| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zijuan Zhang, Ziyang Yu, Ye Yuan, Jing Yang, Shijie Wang, He Ma, Li Hao, Jinlian Ma, Zhonghua Li, Zhenqiang Zhang, Christian Hölsche. Cholecystokinin Signaling can Rescue Cognition and Synaptic Plasticity in the APP/PS1 Mouse Model of Alzheimer's Disease. Molecular neurobiology. 2023-05-29. PMID:37247071. |
our study found that the cck analogue could effectively improve spatial learning and memory, enhance synaptic plasticity in the hippocampus, normalize synapse numbers and morphology and the levels of key synaptic proteins, up-regulate the pi3k/akt signaling pathway and normalize pka, creb, bdnf and trkb receptor levels in app/ps1 mice. |
2023-05-29 |
2023-08-14 |
mouse |
| Jie Zheng, Feng Yang, Pu-Wei Yuan, Jing-Jie Fan, Xiao-Hui Zheng, Rui Zhu, Yang-le L. [Effect of electroacupuncture on the expression of Iba-1 in spinal dorsal horn and hippocampus of chronic pain rats with knee osteoarthritis]. Zhen ci yan jiu = Acupuncture research. vol 48. issue 5. 2023-05-29. PMID:37247855. |
to observe the effect of electroacupuncture(ea) on pain-ralated behaviors, morphology of hippocampus, concentrations of inflammatory cytokines and expression of ionized calcium binding adapter molecule 1(iba-1) in dorsal horn of the spinal cord and the hippocampus, and brain-derived neurotrophic factor (bdnf) in hippocampus of rats with knee osteoarthritis (koa), so as to explore the mechanism of ea in improving chronic pain of koa. |
2023-05-29 |
2023-08-14 |
rat |
| Tatiana Ilchibaeva, Anton Tsybko, Marina Lipnitskaya, Dmitry Eremin, Kseniya Milutinovich, Vladimir Naumenko, Nina Popov. Brain-Derived Neurotrophic Factor (BDNF) in Mechanisms of Autistic-like Behavior in BTBR Mice: Crosstalk with the Dopaminergic Brain System. Biomedicines. vol 11. issue 5. 2023-05-27. PMID:37239153. |
for this reason, the aim of our study was to compare the effects of either the acute intracerebroventricular administration of a recombinant bdnf protein or hippocampal adeno-associated-virus-mediated bdnf overexpression on autistic-like behavior and expression of key da-related and bdnf-related genes in btbr mice (a widely recognized model of autism). |
2023-05-27 |
2023-08-14 |
mouse |
| Sakshi M Kothawade, Harpal Singh Buttar, Hardeep Singh Tuli, Ginpreet Kau. Therapeutic potential of flavonoids in the management of obesity-induced Alzheimer's disease: an overview of preclinical and clinical studies. Naunyn-Schmiedeberg's archives of pharmacology. 2023-05-25. PMID:37231172. |
furthermore, flavonoids like curcumin, resveratrol, epigallocatechin-3-gallate, morin, delphinidins, quercetin, luteolin, and oleocanthal have shown to cause significant reductions in interleukin-1β, increase bdnf levels, stimulate hippocampal neurogenesis and synapse formation, and ultimately prevent the loss of neurons in the brain. |
2023-05-25 |
2023-08-14 |
Not clear |
| Xufei Zhang, Xianhao Jia, Shengnan Wang, Jinge Xin, Ning Sun, Yanyan Wang, Xingting Zhang, Zhiqiang Wan, Jing Fan, Hao Li, Yang Bai, Xueqin Ni, Yongmei Huang, Hesong Wang, Hailin M. Disrupted gut microbiota aggravates spatial memory dysfunction induced by high altitude exposure: A link between plateau environment and microbiome-gut-brain axis. Ecotoxicology and environmental safety. vol 259. 2023-05-24. PMID:37224779. |
the results showed that spatial memory dysfunction induced by the high-altitude environment was aggravated by antibiotic treatment, manifesting as lowered escape latency and hippocampal memory-related proteins (bdnf and psd-95). |
2023-05-24 |
2023-08-14 |
mouse |
| Chiara Criscuolo, Elissavet Chartampila, Stephen D Ginsberg, Helen E Scharfma. Stability of dentate gyrus granule cell mossy fiber BDNF protein expression with age and resistance of granule cells to Alzheimer's disease neuropathology in a mouse model. bioRxiv : the preprint server for biology. 2023-05-23. PMID:37214931. |
hippocampal bdnf has been implicated alzheimer's disease (ad) because hippocampal levels in ad patients and ad animal models are consistently downregulated, suggesting that reduced bdnf contributes to ad. |
2023-05-23 |
2023-08-14 |
mouse |
| Chiara Criscuolo, Elissavet Chartampila, Stephen D Ginsberg, Helen E Scharfma. Stability of dentate gyrus granule cell mossy fiber BDNF protein expression with age and resistance of granule cells to Alzheimer's disease neuropathology in a mouse model. bioRxiv : the preprint server for biology. 2023-05-23. PMID:37214931. |
however, the location where hippocampal bdnf protein is most highly expressed, the mossy fiber (mf) axons of dentate gyrus (dg) granule cells (gcs), has been understudied, and never in controlled |
2023-05-23 |
2023-08-14 |
mouse |
| Hamed Hajizadeh Tekmeh, Birgul Vanizor Kural, Sevil Kör, Meltem Arıkan Malkoç, Esin Yuluğ, Abdulkadir Kutlu, İsmail Abidin, Asım Ore. How does l-theanine treatment affect the levels of serum and hippocampal BDNF, insulin and adipocytokines in diabetic rats? Biochemical and biophysical research communications. vol 667. 2023-05-21. PMID:37210871. |
how does l-theanine treatment affect the levels of serum and hippocampal bdnf, insulin and adipocytokines in diabetic rats? |
2023-05-21 |
2023-08-14 |
rat |
| Esra Toplu Uslu, Murat Mengi, Elmas Beyazyüz, Aliye Çelikkol, Yakup Albayra. The effects of sigma-1 agonist fluvoxamine on experimental induced tardive dyskinesia model in rats. Progress in neuro-psychopharmacology & biological psychiatry. 2023-05-17. PMID:37196751. |
subsequently, samples were collected from the hippocampus, striatum, and frontal lobe tissues of the rats, and bdnf, ngf, sod, and mda levels were measured. |
2023-05-17 |
2023-08-14 |
rat |
| Esra Toplu Uslu, Murat Mengi, Elmas Beyazyüz, Aliye Çelikkol, Yakup Albayra. The effects of sigma-1 agonist fluvoxamine on experimental induced tardive dyskinesia model in rats. Progress in neuro-psychopharmacology & biological psychiatry. 2023-05-17. PMID:37196751. |
furthermore, sod levels in the hippocampus, as well as bdnf, ngf, and sod levels in the striatum of the haloperidol+fluvoxamine group were significantly higher than those observed in the haloperidol group. |
2023-05-17 |
2023-08-14 |
rat |
| Chuanxi Tang, Mengting Liu, Zihang Zhou, Hao Li, Chenglin Yang, Li Yang, Jie Xian. Treadmill Exercise Alleviates Cognition Disorder by Activating the FNDC5: Dual Role of Integrin αV/β5 in Parkinson's Disease. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37175535. |
the direct protective effect of fndc5 is achieved by promoting the secretion of bdnf in the hippocampal neurons via binding the integrin αvβ5 receptor, thereby improving synaptic plasticity. |
2023-05-14 |
2023-08-14 |
mouse |
| Jing Wang, Jianxing Wang, Yulai Wang, Yiwen Chai, Haochen Li, Deyang Miao, Honggui Liu, Jianhong Li, Jun Ba. Music with Different Tones Affects the Development of Brain Nerves in Mice in Early Life through BDNF and Its Downstream Pathways. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37175826. |
in addition, the number of dendritic spines and the number of dendritic spines per unit length were significantly higher than those in group c, and the expressions of synaptic plasticity proteins (syp and psd95) were also significantly elevated over those in group c. compared with group c, the expression levels of bdnf, trkb, creb, pi3k, akt, gs3kβ, plcγ1, pkc, dag, erk and mapk genes and proteins in the hippocampus and prefrontal cortex of mice in the music groups were up-regulated, suggesting that different tones of music could regulate neural development through bdnf and its downstream pathways. |
2023-05-14 |
2023-08-14 |
mouse |
| Kazuki Nakanishi, Kosuke Norimatsu, Akira Tani, Teruki Matsuoka, Ryoma Matsuzaki, Syogo Kakimoto, Nao Nojima, Yuta Tachibe, Yuki Kato, Masaki Inadome, Riho Kitazato, Shotaro Otsuka, Seiya Takada, Megumi Sumizono, Harutoshi Sakakim. Effects of early exercise intervention and exercise cessation on neuronal loss and neuroinflammation in a senescence-accelerated mouse prone 8. Neuroscience letters. 2023-05-14. PMID:37182575. |
age-related cognitive decline was prevented in the lt-ex group compared with the no-ex group through the suppression of neuronal loss, enhanced brain-derived neurotrophic factor (bdnf), and inhibition of neuroinflammation corresponding to reduced m1 and increased m2 microglia in the hippocampus. |
2023-05-14 |
2023-08-14 |
mouse |
| Minghao Li, Li Wang, Siyuan Guo, Nan Huang, Heng A. Cordycepin buffers anisomycin-induced fear memory deficit by restoring hippocampal BDNF. Biochemical and biophysical research communications. vol 665. 2023-05-08. PMID:37156049. |
cordycepin buffers anisomycin-induced fear memory deficit by restoring hippocampal bdnf. |
2023-05-08 |
2023-08-14 |
Not clear |
| Minghao Li, Li Wang, Siyuan Guo, Nan Huang, Heng A. Cordycepin buffers anisomycin-induced fear memory deficit by restoring hippocampal BDNF. Biochemical and biophysical research communications. vol 665. 2023-05-08. PMID:37156049. |
we observed that cordycepin was able to attenuate these deficits and restore bdnf levels in the hippocampus. |
2023-05-08 |
2023-08-14 |
Not clear |
| Minghao Li, Li Wang, Siyuan Guo, Nan Huang, Heng A. Cordycepin buffers anisomycin-induced fear memory deficit by restoring hippocampal BDNF. Biochemical and biophysical research communications. vol 665. 2023-05-08. PMID:37156049. |
our findings provide the first evidence that cordycepin can prevent anisomycin-induced memory deficits by regulating bdnf expression in the hippocampus. |
2023-05-08 |
2023-08-14 |
Not clear |
| Ka Wai Chan, Jennifer Hebert, Daniel Radford-Smith, Daniel C Anthony, Philip Wj Burne. Live or heat-killed probiotic administration reduces anxiety and central cytokine expression in BALB/c mice, but differentially alters brain neurotransmitter gene expression. Neuropharmacology. 2023-05-07. PMID:37150398. |
furthermore, probiotic administration elevated hippocampal bdnf and decreased gaba |
2023-05-07 |
2023-08-14 |
mouse |
| Ye Ji Lee, Ye Ji Jeong, Eun Ji Kang, Beom Seok Kang, Song Hee Lee, You Jin Kim, Seong Su Kang, Sang Won Suh, Eun Hee Ah. GAP-43 closely interacts with BDNF in hippocampal neurons and is associated with Alzheimer's disease progression. Frontiers in molecular neuroscience. vol 16. 2023-05-05. PMID:37143467. |
gap-43 closely interacts with bdnf in hippocampal neurons and is associated with alzheimer's disease progression. |
2023-05-05 |
2023-08-14 |
Not clear |
| Bingjie Liu, Yuxin Du, Chang Xu, Qingzhen Liu, Lidong Zhan. Antidepressant effects of repeated s-ketamine administration as NMDAR Antagonist: Involvement of CaMKIIα and mTOR signaling in the hippocampus of CUMS mice. Brain research. 2023-05-05. PMID:37146745. |
the protein expressions of glun1, glun2a, glun2b, glur1, camkiiα, phosphorylated camkiiα (p-camkiiα), bdnf, trkb, phosphorylated trkb (p-trkb), mtor, and phosphorylated mtor (p-mtor) as well as modification of synaptic ultrastructure was identified in hippocampal tissues. |
2023-05-05 |
2023-08-14 |
mouse |
| K T Meyers, C C Damphousse, A B Ozols, J M Campbell, J M Newbern, C Hu, D F Marrone, A L Gallitan. Serial electroconvulsive Seizure alters dendritic complexity and promotes cellular proliferation in the mouse dentate gyrus; a role for Egr3. Brain stimulation. 2023-05-05. PMID:37146791. |
we have previously shown that this upregulation of bdnf fails to occur in the hippocampus of mice lacking the ieg egr3. |
2023-05-05 |
2023-08-14 |
mouse |