| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhaohui Liu, Dongliang Ma, Gaifeng Feng, Yanbing Ma, Haitao H. Recombinant AAV-mediated expression of human BDNF protects neurons against cell apoptosis in Abeta-induced neuronal damage model. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 27. issue 3. 2008-07-02. PMID:17641830. |
cultured rat hippocampal neurons were treated with abeta(25-35) and serued as the experimental abeta-induced neuronal damage model (ad model), and the ad model was infected with aav-hbdnf to explore neuroprotective effects of expression of bdnf. |
2008-07-02 |
2023-08-12 |
human |
| Marie Cahir, Tara C Ardis, Jennifer J Elliott, Christopher B Kelly, Gavin P Reynolds, Stephen J Coope. Acute tryptophan depletion does not alter central or plasma brain-derived neurotrophic factor in the rat. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 5. 2008-07-02. PMID:17719210. |
however, plasma or central bdnf protein levels in the hippocampus and midbrain were not significantly altered by atd. |
2008-07-02 |
2023-08-12 |
human |
| M A Steiner, K Wanisch, K Monory, G Marsicano, E Borroni, H Bächli, F Holsboer, B Lutz, C T Wotja. Impaired cannabinoid receptor type 1 signaling interferes with stress-coping behavior in mice. The pharmacogenomics journal. vol 8. issue 3. 2008-07-01. PMID:17684478. |
mrna expression of vesicular glutamate transporter type 1 was unaffected in cb1-/- mice, but mrna expression of brain-derived neurotrophic factor (bdnf) was reduced in the hippocampus. |
2008-07-01 |
2023-08-12 |
mouse |
| Michael H Donovan, Masahiro Yamaguchi, Amelia J Eisc. Dynamic expression of TrkB receptor protein on proliferating and maturing cells in the adult mouse dentate gyrus. Hippocampus. vol 18. issue 5. 2008-07-01. PMID:18240316. |
brain-derived neurotrophic factor (bdnf) is implicated in the regulation of adult hippocampal neurogenesis, presumably via its primary receptor, trkb. |
2008-07-01 |
2023-08-12 |
mouse |
| S Xapelli, L Bernardino, R Ferreira, S Grade, A P Silva, J R Salgado, C Cavadas, E Grouzmann, F R Poulsen, B Jakobsen, C R Oliveira, J Zimmer, J O Malv. Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: a role for microglia. The European journal of neuroscience. vol 27. issue 8. 2008-07-01. PMID:18412629. |
thus, an increase of ampa-receptor mediated neurodegeneration, in the mouse hippocampus, was prevented by neuroprotective pathways activated by npy receptors (y(1) and y(2)), which can be affected by bdnf released by microglia and neurons. |
2008-07-01 |
2023-08-12 |
mouse |
| F Miyajima, W Ollier, A Mayes, A Jackson, N Thacker, P Rabbitt, N Pendleton, M Horan, A Payto. Brain-derived neurotrophic factor polymorphism Val66Met influences cognitive abilities in the elderly. Genes, brain, and behavior. vol 7. issue 4. 2008-06-25. PMID:17973920. |
a large proportion of these reports suggest that the met allele, which results in reduced secretion of bdnf, impairs long-term memory as a direct consequence of its influence on hippocampal function but has little influence on working memory. |
2008-06-25 |
2023-08-12 |
human |
| Christopher A Chapleau, Maria E Carlo, Jennifer L Larimore, Lucas Pozzo-Mille. The actions of BDNF on dendritic spine density and morphology in organotypic slice cultures depend on the presence of serum in culture media. Journal of neuroscience methods. vol 169. issue 1. 2008-06-23. PMID:18242714. |
we have previously shown that brain-derived neurotrophin factor (bdnf) increases dendritic spine density and the proportion of stubby spines in apical dendrites of ca1 pyramidal neurons of hippocampal slice cultures maintained in serum-free media. |
2008-06-23 |
2023-08-12 |
Not clear |
| Song Li, Che Wang, Wei Wang, Huiping Dong, Peng Hou, Yiyuan Tan. Chronic mild stress impairs cognition in mice: from brain homeostasis to behavior. Life sciences. vol 82. issue 17-18. 2008-06-17. PMID:18402983. |
in addition, severe neuronal cell damage was found, as bromodeoxyuridine (brdu) positive cells and the expression of brain derived neurotrophic factor (bdnf) in dentate gyrus (dg) of hippocampus were decreased after 5 weeks cms procedure. |
2008-06-17 |
2023-08-12 |
mouse |
| Yuan Lu, Kimberly Christian, Bai L. BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory? Neurobiology of learning and memory. vol 89. issue 3. 2008-06-16. PMID:17942328. |
although the full complement of proteins mediating the long-lasting changes in synaptic efficacy have yet to be identified, several lines of evidence point to a crucial role for activity-induced brain-derived neurotrophic factor (bdnf) expression in generating sustained structural and functional changes at hippocampal synapses thought to underlie some forms of ltm. |
2008-06-16 |
2023-08-12 |
Not clear |
| Julio C Walz, Benício N Frey, Ana C Andreazza, Keila M Ceresér, Alice A Cacilhas, Samira S Valvassori, João Quevedo, Flávio Kapczinsk. Effects of lithium and valproate on serum and hippocampal neurotrophin-3 levels in an animal model of mania. Journal of psychiatric research. vol 42. issue 5. 2008-06-11. PMID:17512948. |
it has been demonstrated that lithium (li) and valproate (vpt), first line mood stabilizers, increase bdnf content in rat hippocampus and frontal cortex, which suggests that the regulation of neurotrophic factors might be associated with their pharmacological effects. |
2008-06-11 |
2023-08-12 |
rat |
| Staci D Bilbo, Ruth M Barrientos, Andrea S Eads, Alexis Northcutt, Linda R Watkins, Jerry W Rudy, Steven F Maie. Early-life infection leads to altered BDNF and IL-1beta mRNA expression in rat hippocampus following learning in adulthood. Brain, behavior, and immunity. vol 22. issue 4. 2008-06-04. PMID:17997277. |
early-life infection leads to altered bdnf and il-1beta mrna expression in rat hippocampus following learning in adulthood. |
2008-06-04 |
2023-08-12 |
rat |
| Staci D Bilbo, Ruth M Barrientos, Andrea S Eads, Alexis Northcutt, Linda R Watkins, Jerry W Rudy, Steven F Maie. Early-life infection leads to altered BDNF and IL-1beta mRNA expression in rat hippocampus following learning in adulthood. Brain, behavior, and immunity. vol 22. issue 4. 2008-06-04. PMID:17997277. |
here, we determined whether neonatal infection plus an immune challenge in adult rats is associated with impaired induction of brain-derived neurotrophic factor (bdnf) within the hippocampus (ca1, ca3, and dentate gyrus) following fear conditioning. |
2008-06-04 |
2023-08-12 |
rat |
| Staci D Bilbo, Ruth M Barrientos, Andrea S Eads, Alexis Northcutt, Linda R Watkins, Jerry W Rudy, Steven F Maie. Early-life infection leads to altered BDNF and IL-1beta mRNA expression in rat hippocampus following learning in adulthood. Brain, behavior, and immunity. vol 22. issue 4. 2008-06-04. PMID:17997277. |
taken together, these data indicate that early infection strongly influences the induction of il-1beta and bdnf within distinct regions of the hippocampus, which likely contribute to observed memory impairments in adulthood. |
2008-06-04 |
2023-08-12 |
rat |
| Fernanda Cechetti, Cíntia Fochesatto, Denise Scopel, Patrícia Nardin, Carlos Alberto Gonçalves, Carlos Alexandre Netto, Ionara Rodrigues Siqueir. Effect of a neuroprotective exercise protocol on oxidative state and BDNF levels in the rat hippocampus. Brain research. vol 1188. 2008-06-02. PMID:18021756. |
effect of a neuroprotective exercise protocol on oxidative state and bdnf levels in the rat hippocampus. |
2008-06-02 |
2023-08-12 |
rat |
| Fernanda Cechetti, Cíntia Fochesatto, Denise Scopel, Patrícia Nardin, Carlos Alberto Gonçalves, Carlos Alexandre Netto, Ionara Rodrigues Siqueir. Effect of a neuroprotective exercise protocol on oxidative state and BDNF levels in the rat hippocampus. Brain research. vol 1188. 2008-06-02. PMID:18021756. |
daily moderate intensity exercise (2 weeks of 20 min/day of treadmill training), which reduces damage to hippocampal slices from rats submitted to in vitro ischemia, did not modify oxidative stress parameters in the hippocampus nor the brain-derived neurotrophic factor (bdnf) levels in different brain regions. |
2008-06-02 |
2023-08-12 |
rat |
| Fernanda Cechetti, Cíntia Fochesatto, Denise Scopel, Patrícia Nardin, Carlos Alberto Gonçalves, Carlos Alexandre Netto, Ionara Rodrigues Siqueir. Effect of a neuroprotective exercise protocol on oxidative state and BDNF levels in the rat hippocampus. Brain research. vol 1188. 2008-06-02. PMID:18021756. |
the aim was to investigate whether the modulation of hippocampal oxidative status and/or brain bdnf content is involved in exercise-induced neuroprotection. |
2008-06-02 |
2023-08-12 |
rat |
| Fernanda Cechetti, Cíntia Fochesatto, Denise Scopel, Patrícia Nardin, Carlos Alberto Gonçalves, Carlos Alexandre Netto, Ionara Rodrigues Siqueir. Effect of a neuroprotective exercise protocol on oxidative state and BDNF levels in the rat hippocampus. Brain research. vol 1188. 2008-06-02. PMID:18021756. |
in addition, bdnf levels in different rat cerebral regions (hippocampus, cortex, striatum, and the cerebellum) were measured by elisa. |
2008-06-02 |
2023-08-12 |
rat |
| Tanel Mällo, Kadri Kõiv, Indrek Koppel, Karita Raudkivi, Ain Uustare, Ago Rinken, Tõnis Timmusk, Jaanus Harr. Regulation of extracellular serotonin levels and brain-derived neurotrophic factor in rats with high and low exploratory activity. Brain research. vol 1194. 2008-05-30. PMID:18177844. |
le-rats had higher levels of bdnf mrna in the pfc but not hippocampus. |
2008-05-30 |
2023-08-12 |
rat |
| A Bergström, M N Jayatissa, A Mørk, O Wibor. Stress sensitivity and resilience in the chronic mild stress rat model of depression; an in situ hybridization study. Brain research. vol 1196. 2008-05-30. PMID:18234161. |
in the ca3 of the ventral hippocampus, we found upregulation of brain-derived neurotrophic factor (bdnf) mrna in the cms resilient group indicating protective role of bdnf in stress. |
2008-05-30 |
2023-08-12 |
rat |
| Emi Kumamaru, Tadahiro Numakawa, Naoki Adachi, Yuki Yagasaki, Aiko Izumi, Madinyet Niyaz, Motoshige Kudo, Hiroshi Kunug. Glucocorticoid prevents brain-derived neurotrophic factor-mediated maturation of synaptic function in developing hippocampal neurons through reduction in the activity of mitogen-activated protein kinase. Molecular endocrinology (Baltimore, Md.). vol 22. issue 3. 2008-05-28. PMID:18096693. |
in this study, we investigated the effect of glucocorticoid (dexamethasone, dex) on synaptic maturation and function enhanced by bdnf in early developing hippocampal neurons. |
2008-05-28 |
2023-08-12 |
Not clear |