| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Simone Azevedo Bach, Letícia V de Siqueira, Alexandre P Müller, Jean P Oses, Andreia Quatrim, Tatiana Emanuelli, Lúcia Vinadé, Diogo O Souza, Júlia D Moreir. Dietary omega-3 deficiency reduces BDNF content and activation NMDA receptor and Fyn in dorsal hippocampus: implications on persistence of long-term memory in rats. Nutritional neuroscience. vol 17. issue 4. 2015-01-22. PMID:24621058. |
twelve hours after the training session, the fatty acid profile and the brain derived neurotrophic factor (bdnf) content of the dorsal hippocampus were assessed. |
2015-01-22 |
2023-08-12 |
rat |
| Simone Azevedo Bach, Letícia V de Siqueira, Alexandre P Müller, Jean P Oses, Andreia Quatrim, Tatiana Emanuelli, Lúcia Vinadé, Diogo O Souza, Júlia D Moreir. Dietary omega-3 deficiency reduces BDNF content and activation NMDA receptor and Fyn in dorsal hippocampus: implications on persistence of long-term memory in rats. Nutritional neuroscience. vol 17. issue 4. 2015-01-22. PMID:24621058. |
we also observed that the d group presented reductions in hippocampal dha (22:6 n-3) and bdnf content. |
2015-01-22 |
2023-08-12 |
rat |
| Valentina Carito, Alessandro Venditti, Armandodoriano Bianco, Mauro Ceccanti, Anna Maria Serrilli, George Chaldakov, Luigi Tarani, Sara De Nicolò, Marco Fior. Effects of olive leaf polyphenols on male mouse brain NGF, BDNF and their receptors TrkA, TrkB and p75. Natural product research. vol 28. issue 22. 2015-01-21. PMID:24865115. |
in the brain, we found decreased levels of ngf and bdnf in the hippocampus and striatum but elevated levels of ngf in the olfactory lobes and hypothalamus and again bdnf potentiation in the olfactory lobes. |
2015-01-21 |
2023-08-13 |
mouse |
| Valentina Carito, Alessandro Venditti, Armandodoriano Bianco, Mauro Ceccanti, Anna Maria Serrilli, George Chaldakov, Luigi Tarani, Sara De Nicolò, Marco Fior. Effects of olive leaf polyphenols on male mouse brain NGF, BDNF and their receptors TrkA, TrkB and p75. Natural product research. vol 28. issue 22. 2015-01-21. PMID:24865115. |
in conclusion, olive polyphenols may not only elicit an activation of the rodent olfactory system by increasing the levels of ngf and bdnf but also be stressing for the animal by reducing both the levels of hippocampal ngf/bdnf and serum gsh and increasing serum levels of ngf and bdnf. |
2015-01-21 |
2023-08-13 |
mouse |
| Natália Assaife-Lopes, Vasco C Sousa, Daniela B Pereira, Joaquim A Ribeiro, Ana M Sebastiã. Regulation of TrkB receptor translocation to lipid rafts by adenosine A(2A) receptors and its functional implications for BDNF-induced regulation of synaptic plasticity. Purinergic signalling. vol 10. issue 2. 2015-01-15. PMID:24271058. |
lipid raft integrity was also required for the effects of bdnf upon hippocampal long-term potentiation at ca1 synapses. |
2015-01-15 |
2023-08-12 |
Not clear |
| Tiffany J Mellott, Sarah M Pender, Rebecca M Burke, Erika A Langley, Jan Krzysztof Blusztaj. IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice. PloS one. vol 9. issue 4. 2015-01-15. PMID:24732467. |
igf2 also increased the protein levels of hippocampal ngf, bdnf, nt3 and igf1 and of doublecortin, a marker of neurogenesis. |
2015-01-15 |
2023-08-13 |
mouse |
| Kirstie H Stansfield, Terry Jo Bichell, Aaron B Bowman, Tomás R Guilart. BDNF and Huntingtin protein modifications by manganese: implications for striatal medium spiny neuron pathology in manganese neurotoxicity. Journal of neurochemistry. vol 131. issue 5. 2015-01-14. PMID:25099302. |
furthermore, probdnf and mature bdnf concentrations in primary cortical and hippocampal neuron cultures were decreased by exposure to mn confirming the in vivo findings. |
2015-01-14 |
2023-08-13 |
mouse |
| Zhang Tianzhu, Yang Shihai, Du Jua. Antidepressant-like effects of cordycepin in a mice model of chronic unpredictable mild stress. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2015-01-14. PMID:25587342. |
then the serotonin (5-ht) and noradrenaline (ne) concentrations in hippocampal were evaluated by hplc; tumor necrosis factor-α (tnf-α) and interleukin-6 (il-6) in hippocampal were evaluated, and the proteins of tnf-α, il-6, nf-κbp65 5-ht2a receptor (5-ht2ar), and brain-derived neurotrophic factor (bdnf) in hippocampal were evaluated by western blot. |
2015-01-14 |
2023-08-13 |
mouse |
| Zhang Tianzhu, Yang Shihai, Du Jua. Antidepressant-like effects of cordycepin in a mice model of chronic unpredictable mild stress. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2015-01-14. PMID:25587342. |
our results indicated that 6 weeks of cums exposure induced significant depression-like behavior, with low 5-ht and ne levels, high tnf-α and il-6 in brain and high hippocampal tnf-α, il-6, p-nf-κbp65, and 5-ht2ar levels, and low bdnf expression levels. |
2015-01-14 |
2023-08-13 |
mouse |
| Zhang Tianzhu, Yang Shihai, Du Jua. Antidepressant-like effects of cordycepin in a mice model of chronic unpredictable mild stress. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2015-01-14. PMID:25587342. |
besides, hippocampal bdnf expressions were also upregulated after cor treatments. |
2015-01-14 |
2023-08-13 |
mouse |
| Zhang Tianzhu, Yang Shihai, Du Jua. Antidepressant-like effects of cordycepin in a mice model of chronic unpredictable mild stress. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2015-01-14. PMID:25587342. |
in conclusion, cor remarkably improved depression-like behavior in cums mice and its antidepressant activity is mediated, at least in part, by the upregulating bdnf and downregulating 5-ht2ar levels and inflammation in hippocampus. |
2015-01-14 |
2023-08-13 |
mouse |
| R Ravenelle, H B Santolucito, E M Byrnes, J J Byrnes, S T Donaldso. Housing environment modulates physiological and behavioral responses to anxiogenic stimuli in trait anxiety male rats. Neuroscience. vol 270. 2015-01-13. PMID:24713371. |
all animals reared in ee and se had elevated brain-derived neurotrophic factor (bdnf)-positive cells in the central amygdala (cea), ca1 and ca2 hippocampal regions and the caudate putamen, but these differences were most pronounced in han rats for cea, ca1 and ca2. |
2015-01-13 |
2023-08-13 |
rat |
| R Ravenelle, H B Santolucito, E M Byrnes, J J Byrnes, S T Donaldso. Housing environment modulates physiological and behavioral responses to anxiogenic stimuli in trait anxiety male rats. Neuroscience. vol 270. 2015-01-13. PMID:24713371. |
overall, these findings suggest that environmental enrichment offers benefits for trait anxiety rats including a reduction in behavioral and physiological responses to anxiogenic stimuli and amph sensitivity, and these responses correlate with changes in bdnf expression in the central amygdala, hippocampus and the caudate putamen. |
2015-01-13 |
2023-08-13 |
rat |
| A P Ardais, M F Borges, A S Rocha, C Sallaberry, R A Cunha, L O Porciúncul. Caffeine triggers behavioral and neurochemical alterations in adolescent rats. Neuroscience. vol 270. 2015-01-13. PMID:24726984. |
caffeine (0.3-1mg/ml) increased the density of brain-derived neurotrophic factor (bdnf) and probdnf density as well as adenosine a1 receptor density in the hippocampus, whereas the higher dose of caffeine (1mg/ml) increased the density of probdnf and bdnf and decreased a1 receptor density in the cerebral cortex. |
2015-01-13 |
2023-08-13 |
rat |
| A P Ardais, M F Borges, A S Rocha, C Sallaberry, R A Cunha, L O Porciúncul. Caffeine triggers behavioral and neurochemical alterations in adolescent rats. Neuroscience. vol 270. 2015-01-13. PMID:24726984. |
these findings document an impact of caffeine consumption in adolescent rats with a dual impact on anxiety and recognition memory, associated with changes in bdnf levels and decreases of astrocytic and nerve terminal markers without overt neuronal damage in hippocampal and cortical regions. |
2015-01-13 |
2023-08-13 |
rat |
| I O Logvinov, T A Antipova, T A Gudasheva, A V Tarasiuk, P I Antipov, S B Seredeni. Neuroprotective effects of dipeptide analogue of brain-derived neurotrophic factor GSB-106 in in vitro experiments. Bulletin of experimental biology and medicine. vol 155. issue 3. 2015-01-12. PMID:24137599. |
dimeric dipeptide gsb-106, a novel structural analogue of neurotrophin bdnf, in doses from 10(-5) to 10(-8) m protected cultured immortalized mouse hippocampal ht-22 neurons from h2o2 or glutamate damage. |
2015-01-12 |
2023-08-12 |
mouse |
| Smita Thakker-Varia, Joseph Behnke, David Doobin, Vidhi Dalal, Keya Thakkar, Farah Khadim, Elizabeth Wilson, Alicia Palmieri, Hanna Antila, Tomi Rantamaki, Janet Alde. VGF (TLQP-62)-induced neurogenesis targets early phase neural progenitor cells in the adult hippocampus and requires glutamate and BDNF signaling. Stem cell research. vol 12. issue 3. 2015-01-09. PMID:24747217. |
vgf (tlqp-62)-induced neurogenesis targets early phase neural progenitor cells in the adult hippocampus and requires glutamate and bdnf signaling. |
2015-01-09 |
2023-08-13 |
mouse |
| Marco I Gonzále. Brain-derived neurotrophic factor promotes gephyrin protein expression and GABAA receptor clustering in immature cultured hippocampal cells. Neurochemistry international. vol 72. 2015-01-09. PMID:24747341. |
exogenous application of bdnf to immature neuronal cultures from rat hippocampus increased the protein levels and clustering of gephyrin. |
2015-01-09 |
2023-08-13 |
rat |
| Ming Wang, Qian Chen, Mei Li, Wei Zhou, Tengfei Ma, Yun Wang, Shuling G. Alarin-induced antidepressant-like effects and their relationship with hypothalamus-pituitary-adrenal axis activity and brain derived neurotrophic factor levels in mice. Peptides. vol 56. 2015-01-09. PMID:24768903. |
furthermore, alarin upregulated bdnf mrna levels in the prefrontal cortex and hippocampus. |
2015-01-09 |
2023-08-13 |
mouse |
| Dhananjay Bambah-Mukku, Alessio Travaglia, Dillon Y Chen, Gabriella Pollonini, Cristina M Alberin. A positive autoregulatory BDNF feedback loop via C/EBPβ mediates hippocampal memory consolidation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 37. 2015-01-07. PMID:25209292. |
a positive autoregulatory bdnf feedback loop via c/ebpβ mediates hippocampal memory consolidation. |
2015-01-07 |
2023-08-13 |
rat |