| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiu-Ping Zhou, Kong-Yan Wu, Bin Liang, Xiu-Qing Fu, Zhen-Ge Lu. TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 44. 2008-12-22. PMID:18957540. |
furthermore, ggt was activated by neuronal depolarization or bdnf, both of which promote dendritic arborization, in cultured hippocampal neurons. |
2008-12-22 |
2023-08-12 |
mouse |
| M J Robbins, H M Critchlow, A Lloyd, J Cilia, J D Clarke, B Bond, D N C Jones, P R Mayco. Differential expression of IEG mRNA in rat brain following acute treatment with clozapine or haloperidol: a semi-quantitative RT-PCR study. Journal of psychopharmacology (Oxford, England). vol 22. issue 5. 2008-12-16. PMID:18208916. |
in this study, we analysed the expression profile of a series of iegs (c-fos, c-jun, fra-1, krox-20, krox-24, arc, sgk-1, bdnf and narp) in six rat brain regions (prefrontal cortex, hippocampus, striatum, nucleus accumbens, thalamus and cerebellum). |
2008-12-16 |
2023-08-12 |
rat |
| Farid Ahmed, Lino Tessarollo, Carol Thiele, Italo Mocchett. Brain-derived neurotrophic factor modulates expression of chemokine receptors in the brain. Brain research. vol 1227. 2008-12-16. PMID:18588860. |
the content of cxcr4 mrna and proteins was determined in the cerebral cortex and hippocampus of 6-month-old bdnf heterozygous mice and wild type littermates by using polymerase chain reaction and immunohistochemistry, respectively. |
2008-12-16 |
2023-08-12 |
mouse |
| Farid Ahmed, Lino Tessarollo, Carol Thiele, Italo Mocchett. Brain-derived neurotrophic factor modulates expression of chemokine receptors in the brain. Brain research. vol 1227. 2008-12-16. PMID:18588860. |
lastly, bdnf heterozygous mice showed higher levels of ccr5 and cxcr3 mrna than wild type in the cerebral cortex, hippocampus and striatum. |
2008-12-16 |
2023-08-12 |
mouse |
| S Arancibia, M Silhol, F Moulière, J Meffre, I Höllinger, T Maurice, L Tapia-Arancibi. Protective effect of BDNF against beta-amyloid induced neurotoxicity in vitro and in vivo in rats. Neurobiology of disease. vol 31. issue 3. 2008-12-15. PMID:18585459. |
local measurement of bdnf release, number of hippocampal hilar cells expressing srih mrna and assessment of the corpus callosum damage (morphological examination, pyknotic nuclei counting and axon labeling with anti-mbp antibody). |
2008-12-15 |
2023-08-12 |
rat |
| Olaf Schulte-Herbrüggen, Heide Hörtnagl, Gerald Ponath, Matthias Rothermundt, Rainer Hellwe. Distinct regulation of brain-derived neurotrophic factor and noradrenaline in S100B knockout mice. Neuroscience letters. vol 442. issue 2. 2008-12-12. PMID:18638525. |
therefore we investigated levels of serotonin (5-ht) and its metabolite 5-hydroxyindoleacetic acid (5-hiaa), noradrenaline (na), dopamine (da), brain-derived neurotrophic factor (bdnf) and nerve growth factor (ngf) in the hippocampus, frontal cortex and residual neocortex in s100b knock out (s100b ko) mice compared to wildtype controls. |
2008-12-12 |
2023-08-12 |
mouse |
| Olaf Schulte-Herbrüggen, Heide Hörtnagl, Gerald Ponath, Matthias Rothermundt, Rainer Hellwe. Distinct regulation of brain-derived neurotrophic factor and noradrenaline in S100B knockout mice. Neuroscience letters. vol 442. issue 2. 2008-12-12. PMID:18638525. |
there was a significant increase of hippocampal bdnf (+53%) and a decrease of hippocampal (-12%) and residual neocortical (-15%) na in 10-month-old s100b ko mice compared to wildtype mice whereas the other mediators investigated did not show genotype-dependent changes. |
2008-12-12 |
2023-08-12 |
mouse |
| Olaf Schulte-Herbrüggen, Heide Hörtnagl, Gerald Ponath, Matthias Rothermundt, Rainer Hellwe. Distinct regulation of brain-derived neurotrophic factor and noradrenaline in S100B knockout mice. Neuroscience letters. vol 442. issue 2. 2008-12-12. PMID:18638525. |
the increased hippocampal bdnf may represent an endogenous attempt to compensate trophic effects of s100b protein especially on serotonergic neurons, which have been shown to be unaffected in s100b ko mice previously. |
2008-12-12 |
2023-08-12 |
mouse |
| C Gelegen, J van den Heuvel, D A Collier, I C Campbell, H Oppelaar, E Hessel, M J H Ka. Dopaminergic and brain-derived neurotrophic factor signalling in inbred mice exposed to a restricted feeding schedule. Genes, brain, and behavior. vol 7. issue 5. 2008-12-08. PMID:18363853. |
we measured dopamine receptor d2 and bdnf expression levels in the caudate putamen and the hippocampus, respectively, using in situ hybridization. |
2008-12-08 |
2023-08-12 |
mouse |
| C Gelegen, J van den Heuvel, D A Collier, I C Campbell, H Oppelaar, E Hessel, M J H Ka. Dopaminergic and brain-derived neurotrophic factor signalling in inbred mice exposed to a restricted feeding schedule. Genes, brain, and behavior. vol 7. issue 5. 2008-12-08. PMID:18363853. |
these were accompanied by increased dopamine receptor d2 expression in the caudate putamen and reduced bdnf expression in the hippocampus. |
2008-12-08 |
2023-08-12 |
mouse |
| Aderbal S Aguiar, Ana E Speck, Rui D S Prediger, Flávio Kapczinski, Ricardo A Pinh. Downhill training upregulates mice hippocampal and striatal brain-derived neurotrophic factor levels. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 9. 2008-12-01. PMID:18629433. |
this study examined the effects of downhill treadmill exercise on brain-derived neurotrophic factor (bdnf) protein on the hippocampus and striatum of mice. |
2008-12-01 |
2023-08-12 |
mouse |
| Aderbal S Aguiar, Ana E Speck, Rui D S Prediger, Flávio Kapczinski, Ricardo A Pinh. Downhill training upregulates mice hippocampal and striatal brain-derived neurotrophic factor levels. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 9. 2008-12-01. PMID:18629433. |
while level running increased bdnf levels selectively in the hippocampus (68.5%), the eccentric running resulted in a pronounced bdnf increase in both the hippocampus (137.0%) and the striatum (49.9%). |
2008-12-01 |
2023-08-12 |
mouse |
| Ryota Hashimoto, Yoshiya Moriguchi, Fumio Yamashita, Takeyuki Mori, Kiyotaka Nemoto, Takeya Okada, Hiroaki Hori, Hiroko Noguchi, Hiroshi Kunugi, Takashi Ohnish. Dose-dependent effect of the Val66Met polymorphism of the brain-derived neurotrophic factor gene on memory-related hippocampal activity. Neuroscience research. vol 61. issue 4. 2008-11-26. PMID:18501457. |
brain-derived neurotrophic factor (bdnf) plays a critical role in activity-dependent neuroplasticity underlying learning and memory in the hippocampus. |
2008-11-26 |
2023-08-12 |
human |
| Ryota Hashimoto, Yoshiya Moriguchi, Fumio Yamashita, Takeyuki Mori, Kiyotaka Nemoto, Takeya Okada, Hiroaki Hori, Hiroko Noguchi, Hiroshi Kunugi, Takashi Ohnish. Dose-dependent effect of the Val66Met polymorphism of the brain-derived neurotrophic factor gene on memory-related hippocampal activity. Neuroscience research. vol 61. issue 4. 2008-11-26. PMID:18501457. |
recent human studies have indicated that a common single nucleotide polymorphism of the bdnf gene, the val66met polymorphism, has impact on episodic memory, hippocampal morphology and memory-related hippocampal activity measured by functional magnetic resonance imaging (fmri). |
2008-11-26 |
2023-08-12 |
human |
| Ryota Hashimoto, Yoshiya Moriguchi, Fumio Yamashita, Takeyuki Mori, Kiyotaka Nemoto, Takeya Okada, Hiroaki Hori, Hiroko Noguchi, Hiroshi Kunugi, Takashi Ohnish. Dose-dependent effect of the Val66Met polymorphism of the brain-derived neurotrophic factor gene on memory-related hippocampal activity. Neuroscience research. vol 61. issue 4. 2008-11-26. PMID:18501457. |
these data indicated a genetic mechanism for normal variation in human memory and suggest effects of bdnf signaling on hippocampal function in humans. |
2008-11-26 |
2023-08-12 |
human |
| L S Inozemtseva, E A Karpenko, O V Dolotov, N G Levitskaya, A A Kamensky, L A Andreeva, I A Grivenniko. Intranasal administration of the peptide Selank regulates BDNF expression in the rat hippocampus in vivo. Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections. vol 421. 2008-11-26. PMID:18841804. |
intranasal administration of the peptide selank regulates bdnf expression in the rat hippocampus in vivo. |
2008-11-26 |
2023-08-12 |
rat |
| Beth Levant, Marlies K Ozias, Paul F Davis, Michelle Winter, Kristin L Russell, Susan E Carlson, Gregory A Reed, Kenneth E McCarso. Decreased brain docosahexaenoic acid content produces neurobiological effects associated with depression: Interactions with reproductive status in female rats. Psychoneuroendocrinology. vol 33. issue 9. 2008-11-25. PMID:18707812. |
decreased brain dha was associated with decreased hippocampal bdnf gene expression and increased relative corticosterone response to an intense stressor, regardless of reproductive status. |
2008-11-25 |
2023-08-12 |
rat |
| Philip Barnes, Kerrie L Thoma. Proteolysis of proBDNF is a key regulator in the formation of memory. PloS one. vol 3. issue 9. 2008-11-25. PMID:18813339. |
using infusions of protein synthesis inhibitors, antisense oligonucleotide targeting brain-derived neurotrophic factor (bdnf) mrna or tpa-stop (an inhibitor of the proteolysis of bdnf protein) into the hippocampus of the awake rat, we show that acquisition and extinction of contextual fear memory depended on the increased and decreased proteolysis of probdnf (precursor bdnf) in the hippocampus, respectively. |
2008-11-25 |
2023-08-12 |
rat |
| Abbe H Macbeth, Helen E Scharfman, Neil J Maclusky, Claris Gautreaux, Victoria N Luin. Effects of multiparity on recognition memory, monoaminergic neurotransmitters, and brain-derived neurotrophic factor (BDNF). Hormones and behavior. vol 54. issue 1. 2008-11-18. PMID:17927990. |
brain-derived neurotrophic factor (bdnf) was also measured in hippocampus (ca1, ca3, dentate gyrus) and septum. |
2008-11-18 |
2023-08-12 |
rat |
| Mauricio G Martin, Simona Perga, Laura Trovò, Andrea Rasola, Pontus Holm, Tomi Rantamäki, Tibor Harkany, Eero Castrén, Federica Chiara, Carlos G Dott. Cholesterol loss enhances TrkB signaling in hippocampal neurons aging in vitro. Molecular biology of the cell. vol 19. issue 5. 2008-11-12. PMID:18287532. |
we here show that trkb activity is most robust in the hippocampus of 21-d-old bdnf-knockout mice as well as in old, wild-type, and bdnf heterozygous animals. |
2008-11-12 |
2023-08-12 |
mouse |