| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Erliang Kong, Xuqiang Geng, Feixiang Wu, Wei Yue, Yuming Sun, Xudong Fen. Microglial exosome miR-124-3p in hippocampus alleviates cognitive impairment induced by postoperative pain in elderly mice. Journal of cellular and molecular medicine. 2023-12-23. PMID:38140846. |
the cognitive impairment, axon demyelination, decreased bdnf, ng and increased vilip-1 expressions in hippocampus were all alleviated by exogenous exosome mir-124-3p. |
2023-12-23 |
2023-12-25 |
mouse |
| Xiao-Qin Zhu, Dong Ga. Naringenin alleviates cognitive dysfunction in rats with cerebral ischemia/reperfusion injury through up-regulating hippocampal BDNF-TrkB signaling: involving suppression in neuroinflammation and oxidative stress. Neuroreport. 2023-12-23. PMID:38141009. |
moreover, nar inhibited oxidative stress (reduced levels of malondialdehyde and 4-hydroxynonenal, increased activities of superoxide dismutase and glutathione peroxidase) and inflammatory cytokines (reduced levels of tumor necrosis factor-α, interleukin-1β and interleukin-6), up-regulated the expressions of bdnf and p-trkb in hippocampus of mcao-induced ci/r rats. |
2023-12-23 |
2023-12-25 |
rat |
| b' Alba Toll, Laura Blanco-Hinojo, Daniel Berge, Ana Manzano, Khadija El Abidi, V\\xc3\\xadctor Perez-Sol\\xc3\\xa0, Anna Man\\xc3\\xa. Relationship between thyroid-stimulating hormone, BDNF levels, and hippocampal volume in antipsychotic-na\\xc3\\xafve first-episode psychosis patients. Frontiers in psychiatry. vol 14. 2023-12-22. PMID:38130289.' |
it has been hypothesized that thyroid hormones could cause morphological modifications in the hippocampal structure through the upregulation of brain-derived neurotrophic factor (bdnf). |
2023-12-22 |
2023-12-24 |
Not clear |
| b' Alba Toll, Laura Blanco-Hinojo, Daniel Berge, Ana Manzano, Khadija El Abidi, V\\xc3\\xadctor Perez-Sol\\xc3\\xa0, Anna Man\\xc3\\xa. Relationship between thyroid-stimulating hormone, BDNF levels, and hippocampal volume in antipsychotic-na\\xc3\\xafve first-episode psychosis patients. Frontiers in psychiatry. vol 14. 2023-12-22. PMID:38130289.' |
in this study, we primarily aimed to determine the relationship between thyroid-stimulating hormone (tsh) levels, peripheral bdnf levels, and hippocampal volume in antipsychotic-naïve fep patients. |
2023-12-22 |
2023-12-24 |
Not clear |
| b' Alba Toll, Laura Blanco-Hinojo, Daniel Berge, Ana Manzano, Khadija El Abidi, V\\xc3\\xadctor Perez-Sol\\xc3\\xa0, Anna Man\\xc3\\xa. Relationship between thyroid-stimulating hormone, BDNF levels, and hippocampal volume in antipsychotic-na\\xc3\\xafve first-episode psychosis patients. Frontiers in psychiatry. vol 14. 2023-12-22. PMID:38130289.' |
relationship between thyroid-stimulating hormone, bdnf levels, and hippocampal volume in antipsychotic-naïve first-episode psychosis patients. |
2023-12-22 |
2023-12-24 |
Not clear |
| Xiaoyang Ma, Jeong-Woo Shin, Jae-Hyun Cho, Seung-Won Han, Dong-Hyun Ki. IL-6 expression-suppressing Lactobacillus reuteri strains alleviate gut microbiota-induced anxiety and depression in mice. Letters in applied microbiology. 2023-12-21. PMID:38126116. |
when l1 (weakest in vitro), l3, and l6 were orally administered in mice with pcm-induced depression, l6 most potently suppressed depression-like behaviors and hippocampal tnf-α and il-6 expression and increased hippocampal serotonin, bdnf, 5ht7, gabaarα1, and gababr1b expression, followed by l3 and l1. |
2023-12-21 |
2023-12-23 |
mouse |
| Cristina Lao-Peregrin, Guoqing Xiang, Jihye Kim, Ipsit Srivastava, Alexandra B Fall, Danielle M Gerhard, Piia Kohtala, Daegeon Kim, Minseok Song, Mikel Garcia-Marcos, Joshua Levitz, Francis S Le. Synaptic plasticity via receptor tyrosine kinase/G-protein-coupled receptor crosstalk. Cell reports. vol 43. issue 1. 2023-12-20. PMID:38117654. |
we find that the receptor tyrosine kinase (rtk) trkb and the g-protein-coupled receptor (gpcr) metabotropic glutamate receptor 5 (mglur5) together mediate hippocampal synaptic plasticity in response to brain-derived neurotrophic factor (bdnf). |
2023-12-20 |
2023-12-23 |
Not clear |
| Odair José Farias de Lima, Juliana da Silva Ribeiro, Jefferson Diego Costa Vasconcelos, Marília Freire Isidro Ferraz, Caroline Emiliane de Melo Tavares da Rosa E Silva, Waleska Maria Almeida Barros, Gilberto Ramos Vieira, Mírian Celly Medeiros Miranda David, Rhowena Jane Barbosa de Mato. Environmental enrichment changes the effects of prenatal and postnatal undernutrition on memory, anxiety traits, Bdnf and TrkB expression in the hippocampus of male adult rats. Behavioural brain research. 2023-12-20. PMID:38122904. |
environmental enrichment changes the effects of prenatal and postnatal undernutrition on memory, anxiety traits, bdnf and trkb expression in the hippocampus of male adult rats. |
2023-12-20 |
2023-12-23 |
rat |
| Heaji Lee, Sun Yeou Kim, Yunsook Li. Solanum melongena extract supplementation protected skeletal muscle and brain damage by regulation of BDNF/PGC1α/irisin pathway via brain function-related myokines in high-fat diet induced obese mice. The Journal of nutritional biochemistry. vol 124. 2023-12-19. PMID:38030047. |
accordingly, sme activated hippocampal neurotrophic factors including bdnf (1.0%, 1.2%) and its associated pgc1α/irisin pathway (pgc1α :1.1%, 1.1%; irisin:1.1%, 0.9%) significantly. |
2023-12-19 |
2023-12-23 |
mouse |
| Chiara Musillo, Kerstin C Creutzberg, Barbara Collacchi, Maria Antonietta Ajmone-Cat, Roberta De Simone, Marcello Lepre, Irmgard Amrein, Marco A Riva, Alessandra Berry, Francesca Cirull. Bdnf-Nrf-2 crosstalk and emotional behavior are disrupted in a sex-dependent fashion in adolescent mice exposed to maternal stress or maternal obesity. Translational psychiatry. vol 13. issue 1. 2023-12-19. PMID:38105264. |
our findings show that these two stressors produce overlapping effects, reducing brain anti-oxidant defenses (nrf-2) and leading to sex-dependent impairments of hippocampal bdnf expression and alterations of the emotional behavior and hpa axis functionality. |
2023-12-19 |
2023-12-21 |
mouse |
| Ping Li, Yang Liu, Man-Shu Zou, Ting-Ting Wang, Hai-Peng Guo, Ting-Ting Ren, Ying He, Hua Wang, Yu-Hong Wan. [Neuroprotective effect and mechanism of Zuogui Jiangtang Jieyu Formula on diabetes mellitus complicated with depression model rats based on CX3CL1-CX3CR1 axis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 21. 2023-12-19. PMID:38114178. |
western blot was used to measure the expression levels of cx3cl1, cx3cr1, a2a adenosine receptor(a2ar), glutamate receptor 2a(nr2a), glutamate receptor 2b(nr2b), and brain-derived neurotrophic factor(bdnf) in the hippocampus. |
2023-12-19 |
2023-12-23 |
rat |
| Ping Li, Yang Liu, Man-Shu Zou, Ting-Ting Wang, Hai-Peng Guo, Ting-Ting Ren, Ying He, Hua Wang, Yu-Hong Wan. [Neuroprotective effect and mechanism of Zuogui Jiangtang Jieyu Formula on diabetes mellitus complicated with depression model rats based on CX3CL1-CX3CR1 axis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 21. 2023-12-19. PMID:38114178. |
these results suggest that zgjtjy may exert its neuroprotective effect by inhibiting the cx3cl1-cx3cr1 axis and activation of hippocampal microglia, thereby improving neuroinflammation and abnormal activation of n-methyl-d-aspartate receptor(nmdar) subunits, and ultimately enhancing the expression of synaptic-related proteins psd95, syn1, and bdnf in the hippocampus. |
2023-12-19 |
2023-12-23 |
rat |
| Kate M O'Neill, Erin D Anderson, Shoutik Mukherjee, Srinivasa Gandu, Sara A McEwan, Anton Omelchenko, Ana R Rodriguez, Wolfgang Losert, David F Meaney, Behtash Babadi, Bonnie L Firestei. Time-dependent homeostatic mechanisms underlie brain-derived neurotrophic factor action on neural circuitry. Communications biology. vol 6. issue 1. 2023-12-19. PMID:38110605. |
here we report that bdnf treatment affects rodent hippocampal network dynamics during development and recovery from glutamate-induced excitotoxicity in culture. |
2023-12-19 |
2023-12-21 |
Not clear |
| Xingyu Yang, Ziwei Yu, Li An, Xinyue Jing, Mengqian Yuan, Tiancheng Xu, Zhi Yu, Bin Xu, Mengjiang L. Electroacupuncture stimulation ameliorates cognitive impairment induced by long-term high-fat diet by regulating microglial BDNF. Brain research. vol 1825. 2023-12-17. PMID:38103878. |
collectively, our findings suggest that es inhibits inflammation, regulates microglial bdnf, and causes remodeling of hippocampal function in mice to counteract obesity-like induced cognitive impairment. |
2023-12-17 |
2023-12-21 |
mouse |
| Setare Farokhi Larijani, Gholamreza Hassanzadeh, Maryam Zahmatkesh, Forough Radfar, Maryam Farahmandfa. Intranasal insulin intake and exercise improve memory function in amyloid-β induced Alzheimer's-like disease in rats: Involvement of hippocampal BDNF-TrkB receptor. Behavioural brain research. 2023-12-17. PMID:38104636. |
the level of hippocampal brain-derived neurotrophic factor (bdnf) and tropomyosin-related kinase b (trkb) were analyzed to understand the involvement of bdnf-trkb pathway in this modulation. |
2023-12-17 |
2023-12-21 |
rat |
| Setare Farokhi Larijani, Gholamreza Hassanzadeh, Maryam Zahmatkesh, Forough Radfar, Maryam Farahmandfa. Intranasal insulin intake and exercise improve memory function in amyloid-β induced Alzheimer's-like disease in rats: Involvement of hippocampal BDNF-TrkB receptor. Behavioural brain research. 2023-12-17. PMID:38104636. |
results showed that animals received aβ had impaired working memory, increased anxiety which were accompanied by lower protein levels of bdnf and trkb in the hippocampus. |
2023-12-17 |
2023-12-21 |
rat |
| Setare Farokhi Larijani, Gholamreza Hassanzadeh, Maryam Zahmatkesh, Forough Radfar, Maryam Farahmandfa. Intranasal insulin intake and exercise improve memory function in amyloid-β induced Alzheimer's-like disease in rats: Involvement of hippocampal BDNF-TrkB receptor. Behavioural brain research. 2023-12-17. PMID:38104636. |
the exercise training and intranasal insulin improved working memory deficits, decreased anxiety, and increased bdnf, and trkb levels in the hippocampus of animals received aβ. |
2023-12-17 |
2023-12-21 |
rat |
| Sudipta Jana, Bhaskarjyoti Giri, Sagarika Das, Anirban Manna, Subhash C Mandal, Nihar Ranjan Jan. Azadiradione up-regulates the expression of parvalbumin and BDNF via Ube3a. Gene. 2023-12-15. PMID:38101713. |
treatment of azadiradione to ht22 hippocampal cell line and in adult mice induced the expression of ube3a as well as two important synaptic function and plasticity regulating proteins, parvalbumin and brain-derived neurotropic factor (bdnf). |
2023-12-15 |
2023-12-18 |
mouse |
| Handan Deng, Yongjun Yu, Qi Sha, Weiyi Sun, Lundan Liang, Feier Ren, Hua Ji, Xiangdi Shen, Xingli Fa. Construction of antibiotic-induced depression mice model and the function of intestinal microbiota. Frontiers in microbiology. vol 14. 2023-12-13. PMID:38088959. |
by using these antibiotics, the concentrations of norepinephrine (ne), 5-hydroxytryptamine (5-ht), and brain-derived neurotrophic factor (bdnf) in mice hippocampus and prefrontal cortex tissues were significantly decreased. |
2023-12-13 |
2023-12-17 |
mouse |
| Andressa Radiske, Carla Miranda de Castro, Janine I Rossato, Maria Carolina Gonzalez, Martín Cammarot. Hippocampal CaMKII inhibition induces reactivation-dependent amnesia for extinction memory and causes fear relapse. Scientific reports. vol 13. issue 1. 2023-12-08. PMID:38066022. |
hippocampal glun2b subunit-containing nmdar (glun2b-nmdar) activation during recall destabilizes fear extinction memory, which must undergo brain-derived neurotrophic factor (bdnf)-dependent reconsolidation to persist. |
2023-12-08 |
2023-12-17 |
rat |