| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jamie S Church, Jane A M Bannish, Leighelle A Adrian, Kimberly Rojas Martinez, Asari Henshaw, Jared J Schwartze. Serum short chain fatty acids mediate hippocampal BDNF and correlate with decreasing neuroinflammation following high pectin fiber diet in mice. Frontiers in neuroscience. vol 17. 2023-05-01. PMID:37123365. |
serum short chain fatty acids mediate hippocampal bdnf and correlate with decreasing neuroinflammation following high pectin fiber diet in mice. |
2023-05-01 |
2023-08-14 |
mouse |
| Sakineh Alijanpour, Ameneh Rezayo. Activation of ventral hippocampal CB1 receptors inhibits ketamine-induced anxiogenic-like behavior: Alteration of BDNF/c-Fos levels in the mouse hippocampus. Brain research. 2023-04-30. PMID:37121426. |
also, the levels of bdnf and c-fos proteins in the mouse hippocampus were measured following the treatments. |
2023-04-30 |
2023-08-14 |
mouse |
| Sakineh Alijanpour, Ameneh Rezayo. Activation of ventral hippocampal CB1 receptors inhibits ketamine-induced anxiogenic-like behavior: Alteration of BDNF/c-Fos levels in the mouse hippocampus. Brain research. 2023-04-30. PMID:37121426. |
increased bdnf and c-fos levels in the hippocampus. |
2023-04-30 |
2023-08-14 |
mouse |
| Sakineh Alijanpour, Ameneh Rezayo. Activation of ventral hippocampal CB1 receptors inhibits ketamine-induced anxiogenic-like behavior: Alteration of BDNF/c-Fos levels in the mouse hippocampus. Brain research. 2023-04-30. PMID:37121426. |
hippocampal levels of bdnf and c-fos decreased after treatment with combined ketamine with acpa. |
2023-04-30 |
2023-08-14 |
mouse |
| Sakineh Alijanpour, Ameneh Rezayo. Activation of ventral hippocampal CB1 receptors inhibits ketamine-induced anxiogenic-like behavior: Alteration of BDNF/c-Fos levels in the mouse hippocampus. Brain research. 2023-04-30. PMID:37121426. |
this effect might be at least partially mediated by the alteration of bdnf and c-fos signaling in the hippocampus. |
2023-04-30 |
2023-08-14 |
mouse |
| Chengcheng Guo, Yang Yao, Chunchao Ma, Zhiyun Wan. High-intensity interval training improves cognitive impairment of vascular dementia rats by up-regulating expression of brain-derived neurotrophic factor in the hippocampus. Neuroreport. vol 34. issue 8. 2023-04-27. PMID:37104097. |
moreover, brain-derived neurotrophic factor (bdnf) expression level in the cerebral cortex and hippocampus tissue detected by western blot were significantly up-regulated in hiit group compared to sed group and mict group. |
2023-04-27 |
2023-08-14 |
rat |
| Mohammad Amin Rajizadeh, Mohammad Khaksari, Mohammad Abbas Bejeshk, Ladan Amirkhosravi, Elham Jafari, Zahra Jamalpoor, Akram Nezhad. The Role of Inhaled Estradiol and Myrtenol, Alone and in Combination, in Modulating Behavioral and Functional Outcomes Following Traumatic Experimental Brain Injury: Hemodynamic, Molecular, Histological and Behavioral Study. Neurocritical care. 2023-04-26. PMID:37100976. |
this study assessed the neuroprotective impacts of estradiol (e2), myrtenol (myr), and the combination of the two on the neurological outcome, hemodynamic parameters, learning and memory, brain-derived neurotrophic factor (bdnf) level, phosphoinositide 3-kinases (pi3k/akt) signaling, and inflammatory and oxidative factors in the hippocampus after tbi. |
2023-04-26 |
2023-08-14 |
Not clear |
| Yi Li, Zhongmin Fan, Qi Jia, Hongwei Ma, You Wu, Xiaofeng Guo, Lixia Du, Xi Wang, Wugang Hou, Zongping Fang, Xijing Zhan. Chaperone-mediated autophagy (CMA) alleviates cognitive impairment by reducing neuronal death in sepsis-associated encephalopathy (SAE). Experimental neurology. 2023-04-21. PMID:37085004. |
we further demonstrated that the overexpression of lamp2a in the hippocampus increased the expression of phosphorylated cyclic-amp response element binding protein (p-creb), brain-derived neurotrophic factor (bdnf) and b-cell lymphoma-2 (bcl-2), and suppressed the expression of cleaved caspase-3. |
2023-04-21 |
2023-08-14 |
mouse |
| Mariya I Zaichenko, Pavel Philenko, Viktoriya Sidorina, Grigory A Grigorya. Acute and Chronic Lipopolysaccharide-Induced Stress Changes Expression of Proinflammatory Cytokine Genes in the Rat Brain Region-Specifically and Affects Learning and Memory. Biochemistry. Biokhimiia. vol 88. issue 4. 2023-04-20. PMID:37080938. |
although chronic stress increased the levels of the tnf-α and il-1β mrna in the amygdala and hippocampus compared to the control groups, significance between the groups was only marginal and bdnf concentration did not differ from the control animals in any of the brain structures mentioned. |
2023-04-20 |
2023-08-14 |
rat |
| Mariya I Zaichenko, Pavel Philenko, Viktoriya Sidorina, Grigory A Grigorya. Acute and Chronic Lipopolysaccharide-Induced Stress Changes Expression of Proinflammatory Cytokine Genes in the Rat Brain Region-Specifically and Affects Learning and Memory. Biochemistry. Biokhimiia. vol 88. issue 4. 2023-04-20. PMID:37080938. |
in total, the most pronounced molecular-biochemical changes occurred in the amygdala and hippocampus, where increase of the expression of the tnf-α and il-1β interleukins mrnas were observed in the animals under acute and chronic lps-induced stress and no changes in the bdnf mrna concentration were observed in the frontal lobe. |
2023-04-20 |
2023-08-14 |
rat |
| Caio Matheus Santos da Silva Calado, Raul Manhães-de-Castro, Sabrina da Conceição, Pereira, Vanessa da Silva Souza, Diego Bulcão Visco, Beatriz Souza de Silveira, Sandra Lopes de Souza, Ana Elisa Toscan. Therapeutic advances for treating memory impairments in perinatal brain injuries with implications for cerebral palsy: A systematic review and meta-analysis of preclinical studies. Experimental neurology. 2023-04-17. PMID:37068620. |
some studies reported that regions of the hippocampus such as the dentate gyrus and cornu ammonis 1 were impaired in cp, noting an increase in oxidative stress enzymes and pro-inflammatory cytokines, associated with a reduction in bdnf and neurogenesis levels. |
2023-04-17 |
2023-08-14 |
Not clear |
| Lu Ji, Rong-Jie Jin, Lin L. Platelet-rich Plasma Improves Radiotherapy-induced Emotional Disorder and Cognitive Dysfunction, Neuroinflammation in Aged Rats by Inhibiting the Activation of NLRP3 Inflammasomes. Neurochemical research. 2023-04-12. PMID:37043084. |
besides, immunohistochemistry was used to detect the expression of microglial marker protein iba-1 in rat hippocampus; enzyme linked immunosorbent assay (elisa) to examine the levels of pro-inflammatory cytokines tumor necrosis factor-alpha (tnf-α), interleukin (il)-1 beta (il-1β), il-18, and monocyte chemoattractant protein 1 (mcp-1) in rat hippocampus; real-time quantitative reverse transcription pcr (qrt-pcr) and western blot to measure the levels of neurotrophic factors brain-derived neurotrophic factor (bdnf), tropomyosin-related kinase b receptor (trkb), and nerve growth factor (ngf) in rat hippocampus; and western blot also to observe the protein expression levels of nod-like receptor protein 3 (nlrp3), caspase-1, apoptosis-associated speck-like protein containing a card (asc), and il-1β in rat hippocampus. |
2023-04-12 |
2023-08-14 |
rat |
| Reine Khoury, Joelle Saad, Vanessa Jabre, Litsa Maria Ghayad, Mohamad Khalifeh, Rouba Houbeika, Perla El Ahmad, Amar Mezher, Diala El Masri, Zena Haddad, Fady Eid, Nour Barmo, Patrick Nasrallah, Sama F Sleiman, Joseph S Stepha. Autophagy regulates the release of exercise factors and their beneficial effects on spatial memory recall. Heliyon. vol 9. issue 4. 2023-04-07. PMID:37025840. |
the positive effects of exercise are mediated by circulatory factors that predominantly increase brain derived neurotrophic factor (bdnf) signaling in the hippocampus. |
2023-04-07 |
2023-08-14 |
Not clear |
| b' Sinan Saral, Atilla Top\\xc3\\xa7u, Mehmet Alkanat, Tolga Mercantepe, Zafer \\xc5\\x9eahin, Kerimali Aky\\xc4\\xb1ld\\xc4\\xb1z, Kader Semra Karata\\xc5\\x9f, Lamiye Y\\xc4\\xb1ld\\xc4\\xb1z, Levent T\\xc3\\xbcmkaya, Zihni A\\xc3\\xa7ar Yaz\\xc4\\xb1c\\xc4\\xb. Agomelatine attenuates cisplatin-induced cognitive impairment via modulation of BDNF/TrkB signaling in rat hippocampus. Journal of chemical neuroanatomy. 2023-03-31. PMID:37001681.' |
after behavioral tests, rats were euthanized and bdnf, tnf, il-1β, mda and gsh levels were measured in hippocampal homegenates by elisa. |
2023-03-31 |
2023-08-14 |
rat |
| b' Sinan Saral, Atilla Top\\xc3\\xa7u, Mehmet Alkanat, Tolga Mercantepe, Zafer \\xc5\\x9eahin, Kerimali Aky\\xc4\\xb1ld\\xc4\\xb1z, Kader Semra Karata\\xc5\\x9f, Lamiye Y\\xc4\\xb1ld\\xc4\\xb1z, Levent T\\xc3\\xbcmkaya, Zihni A\\xc3\\xa7ar Yaz\\xc4\\xb1c\\xc4\\xb. Agomelatine attenuates cisplatin-induced cognitive impairment via modulation of BDNF/TrkB signaling in rat hippocampus. Journal of chemical neuroanatomy. 2023-03-31. PMID:37001681.' |
on the other hand, agomelatine treatment elevated cisplatin-suppressed hippocampal bdnf levels. |
2023-03-31 |
2023-08-14 |
rat |
| In-Seo Lee, Ga-Young Choi, Inturu Sreelatha, Ji-Won Yoon, Suk-Hee Youn, Sungho Maeng, Ji-Ho Par. Effect of Sinapic Acid on Scopolamine-Induced Learning and Memory Impairment in SD Rats. Brain sciences. vol 13. issue 3. 2023-03-29. PMID:36979237. |
in addition, sinapic acid weakened the inhibition of the brain-derived neurotrophic factor (bdnf), tropomyosin receptor kinase b (trkb) and the activation of prostaglandin-endoperoxide synthase 2 (cox-2) and interleukin 1 beta (il-1β) induced by scopolamine in the hippocampus. |
2023-03-29 |
2023-08-14 |
rat |
| Lan Wei, Qiang Tao, Minmin Yao, Zhimeng Zhao, Shengjin G. Caloric Restriction Can Ameliorate Postoperative Cognitive Dysfunction by Upregulating the Expression of Sirt1, MeCP2 and BDNF in the Hippocampal CA1 Region of Aged C57BL/6 Mice. Brain sciences. vol 13. issue 3. 2023-03-29. PMID:36979272. |
by using western blot and immunofluorescence, the expression of sirt1, mecp2, and bdnf in the hippocampus and hippocampal ca1 region was quantified. |
2023-03-29 |
2023-08-14 |
mouse |
| Lan Wei, Qiang Tao, Minmin Yao, Zhimeng Zhao, Shengjin G. Caloric Restriction Can Ameliorate Postoperative Cognitive Dysfunction by Upregulating the Expression of Sirt1, MeCP2 and BDNF in the Hippocampal CA1 Region of Aged C57BL/6 Mice. Brain sciences. vol 13. issue 3. 2023-03-29. PMID:36979272. |
sirt1, mecp2, and bdnf expression in the hippocampus and ca1 region in the hippocampus of the alc and crc groups of mice were correlated with cognitive improvement. |
2023-03-29 |
2023-08-14 |
mouse |
| Lan Wei, Qiang Tao, Minmin Yao, Zhimeng Zhao, Shengjin G. Caloric Restriction Can Ameliorate Postoperative Cognitive Dysfunction by Upregulating the Expression of Sirt1, MeCP2 and BDNF in the Hippocampal CA1 Region of Aged C57BL/6 Mice. Brain sciences. vol 13. issue 3. 2023-03-29. PMID:36979272. |
in conclusion, cr could enhance the postoperative cognitive function in aged mice, most likely by increasing the expression of sirt1, mecp2, and bdnf in the ca1 region of the hippocampus. |
2023-03-29 |
2023-08-14 |
mouse |
| Lamia M Hafez, Hebatallah Mohammed Aboudeya, Noura A Matar, Ashraf S El-Sebeay, Azhar Mohamed Nomair, Shaymaa Ali El-Hamshary, Hanan Mohamed Nomeir, Fawziya A R Ibrahi. Ameliorative effects of zinc supplementation on cognitive function and hippocampal leptin signaling pathway in obese male and female rats. Scientific reports. vol 13. issue 1. 2023-03-28. PMID:36977735. |
hfd feeding also reduced brain-derived neurotrophic factor (bdnf) levels and increased acetylcholinesterase (ache) activity in the hippocampus of both sexes. |
2023-03-28 |
2023-08-14 |
rat |