| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V S Tomaz, R C Cordeiro, A M N Costa, D F de Lucena, H V Nobre Júnior, F C F de Sousa, S M M Vasconcelos, M L Vale, J Quevedo, D Macêd. Antidepressant-like effect of nitric oxide synthase inhibitors and sildenafil against lipopolysaccharide-induced depressive-like behavior in mice. Neuroscience. vol 268. 2014-12-12. PMID:24662848. |
the pretreatment with the nos inhibitors, l-name and aminoguanidine as well as sildenafil prevented the behavioral and neurochemical alterations induced by lps, although sildenafil and l-name were not able to prevent the increase in hippocampal bdnf levels induced by lps. |
2014-12-12 |
2023-08-12 |
mouse |
| Hiroyuki Otabe, Masashi Nibuya, Kuniko Shimazaki, Hiroyuki Toda, Go Suzuki, Soichiro Nomura, Kunio Shimiz. Electroconvulsive seizures enhance autophagy signaling in rat hippocampus. Progress in neuro-psychopharmacology & biological psychiatry. vol 50. 2014-12-11. PMID:24316174. |
the putative antidepressive mechanisms of a series of electroconvulsive seizures (ecs) are the following: 1) downregulation of monoaminergic receptor expression in several brain regions, 2) upregulation of the expression of brain-derived neurotrophic factor (bdnf), and 3) increased neurogenesis in the hippocampus. |
2014-12-11 |
2023-08-12 |
rat |
| Hiroyuki Otabe, Masashi Nibuya, Kuniko Shimazaki, Hiroyuki Toda, Go Suzuki, Soichiro Nomura, Kunio Shimiz. Electroconvulsive seizures enhance autophagy signaling in rat hippocampus. Progress in neuro-psychopharmacology & biological psychiatry. vol 50. 2014-12-11. PMID:24316174. |
mature bdnf (14kd) expression in the hippocampus was evaluated in order to qualify the effectiveness of the ecs or stress-loading treatment. |
2014-12-11 |
2023-08-12 |
rat |
| Indrek Heinla, Este Leidmaa, Tanel Visnapuu, Mari-Anne Philips, Eero Vasa. Enrichment and individual housing reinforce the differences in aggressiveness and amphetamine response in 129S6/SvEv and C57BL/6 strains. Behavioural brain research. vol 267. 2014-12-11. PMID:24667362. |
we measured common behavioural parameters, social behaviour and bdnf mrna expression in hippocampus and frontal cortex. |
2014-12-11 |
2023-08-12 |
mouse |
| Yi Liu, Xiaobin Fu, Nuo Lan, Sai Li, Jingzheng Zhang, Shuaishuai Wang, Cheng Li, Yanguo Shang, Tonghui Huang, Ling Zhan. Luteolin protects against high fat diet-induced cognitive deficits in obesity mice. Behavioural brain research. vol 267. 2014-12-11. PMID:24667364. |
furthermore, luteolin increased the level of brain-derived neurotrophic factor (bdnf), the action of synapsin i (syp) and postsynaptic density protein 95 (psd-95) in the cortex and hippocampus as to that the behavioral performance in morris water maze (mwm) and step-through task were significantly improved. |
2014-12-11 |
2023-08-12 |
mouse |
| Dae Young Yoo, Woosuk Kim, Dae Won Kim, Sung Min Nam, Hyo Young Jung, Jong Whi Kim, Choong Hyun Lee, Jung Hoon Choi, Moo-Ho Won, Yeo Sung Yoon, In Koo Hwan. Cell proliferation and neuroblast differentiation in the dentate gyrus of high-fat diet-fed mice are increased after rosiglitazone treatment. Journal of veterinary science. vol 15. issue 1. 2014-12-09. PMID:24136217. |
in addition, we monitored the effects of rsg on the levels of dcx and brain-derived neurotrophic factor (bdnf) in hippocampal homogenates. |
2014-12-09 |
2023-08-12 |
mouse |
| Dae Young Yoo, Woosuk Kim, Dae Won Kim, Sung Min Nam, Hyo Young Jung, Jong Whi Kim, Choong Hyun Lee, Jung Hoon Choi, Moo-Ho Won, Yeo Sung Yoon, In Koo Hwan. Cell proliferation and neuroblast differentiation in the dentate gyrus of high-fat diet-fed mice are increased after rosiglitazone treatment. Journal of veterinary science. vol 15. issue 1. 2014-12-09. PMID:24136217. |
at 8 weeks after the lfd feeding, the numbers of ki67- and dcx-positive cells as well as hippocampal levels of dcx and bdnf were significantly decreased in the rsg-treated group compared to the vehicle-treated animals. |
2014-12-09 |
2023-08-12 |
mouse |
| Dae Young Yoo, Woosuk Kim, Dae Won Kim, Sung Min Nam, Hyo Young Jung, Jong Whi Kim, Choong Hyun Lee, Jung Hoon Choi, Moo-Ho Won, Yeo Sung Yoon, In Koo Hwan. Cell proliferation and neuroblast differentiation in the dentate gyrus of high-fat diet-fed mice are increased after rosiglitazone treatment. Journal of veterinary science. vol 15. issue 1. 2014-12-09. PMID:24136217. |
in contrast, the numbers of ki67- and dcx-positive cells along with hippocampal levels of dcx and bdnf in the hfd fed mice were significantly increased in the rsg-treated mice compared to the vehicle-treated group. |
2014-12-09 |
2023-08-12 |
mouse |
| Dae Young Yoo, Woosuk Kim, Dae Won Kim, Sung Min Nam, Hyo Young Jung, Jong Whi Kim, Choong Hyun Lee, Jung Hoon Choi, Moo-Ho Won, Yeo Sung Yoon, In Koo Hwan. Cell proliferation and neuroblast differentiation in the dentate gyrus of high-fat diet-fed mice are increased after rosiglitazone treatment. Journal of veterinary science. vol 15. issue 1. 2014-12-09. PMID:24136217. |
our data demonstrate that rsg can modulate the levels of bdnf, which could play a pivotal role in cell proliferation and neuroblast differentiation in the hippocampal dentate gyrus. |
2014-12-09 |
2023-08-12 |
mouse |
| Sarah M Clark, Joseph Sand, T Chase Francis, Anitha Nagaraju, Kerry C Michael, Achsah D Keegan, Alexander Kusnecov, Todd D Gould, Leonardo H Tonell. Immune status influences fear and anxiety responses in mice after acute stress exposure. Brain, behavior, and immunity. vol 38. 2014-12-08. PMID:24524915. |
in addition, immunoblot analysis was used to assess hippocampal bdnf expression under both stressed and non-stressed conditions. |
2014-12-08 |
2023-08-12 |
mouse |
| Sarah M Clark, Joseph Sand, T Chase Francis, Anitha Nagaraju, Kerry C Michael, Achsah D Keegan, Alexander Kusnecov, Todd D Gould, Leonardo H Tonell. Immune status influences fear and anxiety responses in mice after acute stress exposure. Brain, behavior, and immunity. vol 38. 2014-12-08. PMID:24524915. |
furthermore, analysis of hippocampal bdnf indicated that rag2(-/-) mice have elevated levels of the mature form of bdnf compared to balb/c mice. |
2014-12-08 |
2023-08-12 |
mouse |
| L Pietranera, M E Brocca, P Roig, A Lima, L M Garcia-Segura, A F De Nicol. 17α-Oestradiol-induced neuroprotection in the brain of spontaneously hypertensive rats. Journal of neuroendocrinology. vol 26. issue 5. 2014-12-08. PMID:24730417. |
in the brain, we analysed steroid effects on hippocampus ki67+ proliferating cells, doublecortin (dcx) positive neuroblasts, glial fibrillary acidic protein (gfap)+ astrocyte density, aromatase immunostaining and brain-derived neurotrophic factor (bdnf) mrna. |
2014-12-08 |
2023-08-13 |
rat |
| Satoshi Okuyama, Mayu Morita, Kazuhiro Miyoshi, Yuki Nishigawa, Miki Kaji, Atsushi Sawamoto, Tsukasa Terugo, Nobuki Toyoda, Nahomi Makihata, Yoshiaki Amakura, Morio Yoshimura, Mitsunari Nakajima, Yoshiko Furukaw. 3,5,6,7,8,3',4'-Heptamethoxyflavone, a citrus flavonoid, on protection against memory impairment and neuronal cell death in a global cerebral ischemia mouse model. Neurochemistry international. vol 70. 2014-12-05. PMID:24657445. |
the results showed that hmf, administrated for three days immediately after ischemic surgery, protected against ischemia-induced memory dysfunction, rescued neuronal cell death in the ca1 cell layer, increased the production of bdnf, stimulated the autophosphorylation of camk ii and suppressed microglial activation in the hippocampus. |
2014-12-05 |
2023-08-12 |
mouse |
| Ronald S Duma. Pathophysiology of depression and innovative treatments: remodeling glutamatergic synaptic connections. Dialogues in clinical neuroscience. vol 16. issue 1. 2014-12-05. PMID:24733968. |
this is thought to occur in part via decreased expression and function of growth factors, such as brain-derived neurotrophic factor (bdnf), in the prefrontal cortex (pfc) and hippocampus. |
2014-12-05 |
2023-08-13 |
Not clear |
| Pei Jiang, Rui-Li Dang, Huan-De Li, Li-Hong Zhang, Wen-Ye Zhu, Ying Xue, Mi-Mi Tan. The impacts of swimming exercise on hippocampal expression of neurotrophic factors in rats exposed to chronic unpredictable mild stress. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-12-05. PMID:25477997. |
to systematically evaluate the potential neurotrophic factors that were involved in the antidepressive effects of exercise, in this study, we assessed the effects of swimming exercise on hippocampal mrna expression of several classes of the growth factors (bdnf, gdnf, ngf, nt-3, fgf2, vegf, and igf-1) and peptides (vgf and npy) in rats exposed to chronic unpredictable mild stress (cums). |
2014-12-05 |
2023-08-13 |
rat |
| Katarzyna Młyniec, Urszula Doboszewska, Bernadeta Szewczyk, Magdalena Sowa-Kućma, Paulina Misztak, Wojciech Piekoszewski, Franciszek Trela, Beata Ostachowicz, Gabriel Nowa. The involvement of the GPR39-Zn(2+)-sensing receptor in the pathophysiology of depression. Studies in rodent models and suicide victims. Neuropharmacology. vol 79. 2014-12-03. PMID:24333148. |
additionally, we found a decreased expression of creb, bdnf and trkb only in the hippocampus of zinc-deficient mice. |
2014-12-03 |
2023-08-12 |
mouse |
| Katarzyna Młyniec, Urszula Doboszewska, Bernadeta Szewczyk, Magdalena Sowa-Kućma, Paulina Misztak, Wojciech Piekoszewski, Franciszek Trela, Beata Ostachowicz, Gabriel Nowa. The involvement of the GPR39-Zn(2+)-sensing receptor in the pathophysiology of depression. Studies in rodent models and suicide victims. Neuropharmacology. vol 79. 2014-12-03. PMID:24333148. |
down-regulation of creb, bdnf, trkb and gpr39 receptor found under zinc-deficient conditions in the hippocampus, may play an important role in the pathophysiology of mood disorders, since most of patients suffering from depression show lower serum zinc. |
2014-12-03 |
2023-08-12 |
mouse |
| J M Malheiros, M Lima, R D T Avanzi, S Gomes da Silva, D Suchecki, R Guinsburg, L Covola. Repetitive noxious neonatal stimuli increases dentate gyrus cell proliferation and hippocampal brain-derived neurotrophic factor levels. Hippocampus. vol 24. issue 4. 2014-12-03. PMID:24339278. |
plasma corticosterone and hippocampal brain-derived neurotrophic factor (bdnf) levels were measured. |
2014-12-03 |
2023-08-12 |
rat |
| J M Malheiros, M Lima, R D T Avanzi, S Gomes da Silva, D Suchecki, R Guinsburg, L Covola. Repetitive noxious neonatal stimuli increases dentate gyrus cell proliferation and hippocampal brain-derived neurotrophic factor levels. Hippocampus. vol 24. issue 4. 2014-12-03. PMID:24339278. |
another subset was sampled for thermal response or plasma corticosterone measurement and hippocampal bdnf levels. |
2014-12-03 |
2023-08-12 |
rat |
| J M Malheiros, M Lima, R D T Avanzi, S Gomes da Silva, D Suchecki, R Guinsburg, L Covola. Repetitive noxious neonatal stimuli increases dentate gyrus cell proliferation and hippocampal brain-derived neurotrophic factor levels. Hippocampus. vol 24. issue 4. 2014-12-03. PMID:24339278. |
on the contrary, hippocampal bdnf was increased in males from both re-exposed groups. |
2014-12-03 |
2023-08-12 |
rat |