| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kenta Deriha, Eri Hashimoto, Wataru Ukai, Francesca Marchisella, Emi Nishimura, Hanako Hashiguchi, Masaya Tayama, Takao Ishii, Marco A Riva, Chiaki Kawanish. Reduced sociability in a prenatal immune activation model: Modulation by a chronic blonanserin treatment through the amygdala-hippocampal axis. Journal of psychiatric research. vol 164. 2023-06-28. PMID:37379611. |
low dose of blonanserin and haloperidol altered gaba and glutamate-related mrna levels, the e/i ratio, and bdnf long 3'utr mrna levels in the ventral hippocampus and amygdala, but did not attenuate behavioral impairments. |
2023-06-28 |
2023-08-14 |
rat |
| Kenta Deriha, Eri Hashimoto, Wataru Ukai, Francesca Marchisella, Emi Nishimura, Hanako Hashiguchi, Masaya Tayama, Takao Ishii, Marco A Riva, Chiaki Kawanish. Reduced sociability in a prenatal immune activation model: Modulation by a chronic blonanserin treatment through the amygdala-hippocampal axis. Journal of psychiatric research. vol 164. 2023-06-28. PMID:37379611. |
these results strongly implicate changes in pv expression, pv(+) gabaergic interneuron density, and bdnf long 3'utr expression levels, particularly in the dorsal hippocampus, in the pathophysiology and treatment responses of mia-induced schizophrenia and highlight the therapeutic potential of blonanserin for developmental stress-related schizophrenia. |
2023-06-28 |
2023-08-14 |
rat |
| Xin-Yuan Wu, Xiang Jin, Xiao-Ming Sheng, Yan Fan, Wei Gua. miR-204-5p plays a critical role in the pathogenesis of depression and anti-depression action of Venlafaxine in the hippocampus of mice. Current medicinal chemistry. 2023-06-26. PMID:37357509. |
quantitative real-time reverse transcription pcr (qrt-pcr) was also conducted to test the expression levels of mir-204 and bdnf in the hippocampus of mice. |
2023-06-26 |
2023-08-14 |
mouse |
| Hua Liu, Yang Du, Lian Lin Liu, Qing Shan Liu, Hehui Mao, Yong Chen. Anti-depression-like effect of Mogroside V is related to the inhibition of inflammatory and oxidative stress pathways. European journal of pharmacology. 2023-06-26. PMID:37364672. |
pathological changes in the hippocampal dentate gyrus and cortex regions were detected by immunofluorescence and western blotting was used to measure the protein expression of bdnf, trkb, tnf-α, and akt. |
2023-06-26 |
2023-08-14 |
Not clear |
| Samira S Valvassori, Taise Possamai-Della, Jorge M Aguiar-Geraldo, Rômulo Goronci Sant'Ana, Gustavo C Dal-Pont, Bruna Pescador, Alexandra I Zugno, João Quevedo, Felipe Dal-Pizzo. Sepsis sensitizes behavioural amphetamine responses while inducing inflammatory and neurotrophic vulnerability in the cecal ligation and puncture model. The European journal of neuroscience. 2023-06-23. PMID:37350331. |
also, brain-derived neurotrophic factor (bdnf), neuronal growth factor and glial-derived neurotrophic factor levels were assessed in the hippocampus. |
2023-06-23 |
2023-08-14 |
rat |
| Sofie Lautrup, Camilla Myrup Holst, Anne Yde, Stine Asmussen, Vibeke Thinggaard, Knud Larsen, Lisbeth Schmidt Laursen, Mette Richner, Christian B Vaegter, G Aleph Prieto, Nicole Berchtold, Carl W Cotman, Tinna Stevnsne. The role of aging and brain-derived neurotrophic factor signaling in expression of base excision repair genes in the human brain. Aging cell. 2023-06-19. PMID:37334527. |
in line with this, we identify binding sites for the bdnf-activated transcription factor, cyclic-amp response element-binding protein (creb), in the promoter of most ber genes and confirm the ability of bdnf to regulate several ber genes by bdnf treatment of mouse primary hippocampal neurons. |
2023-06-19 |
2023-08-14 |
mouse |
| Ashwani Kumar, Abhilash Prabhat, Vinod Kumar, Sanjay Kumar Bhardwa. Artificial night illumination disrupts sleep, and attenuates mood and learning in diurnal animals: evidence from behavior and gene expression studies in zebra finches. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 2023-06-17. PMID:37329435. |
further, compared to controls, there was reduced mrna expression level of genes involved in the neurogenesis, neural plasticity (bdnf, dcx and egr1) and motivation (th, drd2, taar1 and htr2c; dopamine synthesis and signaling genes) in the brain (hippocampus (hp), nidopallium caudolaterale (ncl), and midbrain) of birds under dlan. |
2023-06-17 |
2023-08-14 |
Not clear |
| Abhinav Anand, Navneet Khurana, Satinder Kaur, Nemat Ali, Abdullah F AlAsmari, Mohammad Waseem, Muzaffar Iqbal, Faris M Alzahrani, Neha Sharm. The multifactorial role of vanillin in amelioration of aluminium chloride and D-galactose induced Alzheimer's disease in mice. European journal of pharmacology. 2023-06-17. PMID:37329974. |
apart from tackling oxidative stress, vanillin was found to reduce the levels of ache, beta secretase, caspase-3, enhance degradation of abeta plaques and elevate the levels of bdnf, in cortical and hippocampal regions. |
2023-06-17 |
2023-08-14 |
mouse |
| Micaela Lucarelli, Serena Camuso, Chiara Di Pietro, Francesco Bruno, Piergiorgio La Rosa, Daniela Marazziti, Maria Teresa Fiorenza, Sonia Canterin. Reduced Cerebellar BDNF Availability Affects Postnatal Differentiation and Maturation of Granule Cells in a Mouse Model of Cholesterol Dyshomeostasis. Molecular neurobiology. 2023-06-14. PMID:37314654. |
studies conducted on cortical and hippocampal neurons indicate a functional interaction between sonic hedgehog and brain-derived neurotrophic factor (bdnf) expression, leading us to hypothesize that bdnf signaling may be altered in npc1 mutant mice, contributing to the onset of cerebellar alterations present in npc1 disease before the appearance of signs of ataxia.we characterized the expression/localization patterns of the bdnf and its receptor, tropomyosin-related kinase b (trkb), in the early postnatal and young adult cerebellum of the npc1 |
2023-06-14 |
2023-08-14 |
mouse |
| Ela Mishra, Mahendra Kumar Thaku. Mdivi-1 Rescues Memory Decline in Scopolamine-Induced Amnesic Male Mice by Ameliorating Mitochondrial Dynamics and Hippocampal Plasticity. Molecular neurobiology. 2023-06-14. PMID:37314656. |
the findings imply that mdivi-1 significantly increased the expression of arc and bdnf proteins in the hippocampus of sc-induced amnesic mice, validating improved recognition and spatial memory. |
2023-06-14 |
2023-08-14 |
mouse |
| Jingyuan Ma, Feng Xiong, Zhouru Li, Guokai Dong, Xiaoming Sun, Wenjiang Yin, Hongxing Ca. The effect of chronic alcohol exposure on spatial memory and BDNF-TrkB- PLCγ1 signaling in the hippocampus of male and female mice. Heliyon. vol 9. issue 6. 2023-06-12. PMID:37303582. |
given previously known effects of brain-derived neurotrophic factor (bdnf) in regulating synaptic plasticity and learning and memory, we investigated the effect of chronic alcohol consumption on spatial memory impairment in both sexes and changes in bdnf signaling in the hippocampus. |
2023-06-12 |
2023-08-14 |
mouse |
| Jingyuan Ma, Feng Xiong, Zhouru Li, Guokai Dong, Xiaoming Sun, Wenjiang Yin, Hongxing Ca. The effect of chronic alcohol exposure on spatial memory and BDNF-TrkB- PLCγ1 signaling in the hippocampus of male and female mice. Heliyon. vol 9. issue 6. 2023-06-12. PMID:37303582. |
after 4 weeks of intermittent access to 20% alcohol, memory impairment in both male and female mice was evaluated using the morris water maze and the expression of bdnf, trkb, phosphorylation of plcγ1 (p-plcγ1) and plcγ1 in the hippocampus was examined using western blot. |
2023-06-12 |
2023-08-14 |
mouse |
| Jingyuan Ma, Feng Xiong, Zhouru Li, Guokai Dong, Xiaoming Sun, Wenjiang Yin, Hongxing Ca. The effect of chronic alcohol exposure on spatial memory and BDNF-TrkB- PLCγ1 signaling in the hippocampus of male and female mice. Heliyon. vol 9. issue 6. 2023-06-12. PMID:37303582. |
furthermore, after 4 weeks 20% alcohol exposure, we found significantly decreased expression levels of bdnf in the hippocampus of female mice but increased levels in male mice. |
2023-06-12 |
2023-08-14 |
mouse |
| Jingyuan Ma, Feng Xiong, Zhouru Li, Guokai Dong, Xiaoming Sun, Wenjiang Yin, Hongxing Ca. The effect of chronic alcohol exposure on spatial memory and BDNF-TrkB- PLCγ1 signaling in the hippocampus of male and female mice. Heliyon. vol 9. issue 6. 2023-06-12. PMID:37303582. |
these findings suggest that chronic alcohol exposure may induce spatial memory impairment in both sexes and opposite changes in expression of bdnf and p-plcγ1 in the hippocampus of males and females. |
2023-06-12 |
2023-08-14 |
mouse |
| Jana Tchekalarova, Desislava Krushovlieva, Petya Ivanova, Lidia Kortensk. Spontaneously hypertensive rats vs. Wistar Kyoto and Wistar rats: an assessment of anxiety, motor activity, memory performance, and seizure susceptibility. Physiology & behavior. 2023-06-12. PMID:37308045. |
in addition, the role of brain-derived neurotrophic factor (bdnf) in the hippocampus on cognitive behavior and seizure susceptibility in the three strains was evaluated. |
2023-06-12 |
2023-08-14 |
rat |
| Jana Tchekalarova, Desislava Krushovlieva, Petya Ivanova, Lidia Kortensk. Spontaneously hypertensive rats vs. Wistar Kyoto and Wistar rats: an assessment of anxiety, motor activity, memory performance, and seizure susceptibility. Physiology & behavior. 2023-06-12. PMID:37308045. |
control shr had lower bdnf expression in the hippocampus compared to wistar rats. |
2023-06-12 |
2023-08-14 |
rat |
| Jana Tchekalarova, Desislava Krushovlieva, Petya Ivanova, Lidia Kortensk. Spontaneously hypertensive rats vs. Wistar Kyoto and Wistar rats: an assessment of anxiety, motor activity, memory performance, and seizure susceptibility. Physiology & behavior. 2023-06-12. PMID:37308045. |
the results suggest wistar rats as a more appropriate control of shr than wky rats for studying memory responses mediated by bdnf in the hippocampus. |
2023-06-12 |
2023-08-14 |
rat |
| Jana Tchekalarova, Desislava Krushovlieva, Petya Ivanova, Lidia Kortensk. Spontaneously hypertensive rats vs. Wistar Kyoto and Wistar rats: an assessment of anxiety, motor activity, memory performance, and seizure susceptibility. Physiology & behavior. 2023-06-12. PMID:37308045. |
the higher vulnerability to seizures in wistar and wky rats compared to shr might be linked to ptz-induced decreased expression of bdnf in the hippocampus. |
2023-06-12 |
2023-08-14 |
rat |
| Manuela Dicarlo, Patrizia Pignataro, Roberta Zerlotin, Clelia Suriano, Chiara Zecca, Maria Teresa Dell'Abate, Giuseppina Storlino, Angela Oranger, Lorenzo Sanesi, Giorgio Mori, Maria Grano, Graziana Colaianni, Silvia Colucc. Short-Term Irisin Treatment Enhanced Neurotrophin Expression Differently in the Hippocampus and the Prefrontal Cortex of Young Mice. International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298063. |
we found significantly increased mrna levels of nerve growth factor (ngf) and fibroblast growth factor 2 (fgf-2) in the hippocampus and brain-derived growth factor (bdnf) in the pfc. |
2023-06-11 |
2023-08-14 |
mouse |
| Elena Chiavacci, Sara Bagnoli, Alessandro Cellerino, Eva Terzibasi Tozzin. Distribution of Brain-Derived Neurotrophic Factor in the Brain of the Small-Spotted Catshark International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298444. |
among the neurotrophins, brain-derived neurotrophic factor (bdnf) has the highest expression and is expressed in mammals by specific cells throughout the brain, with particularly high expression in the hippocampus and cerebral cortex. |
2023-06-11 |
2023-08-14 |
Not clear |