| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jason P Chan, Joshua Cordeira, German A Calderon, Lakshmanan K Iyer, Maribel Rio. Depletion of central BDNF in mice impedes terminal differentiation of new granule neurons in the adult hippocampus. Molecular and cellular neurosciences. vol 39. issue 3. 2009-01-29. PMID:18718867. |
we found that depletion of central bdnf in mice elicited an increase in hippocampal cell proliferation without affecting cell survival or fate specification. |
2009-01-29 |
2023-08-12 |
mouse |
| Jason P Chan, Joshua Cordeira, German A Calderon, Lakshmanan K Iyer, Maribel Rio. Depletion of central BDNF in mice impedes terminal differentiation of new granule neurons in the adult hippocampus. Molecular and cellular neurosciences. vol 39. issue 3. 2009-01-29. PMID:18718867. |
these findings demonstrate that bdnf is required for the terminal differentiation of new neurons in the adult hippocampus. |
2009-01-29 |
2023-08-12 |
mouse |
| b' Astrid Bj\\xc3\\xb8rnebekk, Aleksander A Math\\xc3\\xa9, Susanne H M Gruber, Stefan Bren\\xc3\\xa. Housing conditions modulate escitalopram effects on antidepressive-like behaviour and brain neurochemistry. The international journal of neuropsychopharmacology. vol 11. issue 8. 2009-01-26. PMID:18570703.' |
in female flinders sensitive line (fsl) rats, a model of depression, we compared the effects of three long-term antidepressant treatments: voluntary running, escitalopram and the combination of both on antidepressant-like behaviour in the porsolt swim test (pst), and on regulation of mrna for dopamine and neuropeptides in striatal dopamine pathways and brain-derived neurotrophic factor (bdnf) in hippocampus. |
2009-01-26 |
2023-08-12 |
rat |
| b' Astrid Bj\\xc3\\xb8rnebekk, Aleksander A Math\\xc3\\xa9, Susanne H M Gruber, Stefan Bren\\xc3\\xa. Housing conditions modulate escitalopram effects on antidepressive-like behaviour and brain neurochemistry. The international journal of neuropsychopharmacology. vol 11. issue 8. 2009-01-26. PMID:18570703.' |
running elevated mrna for dynorphin in caudate putamen and bdnf in hippocampus. |
2009-01-26 |
2023-08-12 |
rat |
| Ghanshyam N Pandey, Xinguo Ren, Hooriyah S Rizavi, Robert R Conley, Rosalinda C Roberts, Yogesh Dwived. Brain-derived neurotrophic factor and tyrosine kinase B receptor signalling in post-mortem brain of teenage suicide victims. The international journal of neuropsychopharmacology. vol 11. issue 8. 2009-01-26. PMID:18611289. |
protein and mrna expression of bdnf and of trkb receptors were determined in the prefrontal cortex (pfc), brodmann's area 9 (ba 9), and hippocampus obtained from 29 teenage suicide victims and 25 matched normal control subjects. |
2009-01-26 |
2023-08-12 |
human |
| Ghanshyam N Pandey, Xinguo Ren, Hooriyah S Rizavi, Robert R Conley, Rosalinda C Roberts, Yogesh Dwived. Brain-derived neurotrophic factor and tyrosine kinase B receptor signalling in post-mortem brain of teenage suicide victims. The international journal of neuropsychopharmacology. vol 11. issue 8. 2009-01-26. PMID:18611289. |
the protein expression of bdnf was significantly decreased in the pfc of teenage suicide victims compared with normal control subjects, whereas no change was observed in the hippocampus. |
2009-01-26 |
2023-08-12 |
human |
| Ghanshyam N Pandey, Xinguo Ren, Hooriyah S Rizavi, Robert R Conley, Rosalinda C Roberts, Yogesh Dwived. Brain-derived neurotrophic factor and tyrosine kinase B receptor signalling in post-mortem brain of teenage suicide victims. The international journal of neuropsychopharmacology. vol 11. issue 8. 2009-01-26. PMID:18611289. |
mrna expression of both bdnf and trkb was significantly decreased in the pfc and hippocampus of teenage suicide victims compared with normal control subjects. |
2009-01-26 |
2023-08-12 |
human |
| Ghanshyam N Pandey, Xinguo Ren, Hooriyah S Rizavi, Robert R Conley, Rosalinda C Roberts, Yogesh Dwived. Brain-derived neurotrophic factor and tyrosine kinase B receptor signalling in post-mortem brain of teenage suicide victims. The international journal of neuropsychopharmacology. vol 11. issue 8. 2009-01-26. PMID:18611289. |
these studies indicate a down-regulation of both bdnf and its receptor trkb in the pfc and hippocampus of teenage suicide victims, which suggests that stress and altered bdnf may represent a major vulnerability factor in teenage suicidal behaviour. |
2009-01-26 |
2023-08-12 |
human |
| Yukako Nakajo, Susumu Miyamoto, Yoshikazu Nakano, Jing-Hui Xue, Takuya Hori, Hiroji Yanamot. Genetic increase in brain-derived neurotrophic factor levels enhances learning and memory. Brain research. vol 1241. 2009-01-26. PMID:18801341. |
in a separate set of animals, bdnf protein levels in the cortex, thalamostriatum and the hippocampus were measured quantitatively using elisa. |
2009-01-26 |
2023-08-12 |
mouse |
| Yukako Nakajo, Susumu Miyamoto, Yoshikazu Nakano, Jing-Hui Xue, Takuya Hori, Hiroji Yanamot. Genetic increase in brain-derived neurotrophic factor levels enhances learning and memory. Brain research. vol 1241. 2009-01-26. PMID:18801341. |
in the bdnf (+/-) mice, the bdnf levels in the cortex, the thalamostriatum and the hippocampus were significantly high, compared to the wild-type littermates; 238%, 158%, and 171%, respectively (p<0.01, one-way anova and a post-hoc test in each region). |
2009-01-26 |
2023-08-12 |
mouse |
| Athéna Rebecca Ypsilanti, M Teresa Girão da Cruz, Alison Burgess, Isabelle Auber. The length of hippocampal cholinergic fibers is reduced in the aging brain. Neurobiology of aging. vol 29. issue 11. 2009-01-23. PMID:17507114. |
no significant changes were detected in chat activity or in the amounts of chat protein, nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), tropomyosin related kinase receptor (trk) a, trkb, or p75 neurotrophin receptor (p75(ntr)) in the aged dorsal hippocampus. |
2009-01-23 |
2023-08-12 |
rat |
| Lu-Shiun Her, Lawrence S B Goldstei. Enhanced sensitivity of striatal neurons to axonal transport defects induced by mutant huntingtin. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 50. 2009-01-23. PMID:19074039. |
we found that movement of app and bdnf is impaired in striatal and hippocampal, but not cortical, neurons from presymptomatic homozygous mutant mice carrying 150q huntingtin knock-in mutations. |
2009-01-23 |
2023-08-12 |
mouse |
| Amy C Arai, Nathane Orwi. Factors that regulate KiSS1 gene expression in the hippocampus. Brain research. vol 1243. 2009-01-21. PMID:18834866. |
taken together, kiss1 expression is upregulated by neuronal activity and activation of gpr54 by kisspeptin may in turn contribute to sustain basal bdnf levels required for hippocampal function. |
2009-01-21 |
2023-08-12 |
rat |
| Bianca Topic, Joseph P Huston, Katerina Namestkova, Shun-Wei Zhu, Abdul H Mohammed, Daniela Schul. Extinction-induced "despair" in aged and adult rats: links to neurotrophins in frontal cortex and hippocampus. Neurobiology of learning and memory. vol 90. issue 3. 2009-01-16. PMID:18662794. |
with respect to the neurotrophin hypothesis of depression, nerve-growth factor (ngf), brain-derived neurotrophic factor (bdnf) and neurotrophin-3 (nt-3) protein levels in frontal cortex (fc) and hippocampus (hp) were examined and related to behavioral immobility and rte in the water maze in aged and adult wistar rats. |
2009-01-16 |
2023-08-12 |
human |
| Jiansong Zhou, Lingjiang Li, Shaojun Tang, Xia Cao, Zexuan Li, Weihui Li, Changqi Li, Xianghui Zhan. Effects of serotonin depletion on the hippocampal GR/MR and BDNF expression during the stress adaptation. Behavioural brain research. vol 195. issue 1. 2009-01-12. PMID:18601957. |
effects of serotonin depletion on the hippocampal gr/mr and bdnf expression during the stress adaptation. |
2009-01-12 |
2023-08-12 |
rat |
| Jiansong Zhou, Lingjiang Li, Shaojun Tang, Xia Cao, Zexuan Li, Weihui Li, Changqi Li, Xianghui Zhan. Effects of serotonin depletion on the hippocampal GR/MR and BDNF expression during the stress adaptation. Behavioural brain research. vol 195. issue 1. 2009-01-12. PMID:18601957. |
the para-chloroamphetamine (p-pca) was used to deplete 5-ht in the rat prior to repeated restraint stress (6h/day for 10 days), and determined the consequences of 5-ht depletion on stress-induced alterations of animal behaviors, hippocampal corticosteroid receptor immunoreactivity and the brain-derived neurotrophic factor (bdnf) mrna expression. |
2009-01-12 |
2023-08-12 |
rat |
| Jiansong Zhou, Lingjiang Li, Shaojun Tang, Xia Cao, Zexuan Li, Weihui Li, Changqi Li, Xianghui Zhan. Effects of serotonin depletion on the hippocampal GR/MR and BDNF expression during the stress adaptation. Behavioural brain research. vol 195. issue 1. 2009-01-12. PMID:18601957. |
the study suggest that 5-ht deficiency in the adult hippocampus may impair stress adaptation by suppressing hippocampal gr and bdnf expression. |
2009-01-12 |
2023-08-12 |
rat |
| Phu V Tran, Erik S Carlson, Stephanie J B Fretham, Michael K Georgief. Early-life iron deficiency anemia alters neurotrophic factor expression and hippocampal neuron differentiation in male rats. The Journal of nutrition. vol 138. issue 12. 2009-01-06. PMID:19022978. |
iron deficiency downregulated brain-derived neurotrophic factor (bdnf) expression in the hippocampus without compensatory upregulation of its specific receptor, tyrosine-receptor kinase b. |
2009-01-06 |
2023-08-12 |
rat |
| Phu V Tran, Erik S Carlson, Stephanie J B Fretham, Michael K Georgief. Early-life iron deficiency anemia alters neurotrophic factor expression and hippocampal neuron differentiation in male rats. The Journal of nutrition. vol 138. issue 12. 2009-01-06. PMID:19022978. |
our findings suggest that fetal-neonatal iron deficiency lowers bdnf function and impairs neuronal differentiation in the hippocampus. |
2009-01-06 |
2023-08-12 |
rat |
| Erika Toth, Roman Gersner, Adi Wilf-Yarkoni, Hagit Raizel, Dalit E Dar, Gal Richter-Levin, Ofir Levit, Abraham Zange. Age-dependent effects of chronic stress on brain plasticity and depressive behavior. Journal of neurochemistry. vol 107. issue 2. 2008-12-24. PMID:18752645. |
furthermore, while cms decreased neurogenesis and levels of brain-derived neurotrophic factor (bdnf) in the hippocampus of adult animals, it increased these parameters in young animals. |
2008-12-24 |
2023-08-12 |
Not clear |