| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
systemic administration of nicotine at a dose of 0.5 mg/kg induced an anxiogenic-like response associated with decreased bdnf levels in the hippocampus and the pfc. |
2023-10-01 |
2023-10-07 |
rat |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
intra-md microinjection of apomorphine (0.1-0.3 μg/rat) induced an anxiogenic-like response, while apomorphine inhibited nicotine-induced anxiogenic-like behaviors associated with increased hippocampal and pfc bdnf expression levels. |
2023-10-01 |
2023-10-07 |
rat |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
interestingly, the blockade of the vh or the pfc nmda receptors via the microinjection of d-ap5 (0.3-0.5 μg/rat) into the targeted sites reversed the inhibitory effect of apomorphine (0.5 μg/rat, intra-md) on the nicotine response and led to the decrease of bdnf levels in the hippocampus and the pfc. |
2023-10-01 |
2023-10-07 |
rat |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
these findings suggest that the functional interaction between the md dopaminergic d1/d2-like and the vh/pfc glutamatergic nmda receptors may be partially involved in the anxiogenic-like effects of nicotine, likely via the alteration of bdnf levels in the hippocampus and the pfc. |
2023-10-01 |
2023-10-07 |
rat |
| Marah Alsalloum, Tatiana Ilchibaeva, Anton Tsybko, Dmitry Eremin, Vladimir Naumenk. A Truncated Receptor TrkB Isoform (TrkB.T1) in Mechanisms of Genetically Determined Depressive-like Behavior of Mice. Biomedicines. vol 11. issue 9. 2023-09-28. PMID:37761014. |
trkb.t1 overexpression lowered bdnf protein concentration in the hippocampus. |
2023-09-28 |
2023-10-07 |
mouse |
| Omar Gammoh, Esam Y Qnais, Rabaa Y Athamneh, Bilal Al-Jaidi, Deniz Al-Tawalbeh, Sara Altaber, Abdelrahim Alqudah, Alaa A A Aljabali, Murtaza M Tambuwal. Unraveling the Potential of Isorhamnetin as an Adjuvant in Depression Treatment with Escitalopram. Current issues in molecular biology. vol 45. issue 9. 2023-09-27. PMID:37754268. |
additionally, enzyme-linked immunosorbent assays were utilized to measure nrf2, bdnf, ho-1, no, and il-6 levels in the prefrontal cortex and hippocampus. |
2023-09-27 |
2023-10-07 |
mouse |
| Stanislava Bukatova, Alexandra Reichova, Zuzana Bacova, Jan Bako. Neonatal oxytocin treatment alters levels of precursor and mature BDNF forms and modifies the expression of neuronal markers in the male rat hippocampus. Neuropeptides. vol 102. 2023-09-23. PMID:37741113. |
neonatal oxytocin treatment alters levels of precursor and mature bdnf forms and modifies the expression of neuronal markers in the male rat hippocampus. |
2023-09-23 |
2023-10-07 |
rat |
| Stanislava Bukatova, Alexandra Reichova, Zuzana Bacova, Jan Bako. Neonatal oxytocin treatment alters levels of precursor and mature BDNF forms and modifies the expression of neuronal markers in the male rat hippocampus. Neuropeptides. vol 102. 2023-09-23. PMID:37741113. |
therefore, the aim of the present study was to evaluate the early developmental effect of oxytocin administration (p2 and p3 days, two doses, 5 μg/pup, s.c.) on the expression of 1) brain-derived neurotrophic factor (bdnf) isoforms and 2) gabaergic and glutamatergic markers in the male rat hippocampus. |
2023-09-23 |
2023-10-07 |
rat |
| Jie Yuan, Jing Gao, Kai-Qi Su, Xiao-Dong Fen. [Electroacupuncture improves learning and memory impairment and enhances hippocampal synaptic plasticity through BDNF/TRKB/CREB signaling pathway in cerebral ischemia-reperfusion injury rats]. Zhen ci yan jiu = Acupuncture research. vol 48. issue 9. 2023-09-20. PMID:37730254. |
to observe the effect of electroacupuncture on brain-derived neurotrophin factor (bdnf) / tyrosine kinase receptor b (trkb) / cyclic adenosine monophosphate response element binding protein (creb) pathway, synaptic plasticity marker protein and synaptic ultrastructure in the hippocampus of rats with learning and memory impairment induced by cerebral ischemia reperfusion (ir), so as to explore its mechanisms underlying improvement of cognitive impairment after stroke. |
2023-09-20 |
2023-10-07 |
rat |
| Eleni H Moschonas, Tyler S Ranellone, Vincent J Vozzella, Piper L Rennerfeldt, Corina O Bondi, Ellen M Annas, Rachel A Bittner, Dana M Tamura, Rithika I Reddy, Rithik R Eleti, Jeffrey P Cheng, Jessica M Jarvis, Ericka L Fink, Anthony E Klin. Efficacy of a music-based intervention in a preclinical model of traumatic brain injury: An initial foray into a novel and non-pharmacological rehabilitative therapy. Experimental neurology. 2023-09-19. PMID:37726048. |
music also reduced cortical lesion volume and activated microglia but increased resting microglia and hippocampal bdnf expression. |
2023-09-19 |
2023-10-07 |
rat |
| S Mohammad Ahmadi-Soleimani, Ghulam Yahya Amiry, Elnaz Khordad, Maha Masoudi, Farimah Behesht. Omega-3 fatty acids prevent nicotine withdrawal-induced impairment of learning and memory via affecting oxidative status, inflammatory response, cholinergic activity, BDNF and amyloid-B in rat hippocampal tissues. Life sciences. 2023-09-18. PMID:37722588. |
omega-3 fatty acids prevent nicotine withdrawal-induced impairment of learning and memory via affecting oxidative status, inflammatory response, cholinergic activity, bdnf and amyloid-b in rat hippocampal tissues. |
2023-09-18 |
2023-10-07 |
rat |
| Sareh Kazmi, Fereshteh Farajdokht, Reza Meynaghizadeh-Zargar, Saeed Sadigh-Eteghad, Amir Pasokh, Mohammad Farzipour, Narmin Farazi, Michael R Hamblin, Javad Mahmoud. Transcranial photobiomodulation mitigates learning and memory impairments induced by hindlimb unloading in a mouse model of microgravity exposure by suppression of oxidative stress and neuroinflammation signaling pathways. Brain research. 2023-09-17. PMID:37717889. |
spatial learning and memory were assessed in the lashley iii maze and hippocampus tissue samples were collected to assess oxidative stress markers and protein expression of brain-derived neurotrophic factor (bdnf), nuclear factor erythroid 2-related factor 2 (nrf2), sirtuin 1 (sirt1), and nuclear factor kappa-light-chain-enhancer of activated b cells (nf-κb). |
2023-09-17 |
2023-10-07 |
mouse |
| Sareh Kazmi, Fereshteh Farajdokht, Reza Meynaghizadeh-Zargar, Saeed Sadigh-Eteghad, Amir Pasokh, Mohammad Farzipour, Narmin Farazi, Michael R Hamblin, Javad Mahmoud. Transcranial photobiomodulation mitigates learning and memory impairments induced by hindlimb unloading in a mouse model of microgravity exposure by suppression of oxidative stress and neuroinflammation signaling pathways. Brain research. 2023-09-17. PMID:37717889. |
our findings suggested that the protective effect of pbm against hu-induced cognitive impairment involved the activation of the sirt1/nrf2 signaling pathway, up-regulation of bdnf, and reduction of neuroinflammation and oxidative stress in the hippocampus. |
2023-09-17 |
2023-10-07 |
mouse |
| Radwa S Raafat, Mohamed Z Habib, Amany A AbdElfattah, Nouran K Olama, Sahar M Abdelraouf, Nevien Hendawy, Khaled A Kamal, Salwa A Nawishy, Sawsan Aboul-Fotou. Amisulpride attenuates 5-fluorouracil-induced cognitive deficits via modulating hippocampal Wnt/GSK-3β/β-catenin signaling in Wistar rats. International immunopharmacology. vol 124. issue Pt A. 2023-09-16. PMID:37716161. |
moreover, 5-fu induced a decrease in the activity of the wnt/gsk-3β/β-catenin pathway with a decrease in brain-derived neurotrophic factor (bdnf) level in the hippocampus. |
2023-09-16 |
2023-10-07 |
human |
| Ofelia Limón-Morales, Kenia Morales-Quintero, Marcela Arteaga-Silva, Tania Molina-Jiménez, Marco Cerbón, Herlinda Bonilla-Jaim. Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats. Behavioural brain research. 2023-09-15. PMID:37714467. |
this, study, then, was designed to analyze the long-term effects of early postnatal exposure to cmi on the expression of 5-ht1a, 5-ht2a, and 5-ht3 receptors, as well as bdnf and gr in the following brain regions: pfc, amygdala, hippocampus, and hypothalamus, which could be related to alterations in memory and learning, as evaluated using the novel object recognition (nor) and morris water maze (mwm). |
2023-09-15 |
2023-10-07 |
rat |
| Ofelia Limón-Morales, Kenia Morales-Quintero, Marcela Arteaga-Silva, Tania Molina-Jiménez, Marco Cerbón, Herlinda Bonilla-Jaim. Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats. Behavioural brain research. 2023-09-15. PMID:37714467. |
expression of the 5-ht1a receptor increased in the hippocampus, amygdala, and hypothalamus, but decreased in the pfc, while the 5-ht2a and bdnf receptors decreased their expression in the pfc, amygdala, and hippocampus. |
2023-09-15 |
2023-10-07 |
rat |
| M Hernandez, S Ghislin, R Lalonde, C Straziell. Corticosterone effects on postnatal cerebellar development in mice. Neurochemistry international. 2023-09-13. PMID:37704081. |
the cort treatment altered the morphology of the hippocampus and down-regulated gene transcription for corticotropin-releasing hormone (crh) and its type-1 receptor (crhr1), glucocorticoid receptor (nr3c1), and brain-derived neurotrophic factor bdnf and its receptor ntrk2 (neurotrophic receptor tyrosine kinase 2). |
2023-09-13 |
2023-10-07 |
mouse |
| Hyejin Kwon, Eun-Hwa Lee, So-Young Park, Jin-Young Park, Jin-Hwan Hong, Eun-Kyung Kim, Tae-Seop Shin, Yoon-Keun Kim, Pyung-Lim Ha. Lactobacillus-derived extracellular vesicles counteract Aβ42-induced abnormal transcriptional changes through the upregulation of MeCP2 and Sirt1 and improve Aβ pathology in Tg-APP/PS1 mice. Experimental & molecular medicine. 2023-09-13. PMID:37704750. |
lpc-ev treatment restores the downregulated expression of bdnf, nt4/5, trkb, mmp-2, mmp-9, and nep; induces the upregulation of mecp2 and sirt1 in the hippocampus; alleviates aβ accumulation and neuroinflammatory responses in the brain; and mitigates cognitive decline in tg-app/ps1 mice. |
2023-09-13 |
2023-10-07 |
mouse |
| Cristina Lao-Peregrin, Guoqing Xiang, Jihye Kim, Ipsit Srivastava, Alexandra B Fall, Danielle M Gerhard, Piia Kohtala, Daegeon Kim, Minseok Song, Mikel Garcia-Marcos, Joshua Levitz, Francis S Le. Synaptic plasticity via receptor tyrosine kinase/G protein-coupled receptor crosstalk. bioRxiv : the preprint server for biology. 2023-09-11. PMID:37693535. |
we find that the receptor tyrosine kinase (rtk), trkb, and the g protein-coupled receptor (gpcr), metabotropic glutamate receptor 5 (mglur5), together mediate a novel form of hippocampal synaptic plasticity in response to brain-derived neurotrophic factor (bdnf). |
2023-09-11 |
2023-10-07 |
Not clear |
| Jian Huang, Yongji Wu, Xuejun Chai, Shuai Wang, Yongkang Zhao, Yan Hou, Yue Ma, Shulin Chen, Shanting Zhao, Xiaoyan Zh. β-Hydroxybutyric acid improves cognitive function in a model of heat stress by promoting adult hippocampal neurogenesis. Stress biology. vol 2. issue 1. 2023-09-07. PMID:37676574. |
moreover, bhba inhibited the expression of cleaved caspase-3 by suppressing endoplasmic reticulum (er) stress, and increased the expression of brain-derived neurotrophic factor (bdnf) in the heat stress-treated hippocampus by activating the protein kinase b (akt)/camp response element binding protein (creb) and methyl-cpg binding protein 2 (mecp2) pathways. |
2023-09-07 |
2023-10-07 |
mouse |