Hagit Cohe. Long-term down-regulation of BDNF mRNA in rat hippocampal CA1 subregion correlates with PTSD-like behavioural stress response. The international journal of neuropsychopharmacology. vol 10. issue 6. 2008-01-02. PMID:17291374. |
the consistent long-term the bdnf down-regulation and trkb up-regulation associated with extreme behavioural compromise may be associated with chronic stress-induced psychopathological processes, especially in the hippocampus. |
2008-01-02 |
2023-08-12 |
rat |
| Angela M Betancourt, Nikolay M Filipov, Russell L Car. Alteration of neurotrophins in the hippocampus and cerebral cortex of young rats exposed to chlorpyrifos and methyl parathion. Toxicological sciences : an official journal of the Society of Toxicology. vol 100. issue 2. 2007-12-20. PMID:17893397. |
the effects of postnatal exposure to cps and mps on the expression of messenger rna (mrna) and protein levels for ngf and bdnf were investigated in the frontal cerebral cortex (cortex) and hippocampus of rats. |
2007-12-20 |
2023-08-12 |
rat |
| Angela M Betancourt, Nikolay M Filipov, Russell L Car. Alteration of neurotrophins in the hippocampus and cerebral cortex of young rats exposed to chlorpyrifos and methyl parathion. Toxicological sciences : an official journal of the Society of Toxicology. vol 100. issue 2. 2007-12-20. PMID:17893397. |
total bdnf protein was increased in the hippocampus but decreased in the cortex. |
2007-12-20 |
2023-08-12 |
rat |
| Angela M Betancourt, Nikolay M Filipov, Russell L Car. Alteration of neurotrophins in the hippocampus and cerebral cortex of young rats exposed to chlorpyrifos and methyl parathion. Toxicological sciences : an official journal of the Society of Toxicology. vol 100. issue 2. 2007-12-20. PMID:17893397. |
these results indicate that repeated developmental op exposure during the postnatal period alters ngf and bdnf in the cortex and the hippocampus and the patterns of these alterations differ between regions. |
2007-12-20 |
2023-08-12 |
rat |
| Farah D Lubin, Yajun Ren, Xianghua Xu, Anne E Anderso. Nuclear factor-kappa B regulates seizure threshold and gene transcription following convulsant stimulation. Journal of neurochemistry. vol 103. issue 4. 2007-12-13. PMID:17727632. |
dna-binding studies and chromatin immunoprecipitation assays using hippocampal extracts from animals with status epilepticus revealed that nf-kappab subunits were associated with the candidate kappab-binding elements within promoter 1 of the bdnf gene. |
2007-12-13 |
2023-08-12 |
Not clear |
| Michael J Chen, Amelia A Russo-Neustad. Running exercise- and antidepressant-induced increases in growth and survival-associated signaling molecules are IGF-dependent. Growth factors (Chur, Switzerland). vol 25. issue 2. 2007-12-13. PMID:17852404. |
it is known that physical exercise increases hippocampal brain-derived neurotrophic factor (bdnf) mrna and protein, as well as the expression of several pro-survival signaling proteins and that many of these effects depend on the uptake of peripheral insulin-like growth factor-1 (igf-1) into the cns. |
2007-12-13 |
2023-08-12 |
Not clear |
| Michael J Chen, Amelia A Russo-Neustad. Running exercise- and antidepressant-induced increases in growth and survival-associated signaling molecules are IGF-dependent. Growth factors (Chur, Switzerland). vol 25. issue 2. 2007-12-13. PMID:17852404. |
together, these results indicate that the uptake of peripheral igf-1 in the cns is essential for antidepressant- as well as exercise-induced enhancement in hippocampal bdnf expression and thus, enhanced hippocampal neuronal survival and plasticity. |
2007-12-13 |
2023-08-12 |
Not clear |
| Konrad Lehmann, Enrique Garea Rodriguez, Oliver Kratz, Gunther H Moll, Ralph R Dawirs, Gertraud Teuchert-Nood. Early preweaning methamphetamine and postweaning rearing conditions interfere with the development of peripheral stress parameters and neural growth factors in gerbils. The International journal of neuroscience. vol 117. issue 11. 2007-12-06. PMID:17917931. |
bdnf concentrations were decreased by ir in saline-injected animals in the left prefrontal and parietal cortices and right entorhinal and hippocampal cortices, and in the subcortical regions of both hemispheres. |
2007-12-06 |
2023-08-12 |
Not clear |
| Smita Thakker-Varia, Jennifer Jernstedt Krol, Jacob Nettleton, Parizad M Bilimoria, Debra A Bangasser, Tracey J Shors, Ira B Black, Janet Alde. The neuropeptide VGF produces antidepressant-like behavioral effects and enhances proliferation in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 45. 2007-12-06. PMID:17989282. |
brain-derived neurotrophic factor (bdnf) is upregulated in the hippocampus by antidepressant treatments, and bdnf produces antidepressant-like effects in behavioral models of depression. |
2007-12-06 |
2023-08-12 |
mouse |
| Smita Thakker-Varia, Jennifer Jernstedt Krol, Jacob Nettleton, Parizad M Bilimoria, Debra A Bangasser, Tracey J Shors, Ira B Black, Janet Alde. The neuropeptide VGF produces antidepressant-like behavioral effects and enhances proliferation in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 45. 2007-12-06. PMID:17989282. |
in our previous work, we identified genes induced by bdnf and defined their specific roles in hippocampal neuronal development and plasticity. |
2007-12-06 |
2023-08-12 |
mouse |