| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tiago M Rodrigues, André Jerónimo-Santos, Ana M Sebastião, Maria José Diógene. Adenosine A(2A) Receptors as novel upstream regulators of BDNF-mediated attenuation of hippocampal Long-Term Depression (LTD). Neuropharmacology. vol 79. 2014-12-03. PMID:24361450. |
hippocampal long-term potentiation (ltp) is facilitated by bdnf, through the activation of tropomyosin-related kinase b (trkb) receptors. |
2014-12-03 |
2023-08-12 |
rat |
| Tiago M Rodrigues, André Jerónimo-Santos, Ana M Sebastião, Maria José Diógene. Adenosine A(2A) Receptors as novel upstream regulators of BDNF-mediated attenuation of hippocampal Long-Term Depression (LTD). Neuropharmacology. vol 79. 2014-12-03. PMID:24361450. |
the present work aimed to further evaluate the effect of bdnf and trkb receptors upon ca1 hippocampal ltd and to elucidate whether this effect is under the upstream control of other signalling processes, such as the adenosine a(2a)receptors (a(2a)rs). |
2014-12-03 |
2023-08-12 |
rat |
| Tiago M Rodrigues, André Jerónimo-Santos, Ana M Sebastião, Maria José Diógene. Adenosine A(2A) Receptors as novel upstream regulators of BDNF-mediated attenuation of hippocampal Long-Term Depression (LTD). Neuropharmacology. vol 79. 2014-12-03. PMID:24361450. |
ltd, induced by a low-frequency stimulation (lfs, 900 pulses, 1 hz) in the ca1 area of rat hippocampal slices, was significantly attenuated when these slices were exposed to bdnf (60-100 ng/ml). |
2014-12-03 |
2023-08-12 |
rat |
| Gisele Pereira Dias, Mário Cesar do Nascimento Bevilaqua, Anna Claudia Domingos Silveira da Luz, Renata Lopes Fleming, Lítia Alves de Carvalho, Graham Cocks, Danielle Beckman, Lucas Costa Hosken, William de Sant'Anna Machado, Ana Carolina Corrêa-e-Castro, Felippe Mousovich-Neto, Vítor de Castro Gomes, Gilmara de Nazareth Tavares Bastos, Regina Célia Cussa Kubrusly, Vânia Maria Corrêa da Costa, Deepak Srivastava, Jesus Landeira-Fernandez, Antonio Egidio Nardi, Sandrine Thuret, Patricia Franca Gardin. Hippocampal biomarkers of fear memory in an animal model of generalized anxiety disorder. Behavioural brain research. vol 263. 2014-12-03. PMID:24462725. |
serum corticosterone levels, immunofluorescence for glucocorticoid receptors (gr) in the dentate gyrus (dg), and western blotting for hippocampal brain derived neurotrophic factor (bdnf) were performed. |
2014-12-03 |
2023-08-12 |
rat |
| Gisele Pereira Dias, Mário Cesar do Nascimento Bevilaqua, Anna Claudia Domingos Silveira da Luz, Renata Lopes Fleming, Lítia Alves de Carvalho, Graham Cocks, Danielle Beckman, Lucas Costa Hosken, William de Sant'Anna Machado, Ana Carolina Corrêa-e-Castro, Felippe Mousovich-Neto, Vítor de Castro Gomes, Gilmara de Nazareth Tavares Bastos, Regina Célia Cussa Kubrusly, Vânia Maria Corrêa da Costa, Deepak Srivastava, Jesus Landeira-Fernandez, Antonio Egidio Nardi, Sandrine Thuret, Patricia Franca Gardin. Hippocampal biomarkers of fear memory in an animal model of generalized anxiety disorder. Behavioural brain research. vol 263. 2014-12-03. PMID:24462725. |
disruption of gabaergic signaling and bdnf impairment are also proposed as part of the hippocampal mechanisms possibly underlying the anxious phenotype of this model. |
2014-12-03 |
2023-08-12 |
rat |
| Takaaki Ozawa, Kazuo Yamada, Yukio Ichitan. Hippocampal BDNF treatment facilitates consolidation of spatial memory in spontaneous place recognition in rats. Behavioural brain research. vol 263. 2014-12-03. PMID:24503120. |
hippocampal bdnf treatment facilitates consolidation of spatial memory in spontaneous place recognition in rats. |
2014-12-03 |
2023-08-12 |
rat |
| Takaaki Ozawa, Kazuo Yamada, Yukio Ichitan. Hippocampal BDNF treatment facilitates consolidation of spatial memory in spontaneous place recognition in rats. Behavioural brain research. vol 263. 2014-12-03. PMID:24503120. |
in order to investigate the role of brain-derived neurotrophic factor (bdnf) in the consolidation of spatial memory, we examined the relationship between the increase of hippocampal bdnf and the establishment of long-term spatial memory in spontaneous place recognition test in rats. |
2014-12-03 |
2023-08-12 |
rat |
| Takaaki Ozawa, Kazuo Yamada, Yukio Ichitan. Hippocampal BDNF treatment facilitates consolidation of spatial memory in spontaneous place recognition in rats. Behavioural brain research. vol 263. 2014-12-03. PMID:24503120. |
this impairment was reversed by the dorsal hippocampal bdnf treatment immediately after the sample phase, although the bdnf treatment alone did not improve performance. |
2014-12-03 |
2023-08-12 |
rat |
| Takaaki Ozawa, Kazuo Yamada, Yukio Ichitan. Hippocampal BDNF treatment facilitates consolidation of spatial memory in spontaneous place recognition in rats. Behavioural brain research. vol 263. 2014-12-03. PMID:24503120. |
results suggest an important role of hippocampal bdnf as a product of protein synthesis that is required for the consolidation of spatial memory. |
2014-12-03 |
2023-08-12 |
rat |
| Atish Prakash, Anil Kuma. Role of nuclear receptor on regulation of BDNF and neuroinflammation in hippocampus of β-amyloid animal model of Alzheimer's disease. Neurotoxicity research. vol 25. issue 4. 2014-12-01. PMID:24277156. |
role of nuclear receptor on regulation of bdnf and neuroinflammation in hippocampus of β-amyloid animal model of alzheimer's disease. |
2014-12-01 |
2023-08-12 |
rat |
| Atish Prakash, Anil Kuma. Role of nuclear receptor on regulation of BDNF and neuroinflammation in hippocampus of β-amyloid animal model of Alzheimer's disease. Neurotoxicity research. vol 25. issue 4. 2014-12-01. PMID:24277156. |
mitochondrial enzymes, oxidative parameters, inflammatory mediators (tnf-α, il-6), caspase activity, and bdnf levels were measured in the hippocampus. |
2014-12-01 |
2023-08-12 |
rat |
| Atish Prakash, Anil Kuma. Role of nuclear receptor on regulation of BDNF and neuroinflammation in hippocampus of β-amyloid animal model of Alzheimer's disease. Neurotoxicity research. vol 25. issue 4. 2014-12-01. PMID:24277156. |
icv βa-treated rats showed a memory deficit and significantly decreased bdnf level, simultaneously, increase in mitochondrial oxidative damage and inflammatory mediators in the hippocampus. |
2014-12-01 |
2023-08-12 |
rat |
| Anabel Pérez-Gómez, R Andrew Taske. Enhanced mossy fiber sprouting and synapse formation in organotypic hippocampal cultures following transient domoic acid excitotoxicity. Neurotoxicity research. vol 25. issue 4. 2014-12-01. PMID:24347374. |
we have previously reported evidence of bdnf upregulation and increased neurogenesis in rat organotypic hippocampal slice cultures (ohsc) after a transient excitotoxic injury to the hippocampal ca1 area induced by low concentrations of the ampa/kainate receptor agonist domoic acid (dom). |
2014-12-01 |
2023-08-12 |
rat |
| L Musazzi, J M Rimland, A Ieraci, G Racagni, E Domenici, M Popol. Pharmacological characterization of BDNF promoters I, II and IV reveals that serotonin and norepinephrine input is sufficient for transcription activation. The international journal of neuropsychopharmacology. vol 17. issue 5. 2014-12-01. PMID:24451568. |
we generated a gene reporter system based on hippocampal and cortical neuronal cultures, in which the transcription of luciferase is regulated by bdnf promoters i, ii, iv or by camp response element (cre), to investigate the activation of selected promoters induced by monoaminergic antidepressants and by serotonin or noradrenaline agonists. |
2014-12-01 |
2023-08-12 |
rat |
| Ying Li Gu, Li Wei Zhang, Ning Ma, Lin Lin Ye, De Xin Wang, Xu Ga. Cognitive improvement of mice induced by exercise prior to traumatic brain injury is associated with cytochrome c oxidase. Neuroscience letters. vol 570. 2014-12-01. PMID:24746931. |
using western blot, the expressions of cox i, ii, iii, bdnf, synapsin i, synaptophysin (syp) and gap43 in hippocampus of tbi mice were determinated. |
2014-12-01 |
2023-08-13 |
mouse |
| Tatiana Barichello, Jaqueline S Generoso, Lutiana R Simões, Renan A Ceretta, Diogo Dominguini, Pâmela Ferrari, Carolina Gubert, Luciano K Jornada, Josiane Budni, Flávio Kapczinski, João Queved. Vitamin B6 prevents cognitive impairment in experimental pneumococcal meningitis. Experimental biology and medicine (Maywood, N.J.). vol 239. issue 10. 2014-11-26. PMID:24903161. |
in the hippocampus, bdnf expression decreased in the meningitis group when compared to the control group; however, adjuvant treatment with vitamin b6 increased bdnf expression in the meningitis group. |
2014-11-26 |
2023-08-13 |
rat |
| Richard Kolarow, Christoph R W Kuhlmann, Thomas Munsch, Christoph Zehendner, Tanja Brigadski, Heiko J Luhmann, Volkmar Lessman. BDNF-induced nitric oxide signals in cultured rat hippocampal neurons: time course, mechanism of generation, and effect on neurotrophin secretion. Frontiers in cellular neuroscience. vol 8. 2014-11-26. PMID:25426021. |
application of exogenous bdnf, nt-4, and nt-3 (but not ngf) induced no signals in the soma and in proximal dendrites of hippocampal neurons that were sensitive to no synthase activity, trkb signaling, and intracellular calcium elevation. |
2014-11-26 |
2023-08-13 |
rat |
| Yo Shinoda, Saheeb Ahmed, Binu Ramachandran, Vinita Bharat, David Brockelt, Bekir Altas, Camin Dea. BDNF enhances spontaneous and activity-dependent neurotransmitter release at excitatory terminals but not at inhibitory terminals in hippocampal neurons. Frontiers in synaptic neuroscience. vol 6. 2014-11-26. PMID:25426063. |
bdnf enhances spontaneous and activity-dependent neurotransmitter release at excitatory terminals but not at inhibitory terminals in hippocampal neurons. |
2014-11-26 |
2023-08-13 |
rat |
| Yo Shinoda, Saheeb Ahmed, Binu Ramachandran, Vinita Bharat, David Brockelt, Bekir Altas, Camin Dea. BDNF enhances spontaneous and activity-dependent neurotransmitter release at excitatory terminals but not at inhibitory terminals in hippocampal neurons. Frontiers in synaptic neuroscience. vol 6. 2014-11-26. PMID:25426063. |
in the present study, in a direct comparison using cultured rat hippocampal neurons, we demonstrate that bdnf enhances both spontaneous and activity-dependent neurotransmitter release from excitatory terminals, but not from inhibitory terminals. |
2014-11-26 |
2023-08-13 |
rat |
| Irit Gil-Ad, Moshe Portnoy, Igor Tarasenko, Miri Bidder, Maria Kramer, Michal Taler, Abraham Weizma. A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 3. 2014-11-25. PMID:24389121. |
moreover, pgw5, but not olanzapine, attenuated phencyclidine (pcp)-induced deficits of social preference in mice and promoted the expression of brain derived neurotrophic factor (bdnf) in the hippocampus and the frontal cortex and glutamic acid decarboxylase (gad67) in the hippocampus. |
2014-11-25 |
2023-08-12 |
mouse |