| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Binith Cheeran, Penelope Talelli, Francesco Mori, Giacomo Koch, Antonio Suppa, Mark Edwards, Henry Houlden, Kailash Bhatia, Richard Greenwood, John C Rothwel. A common polymorphism in the brain-derived neurotrophic factor gene (BDNF) modulates human cortical plasticity and the response to rTMS. The Journal of physiology. vol 586. issue 23. 2009-02-23. PMID:18845611. |
the brain-derived neurotrophic factor gene (bdnf) is one of many genes thought to influence synaptic plasticity in the adult brain and shows a common single nucleotide polymorphism (bdnf val66met) in the normal population that is associated with differences in hippocampal volume and episodic memory. |
2009-02-23 |
2023-08-12 |
human |
| Fernando Gomez-Pinilla, Shoshanna Vaynman, Zhe Yin. Brain-derived neurotrophic factor functions as a metabotrophin to mediate the effects of exercise on cognition. The European journal of neuroscience. vol 28. issue 11. 2009-02-20. PMID:19046371. |
the purpose of the present study was to examine the influence of exercise on rat hippocampal expression of molecules involved in the regulation of energy management and cognitive function, and to determine the role of bdnf in these events. |
2009-02-20 |
2023-08-12 |
rat |
| Ana Rita A Santos, Carlos B Duart. Validation of internal control genes for expression studies: effects of the neurotrophin BDNF on hippocampal neurons. Journal of neuroscience research. vol 86. issue 16. 2009-02-19. PMID:18655199. |
validation of internal control genes for expression studies: effects of the neurotrophin bdnf on hippocampal neurons. |
2009-02-19 |
2023-08-12 |
Not clear |
| Ana Rita A Santos, Carlos B Duart. Validation of internal control genes for expression studies: effects of the neurotrophin BDNF on hippocampal neurons. Journal of neuroscience research. vol 86. issue 16. 2009-02-19. PMID:18655199. |
the neurotrophin brain-derived neurotrophic factor (bdnf) regulates gene expression through activation of multiple signaling cascades, and we have conducted an expression study for the proper validation of internal control genes in bdnf-stimulated cultured hippocampal neurons. |
2009-02-19 |
2023-08-12 |
Not clear |
| Ana Rita A Santos, Carlos B Duart. Validation of internal control genes for expression studies: effects of the neurotrophin BDNF on hippocampal neurons. Journal of neuroscience research. vol 86. issue 16. 2009-02-19. PMID:18655199. |
our data show that tbp (tata box binding protein), ppia (peptidylprolyl isomerase a), pgk1 (phosphoglycerate kinase 1), and hprt1 (hypoxanthine guanine phosphoribosyl transferase i) are the most stable genes under the experimental conditions used, contrasting with tuba1 (tubulin alpha1-a chain) and gapdh (glyceraldehydes-3-phosphate dehydrogenase), two genes widely used as control genes, which showed an unstable expression in hippocampal neurons stimulated with bdnf. |
2009-02-19 |
2023-08-12 |
Not clear |
| Lenir Orlandi Pereira, Patrícia Machado Nabinger, Atahualpa Cauê Paim Strapasson, Patrícia Nardin, Carlos Alberto Saraiva Gonçalves, Ionara Rodrigues Siqueira, Carlos Alexandre Nett. Long-term effects of environmental stimulation following hypoxia-ischemia on the oxidative state and BDNF levels in rat hippocampus and frontal cortex. Brain research. vol 1247. 2009-02-19. PMID:18992724. |
long-term effects of environmental stimulation following hypoxia-ischemia on the oxidative state and bdnf levels in rat hippocampus and frontal cortex. |
2009-02-19 |
2023-08-12 |
rat |
| Lenir Orlandi Pereira, Patrícia Machado Nabinger, Atahualpa Cauê Paim Strapasson, Patrícia Nardin, Carlos Alberto Saraiva Gonçalves, Ionara Rodrigues Siqueira, Carlos Alexandre Nett. Long-term effects of environmental stimulation following hypoxia-ischemia on the oxidative state and BDNF levels in rat hippocampus and frontal cortex. Brain research. vol 1247. 2009-02-19. PMID:18992724. |
moreover, bdnf levels were increased only in the hippocampus of non-stimulated hi group. |
2009-02-19 |
2023-08-12 |
rat |
| Lenir Orlandi Pereira, Patrícia Machado Nabinger, Atahualpa Cauê Paim Strapasson, Patrícia Nardin, Carlos Alberto Saraiva Gonçalves, Ionara Rodrigues Siqueira, Carlos Alexandre Nett. Long-term effects of environmental stimulation following hypoxia-ischemia on the oxidative state and BDNF levels in rat hippocampus and frontal cortex. Brain research. vol 1247. 2009-02-19. PMID:18992724. |
these results suggest that the environmental enrichment protocol bearing cognitive protection is not associated to increases in bdnf expression nor sod activity in hippocampus of the rats, as assessed in adulthood, submitted to neonatal hypoxia-ischemia. |
2009-02-19 |
2023-08-12 |
rat |
| Michal Reichenstein, Moshe Rehavi, Albert Pinhaso. Involvement of pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors in the mechanism of antidepressant action. Journal of molecular neuroscience : MN. vol 36. issue 1-3. 2009-02-17. PMID:18592413. |
in rat hippocampal neurons, prolonged (72-hour) treatment with selective serotonin reuptake inhibitors paroxetine and citalopram significantly up-regulated bdnf and pacap expression and down-regulated pacap receptor (pac1 and vpac2) expression; the tricyclic antidepressant imipramine had an opposite effect. |
2009-02-17 |
2023-08-12 |
rat |
| Sorayya Kheirvari, Kayoko Uezu, Shigeru Yamamoto, Yutaka Nakay. High-dose dietary supplementation of vitamin A induces brain-derived neurotrophic factor and nerve growth factor production in mice with simultaneous deficiency of vitamin A and zinc. Nutritional neuroscience. vol 11. issue 5. 2009-02-13. PMID:18782483. |
levels of bdnf and ngf were measured from extracts of hippocampus, cortex and cerebellum at the end of the third and fifth months. |
2009-02-13 |
2023-08-12 |
mouse |
| Lêda S Garcia, Clarissa M Comim, Samira S Valvassori, Gislaine Z Réus, Ana Cristina Andreazza, Laura Stertz, Gabriel R Fries, Elaine Cristina Gavioli, Flavio Kapczinski, João Queved. Chronic administration of ketamine elicits antidepressant-like effects in rats without affecting hippocampal brain-derived neurotrophic factor protein levels. Basic & clinical pharmacology & toxicology. vol 103. issue 6. 2009-02-12. PMID:19067677. |
brain-derived neurotrophic factor (bdnf) hippocampal levels were assessed in imipramine- and ketamine-treated rats by elisa sandwich assay. |
2009-02-12 |
2023-08-12 |
rat |
| Lêda S Garcia, Clarissa M Comim, Samira S Valvassori, Gislaine Z Réus, Ana Cristina Andreazza, Laura Stertz, Gabriel R Fries, Elaine Cristina Gavioli, Flavio Kapczinski, João Queved. Chronic administration of ketamine elicits antidepressant-like effects in rats without affecting hippocampal brain-derived neurotrophic factor protein levels. Basic & clinical pharmacology & toxicology. vol 103. issue 6. 2009-02-12. PMID:19067677. |
chronic administration of both drugs, ketamine and imipramine, did not modify bdnf protein levels in the rat hippocampus. |
2009-02-12 |
2023-08-12 |
rat |
| Xia Chen, Jie Liu, Xiaosong Gu, Fei Din. Salidroside attenuates glutamate-induced apoptotic cell death in primary cultured hippocampal neurons of rats. Brain research. vol 1238. 2009-02-09. PMID:18680733. |
this study aimed to evaluate the inhibitory effects of salidroside on glutamate-induced cell death in a primary culture of rat hippocampal neurons as compared to brain-derived neurotrophic factor (bdnf), a usual positive control. |
2009-02-09 |
2023-08-12 |
rat |
| J L Spencer, E M Waters, T A Milner, B S McEwe. Estrous cycle regulates activation of hippocampal Akt, LIM kinase, and neurotrophin receptors in C57BL/6 mice. Neuroscience. vol 155. issue 4. 2009-02-06. PMID:18601981. |
therefore, we investigated whether endogenous fluctuations of gonadal steroids modulate hippocampal activation of the akt, limk, and the bdnf receptor trkb in conjunction with spatial memory in female c57bl/6 mice. |
2009-02-06 |
2023-08-12 |
mouse |
| Amy F Richwine, Annie O Parkin, Jessica B Buchanan, Jing Chen, Julie A Markham, Janice M Juraska, Rodney W Johnso. Architectural changes to CA1 pyramidal neurons in adult and aged mice after peripheral immune stimulation. Psychoneuroendocrinology. vol 33. issue 10. 2009-02-06. PMID:18805643. |
after ip lps administration, expression of il-1beta, il-6, and tnfalpha mrna was higher in hippocampus of aged mice compared to young adults whereas ngf and bdnf mrna was reduced similarly in both age groups. |
2009-02-06 |
2023-08-12 |
mouse |
| M E Sublette, Enrique Baca-Garcia, Ramin V Parsey, Maria A Oquendo, Sarina M Rodrigues, Hanga Galfalvy, Yung-Yu Huang, Victoria Arango, J J Man. Effect of BDNF val66met polymorphism on age-related amygdala volume changes in healthy subjects. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 7. 2009-02-03. PMID:18621091. |
healthy volunteers with the valine to methionine polymorphism at codon 66 of the bdnf gene (val66met) exhibit decreased volume of a number of brain structures, including hippocampus, temporal and occipital lobar gray matter volumes, and a negative correlation between age and the volume of bilateral dorsolateral prefrontal cortices. |
2009-02-03 |
2023-08-12 |
human |
| C Agosti, B Borroni, S Archetti, N M Akkawi, A Padovan. The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is not significantly correlated to Transient Global Amnesia: preliminary results of an on-going study in Brescia Province, Italy. Neuroscience letters. vol 443. issue 3. 2009-02-03. PMID:18692116. |
a single nucleotide polymorphism (snp) in the brain-derived neurotrophic factor (bdnf) gene that causes a valine to methionine substitution at codon 66 (val66met) has been demonstrated to affect human memory and hippocampal function in the development and maintenance of adult neurons. |
2009-02-03 |
2023-08-12 |
Not clear |
| B Coupé, I Dutriez-Casteloot, C Breton, F Lefèvre, J Mairesse, A Dickes-Coopman, M Silhol, L Tapia-Arancibia, J Lesage, D Viea. Perinatal undernutrition modifies cell proliferation and brain-derived neurotrophic factor levels during critical time-windows for hypothalamic and hippocampal development in the male rat. Journal of neuroendocrinology. vol 21. issue 1. 2009-02-03. PMID:19094092. |
fr50 rats exhibited a delayed increase of hippocampal bdnf content whereas, in the hypothalamus, bdnf level was augmented from e21 to p14 and associated, at this latter stage, with an increased mrna expression of trkb-t2. |
2009-02-03 |
2023-08-12 |
rat |
| B Coupé, I Dutriez-Casteloot, C Breton, F Lefèvre, J Mairesse, A Dickes-Coopman, M Silhol, L Tapia-Arancibia, J Lesage, D Viea. Perinatal undernutrition modifies cell proliferation and brain-derived neurotrophic factor levels during critical time-windows for hypothalamic and hippocampal development in the male rat. Journal of neuroendocrinology. vol 21. issue 1. 2009-02-03. PMID:19094092. |
taken together, the results obtained in the present study show that mpu changes the time course of production of bdnf and cell proliferation in specific hippocampal and hypothalamic areas during sensitive developmental windows, suggesting that these early perinatal modifications may have long-lasting consequences. |
2009-02-03 |
2023-08-12 |
rat |
| Jason P Chan, Joshua Cordeira, German A Calderon, Lakshmanan K Iyer, Maribel Rio. Depletion of central BDNF in mice impedes terminal differentiation of new granule neurons in the adult hippocampus. Molecular and cellular neurosciences. vol 39. issue 3. 2009-01-29. PMID:18718867. |
depletion of central bdnf in mice impedes terminal differentiation of new granule neurons in the adult hippocampus. |
2009-01-29 |
2023-08-12 |
mouse |