| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Taeki Lee, Juri Saruta, Kenichi Sasaguri, Sadao Sato, Keiichi Tsukinok. Allowing animals to bite reverses the effects of immobilization stress on hippocampal neurotrophin expression. Brain research. vol 1195. 2008-05-27. PMID:18191115. |
acute immobilization stress alters the expression of neurotrophins, including brain-derived neurotrophic factor (bdnf) and neurotrophin-3 (nt-3), in rat hippocampus. |
2008-05-27 |
2023-08-12 |
rat |
| Taeki Lee, Juri Saruta, Kenichi Sasaguri, Sadao Sato, Keiichi Tsukinok. Allowing animals to bite reverses the effects of immobilization stress on hippocampal neurotrophin expression. Brain research. vol 1195. 2008-05-27. PMID:18191115. |
decreased bdnf mrna and increased nt-3 mrna expression in hippocampus were detected on real-time polymerase chain reaction (pcr) in the stress group. |
2008-05-27 |
2023-08-12 |
rat |
| Jian Ping Zhou, Ze Guo Feng, Ben Li Yuan, Shou Zhong Yu, Qian Li, Hen Yan Qu, Man Ji Su. Transduced PTD-BDNF fusion protein protects against beta amyloid peptide-induced learning and memory deficits in mice. Brain research. vol 1191. 2008-05-19. PMID:18191117. |
brain-derived neurotrophic factor (bdnf) promotes the survival and differentiation of hippocampal, cortical, and basal forebrain cholinergic neurons. |
2008-05-19 |
2023-08-12 |
mouse |
| Jian Ping Zhou, Ze Guo Feng, Ben Li Yuan, Shou Zhong Yu, Qian Li, Hen Yan Qu, Man Ji Su. Transduced PTD-BDNF fusion protein protects against beta amyloid peptide-induced learning and memory deficits in mice. Brain research. vol 1191. 2008-05-19. PMID:18191117. |
administered recombinant human bdnf (rhbdnf) conjugated with a protein transduction domain (ptd ) is able to survive and promote the growth of hippocampal neurons impaired by abeta25-35 (10 microm) in vitro and transport through the bbb in vivo. |
2008-05-19 |
2023-08-12 |
mouse |
| T Leyhe, Elke Stransky, G W Eschweiler, G Buchkremer, C Lask. Increase of BDNF serum concentration during donepezil treatment of patients with early Alzheimer's disease. European archives of psychiatry and clinical neuroscience. vol 258. issue 2. 2008-05-15. PMID:17990049. |
in an animal model oral administration of an ache-inhibitor lead to an increase of brain derived neurotrophic factor (bdnf) in hippocampus and cortex. |
2008-05-15 |
2023-08-12 |
Not clear |
| S Krause, K Schindowski, S Zechel, O von Bohlen und Halbac. Expression of trkB and trkC receptors and their ligands brain-derived neurotrophic factor and neurotrophin-3 in the murine amygdala. Journal of neuroscience research. vol 86. issue 2. 2008-05-13. PMID:17828769. |
we have therefore examined the expression of trkb, trkc, bdnf, and nt-3 mrna and protein in different amygdalar nuclei as well as in the hippocampal areas ca1-ca3 and the dentate gyrus. |
2008-05-13 |
2023-08-12 |
mouse |
| S Krause, K Schindowski, S Zechel, O von Bohlen und Halbac. Expression of trkB and trkC receptors and their ligands brain-derived neurotrophic factor and neurotrophin-3 in the murine amygdala. Journal of neuroscience research. vol 86. issue 2. 2008-05-13. PMID:17828769. |
the distribution pattern of trkb, trkc, bdnf, and nt-3 mrna in the murine hippocampus is comparable to that seen in rats. |
2008-05-13 |
2023-08-12 |
mouse |
| Toshiaki Yokoi, Daisuke Tokuhara, Mika Saito, Hiroyuki Ichiba, Tsunekazu Yaman. Hippocampal BDNF and TrkB expression in young rats after status epilepticus. Osaka city medical journal. vol 53. issue 2. 2008-05-13. PMID:18432062. |
hippocampal bdnf and trkb expression in young rats after status epilepticus. |
2008-05-13 |
2023-08-12 |
rat |
| Toshiaki Yokoi, Daisuke Tokuhara, Mika Saito, Hiroyuki Ichiba, Tsunekazu Yaman. Hippocampal BDNF and TrkB expression in young rats after status epilepticus. Osaka city medical journal. vol 53. issue 2. 2008-05-13. PMID:18432062. |
we studied age-related susceptibility and vulnerability to kainic acid-induced status epilepticus (kase) in rats in terms of hippocampal expression of brain-derived neurotrophic factor (bdnf) and tyrosine kinase b receptor (trkb). |
2008-05-13 |
2023-08-12 |
rat |
| Megan E Kozisek, David Middlemas, David B Bylun. The differential regulation of BDNF and TrkB levels in juvenile rats after four days of escitalopram and desipramine treatment. Neuropharmacology. vol 54. issue 2. 2008-05-12. PMID:18048068. |
in the present study we report parallel measurements of bdnf mrna and protein in the frontal cortex and hippocampus after four days of twice daily treatments with escitalopram, a selective serotonin reuptake inhibitor, and desipramine, a tricyclic antidepressant. |
2008-05-12 |
2023-08-12 |
rat |
| Natalia Jaworska, Suzanne M Dwyer, Benjamin Rusa. Repeated neonatal separation results in different neurochemical and behavioral changes in adult male and female Mongolian gerbils. Pharmacology, biochemistry, and behavior. vol 88. issue 4. 2008-05-08. PMID:18048094. |
separated males, but not females, showed a significant decrease in hippocampal brain derived neurotrophic factor (bdnf) relative to controls. |
2008-05-08 |
2023-08-12 |
Not clear |
| D Takeuchi, N Sato, M Shimamura, H Kurinami, S Takeda, M Shinohara, S Suzuki, M Kojima, T Ogihara, R Morishit. Alleviation of Abeta-induced cognitive impairment by ultrasound-mediated gene transfer of HGF in a mouse model. Gene therapy. vol 15. issue 8. 2008-05-08. PMID:18288214. |
these beneficial effects of hgf might be due to (1) significant recovery of the vessel density in the dentate gyrus of the hippocampus, (2) upregulation of bdnf, (3) a significant decrease in oxidative stress and (4) synaptic enhancement. |
2008-05-08 |
2023-08-12 |
mouse |
| Ester Aso, Andrés Ozaita, Elsa M Valdizán, Catherine Ledent, Angel Pazos, Rafael Maldonado, Olga Valverd. BDNF impairment in the hippocampus is related to enhanced despair behavior in CB1 knockout mice. Journal of neurochemistry. vol 105. issue 2. 2008-05-06. PMID:18047561. |
bdnf impairment in the hippocampus is related to enhanced despair behavior in cb1 knockout mice. |
2008-05-06 |
2023-08-12 |
mouse |
| Ester Aso, Andrés Ozaita, Elsa M Valdizán, Catherine Ledent, Angel Pazos, Rafael Maldonado, Olga Valverd. BDNF impairment in the hippocampus is related to enhanced despair behavior in CB1 knockout mice. Journal of neurochemistry. vol 105. issue 2. 2008-05-06. PMID:18047561. |
in the present study, cb1 knockout mice exhibited an augmented response to stress revealed by the increased despair behavior and corticosterone levels showed in the tail suspension test and decreased brain derived neurotrophic factor (bdnf) levels in the hippocampus. |
2008-05-06 |
2023-08-12 |
mouse |
| Ester Aso, Andrés Ozaita, Elsa M Valdizán, Catherine Ledent, Angel Pazos, Rafael Maldonado, Olga Valverd. BDNF impairment in the hippocampus is related to enhanced despair behavior in CB1 knockout mice. Journal of neurochemistry. vol 105. issue 2. 2008-05-06. PMID:18047561. |
interestingly, local administration of bdnf in the hippocampus reversed the increased despair behavior of cb1 knockout mice, confirming the crucial role played by bdnf on the emotional impairment of these mutants. |
2008-05-06 |
2023-08-12 |
mouse |
| Ester Aso, Andrés Ozaita, Elsa M Valdizán, Catherine Ledent, Angel Pazos, Rafael Maldonado, Olga Valverd. BDNF impairment in the hippocampus is related to enhanced despair behavior in CB1 knockout mice. Journal of neurochemistry. vol 105. issue 2. 2008-05-06. PMID:18047561. |
these results suggest that the lack of cb1 receptor originates an enhanced response to stress and deficiency in neuronal plasticity by decreasing bdnf levels in the hippocampus that lead to impairment in the responses to emotional disturbances. |
2008-05-06 |
2023-08-12 |
mouse |
| Lêda S B Garcia, Clarissa M Comim, Samira S Valvassori, Gislaine Z Réus, Luciana M Barbosa, Ana Cristina Andreazza, Laura Stertz, Gabriel R Fries, Elaine Cristina Gavioli, Flavio Kapczinski, João Queved. Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 1. 2008-05-02. PMID:17884272. |
acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases bdnf levels in the rat hippocampus. |
2008-05-02 |
2023-08-12 |
rat |
| Lêda S B Garcia, Clarissa M Comim, Samira S Valvassori, Gislaine Z Réus, Luciana M Barbosa, Ana Cristina Andreazza, Laura Stertz, Gabriel R Fries, Elaine Cristina Gavioli, Flavio Kapczinski, João Queved. Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 1. 2008-05-02. PMID:17884272. |
considering that classic antidepressants may take long-lasting time to exhibit their main therapeutic effects, the present study aims to compare the behavioral effects and the bdnf hippocampus levels of acute administration of ketamine and imipramine in rats. |
2008-05-02 |
2023-08-12 |
rat |
| Lêda S B Garcia, Clarissa M Comim, Samira S Valvassori, Gislaine Z Réus, Luciana M Barbosa, Ana Cristina Andreazza, Laura Stertz, Gabriel R Fries, Elaine Cristina Gavioli, Flavio Kapczinski, João Queved. Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 1. 2008-05-02. PMID:17884272. |
afterwards, bdnf protein hippocampal levels were assessed in imipramine- and ketamine-treated rats by elisa-sandwich assay. |
2008-05-02 |
2023-08-12 |
rat |
| Lêda S B Garcia, Clarissa M Comim, Samira S Valvassori, Gislaine Z Réus, Luciana M Barbosa, Ana Cristina Andreazza, Laura Stertz, Gabriel R Fries, Elaine Cristina Gavioli, Flavio Kapczinski, João Queved. Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 1. 2008-05-02. PMID:17884272. |
interesting enough, acute administration of ketamine at the higher dose, but not imipramine, increased bdnf protein levels in the rat hippocampus. |
2008-05-02 |
2023-08-12 |
rat |