Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Samira S Valvassori, Richard T da Rosa, Gustavo C Dal-Pont, Roger B Varela, Gustavo A Mastella, Thiani Daminelli, Gabriel R Fries, João Quevedo, Alexandra I Zugn. Haloperidol alters neurotrophic factors and epigenetic parameters in an animal model of schizophrenia induced by ketamine. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2023-08-27. PMID:37635268. |
the activity of dna methyltransferase (dnmt), histone deacetylase (hdac), and histone acetyltransferase and levels of brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf), neurotrophin-3 (nt-3), and glial-derived neurotrophic factor (gdnf) were evaluated in the frontal cortex, hippocampus, and striatum. |
2023-08-27 |
2023-09-07 |
rat |
Akanksha Kushwaha, Mahendra Kumar Thaku. Suv39h1 Silencing Recovers Memory Decline in Scopolamine-Induced Amnesic Mouse Model. Molecular neurobiology. 2023-08-25. PMID:37626270. |
suv39h1 silencing in amnesic mice reduced h3k9me3 levels at the neuronal iegs (arc and bdnf) promoter, increased the expression of arc and bdnf in the hippocampus, and improved recognition memory. |
2023-08-25 |
2023-09-07 |
mouse |
Yujuan Zhao, You Kang, Zijian Zhao, Ge Yang, Yansong Gao, Lei Gao, Chao Wang, Shengyu L. Lacticaseibacillus rhamnosus TF318 prevents depressive behavior in rats by inhibiting HPA-axis hyperactivity and upregulating BDNF expression. Neuroscience letters. 2023-08-24. PMID:37619699. |
a marked increase was observed in the hippocampal concentration of brain-derived neurotrophic factor (bdnf), a change that may have involved the cyclic adenosine monophosphate (camp)/camp response element-binding/bdnf signaling pathway. |
2023-08-24 |
2023-09-07 |
rat |
Aanchal Aggarwal, Binduma Yadav, Nishtha Sharma, Raminder Kaur, Vikas Rish. Disruption of histone acetylation homeostasis triggers cognitive dysfunction in experimental diabetes. Neurochemistry international. 2023-08-20. PMID:37598859. |
reduced h3k9/14 and h4k12 acetylation paralleled transcriptional repression of memory-related markers bdnf, syp, and psd-95 in the cortex and hippocampus of t1d and t2d. |
2023-08-20 |
2023-09-07 |
mouse |
Atefeh Bakhtazad, Afsaneh Asgari Taei, Fatemeh Parvizi, Mehdi Kadivar, Maryam Farahmandfa. Repeated Pre-exposure to Morphine Inhibited the Amnesic Effect of Ethanol on Spatial Memory: Involvement of CaMKII and BDNF. Alcohol (Fayetteville, N.Y.). 2023-08-19. PMID:37597575. |
also, we assessed how these drug-exposures influence the expression level of camkii and bdnf in the hippocampus and amygdala. |
2023-08-19 |
2023-09-07 |
rat |
Atefeh Bakhtazad, Afsaneh Asgari Taei, Fatemeh Parvizi, Mehdi Kadivar, Maryam Farahmandfa. Repeated Pre-exposure to Morphine Inhibited the Amnesic Effect of Ethanol on Spatial Memory: Involvement of CaMKII and BDNF. Alcohol (Fayetteville, N.Y.). 2023-08-19. PMID:37597575. |
our findings suggest that sub-chronic morphine treatment reverses ethanol-induced spatial memory impairment which could be explained by modulating camkii and bdnf mrna expressions in the hippocampus and amygdala. |
2023-08-19 |
2023-09-07 |
rat |
Shubha M Basavaraju, Seema Mudhol, Muthukumar Serva Peddha, Shahid Ud Din Wani, Kamsagara L Krishna, Seema Mehdi, Nabeel Kinattinga. Nanoemulsion-based piperine to enhance bioavailability for the treatment of LPS-induced depression-like behaviour in mice. Neuroscience letters. 2023-08-17. PMID:37591360. |
within the same period, nanopiperine improved hippocampal progenitor cell proliferation and increased brain-derived neurotrophic factor (bdnf) levels in the hippocampus of mice subjected to lps-induced stress. |
2023-08-17 |
2023-09-07 |
mouse |
Shubha M Basavaraju, Seema Mudhol, Muthukumar Serva Peddha, Shahid Ud Din Wani, Kamsagara L Krishna, Seema Mehdi, Nabeel Kinattinga. Nanoemulsion-based piperine to enhance bioavailability for the treatment of LPS-induced depression-like behaviour in mice. Neuroscience letters. 2023-08-17. PMID:37591360. |
in summary, the nanopiperine showed potent neuroprotective and antidepressant activity, and stability relating to the elevated level of hippocampal bdnf level and as compared to pure piperine, the nanopiperine showed better oral bioavailability and stability. |
2023-08-17 |
2023-09-07 |
mouse |
Chiara Musillo, Letizia Giona, Michael Ristow, Kim Zarse, Karsten Siems, Alessia Di Francesco, Barbara Collacchi, Carla Raggi, Francesca Cirulli, Alessandra Berr. Rosmarinic Acid Improves Cognitive Abilities and Glucose Metabolism in Aged C57Bl/6N Mice While Disrupting Lipid Profile in Young Adults in a Sex-Dependent Fashion. Nutrients. vol 15. issue 15. 2023-08-12. PMID:37571303. |
brain-derived neurotrophic factor (bdnf) protein levels were evaluated in the hippocampus. |
2023-08-12 |
2023-08-16 |
mouse |
Hongmei Wu, Dongyu Min, Buxun Sun, Yifan Ma, Hongpeng Chen, Jing Wu, Ping Ren, Jiabi Wu, Yonggang Cao, Baoshan Zhao, Peng Wan. Effect of WiFi signal exposure in utero and early life on neurodevelopment and behaviors of rats. Environmental science and pollution research international. 2023-08-10. PMID:37561300. |
the results showed that wifi signal exposure in utero and early life (1) increased the body weight of wifi + m (wifi + male) group; (2) no change in neuro-behavioral development was observed in wifi group; (3) increased learning and memory function in wifi + m group; (4) enhanced comparative levels of bdnf and p-creb proteins in the hippocampus of wifi + m group; (5) no neuronal loss or degeneration was detected, and neuronal numbers in hippocampal ca1 were no evidently differences in each group; (6) no change in the apoptosis-related proteins (caspase-3 and bax) levels; and (7) no difference in gsh-px and sod activities in the hippocampus. |
2023-08-10 |
2023-08-16 |
rat |
Érica Vanessa Furlan Rosa, Alice Rosa DA Silveira, Marcel Henrique Marcondes Sari, Tuane Bazanella Sampaio, Jamila Trindade Dos Santos, Sabrina Grendene Müller, Michele Rechia Fighera, Luiz Fernando Freire Royes, Cristina Wayne Nogueira, Mauro Schneider Oliveira, Ana Flávia Furia. BETA-CARYOPHYLLENE MITIGATES THE COGNITIVE IMPAIRMENT CAUSED BY REPEATED EXPOSURE TO ASPARTAME IN RATS: PUTATIVE ROLE OF BDNF - TrKB SIGNALING PATHWAY AND ACETYLCHOLINESTERASE ACTIVITY. Behavioural brain research. 2023-08-09. PMID:37558167. |
molecular insights revealed augmented bdnf and trkb levels in the hippocampus of rats treated with bcp, indicating greater activation of this pathway. |
2023-08-09 |
2023-08-16 |
rat |
Marta Lorena Speck da Silva, Ana Luiza Azevedo Gomes, Camila Schafer Rojas, Julia Willig, Ana Paula Herrmann, Diogo André Pilger, Stela Maris Kuze Rate. Environmental enrichment affects behavioral and pharmacological response to antidepressants in CF1 mice. Neuroscience letters. 2023-08-07. PMID:37549865. |
bdnf gene expression in the hippocampus was determined through qpcr. |
2023-08-07 |
2023-08-14 |
mouse |
Marta Lorena Speck da Silva, Ana Luiza Azevedo Gomes, Camila Schafer Rojas, Julia Willig, Ana Paula Herrmann, Diogo André Pilger, Stela Maris Kuze Rate. Environmental enrichment affects behavioral and pharmacological response to antidepressants in CF1 mice. Neuroscience letters. 2023-08-07. PMID:37549865. |
none of the ee protocols affected bdnf hippocampal expression. |
2023-08-07 |
2023-08-14 |
mouse |
Mandana Shekarchian, Maghsoud Peeri, Mohammad Ali Azarbayjan. Physical activity in a swimming pool attenuates memory impairment by reducing glutamate and inflammatory cytokines and increasing BDNF in the brain of mice with type 2 diabetes. Brain research bulletin. 2023-08-05. PMID:37543294. |
we also measured inflammatory cytokines (interleukin (il)-6, il-1β, and tumor-necrosis-factor (tnf)-α), an anti-inflammatory cytokine (il-10), and brain-derived-neurotrophic-factor (bdnf), and glutamate levels in the hippocampus or prefrontal cortex of mice. |
2023-08-05 |
2023-08-14 |
mouse |
Mandana Shekarchian, Maghsoud Peeri, Mohammad Ali Azarbayjan. Physical activity in a swimming pool attenuates memory impairment by reducing glutamate and inflammatory cytokines and increasing BDNF in the brain of mice with type 2 diabetes. Brain research bulletin. 2023-08-05. PMID:37543294. |
the findings showed that diabetes increased body weight, glucose, and insulin resistance, impaired working, spatial and recognition memory, increased levels of il-6, il-1β, tnf-α, and glutamate levels, and decreased bdnf in the hippocampus of diabetic mice. |
2023-08-05 |
2023-08-14 |
mouse |
Mandana Shekarchian, Maghsoud Peeri, Mohammad Ali Azarbayjan. Physical activity in a swimming pool attenuates memory impairment by reducing glutamate and inflammatory cytokines and increasing BDNF in the brain of mice with type 2 diabetes. Brain research bulletin. 2023-08-05. PMID:37543294. |
while higher physical activity was associated with reduced body weight, glucose, and insulin resistance, attenuated memory impairment, il-6, il-1β, tnf-α, and glutamate, and increased bdnf levels in the hippocampus and prefrontal cortex of diabetic mice. |
2023-08-05 |
2023-08-14 |
mouse |
Lv-Ping Zhuang, Wei-Jie Gao, Liu-Lv Fang, Gui-Rong Zeng, Qin-Yong Ye, Xiao-Man Dai, Jing Zhang, Xiao-Chun Che. HnRNPK is involved in stress-induced depression-like behavior via ERK-BDNF pathway in mice. Neurochemistry international. 2023-08-05. PMID:37543308. |
further in vivo and in vitro analyses revealed that the changes in the expressions of bdnf and psd95 and in the phosphorylation of erk (thr202/tyr204) paralleled the variation of hnrnpk levels in the ventral hippocampal neurons in mice with depression-like behaviors. |
2023-08-05 |
2023-08-14 |
mouse |
Sophia Esalatmanesh, Ladan Kashani, Shahin Akhondzade. Effects of Antidepressant Medication on Brain-derived Neurotrophic Factor Concentration and Neuroplasticity in Depression: A Review of Preclinical and Clinical Studies. Avicenna journal of medical biotechnology. vol 15. issue 3. 2023-08-04. PMID:37538241. |
bdnf is the main regulatory protein that affects neuronal plasticity in the hippocampus. |
2023-08-04 |
2023-08-14 |
Not clear |
Elena A Filimonova, Anton A Pashkov, Galina I Moysak, Anastasia Y Tropynina, Svetlana Y Zhanaeva, Anna A Shvaikovskaya, Anna A Akopyan, Konstantin V Danilenko, Lyubomir I Aftanas, Maria A Tikhonova, Jamil A Rzae. Brain but not serum BDNF levels are associated with structural alterations in the hippocampal regions in patients with drug-resistant mesial temporal lobe epilepsy. Frontiers in neuroscience. vol 17. 2023-08-04. PMID:37539386. |
brain but not serum bdnf levels are associated with structural alterations in the hippocampal regions in patients with drug-resistant mesial temporal lobe epilepsy. |
2023-08-04 |
2023-08-14 |
human |
Elena A Filimonova, Anton A Pashkov, Galina I Moysak, Anastasia Y Tropynina, Svetlana Y Zhanaeva, Anna A Shvaikovskaya, Anna A Akopyan, Konstantin V Danilenko, Lyubomir I Aftanas, Maria A Tikhonova, Jamil A Rzae. Brain but not serum BDNF levels are associated with structural alterations in the hippocampal regions in patients with drug-resistant mesial temporal lobe epilepsy. Frontiers in neuroscience. vol 17. 2023-08-04. PMID:37539386. |
to narrow this gap, in this study, we aimed to estimate the relationship between hippocampal and serum levels of brain-derived neurotrophic factor (bdnf), one of the main and most widely studied neurotrophins, and hippocampal subfield volumes in patients with drug-resistant mesial temporal epilepsy undergoing neurosurgical treatment. |
2023-08-04 |
2023-08-14 |
human |