| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thierry Deltheil, Bruno P Guiard, Jean-Philippe Guilloux, Lorelei Nicolas, Claudine Deloménie, Christelle Repérant, Erwan Le Maitre, Isabelle Leroux-Nicollet, Saloua Benmansour, François Coudoré, Denis J David, Alain M Gardie. Consequences of changes in BDNF levels on serotonin neurotransmission, 5-HT transporter expression and function: studies in adult mice hippocampus. Pharmacology, biochemistry, and behavior. vol 90. issue 2. 2008-08-12. PMID:17980409. |
indeed, although the elevation of 5-ht outflow induced by chronic administration of selective serotonin reuptake inhibitors (ssris) causes an increase in bdnf protein levels and expression (mrna) in the hippocampus of rodents, the reciprocal interaction has not been demonstrated yet. |
2008-08-12 |
2023-08-12 |
mouse |
| Thierry Deltheil, Bruno P Guiard, Jean-Philippe Guilloux, Lorelei Nicolas, Claudine Deloménie, Christelle Repérant, Erwan Le Maitre, Isabelle Leroux-Nicollet, Saloua Benmansour, François Coudoré, Denis J David, Alain M Gardie. Consequences of changes in BDNF levels on serotonin neurotransmission, 5-HT transporter expression and function: studies in adult mice hippocampus. Pharmacology, biochemistry, and behavior. vol 90. issue 2. 2008-08-12. PMID:17980409. |
thus, the neurochemical sight of this question will be addressed here by examining the consequences of either a constitutive decrease or increase in brain bdnf protein levels on hippocampal extracellular levels of 5-ht in conscious mice. |
2008-08-12 |
2023-08-12 |
mouse |
| Nicola Kuczewski, Christophe Porcher, Nadine Ferrand, Hervé Fiorentino, Christophe Pellegrino, Richard Kolarow, Volkmar Lessmann, Igor Medina, Jean-Luc Gaiars. Backpropagating action potentials trigger dendritic release of BDNF during spontaneous network activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 27. 2008-08-12. PMID:18596175. |
here we transfected cultures of dissociated hippocampal neurons with green fluorescent protein (gfp)-tagged bdnf and combined whole-cell recording, time-lapse fluorescent imaging, and immunostaining to monitor activity-dependent dendritic release of bdnf. |
2008-08-12 |
2023-08-12 |
Not clear |
| Darrick T Balu, Brian A Hoshaw, Jessica E Malberg, Sharon Rosenzweig-Lipson, Lee E Schechter, Irwin Luck. Differential regulation of central BDNF protein levels by antidepressant and non-antidepressant drug treatments. Brain research. vol 1211. 2008-08-08. PMID:18433734. |
repeated applications (10 days) of electroconvulsive shock (ecs), but not a single treatment (1 day), produced 40-100% increases of bdnf protein in the hippocampus, frontal cortex, amygdala, and brainstem. |
2008-08-08 |
2023-08-12 |
rat |
| Darrick T Balu, Brian A Hoshaw, Jessica E Malberg, Sharon Rosenzweig-Lipson, Lee E Schechter, Irwin Luck. Differential regulation of central BDNF protein levels by antidepressant and non-antidepressant drug treatments. Brain research. vol 1211. 2008-08-08. PMID:18433734. |
chronic (21 days), but not acute (1 day), treatment with the tricyclic antidepressant (tca) desipramine (10 mg/kg), the selective serotonin reuptake inhibitor (ssri) fluoxetine (10 mg/kg), and the monoamine oxidase inhibitor (maoi) phenelzine (10 mg/kg) increased bdnf protein levels in the frontal cortex (10-30%), but not in the hippocampus, amygdala, olfactory bulb, and brain stem. |
2008-08-08 |
2023-08-12 |
rat |
| A Berry, A Greco, M Giorgio, P G Pelicci, R de Kloet, E Alleva, L Minghetti, F Cirull. Deletion of the lifespan determinant p66(Shc) improves performance in a spatial memory task, decreases levels of oxidative stress markers in the hippocampus and increases levels of the neurotrophin BDNF in adult mice. Experimental gerontology. vol 43. issue 3. 2008-08-01. PMID:18065182. |
deletion of the lifespan determinant p66(shc) improves performance in a spatial memory task, decreases levels of oxidative stress markers in the hippocampus and increases levels of the neurotrophin bdnf in adult mice. |
2008-08-01 |
2023-08-12 |
mouse |
| A Berry, A Greco, M Giorgio, P G Pelicci, R de Kloet, E Alleva, L Minghetti, F Cirull. Deletion of the lifespan determinant p66(Shc) improves performance in a spatial memory task, decreases levels of oxidative stress markers in the hippocampus and increases levels of the neurotrophin BDNF in adult mice. Experimental gerontology. vol 43. issue 3. 2008-08-01. PMID:18065182. |
p66(shc-/-) adult subjects, compared to wt, overall showed a better performance in the mwm, lower emotionality and a higher pain threshold, in addition to increased basal levels of bdnf in the hippocampus, as well as decreased levels of oxidative stress markers in the same brain area. |
2008-08-01 |
2023-08-12 |
mouse |
| Valeria Conte, Ramesh Raghupathi, Deborah J Watson, Scott Fujimoto, Nicolas C Royo, Niklas Marklund, Nino Stocchetti, Tracy K McIntos. TrkB gene transfer does not alter hippocampal neuronal loss and cognitive deficits following traumatic brain injury in mice. Restorative neurology and neuroscience. vol 26. issue 1. 2008-08-01. PMID:18431005. |
because tbi can result in decreased expression of the trkb receptor, thereby preventing bdnf from exerting potential neuroprotective effects, the contribution of both bdnf and its receptor trkb to hippocampal neuronal loss and cognitive dysfunction were evaluated. |
2008-08-01 |
2023-08-12 |
mouse |
| Jing Jin, Xinhua Bao, Hansen Wang, Hong Pan, Yuzhi Zhang, Xiru W. RNAi-induced down-regulation of Mecp2 expression in the rat brain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 26. issue 5. 2008-07-31. PMID:18396005. |
bdnf mrna expression decreased in the hippocampus, supporting the hypothesis that bdnf may be a target gene of mecp2 in the cns. |
2008-07-31 |
2023-08-12 |
rat |
| Nobuyuki Mochizuki, Norio Takagi, Koji Kurokawa, Chika Onozato, Yoshiyuki Moriyama, Kouichi Tanonaka, Satoshi Take. Injection of neural progenitor cells improved learning and memory dysfunction after cerebral ischemia. Experimental neurology. vol 211. issue 1. 2008-07-30. PMID:18346733. |
these results suggest that the injection of exogenous npcs into the hippocampus can prevent cerebral ischemia-induced learning and memory dysfunction, possibly through maintenance of the bdnf level. |
2008-07-30 |
2023-08-12 |
rat |
| Takahiro Nakajima, Moritoshi Sato, Naoko Akaza, Yoshio Umezaw. Cell-based fluorescent indicator to visualize brain-derived neurotrophic factor secreted from living neurons. ACS chemical biology. vol 3. issue 6. 2008-07-29. PMID:18510313. |
bescell has visualized endogenous bdnf secreted from hippocampal neurons. |
2008-07-29 |
2023-08-12 |
Not clear |
| Tsutomu Takahashi, Michio Suzuki, Masahiko Tsunoda, Yukiko Kawamura, Nagahide Takahashi, Hiroshi Tsuneki, Yasuhiro Kawasaki, Shi-Yu Zhou, Soushi Kobayashi, Toshiyasu Sasaoka, Hikaru Seto, Masayoshi Kurachi, Norio Ozak. Association between the brain-derived neurotrophic factor Val66Met polymorphism and brain morphology in a Japanese sample of schizophrenia and healthy comparisons. Neuroscience letters. vol 435. issue 1. 2008-07-28. PMID:18325670. |
magnetic resonance imaging was used to investigate the relation between the brain-derived neurotrophic factor (bdnf) val66met polymorphism and volumetric measurements for the medial temporal lobe structures (amygdala, hippocampus, and parahippocampal gyrus) and prefrontal sub-regions (the superior frontal gyrus, middle frontal gyrus, inferior frontal gyrus, ventral medial prefrontal cortex, orbitofrontal cortex, and straight gyrus) in a japanese sample of 33 schizophrenia patients and 29 healthy subjects. |
2008-07-28 |
2023-08-12 |
human |
| Juan Ji An, Kusumika Gharami, Guey-Ying Liao, Newton H Woo, Anthony G Lau, Filip Vanevski, Enrique R Torre, Kevin R Jones, Yue Feng, Bai Lu, Baoji X. Distinct role of long 3' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons. Cell. vol 134. issue 1. 2008-07-25. PMID:18614020. |
distinct role of long 3' utr bdnf mrna in spine morphology and synaptic plasticity in hippocampal neurons. |
2008-07-25 |
2023-08-12 |
mouse |
| Juan Ji An, Kusumika Gharami, Guey-Ying Liao, Newton H Woo, Anthony G Lau, Filip Vanevski, Enrique R Torre, Kevin R Jones, Yue Feng, Bai Lu, Baoji X. Distinct role of long 3' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons. Cell. vol 134. issue 1. 2008-07-25. PMID:18614020. |
there is little bdnf in hippocampal dendrites despite normal levels of total bdnf protein. |
2008-07-25 |
2023-08-12 |
mouse |
| Takashi Iwai, Yuki Iinuma, Reiye Kodani, Jun-Ichiro Ok. Neuromedin U inhibits inflammation-mediated memory impairment and neuronal cell-death in rodents. Neuroscience research. vol 61. issue 1. 2008-07-22. PMID:18336945. |
real-time pcr-based experiments indicated that nmu did not affect the mrna level of il-1beta or il-6 increased by lps, whereas it increased that of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2008-07-22 |
2023-08-12 |
mouse |
| B M Fontinha, M J Diógenes, J A Ribeiro, A M Sebastiã. Enhancement of long-term potentiation by brain-derived neurotrophic factor requires adenosine A2A receptor activation by endogenous adenosine. Neuropharmacology. vol 54. issue 6. 2008-07-22. PMID:18384819. |
since high-frequency neuronal firing, such as that inducing long-term potentiation (ltp), favours both a2a receptor activation and bdnf effects on transmission, we now evaluated the influence of adenosine on the facilitatory action of bdnf upon ca1 hippocampal ltp. |
2008-07-22 |
2023-08-12 |
Not clear |
| B M Fontinha, M J Diógenes, J A Ribeiro, A M Sebastiã. Enhancement of long-term potentiation by brain-derived neurotrophic factor requires adenosine A2A receptor activation by endogenous adenosine. Neuropharmacology. vol 54. issue 6. 2008-07-22. PMID:18384819. |
in conclusion, the facilitatory action of bdnf upon hippocampal ltp is critically dependent on the presence of extracellular adenosine and a2a receptor activation through a camp/pka-dependent mechanism. |
2008-07-22 |
2023-08-12 |
Not clear |
| Deirdre R Harvey, Anne-Marie T McGauran, Jonathan Murphy, Lauren Burns, Eoghan McMonagle, Sean Commin. Emergence of an egocentric cue guiding and allocentric inferring strategy that mirrors hippocampal brain-derived neurotrophic factor (BDNF) expression in the Morris water maze. Neurobiology of learning and memory. vol 89. issue 4. 2008-07-15. PMID:17923424. |
emergence of an egocentric cue guiding and allocentric inferring strategy that mirrors hippocampal brain-derived neurotrophic factor (bdnf) expression in the morris water maze. |
2008-07-15 |
2023-08-12 |
Not clear |
| Axel Becker, Gisela Grecksch, Herbert Schwegler, Thomas Roskode. Expression of mRNA of neurotrophic factors and their receptors are significantly altered after subchronic ketamine treatment. Medicinal chemistry (Shariqah (United Arab Emirates)). vol 4. issue 3. 2008-07-15. PMID:18473918. |
with the exception of ngf in the frontal cortex, ket pretreatment did change ngf, nt-3, and bdnf mrna levels in the frontal cortex, the hippocampus, the striatum, the thalamus/hypothalamus region, and in the cerebellum. |
2008-07-15 |
2023-08-12 |
rat |
| Axel Becker, Gisela Grecksch, Herbert Schwegler, Thomas Roskode. Expression of mRNA of neurotrophic factors and their receptors are significantly altered after subchronic ketamine treatment. Medicinal chemistry (Shariqah (United Arab Emirates)). vol 4. issue 3. 2008-07-15. PMID:18473918. |
ris treatment normalised altered nt-3 levels in the hippocampus and balanced bdnf levels in the same structure. |
2008-07-15 |
2023-08-12 |
rat |