| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L S Inozemtseva, E A Karpenko, O V Dolotov, N G Levitskaya, A A Kamensky, L A Andreeva, I A Grivenniko. Intranasal administration of the peptide Selank regulates BDNF expression in the rat hippocampus in vivo. Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections. vol 421. 2008-11-26. PMID:18841804. |
intranasal administration of the peptide selank regulates bdnf expression in the rat hippocampus in vivo. |
2008-11-26 |
2023-08-12 |
rat |
| Beth Levant, Marlies K Ozias, Paul F Davis, Michelle Winter, Kristin L Russell, Susan E Carlson, Gregory A Reed, Kenneth E McCarso. Decreased brain docosahexaenoic acid content produces neurobiological effects associated with depression: Interactions with reproductive status in female rats. Psychoneuroendocrinology. vol 33. issue 9. 2008-11-25. PMID:18707812. |
decreased brain dha was associated with decreased hippocampal bdnf gene expression and increased relative corticosterone response to an intense stressor, regardless of reproductive status. |
2008-11-25 |
2023-08-12 |
rat |
| Philip Barnes, Kerrie L Thoma. Proteolysis of proBDNF is a key regulator in the formation of memory. PloS one. vol 3. issue 9. 2008-11-25. PMID:18813339. |
using infusions of protein synthesis inhibitors, antisense oligonucleotide targeting brain-derived neurotrophic factor (bdnf) mrna or tpa-stop (an inhibitor of the proteolysis of bdnf protein) into the hippocampus of the awake rat, we show that acquisition and extinction of contextual fear memory depended on the increased and decreased proteolysis of probdnf (precursor bdnf) in the hippocampus, respectively. |
2008-11-25 |
2023-08-12 |
rat |
| Abbe H Macbeth, Helen E Scharfman, Neil J Maclusky, Claris Gautreaux, Victoria N Luin. Effects of multiparity on recognition memory, monoaminergic neurotransmitters, and brain-derived neurotrophic factor (BDNF). Hormones and behavior. vol 54. issue 1. 2008-11-18. PMID:17927990. |
brain-derived neurotrophic factor (bdnf) was also measured in hippocampus (ca1, ca3, dentate gyrus) and septum. |
2008-11-18 |
2023-08-12 |
rat |
| Mauricio G Martin, Simona Perga, Laura Trovò, Andrea Rasola, Pontus Holm, Tomi Rantamäki, Tibor Harkany, Eero Castrén, Federica Chiara, Carlos G Dott. Cholesterol loss enhances TrkB signaling in hippocampal neurons aging in vitro. Molecular biology of the cell. vol 19. issue 5. 2008-11-12. PMID:18287532. |
we here show that trkb activity is most robust in the hippocampus of 21-d-old bdnf-knockout mice as well as in old, wild-type, and bdnf heterozygous animals. |
2008-11-12 |
2023-08-12 |
mouse |
| Mauricio G Martin, Simona Perga, Laura Trovò, Andrea Rasola, Pontus Holm, Tomi Rantamäki, Tibor Harkany, Eero Castrén, Federica Chiara, Carlos G Dott. Cholesterol loss enhances TrkB signaling in hippocampal neurons aging in vitro. Molecular biology of the cell. vol 19. issue 5. 2008-11-12. PMID:18287532. |
moreover, robust trkb activity is evident in old but not young hippocampal neurons differentiating in vitro in the absence of any exogenous neurotrophin and also in neurons from bdnf -/- embryos. |
2008-11-12 |
2023-08-12 |
mouse |
| Ozlem Bozdagi, Erin Rich, Sophie Tronel, Masato Sadahiro, Kamara Patterson, Matthew L Shapiro, Cristina M Alberini, George W Huntley, Stephen R J Salto. The neurotrophin-inducible gene Vgf regulates hippocampal function and behavior through a brain-derived neurotrophic factor-dependent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 39. 2008-11-12. PMID:18815270. |
vgf synthesis is stimulated by bdnf, a critical regulator of hippocampal development and function, and two vgf c-terminal peptides increase synaptic activity in cultured hippocampal neurons. |
2008-11-12 |
2023-08-12 |
mouse |
| Ozlem Bozdagi, Erin Rich, Sophie Tronel, Masato Sadahiro, Kamara Patterson, Matthew L Shapiro, Cristina M Alberini, George W Huntley, Stephen R J Salto. The neurotrophin-inducible gene Vgf regulates hippocampal function and behavior through a brain-derived neurotrophic factor-dependent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 39. 2008-11-12. PMID:18815270. |
treatment of rat hippocampal slices with the vgf-derived peptide tlqp62 resulted in transient potentiation through a mechanism that was selectively blocked by the bdnf scavenger trkb-fc, the trk tyrosine kinase inhibitor k252a (100 nm), and tpa stop, an inhibitor of tissue plasminogen activator (tpa), an enzyme involved in pro-bdnf cleavage to bdnf, but was not blocked by the nmda receptor antagonist apv, anti-p75(ntr) function-blocking antiserum, or previous tetanic stimulation. |
2008-11-12 |
2023-08-12 |
mouse |
| Marcelo S Costa, Paulo H Botton, Sabrina Mioranzza, Ana Paula Ardais, Julia D Moreira, Diogo O Souza, Lisiane O Porciúncul. Caffeine improves adult mice performance in the object recognition task and increases BDNF and TrkB independent on phospho-CREB immunocontent in the hippocampus. Neurochemistry international. vol 53. issue 3-4. 2008-11-06. PMID:18620014. |
caffeine improves adult mice performance in the object recognition task and increases bdnf and trkb independent on phospho-creb immunocontent in the hippocampus. |
2008-11-06 |
2023-08-12 |
mouse |
| Marcelo S Costa, Paulo H Botton, Sabrina Mioranzza, Ana Paula Ardais, Julia D Moreira, Diogo O Souza, Lisiane O Porciúncul. Caffeine improves adult mice performance in the object recognition task and increases BDNF and TrkB independent on phospho-CREB immunocontent in the hippocampus. Neurochemistry international. vol 53. issue 3-4. 2008-11-06. PMID:18620014. |
western blotting analysis of hippocampus from caffeine-treated mice revealed an increase in bdnf and trkb immunocontent, compared to their saline-matched controls. |
2008-11-06 |
2023-08-12 |
mouse |
| Marcelo S Costa, Paulo H Botton, Sabrina Mioranzza, Ana Paula Ardais, Julia D Moreira, Diogo O Souza, Lisiane O Porciúncul. Caffeine improves adult mice performance in the object recognition task and increases BDNF and TrkB independent on phospho-CREB immunocontent in the hippocampus. Neurochemistry international. vol 53. issue 3-4. 2008-11-06. PMID:18620014. |
our results suggest that acute treatment with caffeine improves recognition memory, and this effect may be related to an increase of the bdnf and trkb immunocontent in the hippocampus. |
2008-11-06 |
2023-08-12 |
mouse |
| Daniela D Pollak, Francisco J Monje, Lee Zuckerman, Christine A Denny, Michael R Drew, Eric R Kande. An animal model of a behavioral intervention for depression. Neuron. vol 60. issue 1. 2008-11-06. PMID:18940595. |
learned safety also increases the expression of bdnf in the hippocampus and leads to downregulation of genes involved in the dopaminergic and neuropeptidergic but not the serotonergic system in the basolateral amygdala. |
2008-11-06 |
2023-08-12 |
mouse |
| Tsutomu Takahashi, Michio Suzuki, Masahiko Tsunoda, Yukiko Kawamura, Nagahide Takahashi, Nobuhisa Maeno, Yasuhiro Kawasaki, Shi-Yu Zhou, Hirofumi Hagino, Lisha Niu, Hiroshi Tsuneki, Soushi Kobayashi, Toshiyasu Sasaoka, Hikaru Seto, Masayoshi Kurachi, Norio Ozak. The association of genotypic combination of the DRD3 and BDNF polymorphisms on the adhesio interthalamica and medial temporal lobe structures. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 5. 2008-11-05. PMID:18472202. |
this magnetic resonance imaging study investigated the effect of the genotypic combination of the dopamine d3 receptor (drd3) ser9gly and brain-derived neurotrophic factor (bdnf) val66met polymorphisms on the ai length and volumetric measures of the medial temporal lobe structures (amygdala, hippocampus, and parahippocampal gyrus) in 33 schizophrenia patients and 29 healthy controls. |
2008-11-05 |
2023-08-12 |
human |
| Fatma Simsek-Duran, György Lonar. The role of RIM1alpha in BDNF-enhanced glutamate release. Neuropharmacology. vol 55. issue 1. 2008-11-05. PMID:18499195. |
here we demonstrate that bdnf enhances depolarization-evoked efflux of [(3)h]-glutamate from nerve terminals isolated from the ca1 region of the hippocampus. |
2008-11-05 |
2023-08-12 |
mouse |
| Anne-Marie T McGauran, J Bernadette Moore, Declan Madsen, Daniel Barry, Shirley O'Dea, Bernard P Mahon, Sean Commin. A possible role for protein synthesis, extracellular signal-regulated kinase, and brain-derived neurotrophic factor in long-term spatial memory retention in the water maze. Behavioral neuroscience. vol 122. issue 4. 2008-11-05. PMID:18729634. |
a second experiment was designed to investigate the effect of psi on the formation of cue-platform associations in the watermaze, and on bdnf and erk expression in the hippocampus. |
2008-11-05 |
2023-08-12 |
Not clear |
| Gil M Lewitus, Hagit Cohen, Michal Schwart. Reducing post-traumatic anxiety by immunization. Brain, behavior, and immunity. vol 22. issue 7. 2008-11-03. PMID:18562161. |
furthermore, we found that the ability to cope with this stress is interrelated with t-cell trafficking and with the brain and hippocampal bdnf levels. |
2008-11-03 |
2023-08-12 |
mouse |
| Ritsuko Katoh-Semba, Masako Tsuzuki, Noriko Miyazaki, Motoko Matsuda, Chiaki Nakagawa, Satoshi Ichisaka, Kaori Sudo, Satoko Kitajima, Michiko Hamatake, Yoshio Hata, Koh-ichi Nagat. A phase advance of the light-dark cycle stimulates production of BDNF, but not of other neurotrophins, in the adult rat cerebral cortex: association with the activation of CREB. Journal of neurochemistry. vol 106. issue 5. 2008-11-03. PMID:18636983. |
the cerebellum, hippocampus and cerebral cortex containing visual cortex (vcx) showed diurnal variation in bdnf protein levels and the vcx also in nt-3 levels. |
2008-11-03 |
2023-08-12 |
rat |
| Rui Chen, Junji Moriya, Jun-ichi Yamakawa, Takashi Takahashi, Qian Li, Shigeto Morimoto, Kunimitsu Iwai, Hiroyuki Sumino, Nobuo Yamaguchi, Tsugiyasu Kand. Brain atrophy in a murine model of chronic fatigue syndrome and beneficial effect of Hochu-ekki-to (TJ-41). Neurochemical research. vol 33. issue 9. 2008-10-31. PMID:18317925. |
daily running activity, body weight (bw), ratio of cerebral weight to bw (cw/bw) and expression levels of bdnf and bcl-2 mrna in the hippocampus were determined. |
2008-10-31 |
2023-08-12 |
mouse |
| Rui Chen, Junji Moriya, Jun-ichi Yamakawa, Takashi Takahashi, Qian Li, Shigeto Morimoto, Kunimitsu Iwai, Hiroyuki Sumino, Nobuo Yamaguchi, Tsugiyasu Kand. Brain atrophy in a murine model of chronic fatigue syndrome and beneficial effect of Hochu-ekki-to (TJ-41). Neurochemical research. vol 33. issue 9. 2008-10-31. PMID:18317925. |
bdnf and bcl-2 mrna expression levels in the hippocampus were suppressed in the cfs model and tj-41 treated mice, while no significant difference was found between them. |
2008-10-31 |
2023-08-12 |
mouse |
| Rui Chen, Junji Moriya, Jun-ichi Yamakawa, Takashi Takahashi, Qian Li, Shigeto Morimoto, Kunimitsu Iwai, Hiroyuki Sumino, Nobuo Yamaguchi, Tsugiyasu Kand. Brain atrophy in a murine model of chronic fatigue syndrome and beneficial effect of Hochu-ekki-to (TJ-41). Neurochemical research. vol 33. issue 9. 2008-10-31. PMID:18317925. |
in this model, reduced daily activity might have been associated with decreased hippocampal bdnf mrna expression, hippocampal apoptosis and brain atrophy. |
2008-10-31 |
2023-08-12 |
mouse |