Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Jingyuan Ma, Feng Xiong, Zhouru Li, Guokai Dong, Xiaoming Sun, Wenjiang Yin, Hongxing Ca. The effect of chronic alcohol exposure on spatial memory and BDNF-TrkB- PLCγ1 signaling in the hippocampus of male and female mice. Heliyon. vol 9. issue 6. 2023-06-12. PMID:37303582. |
after 4 weeks of intermittent access to 20% alcohol, memory impairment in both male and female mice was evaluated using the morris water maze and the expression of bdnf, trkb, phosphorylation of plcγ1 (p-plcγ1) and plcγ1 in the hippocampus was examined using western blot. |
2023-06-12 |
2023-08-14 |
mouse |
Jingyuan Ma, Feng Xiong, Zhouru Li, Guokai Dong, Xiaoming Sun, Wenjiang Yin, Hongxing Ca. The effect of chronic alcohol exposure on spatial memory and BDNF-TrkB- PLCγ1 signaling in the hippocampus of male and female mice. Heliyon. vol 9. issue 6. 2023-06-12. PMID:37303582. |
furthermore, after 4 weeks 20% alcohol exposure, we found significantly decreased expression levels of bdnf in the hippocampus of female mice but increased levels in male mice. |
2023-06-12 |
2023-08-14 |
mouse |
Jingyuan Ma, Feng Xiong, Zhouru Li, Guokai Dong, Xiaoming Sun, Wenjiang Yin, Hongxing Ca. The effect of chronic alcohol exposure on spatial memory and BDNF-TrkB- PLCγ1 signaling in the hippocampus of male and female mice. Heliyon. vol 9. issue 6. 2023-06-12. PMID:37303582. |
these findings suggest that chronic alcohol exposure may induce spatial memory impairment in both sexes and opposite changes in expression of bdnf and p-plcγ1 in the hippocampus of males and females. |
2023-06-12 |
2023-08-14 |
mouse |
Jana Tchekalarova, Desislava Krushovlieva, Petya Ivanova, Lidia Kortensk. Spontaneously hypertensive rats vs. Wistar Kyoto and Wistar rats: an assessment of anxiety, motor activity, memory performance, and seizure susceptibility. Physiology & behavior. 2023-06-12. PMID:37308045. |
in addition, the role of brain-derived neurotrophic factor (bdnf) in the hippocampus on cognitive behavior and seizure susceptibility in the three strains was evaluated. |
2023-06-12 |
2023-08-14 |
rat |
Jana Tchekalarova, Desislava Krushovlieva, Petya Ivanova, Lidia Kortensk. Spontaneously hypertensive rats vs. Wistar Kyoto and Wistar rats: an assessment of anxiety, motor activity, memory performance, and seizure susceptibility. Physiology & behavior. 2023-06-12. PMID:37308045. |
control shr had lower bdnf expression in the hippocampus compared to wistar rats. |
2023-06-12 |
2023-08-14 |
rat |
Jana Tchekalarova, Desislava Krushovlieva, Petya Ivanova, Lidia Kortensk. Spontaneously hypertensive rats vs. Wistar Kyoto and Wistar rats: an assessment of anxiety, motor activity, memory performance, and seizure susceptibility. Physiology & behavior. 2023-06-12. PMID:37308045. |
the results suggest wistar rats as a more appropriate control of shr than wky rats for studying memory responses mediated by bdnf in the hippocampus. |
2023-06-12 |
2023-08-14 |
rat |
Jana Tchekalarova, Desislava Krushovlieva, Petya Ivanova, Lidia Kortensk. Spontaneously hypertensive rats vs. Wistar Kyoto and Wistar rats: an assessment of anxiety, motor activity, memory performance, and seizure susceptibility. Physiology & behavior. 2023-06-12. PMID:37308045. |
the higher vulnerability to seizures in wistar and wky rats compared to shr might be linked to ptz-induced decreased expression of bdnf in the hippocampus. |
2023-06-12 |
2023-08-14 |
rat |
Manuela Dicarlo, Patrizia Pignataro, Roberta Zerlotin, Clelia Suriano, Chiara Zecca, Maria Teresa Dell'Abate, Giuseppina Storlino, Angela Oranger, Lorenzo Sanesi, Giorgio Mori, Maria Grano, Graziana Colaianni, Silvia Colucc. Short-Term Irisin Treatment Enhanced Neurotrophin Expression Differently in the Hippocampus and the Prefrontal Cortex of Young Mice. International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298063. |
we found significantly increased mrna levels of nerve growth factor (ngf) and fibroblast growth factor 2 (fgf-2) in the hippocampus and brain-derived growth factor (bdnf) in the pfc. |
2023-06-11 |
2023-08-14 |
mouse |
Elena Chiavacci, Sara Bagnoli, Alessandro Cellerino, Eva Terzibasi Tozzin. Distribution of Brain-Derived Neurotrophic Factor in the Brain of the Small-Spotted Catshark International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298444. |
among the neurotrophins, brain-derived neurotrophic factor (bdnf) has the highest expression and is expressed in mammals by specific cells throughout the brain, with particularly high expression in the hippocampus and cerebral cortex. |
2023-06-11 |
2023-08-14 |
Not clear |
Maria Pina Serra, Francesco Sanna, Marianna Boi, Marcello Trucas, Alberto Fernández-Teruel, Maria Giuseppa Corda, Osvaldo Giorgi, Marina Quart. Effects of Tail Pinch on BDNF and trkB Expression in the Hippocampus of Roman Low- (RLA) and High-Avoidance (RHA) Rats. International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298449. |
effects of tail pinch on bdnf and trkb expression in the hippocampus of roman low- (rla) and high-avoidance (rha) rats. |
2023-06-11 |
2023-08-14 |
human |
Maria Pina Serra, Francesco Sanna, Marianna Boi, Marcello Trucas, Alberto Fernández-Teruel, Maria Giuseppa Corda, Osvaldo Giorgi, Marina Quart. Effects of Tail Pinch on BDNF and trkB Expression in the Hippocampus of Roman Low- (RLA) and High-Avoidance (RHA) Rats. International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298449. |
in this article, we describe the effects of tail pinch (tp), a mild acute stressor, on the levels of brain-derived neurotrophic factor (bdnf) and its tyrosine kinase receptor b (trkb) proteins in the hippocampus (hc) of the outbred roman high- (rha) and low-avoidance (rla) rats, one of the most validated genetic models for the study of fear/anxiety- and stress-related behaviors. |
2023-06-11 |
2023-08-14 |
human |
Bing Xue, Yin-Yan Ma, Jie-Ying Zhu, Yan Mu, Yong-Hui Li, Fang Shen, Jing Liang, Jian-Jun Zhan. Chronic social comparison elicits depression- and anxiety-like behaviors and alterations in brain-derived neurotrophic factor expression in male rats. Animal cognition. 2023-06-11. PMID:37302101. |
this model was subsequently used to examine the effects of the differential environment of a partner on depression- and anxiety-like behaviors in male rats, as well as to assess the changes in serum, medial prefrontal cortex (mpfc), and dorsal hippocampus brain-derived neurotrophic factor (bdnf) levels induced by long-term social comparison. |
2023-06-11 |
2023-08-14 |
human |
Bing Xue, Yin-Yan Ma, Jie-Ying Zhu, Yan Mu, Yong-Hui Li, Fang Shen, Jing Liang, Jian-Jun Zhan. Chronic social comparison elicits depression- and anxiety-like behaviors and alterations in brain-derived neurotrophic factor expression in male rats. Animal cognition. 2023-06-11. PMID:37302101. |
further, rats whose partners were exposed to one enriched environment for 31 days showed lower bdnf levels in the mpfc and dorsal hippocampus, but not following partner exposure for 14 days. |
2023-06-11 |
2023-08-14 |
human |
Sara Florén Lind, Frida Stam, Sofia Zelleroth, Evelina Meurling, Andreas Frick, Alfhild Grönblad. Acute caffeine differently affects risk-taking and the expression of BDNF and of adenosine and opioid receptors in rats with high or low anxiety-like behavior. Pharmacology, biochemistry, and behavior. 2023-06-11. PMID:37302662. |
thus, the aim of this study was to investigate general behavior, risk-taking, and anxiety-like behavior, as well as mrna expression (adenosine a2a and a1, dopamine d2, and, μ, κ, δ opioid, receptors, bdnf, c-fos, igf-1) in amygdala, caudate putamen, frontal cortex, hippocampus, hypothalamus, after an acute dose of caffeine. |
2023-06-11 |
2023-08-14 |
rat |
Sara Florén Lind, Frida Stam, Sofia Zelleroth, Evelina Meurling, Andreas Frick, Alfhild Grönblad. Acute caffeine differently affects risk-taking and the expression of BDNF and of adenosine and opioid receptors in rats with high or low anxiety-like behavior. Pharmacology, biochemistry, and behavior. 2023-06-11. PMID:37302662. |
the results demonstrated that the high anxiety-like behavior rats treated with caffeine spent less time in risk areas of the mcsf and resituated towards the sheltered areas, a behavior accompanied by lower mrna expression of adenosine a2a receptors in caudate putamen and increased bdnf expression in hippocampus. |
2023-06-11 |
2023-08-14 |
rat |
Naomi Lomeli, Diana C Pearre, Maureen Cruz, Kaijun Di, Daniela A Bot. Cisplatin Induces BDNF Downregulation in Middle-Aged Female Rat Model while BDNF Enhancement Attenuates Cisplatin Neurotoxicity. bioRxiv : the preprint server for biology. 2023-06-09. PMID:37293048. |
our previous crci rodent studies have shown that cisplatin reduces hippocampal neurogenesis and bdnf expression and increases hippocampal apoptosis, which is associated with cognitive impairments. |
2023-06-09 |
2023-08-14 |
rat |
Shabnam Radbakhsh, Alexandra E Butler, Seyed Adel Moallem, Amirhossein Sahebka. The effects of curcumin on Brain-Derived Neurotrophic Factor expression in neurodegenerative disorders. Current medicinal chemistry. 2023-06-06. PMID:37278037. |
changes in bdnf expression might be associated with neuropsychiatric diseases, particularly in structures important for memory processes, including the hippocampus and parahippocampal areas. |
2023-06-06 |
2023-08-14 |
human |
Amin Hassanshahi, Mahyar Janahmadi, Moazamehosadat Razavinasab, Mehran Ilaghi, Kristi A Kohlmeier, Elham Hassanshahi, Mohammad Shaban. Administration of agmatine prior to physical or psychological stress in pregnant mice ameliorates behavioural and cognitive deficits in female offspring. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2023-06-03. PMID:37269159. |
neither ps nor agmatine treatment affected the mrna expression level of hippocampal brain-derived neurotrophic factor (bdnf) or tyrosine hydroxylase (th) in the ventral tegmental area (vta). |
2023-06-03 |
2023-08-14 |
mouse |
Seda Kose, Meltem Donmez Kutlu, Samet Kara, Sait Polat, Kubra Akilliogl. Investıgatıon of the protectıve effect of long-term exercıse on molecular pathways and behavıours ın scopolamıne ınduced alzheımer's dısease-lıke condıtıon. Brain research. 2023-06-03. PMID:37269967. |
hippocampus and prefrontal cortex of mice were isolated, and levels of bdnf, trkb, and p-gsk3ß |
2023-06-03 |
2023-08-14 |
mouse |
Hee Ra Park, Heeeun Lee, Won-Kyung Cho, Jin Yeul M. Pro-neurogenic effects of Lilii Bulbus on hippocampal neurogenesis and memory. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 164. 2023-06-02. PMID:37267636. |
we found that welb has a pro-neurogenic effect by increasing the activation of brain-derived neurotrophic factor (bdnf)/camp response element-binding protein (creb) and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (mek/erk) in the hippocampus. |
2023-06-02 |
2023-08-14 |
mouse |