| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ayfer Yalcin, Ezgi Turunc, Mehmet Mahsum Kaplan, Yigit Uyanikgil, Yalcin Erzurumlu, Elisabetta Gavini, Lutfiye Kani. Potential neuroprotective effects of 2-hydroxypropyl-β cyclodextrin against amyloid β (1-42)-induced neurotoxicity on the rat hippocampus. Drug and chemical toxicology. 2024-05-10. PMID:38726980. |
the gene expressions of cav-1, mglur5, pkcβ1, pkcβ2, erk1/2, creb, bdnf, and ngf in hippocampus tissue were evaluated using reverse transcription pcr after real-time pcr analysis. |
2024-05-10 |
2024-05-27 |
rat |
| Zahra Tajabadi Farahani, Salar Vaseghi, Elham Rajabbeigi, Batool Ghorbani Yekt. The effect of olanzapine on spatial memory impairment, depressive-like behavior, pain perception, and BDNF and synaptophysin expression following childhood chronic unpredictable mild stress in adult male and female rats. Behavioural brain research. vol 468. 2024-05-09. PMID:38718877. |
in this study, we investigated the effect of olanzapine on locomotor activity (using open field test), pain threshold (using hot plate), depressive-like behavior (using forced swim test), spatial learning and memory (using morris water maze), and bdnf and synaptophysin hippocampal expression (using real-time pcr) in both male and female cums rats. |
2024-05-09 |
2024-05-27 |
rat |
| Zahra Tajabadi Farahani, Salar Vaseghi, Elham Rajabbeigi, Batool Ghorbani Yekt. The effect of olanzapine on spatial memory impairment, depressive-like behavior, pain perception, and BDNF and synaptophysin expression following childhood chronic unpredictable mild stress in adult male and female rats. Behavioural brain research. vol 468. 2024-05-09. PMID:38718877. |
our data showed that olanzapine can reverse the effects of cums on behavioral functions and bdnf and synaptophysin expression levels in the hippocampus of both males and females. |
2024-05-09 |
2024-05-27 |
rat |
| Hamed Fanaei, Behrad Tabatabaei Shoorijeh, Hamid Hafezinori, Ilia Mirzaei, Abolfazl Parsi-Mou. Impact of social isolation on corticosterone release and recovery after stroke in aged rats: A behavioral and biochemical analysis. Experimental gerontology. 2024-05-09. PMID:38723916. |
in the hippocampus of co/ph group, bdnf and tac levels were significantly higher than co/si group. |
2024-05-09 |
2024-05-27 |
rat |
| Hamed Fanaei, Behrad Tabatabaei Shoorijeh, Hamid Hafezinori, Ilia Mirzaei, Abolfazl Parsi-Mou. Impact of social isolation on corticosterone release and recovery after stroke in aged rats: A behavioral and biochemical analysis. Experimental gerontology. 2024-05-09. PMID:38723916. |
bdnf and tac levels in the hippocampus, striatum and cerebral cortex of st/ph group were significantly higher and mda level was significantly lower as compared with st/si group. |
2024-05-09 |
2024-05-27 |
rat |
| Xin Shi, Xiao-Zhong Zhou, Gang Chen, Wei-Feng Luo, Chengyu Zhou, Tian-Ju He, Mandar T Naik, Qin Jiang, John Marshall, Cong Ca. Targeting the postsynaptic scaffolding protein PSD-95 enhances BDNF signaling to mitigate depression-like behaviors in mice. Science signaling. vol 17. issue 834. 2024-04-30. PMID:38687826. |
we found that peptidomimetic compounds that bind to psd-95 promoted signaling by the bdnf receptor trkb in the hippocampus and reduced depression-like behaviors in mice. |
2024-04-30 |
2024-05-03 |
mouse |
| Jiena Hong, Jiemei Chen, Chao Li, Fei Zhao, Jiantao Zhang, Yilong Shan, Hongmei We. High-frequency rTMS alleviates cognitive impairment and regulates synaptic plasticity in the hippocampus of rats with cerebral ischemia. Behavioural brain research. vol 467. 2024-04-28. PMID:38678971. |
the underlying mechanism might be modulating the synaptic plasticity and up-regulating the expression psd95, syn, and bdnf in the hippocampus. |
2024-04-28 |
2024-05-01 |
rat |
| Erratum to: Loss in PKC Epsilon Causes Downregulation of MnSOD and BDNF Expression in Neurons of Alzheimer's Disease Hippocampus. Journal of Alzheimer's disease : JAD. 2024-04-26. PMID:38669561. |
erratum to: loss in pkc epsilon causes downregulation of mnsod and bdnf expression in neurons of alzheimer's disease hippocampus. |
2024-04-26 |
2024-04-29 |
Not clear |
| Lancheng Wei, Hongjian He, Shuting Yang, Qianqian Shi, Xinhang Wang, Liyuan Huang, Jianyong Lu, Yinghui Shen, Kaikai Zhi, Junni Xiang, Chengying Chen, Jiao Mo, Zhijian Zheng, Yunfeng Zou, Xiaobo Yang, Shen Tang, Xiyi Li, Cailing L. Synergistic suppression of BDNF via epigenetic mechanism deteriorating learning and memory impairment caused by Mn and Pb co-exposure. Ecotoxicology and environmental safety. vol 277. 2024-04-24. PMID:38657452. |
our findings reveal that co-exposure to mn and pb leads to severe learning and memory impairment in mice, which correlates with the accumulation of metals in the hippocampus and synergistic suppression of bdnf. |
2024-04-24 |
2024-04-28 |
mouse |
| Maysam Fadaei-Kenarsary, Khadijeh Esmaeilpour, Mohammad Shabani, Vahid Sheiban. Maternal Substance Use and Early-Life Adversity: Inducing Drug Dependence in Offspring, Interactions, Mechanisms, and Treatments. Addiction & health. vol 16. issue 1. 2024-04-23. PMID:38651025. |
after early-life adversity, histone acetylation in the hippocampus may be linked to brain-derived neurotrophic factor (bdnf) gene epigenetics and glucocorticoid receptors (grs). |
2024-04-23 |
2024-04-26 |
Not clear |
| Scheila Iria Kraus, Jeane Bachi Ferreira, Angela Patricia França, Vinícius Alexandre Wippel, Rodrigo Bainy Leal, Raquel Oppermann, Michele Debiasi Alberton, Morgana Duarte da Silv. Pharmacological Evidence of Eugenia Brasiliensis Leaves in a Reserpine-Induced Fibromyalgia Model: Antinociceptive, Emotional, Anti-Inflammatory, and Neurotrophic Effects. Molecular neurobiology. 2024-04-19. PMID:38639862. |
finally, we observed a reduction in inflammatory cytokines in the hippocampus of animals treated with heeb, while an increase in bdnf was observed in the prefrontal cortex (pfc). |
2024-04-19 |
2024-04-21 |
mouse |
| Yuhai Xu, Xin Xin, Tianzhu Ta. Decoding the Neurotoxic Effects of Propofol: Insights into the RARα-Snhg1-Bdnf Regulatory Cascade. American journal of physiology. Cell physiology. 2024-04-15. PMID:38618701. |
the findings draw a clear link between propofol-induced neurotoxicity and the amplification of rar signaling pathways, impacting hippocampal development and apoptosis and leading to increased rarα and snhg1 and decreased bdnf. |
2024-04-15 |
2024-04-17 |
Not clear |
| Xiyong Xiang, Siyu Xia, Shan Li, Yirong Zeng, Lixuan Wang, Yan Zho. Study on the role and mechanism of Tan IIA in Alzheimer's disease based on CREB-BDNF-TrkB pathway. Neuroscience letters. 2024-04-14. PMID:38616003. |
tan iia can significantly increase the expression of creb, bdnf, trkb in the hippocampal tissue of stz-injured rats (p < 0.05). |
2024-04-14 |
2024-04-17 |
rat |
| Laura E Been, Amanda R Halliday, Sarah M Blossom, Elena M Bien, Anya G Bernhard, Grayson E Roth, Karina I Domenech Rosario, Karlie B Pollock, Petra E Abramenko, Leily M Behbehani, Gabriel J Pascal, Mary Ellen Kell. Long-Term Oral Tamoxifen Administration Decreases Brain-Derived Neurotrophic Factor in the Hippocampus of Female Long-Evans Rats. Cancers. vol 16. issue 7. 2024-04-13. PMID:38611051. |
in the brain, brain-derived neurotrophic factor (bdnf) was visualized in the hippocampus using immunohistochemistry. |
2024-04-13 |
2024-04-15 |
human |
| Laura E Been, Amanda R Halliday, Sarah M Blossom, Elena M Bien, Anya G Bernhard, Grayson E Roth, Karina I Domenech Rosario, Karlie B Pollock, Petra E Abramenko, Leily M Behbehani, Gabriel J Pascal, Mary Ellen Kell. Long-Term Oral Tamoxifen Administration Decreases Brain-Derived Neurotrophic Factor in the Hippocampus of Female Long-Evans Rats. Cancers. vol 16. issue 7. 2024-04-13. PMID:38611051. |
chronic oral tamoxifen treatment resulted in a decrease in bdnf expression across several regions of the hippocampus. |
2024-04-13 |
2024-04-15 |
human |
| Orlane Dupuis, Julien Girardie, Mélanie Van Gaever, Philippe Garnier, Jacques-Olivier Coq, Marie-Hélène Canu, Erwan Dupon. Early Movement Restriction Affects FNDC5/Irisin and BDNF Levels in Rat Muscle and Brain. International journal of molecular sciences. vol 25. issue 7. 2024-04-13. PMID:38612728. |
the bdnf level was increased in the hippocampus at p8. |
2024-04-13 |
2024-04-15 |
rat |
| Mehmet Öz, Hüseyin Erda. A TNF-α inhibitor abolishes sepsis-induced cognitive impairment in mice by modulating acetylcholine and nitric oxide homeostasis, BDNF release, and neuroinflammation. Behavioural brain research. 2024-04-10. PMID:38599251. |
blood and hippocampal tnf α and nitric oxide (no) levels, hippocampal bdnf, creb, and ach levels, and ache activity were measured by elisa. |
2024-04-10 |
2024-04-13 |
mouse |
| Retraction: "Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway". Journal of cellular physiology. 2024-04-09. PMID:38591623. |
retraction: "silencing lncrna pvt1 inhibits activation of astrocytes and increases bdnf expression in hippocampus tissues of rats with epilepsy by downregulating the wnt signaling pathway". |
2024-04-09 |
2024-04-11 |
rat |
| Retraction: "Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway". Journal of cellular physiology. 2024-04-09. PMID:38591623. |
retraction: "silencing lncrna pvt1 inhibits activation of astrocytes and increases bdnf expression in hippocampus tissues of rats with epilepsy by downregulating the wnt signaling pathway", by teng zhao, ying ding, min li, chunkui zhou, and weihong lin, j cell physiol. |
2024-04-09 |
2024-04-11 |
rat |
| Farhanah N Sallie, Leandrie Pienaar, Andrea Lubbe, Sanelisiwe Xhakaza, Srinivasa R Manne, Beatriz G de la Torre, Fernando Albericio, William Mu Daniels, Aletta Me Millen, Sooraj Baijnat. Neurobehavioral and molecular changes in a rodent model of ACTH-induced HPA axis dysfunction. Brain research. vol 1834. 2024-04-07. PMID:38580046. |
acth administration significantly increased the expression of bdnf in the hippocampus and creb in all brain regions in males (p < 0.05), but not in female rats. |
2024-04-07 |
2024-04-10 |
rat |