| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Masatake Fujimura, Takamitsu Unok. BDNF specifically expressed in hippocampal neurons is involved in methylmercury neurotoxicity resistance. Environmental toxicology. 2024-02-07. PMID:38323385. |
bdnf specifically expressed in hippocampal neurons is involved in methylmercury neurotoxicity resistance. |
2024-02-07 |
2024-02-09 |
rat |
| Ghida Hassan, Sherif A Kamar, Hagar Yousry Rady, Dina Sayed Abdelrahim, Nesma Hussein Abdel Hay Ibrahim, Noha N Lashee. A study of roflumilast treatment on functional and structural changes in hippocampus in depressed Adult male Wistar rats. PloS one. vol 19. issue 2. 2024-02-06. PMID:38315652. |
the depressed group showed significant increase in immobility time with significant decrease in swimming and struggling times, significant decrease in hippocampal pka, cerb, bdnf, dopamine, cortisone, and superoxide dismutase while hippocampal phosphodiesterase-e4, interleukin-6, and malondialdhyde levels were significantly elevated. |
2024-02-06 |
2024-02-09 |
rat |
| Rosa López-Hidalgo, Raúl Ballestín, Lorena Lorenzo, Sandra Sánchez, José Miguel Blasco-Ibáñez, Carlos Crespo, Juan Nacher, Emilio Vare. Early chronic fasudil treatment rescues hippocampal alterations in the Ts65Dn model for down syndrome. Neurochemistry international. 2024-02-03. PMID:38309665. |
we observed that treating ts65dn mice with fasudil induced an increase in neural plasticity in the hippocampus: there was an increment in the expression of psa-ncam and bdnf, in the dendritic branching and spine density of granule neurons, as well as in cell proliferation and neurogenesis in the subgranular zone. |
2024-02-03 |
2024-02-06 |
mouse |
| Navneet Dhaliwal, Jatinder Dhaliwal, Kanwaljit Chopr. 7, 8-dihydroxyflavone Ameliorates Cholinergic Dysfunction, Inflammation, Oxidative Stress, and Apoptosis in a Rat Model of Vascular Dementia. Neurochemical research. 2024-02-01. PMID:38300457. |
p-akt, p-creb, bdnf, and neurotransmitter (nt) (glu, gaba, and ach) levels were also analyzed in the hippocampus of 2-vo rats. our results show that 7,8-dhf effectively improved memory performance and cholinergic dysfunction in 2-vo model rats. |
2024-02-01 |
2024-02-03 |
rat |
| Micaela Gliozzi, Anna Rita Coppoletta, Antonio Cardamone, Vincenzo Musolino, Cristina Carresi, Saverio Nucera, Stefano Ruga, Federica Scarano, Francesca Bosco, Lorenza Guarnieri, Roberta Macrì, Rocco Mollace, Catherine Belzung, Vincenzo Mollac. The dangerous "West Coast Swing" by hyperglycaemia and chronic stress in the mouse hippocampus: role of kynurenine catabolism. Pharmacological research. 2024-02-01. PMID:38301816. |
we demonstrated that the coexistence of hyperglycaemia and chronic stress worsened hippocampal damage through alternative mechanisms, such as glut-4 and bdnf down-expression, denoting mitochondrial dysfunction and apoptosis on one hand and evoking the compromission of neurogenesis on the other. |
2024-02-01 |
2024-02-04 |
mouse |
| Clémence Leger, Aurore Quirié, Alexandre Méloux, Estelle Fontanier, Rémi Chaney, Christelle Basset, Stéphanie Lemaire, Philippe Garnier, Anne Prigent-Tessie. Impact of Exercise Intensity on Cerebral BDNF Levels: Role of FNDC5/Irisin. International journal of molecular sciences. vol 25. issue 2. 2024-01-27. PMID:38279218. |
soleus (sol) versus gastrocnemius (gas) fndc5 and hippocampal bdnf expressions were evaluated by western blotting. |
2024-01-27 |
2024-01-29 |
rat |
| Clémence Leger, Aurore Quirié, Alexandre Méloux, Estelle Fontanier, Rémi Chaney, Christelle Basset, Stéphanie Lemaire, Philippe Garnier, Anne Prigent-Tessie. Impact of Exercise Intensity on Cerebral BDNF Levels: Role of FNDC5/Irisin. International journal of molecular sciences. vol 25. issue 2. 2024-01-27. PMID:38279218. |
our findings revealed that (1) serum irisin and hippocampal bdnf levels vary with ex intensity, showing a threshold intensity at 50% of mas; (2) hippocampal bdnf levels positively correlate with serum irisin but not with hippocampal fndc5/irisin; and (3) gas, in response to ex intensity, overexpresses fndc5/irisin in type ii muscle fibers. |
2024-01-27 |
2024-01-29 |
rat |
| Clémence Leger, Aurore Quirié, Alexandre Méloux, Estelle Fontanier, Rémi Chaney, Christelle Basset, Stéphanie Lemaire, Philippe Garnier, Anne Prigent-Tessie. Impact of Exercise Intensity on Cerebral BDNF Levels: Role of FNDC5/Irisin. International journal of molecular sciences. vol 25. issue 2. 2024-01-27. PMID:38279218. |
altogether, peripheral fndc5/irisin levels likely explain ex-dependent hippocampal bdnf expression. |
2024-01-27 |
2024-01-29 |
rat |
| Ling-Sha Ju, Jiepei Zhu, Timothy Morey, Nikolaus Gravenstein, Christoph Seubert, Barry Setlow, Anatoly Martynyu. Neurobehavioral abnormalities in offspring of young adult male rats with a history of traumatic brain injury. Journal of neurotrauma. 2024-01-27. PMID:38279844. |
these abnormalities were underpinned by reduced mrna levels of hypothalamic and hippocampal mineralocorticoid receptors (nr3c2), hippocampal nr3c1, and hypothalamic brain-derived neurotrophic factor (bdnf), as well as elevated serum levels of il-1β, and biomarkers of activated hippocampal microglia and astrocytes. |
2024-01-27 |
2024-01-30 |
rat |
| Ling-Sha Ju, Jiepei Zhu, Timothy Morey, Nikolaus Gravenstein, Christoph Seubert, Barry Setlow, Anatoly Martynyu. Neurobehavioral abnormalities in offspring of young adult male rats with a history of traumatic brain injury. Journal of neurotrauma. 2024-01-27. PMID:38279844. |
f1 male offspring of tbi sires, also had reduced mrna levels of hippocampal nr3c1 and nr3c2, as well as hypothalamic and hippocampal bdnf, whereas increases in inflammatory markers were more profound in f1 females. |
2024-01-27 |
2024-01-30 |
rat |
| Changran Niu, Xinpei Yue, Juan Ji An, Robert Bass, Haifei Xu, Baoji X. Genetic Dissection of BDNF and TrkB Expression in Glial Cells. Biomolecules. vol 14. issue 1. 2024-01-23. PMID:38254691. |
moreover, there are a small number of astrocytes and oligodendrocytes that express bdnf in the hippocampus, the function of which is to be determined. |
2024-01-23 |
2024-01-25 |
mouse |
| Justyna Socha, Pawel Grochecki, Irena Smaga, Joanna Jastrzębska, Olga Wronikowska-Denysiuk, Marta Marszalek-Grabska, Tymoteusz Slowik, Robert Kotlinski, Małgorzata Filip, Gert Lubec, Jolanta H Kotlinsk. Social Interaction in Adolescent Rats with Neonatal Ethanol Exposure: Impact of Sex and CE-123, a Selective Dopamine Reuptake Inhibitor. International journal of molecular sciences. vol 25. issue 2. 2024-01-23. PMID:38256113. |
in the hippocampus of adolescent rats, ce-123 increased bdnf and decreased its signal transduction trkb receptor expression level in ethanol-exposed animals during development, suggesting an increase in neuroplasticity. |
2024-01-23 |
2024-01-25 |
rat |
| Philine Marchetta, Konrad Dapper, Morgan Hess, Dila Calis, Wibke Singer, Jakob Wertz, Stefan Fink, Steffen R Hage, Mesbah Alam, Kerstin Schwabe, Robert Lukowski, Jerome Bourien, Jean-Luc Puel, Michele H Jacob, Matthias H J Munk, Rüdiger Land, Lukas Rüttiger, Marlies Knippe. Dysfunction of specific auditory fibers impacts cortical oscillations, driving an autism phenotype despite near-normal hearing. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 38. issue 2. 2024-01-20. PMID:38243766. |
local field potentials (lfps) were recorded from auditory, visual, and prefrontal cortices and the hippocampus of bdnf |
2024-01-20 |
2024-01-22 |
Not clear |
| Anisha A DSouza, Praveen Kulkarni, Craig F Ferris, Mansoor M Amiji, Benjamin S Bleie. Mild repetitive TBI reduces brain-derived neurotrophic factor (BDNF) in the substantia nigra and hippocampus: A preclinical model for testing BDNF-targeted therapeutics. Experimental neurology. 2024-01-20. PMID:38244886. |
mild repetitive tbi reduces brain-derived neurotrophic factor (bdnf) in the substantia nigra and hippocampus: a preclinical model for testing bdnf-targeted therapeutics. |
2024-01-20 |
2024-01-23 |
rat |
| Anisha A DSouza, Praveen Kulkarni, Craig F Ferris, Mansoor M Amiji, Benjamin S Bleie. Mild repetitive TBI reduces brain-derived neurotrophic factor (BDNF) in the substantia nigra and hippocampus: A preclinical model for testing BDNF-targeted therapeutics. Experimental neurology. 2024-01-20. PMID:38244886. |
bdnf levels, as assessed by elisa, were significantly reduced in the hippocampus of both males and females as well as in the substantia nigra of males 12 days after mild tbi. |
2024-01-20 |
2024-01-23 |
rat |
| Swamynathan Sowndharya, Koilmani Emmanuvel Raja. Environmental enrichment improves social isolation-induced memory impairment: The possible role of ITSN1-Reelin-AMPA receptor signaling pathway. PloS one. vol 19. issue 1. 2024-01-19. PMID:38241230. |
in addition, si induced reduction in bdnf expressing neurons in dentate gyrus of hippocampus reversed by ee. |
2024-01-19 |
2024-01-22 |
mouse |
| Fernanda Frederico Gava, Raquel Jaconi De Carli, Solange Stork, Lucineia Gainski Danielski, Sandra Bonfante, Larissa Joaquim, Kiuanne Lino Lobo Metzker, Khiany Mathias, David Santos, Guilherme Darós, Marina Goulart, Rafael Mariano de Bitencourt, Josiane Somariva Prophiro, Cinara Ludvig Gonçalves, Jaqueline Generoso, Tatiana Barichello, Fabricia Petronilh. Cannabidiol effect on long-term brain alterations in septic rats: Involvement of PPARγ activation. Brain research. 2024-01-19. PMID:38242525. |
during this period, the survival rate was recorded, and at the end of 10 days, a memory test was performed, and the prefrontal cortex and hippocampus were removed to verify brain-derived neurotrophic factor (bdnf), cytokines (il-1β, il-6 and il-10), myeloperoxidase activity, nitrite nitrate concentration, and lipid and protein carbonylation and catalase activity. |
2024-01-19 |
2024-01-22 |
rat |
| Fernanda Frederico Gava, Raquel Jaconi De Carli, Solange Stork, Lucineia Gainski Danielski, Sandra Bonfante, Larissa Joaquim, Kiuanne Lino Lobo Metzker, Khiany Mathias, David Santos, Guilherme Darós, Marina Goulart, Rafael Mariano de Bitencourt, Josiane Somariva Prophiro, Cinara Ludvig Gonçalves, Jaqueline Generoso, Tatiana Barichello, Fabricia Petronilh. Cannabidiol effect on long-term brain alterations in septic rats: Involvement of PPARγ activation. Brain research. 2024-01-19. PMID:38242525. |
only cbd alone improved the cognitive impairment, which was accompanied by restoration of bdnf, reduced neuroinflammation, and oxidative stress, mainly in the hippocampus. |
2024-01-19 |
2024-01-22 |
rat |
| Maria A Tikhonova, Anna A Shvaikovskaya, Svetlana Y Zhanaeva, Galina I Moysak, Anna A Akopyan, Jamil A Rzaev, Konstantin V Danilenko, Lyubomir I Aftana. Concordance between the In Vivo Content of Neurospecific Proteins (BDNF, NSE, VILIP-1, S100B) in the Hippocampus and Blood in Patients with Epilepsy. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203674. |
concordance between the in vivo content of neurospecific proteins (bdnf, nse, vilip-1, s100b) in the hippocampus and blood in patients with epilepsy. |
2024-01-11 |
2024-01-13 |
human |
| Maria A Tikhonova, Anna A Shvaikovskaya, Svetlana Y Zhanaeva, Galina I Moysak, Anna A Akopyan, Jamil A Rzaev, Konstantin V Danilenko, Lyubomir I Aftana. Concordance between the In Vivo Content of Neurospecific Proteins (BDNF, NSE, VILIP-1, S100B) in the Hippocampus and Blood in Patients with Epilepsy. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203674. |
this study aimed to assess the correspondence of the expression of bdnf, nse, vilip-1, and s100b in the blood (serum and peripheral blood mononuclear cells (pbmcs)) to the in vivo hippocampal levels of subjects with drug-resistant epilepsy who underwent neurosurgery (n = 44) using multiplex solid-phase analysis, elisa, and immunohistochemical methods, as well as to analyze the correlations and associations of the blood and hippocampal levels of these proteins with clinical parameters. |
2024-01-11 |
2024-01-13 |
human |