| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lucia Caffino, Francesca Mottarlini, Alessandro Piva, Beatrice Rizzi, Fabio Fumagalli, Cristiano Chiamuler. Temporal dynamics of BDNF signaling recruitment in the rat prefrontal cortex and hippocampus following a single infusion of a translational dose of ketamine. Neuropharmacology. 2023-10-20. PMID:37858883. |
we focused on the first 24 h after infusion to finely dissect potential differences in the contribution of bdnf signaling pathway in prefrontal cortex and hippocampus, two brain regions involved in the antidepressant effects of ketamine. |
2023-10-20 |
2023-11-08 |
rat |
| Lucia Caffino, Francesca Mottarlini, Alessandro Piva, Beatrice Rizzi, Fabio Fumagalli, Cristiano Chiamuler. Temporal dynamics of BDNF signaling recruitment in the rat prefrontal cortex and hippocampus following a single infusion of a translational dose of ketamine. Neuropharmacology. 2023-10-20. PMID:37858883. |
we have captured previously unknown dynamics of the early effects of ketamine showing rapid activation/deactivation of bdnf and its downstream signaling in prefrontal cortex and hippocampus, following a precise temporal profile. |
2023-10-20 |
2023-11-08 |
rat |
| Arianna Casini, Giorgio Vivacqua, Rosa Vaccaro, Anastasia Renzi, Stefano Leone, Luigi Pannarale, Antonio Franchitto, Paolo Onori, Romina Mancinelli, Eugenio Gaudi. Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium. European journal of histochemistry : EJH. vol 67. issue 4. 2023-10-20. PMID:37859350. |
cart increases the survival of hippocampal neurons by upregulating brain-derived neurotrophic factor (bdnf), whose expression has been correlated to the proliferation rate of cholangiocytes. |
2023-10-20 |
2023-11-08 |
rat |
| Lingyu Qin, Junming Wang, Xiaohui Wu, Lingling Song, Yueyue Zhang, Mingzhu Gong, Yanmei Wang, Bingyin L. Antidepressant effects of 70% ethanolic extract of Lonicerae japonicae flos and it contained chlorogenic acid via upregulation of BDNF-TrkB pathway in the hippocampus of mice. Brain research bulletin. 2023-10-20. PMID:37863440. |
moreover, ljf-70% ethanolic extract and cga improved cums induced depressive behavior, upregulated protein expression levels of bdnf and p-trkb in the hippocampus, restored the damage of hippocampal neurons, and protect liver from damage. |
2023-10-20 |
2023-11-08 |
mouse |
| Laryssa Alves-Borba, Verónica Espinosa-Fernández, Ania Canseco-Rodríguez, Ana María Sánchez-Pére. ABA Supplementation Rescues IRS2 and BDNF mRNA Levels in a Triple-Transgenic Mice Model of Alzheimer's Disease. Journal of Alzheimer's disease reports. vol 7. issue 1. 2023-10-18. PMID:37849638. |
here, we evaluated the effect of early and late-start abscisic acid (aba) intervention on hippocampal bdnf, tumor necrosis factor α (tnfα), and insulin receptors substrates (irs) 1/2 mrna levels in a triple-transgenic mice model of ad. |
2023-10-18 |
2023-11-08 |
mouse |
| Chidinma P Anyachor, Chinna N Orish, Anthonet N Ezejiofor, Ana Cirovic, Aleksandar Cirovic, Kenneth M Ezealisiji, Orish E Orisakw. Nickel and aluminium mixture elicit memory impairment by activation of oxidative stress, COX-2, and diminution of AChE, BDNF and NGF levels in cerebral cortex and hippocampus of male albino rats. Current research in toxicology. vol 5. 2023-10-16. PMID:37841055. |
nickel and aluminium mixture elicit memory impairment by activation of oxidative stress, cox-2, and diminution of ache, bdnf and ngf levels in cerebral cortex and hippocampus of male albino rats. |
2023-10-16 |
2023-11-08 |
rat |
| Helia Aghamiri, Majid Jafari-Sabet, Mahmood Hoorman. Ameliorative Effect of Cannabidiol on Topiramate-Induced Memory Loss: The Role of Hippocampal and Prefrontal Cortical NMDA Receptors and CREB/BDNF Signaling Pathways in Rats. Neurochemical research. 2023-10-09. PMID:37814133. |
western blot analysis was used to evaluate variations in brain-derived neurotrophic factor (bdnf) and phosphorylated cyclic amp response element-binding protein (pcreb)/creb ratio in the prefrontal cortex (pfc) and hippocampus (hpc). |
2023-10-09 |
2023-10-15 |
rat |
| William Almaguer-Melian, Daymara Mercerón-Martinez, Esteban Alberti-Amador, Laura Alacán-Ricardo, Javier Curi de Bardet, Norma Orama-Rojo, Arturo Ernesto Vergara-Piña, Idalia Herrera Estrada, Jorge A Bergad. Learning induces EPO/EPOr expression in memory relevant brain areas, whereas exogenously applied EPO promotes remote memory consolidation. Synapse (New York, N.Y.). 2023-10-05. PMID:37794768. |
data show that learning induces epo/epor expression increase linked to memory extent, exogenous epo prolongs memory up to 21 days; and prefrontal cortex bdnf expression at 24 h and in the hippocampus at 21 days, whereas arc expression increases at 21 days in the hippocampus and prefrontal cortex. |
2023-10-05 |
2023-10-07 |
Not clear |
| Zi-Ai Zhu, Yi-Yan Li, Juan Xu, Hui Xue, Xue Feng, Yong-Chuan Zhu, Zhi-Qi Xion. CDKL5 deficiency in adult glutamatergic neurons alters synaptic activity and causes spontaneous seizures via TrkB signaling. Cell reports. vol 42. issue 10. 2023-10-01. PMID:37777961. |
we observe increased expression of brain-derived neurotrophic factor (bdnf) and enhanced activation of its receptor trkb in the hippocampus of cdkl5-deficient mice prior to the onset of behavioral seizures. |
2023-10-01 |
2023-10-07 |
mouse |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
systemic administration of nicotine at a dose of 0.5 mg/kg induced an anxiogenic-like response associated with decreased bdnf levels in the hippocampus and the pfc. |
2023-10-01 |
2023-10-07 |
rat |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
intra-md microinjection of apomorphine (0.1-0.3 μg/rat) induced an anxiogenic-like response, while apomorphine inhibited nicotine-induced anxiogenic-like behaviors associated with increased hippocampal and pfc bdnf expression levels. |
2023-10-01 |
2023-10-07 |
rat |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
interestingly, the blockade of the vh or the pfc nmda receptors via the microinjection of d-ap5 (0.3-0.5 μg/rat) into the targeted sites reversed the inhibitory effect of apomorphine (0.5 μg/rat, intra-md) on the nicotine response and led to the decrease of bdnf levels in the hippocampus and the pfc. |
2023-10-01 |
2023-10-07 |
rat |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
these findings suggest that the functional interaction between the md dopaminergic d1/d2-like and the vh/pfc glutamatergic nmda receptors may be partially involved in the anxiogenic-like effects of nicotine, likely via the alteration of bdnf levels in the hippocampus and the pfc. |
2023-10-01 |
2023-10-07 |
rat |
| Marah Alsalloum, Tatiana Ilchibaeva, Anton Tsybko, Dmitry Eremin, Vladimir Naumenk. A Truncated Receptor TrkB Isoform (TrkB.T1) in Mechanisms of Genetically Determined Depressive-like Behavior of Mice. Biomedicines. vol 11. issue 9. 2023-09-28. PMID:37761014. |
trkb.t1 overexpression lowered bdnf protein concentration in the hippocampus. |
2023-09-28 |
2023-10-07 |
mouse |
| Omar Gammoh, Esam Y Qnais, Rabaa Y Athamneh, Bilal Al-Jaidi, Deniz Al-Tawalbeh, Sara Altaber, Abdelrahim Alqudah, Alaa A A Aljabali, Murtaza M Tambuwal. Unraveling the Potential of Isorhamnetin as an Adjuvant in Depression Treatment with Escitalopram. Current issues in molecular biology. vol 45. issue 9. 2023-09-27. PMID:37754268. |
additionally, enzyme-linked immunosorbent assays were utilized to measure nrf2, bdnf, ho-1, no, and il-6 levels in the prefrontal cortex and hippocampus. |
2023-09-27 |
2023-10-07 |
mouse |
| Stanislava Bukatova, Alexandra Reichova, Zuzana Bacova, Jan Bako. Neonatal oxytocin treatment alters levels of precursor and mature BDNF forms and modifies the expression of neuronal markers in the male rat hippocampus. Neuropeptides. vol 102. 2023-09-23. PMID:37741113. |
neonatal oxytocin treatment alters levels of precursor and mature bdnf forms and modifies the expression of neuronal markers in the male rat hippocampus. |
2023-09-23 |
2023-10-07 |
rat |
| Stanislava Bukatova, Alexandra Reichova, Zuzana Bacova, Jan Bako. Neonatal oxytocin treatment alters levels of precursor and mature BDNF forms and modifies the expression of neuronal markers in the male rat hippocampus. Neuropeptides. vol 102. 2023-09-23. PMID:37741113. |
therefore, the aim of the present study was to evaluate the early developmental effect of oxytocin administration (p2 and p3 days, two doses, 5 μg/pup, s.c.) on the expression of 1) brain-derived neurotrophic factor (bdnf) isoforms and 2) gabaergic and glutamatergic markers in the male rat hippocampus. |
2023-09-23 |
2023-10-07 |
rat |
| Jie Yuan, Jing Gao, Kai-Qi Su, Xiao-Dong Fen. [Electroacupuncture improves learning and memory impairment and enhances hippocampal synaptic plasticity through BDNF/TRKB/CREB signaling pathway in cerebral ischemia-reperfusion injury rats]. Zhen ci yan jiu = Acupuncture research. vol 48. issue 9. 2023-09-20. PMID:37730254. |
to observe the effect of electroacupuncture on brain-derived neurotrophin factor (bdnf) / tyrosine kinase receptor b (trkb) / cyclic adenosine monophosphate response element binding protein (creb) pathway, synaptic plasticity marker protein and synaptic ultrastructure in the hippocampus of rats with learning and memory impairment induced by cerebral ischemia reperfusion (ir), so as to explore its mechanisms underlying improvement of cognitive impairment after stroke. |
2023-09-20 |
2023-10-07 |
rat |
| Eleni H Moschonas, Tyler S Ranellone, Vincent J Vozzella, Piper L Rennerfeldt, Corina O Bondi, Ellen M Annas, Rachel A Bittner, Dana M Tamura, Rithika I Reddy, Rithik R Eleti, Jeffrey P Cheng, Jessica M Jarvis, Ericka L Fink, Anthony E Klin. Efficacy of a music-based intervention in a preclinical model of traumatic brain injury: An initial foray into a novel and non-pharmacological rehabilitative therapy. Experimental neurology. 2023-09-19. PMID:37726048. |
music also reduced cortical lesion volume and activated microglia but increased resting microglia and hippocampal bdnf expression. |
2023-09-19 |
2023-10-07 |
rat |
| S Mohammad Ahmadi-Soleimani, Ghulam Yahya Amiry, Elnaz Khordad, Maha Masoudi, Farimah Behesht. Omega-3 fatty acids prevent nicotine withdrawal-induced impairment of learning and memory via affecting oxidative status, inflammatory response, cholinergic activity, BDNF and amyloid-B in rat hippocampal tissues. Life sciences. 2023-09-18. PMID:37722588. |
omega-3 fatty acids prevent nicotine withdrawal-induced impairment of learning and memory via affecting oxidative status, inflammatory response, cholinergic activity, bdnf and amyloid-b in rat hippocampal tissues. |
2023-09-18 |
2023-10-07 |
rat |