| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Francesca Calabrese, Rick H A van der Doelen, Gianluigi Guidotti, Giorgio Racagni, Tamas Kozicz, Judith R Homberg, Marco A Riv. Exposure to early life stress regulates Bdnf expression in SERT mutant rats in an anatomically selective fashion. Journal of neurochemistry. vol 132. issue 1. 2015-02-19. PMID:25087780. |
we found that both sert deletion and the ms led to an overall reduction in bdnf expression in the ventral hippocampus and the ventromedial pfc, whereas in the dorsal hippocampus and in the dorsomedial pfc, we observed a significant increase in the neurotrophin gene expression after ms exposure, specifically in the heterozygous sert rats. |
2015-02-19 |
2023-08-13 |
rat |
| Francesca Calabrese, Rick H A van der Doelen, Gianluigi Guidotti, Giorgio Racagni, Tamas Kozicz, Judith R Homberg, Marco A Riv. Exposure to early life stress regulates Bdnf expression in SERT mutant rats in an anatomically selective fashion. Journal of neurochemistry. vol 132. issue 1. 2015-02-19. PMID:25087780. |
in summary, we show that the modulation of bdnf expression in sert mutant rats exposed to ms reflects the complex functional consequences of this gene-environment interaction with a clear distinction between the ventral and the dorsal subfields of the hippocampus and of the pfc. |
2015-02-19 |
2023-08-13 |
rat |
| Francesca Calabrese, Rick H A van der Doelen, Gianluigi Guidotti, Giorgio Racagni, Tamas Kozicz, Judith R Homberg, Marco A Riv. Exposure to early life stress regulates Bdnf expression in SERT mutant rats in an anatomically selective fashion. Journal of neurochemistry. vol 132. issue 1. 2015-02-19. PMID:25087780. |
specifically, both sert deletion and the maternal separation (ms) led to an overall reduction in bdnf expression in the ventral hippocampus and in the ventromedial prefrontal cortex, whereas in the dorsal hippocampus and in the dorsomedial prefrontal cortex, we observed a significant increase in the neurotrophin gene expression after ms exposure specifically in the heterozygous sert rats. |
2015-02-19 |
2023-08-13 |
rat |
| Ya-Hsin Hsiao, Hui-Chi Hung, Shun-Hua Chen, Po-Wu Gea. Social interaction rescues memory deficit in an animal model of Alzheimer's disease by increasing BDNF-dependent hippocampal neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 49. 2015-02-19. PMID:25471562. |
the improvement was associated with increased protein and mrna levels of bdnf in the hippocampus. |
2015-02-19 |
2023-08-13 |
mouse |
| Ya-Hsin Hsiao, Hui-Chi Hung, Shun-Hua Chen, Po-Wu Gea. Social interaction rescues memory deficit in an animal model of Alzheimer's disease by increasing BDNF-dependent hippocampal neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 49. 2015-02-19. PMID:25471562. |
these results demonstrate that increased bdnf expression and neurogenesis in the hippocampus after cohousing underlie the reversal of memory deficit in app/ps1 mice. |
2015-02-19 |
2023-08-13 |
mouse |
| Qing-Qiu Mao, Zhen Huang, Xiao-Ming Zhong, Yan-Fang Xian, Siu-Po I. Piperine reverses chronic unpredictable mild stress-induced behavioral and biochemical alterations in rats. Cellular and molecular neurobiology. vol 34. issue 3. 2015-02-12. PMID:24401942. |
in addition, it was found that serotonin (5-ht) and brain-derived neurotrophic factor (bdnf) contents in the hippocampus and frontal cortex were significantly decreased in cums-treated rats. |
2015-02-12 |
2023-08-12 |
mouse |
| F Biggio, M G Pisu, A Garau, G Boero, V Locci, M C Mostallino, P Olla, C Utzeri, M Serr. Maternal separation attenuates the effect of adolescent social isolation on HPA axis responsiveness in adult rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 7. 2015-02-12. PMID:24745548. |
all experimental groups showed a significant reduction of bdnf and arc protein expression in the hippocampus. |
2015-02-12 |
2023-08-13 |
rat |
| Erica D Smith, G Aleph Prieto, Liqi Tong, Ilse Sears-Kraxberger, Jeffrey D Rice, Oswald Steward, Carl W Cotma. Rapamycin and interleukin-1β impair brain-derived neurotrophic factor-dependent neuron survival by modulating autophagy. The Journal of biological chemistry. vol 289. issue 30. 2015-02-11. PMID:24917666. |
activation of mtor is necessary for the many beneficial effects of brain-derived neurotrophic factor (bdnf), including dendritic translation and memory formation in the hippocampus. |
2015-02-11 |
2023-08-13 |
rat |
| Erica D Smith, G Aleph Prieto, Liqi Tong, Ilse Sears-Kraxberger, Jeffrey D Rice, Oswald Steward, Carl W Cotma. Rapamycin and interleukin-1β impair brain-derived neurotrophic factor-dependent neuron survival by modulating autophagy. The Journal of biological chemistry. vol 289. issue 30. 2015-02-11. PMID:24917666. |
we report that mtor activation is necessary for bdnf-dependent survival of primary rat hippocampal neurons, as either mtor inhibition by rapamycin or genetic manipulation of the downstream molecule p70s6k specifically blocked bdnf rescue. |
2015-02-11 |
2023-08-13 |
rat |
| Wenhong Dong, Zhenghao Wu, Linlin Xu, Yuehui Fang, Yajun X. Maternal supplementation of nucleotides improves the behavioral development of prenatal ethanol-exposed mice. Cognitive, affective & behavioral neuroscience. vol 14. issue 2. 2015-02-09. PMID:24146316. |
serum oxidation indexes were analyzed, and the hippocampus of each offspring was collected and detected for acetyl cholinesterase (ache) activity and the expression of p-creb, creb, and bdnf. |
2015-02-09 |
2023-08-12 |
mouse |
| Elżbieta Nowakowska, Krzysztof Kus, Piotr Ratajczak, Michał Cichocki, Anna Woźnia. The influence of aripiprazole, olanzapine and enriched environment on depressant-like behavior, spatial memory dysfunction and hippocampal level of BDNF in prenatally stressed rats. Pharmacological reports : PR. vol 66. issue 3. 2015-02-09. PMID:24905516. |
the influence of aripiprazole, olanzapine and enriched environment on depressant-like behavior, spatial memory dysfunction and hippocampal level of bdnf in prenatally stressed rats. |
2015-02-09 |
2023-08-13 |
rat |
| Elżbieta Nowakowska, Krzysztof Kus, Piotr Ratajczak, Michał Cichocki, Anna Woźnia. The influence of aripiprazole, olanzapine and enriched environment on depressant-like behavior, spatial memory dysfunction and hippocampal level of BDNF in prenatally stressed rats. Pharmacological reports : PR. vol 66. issue 3. 2015-02-09. PMID:24905516. |
it was important to determine the effect of aripiprazole ari and olanzapine ola and clarify whether the enriched environment induces increases in brain derived neurothropic factor bdnf in the hippocampus in the prenatally stressed group (psg) and non-stressed control group (nscg). |
2015-02-09 |
2023-08-13 |
rat |
| Ilaria Tonazzini, Alessandra Cecchini, Ype Elgersma, Marco Cecchin. Interaction of SH-SY5Y cells with nanogratings during neuronal differentiation: comparison with primary neurons. Advanced healthcare materials. vol 3. issue 4. 2015-02-04. PMID:24115396. |
the sh-sy5y cells' (shs) contact guidance is investigated under proliferating conditions and upon differentiation after treatment with retinoic acid (ra) and brain-derived neurotrophin factor (bdnf), and compared with mouse primary hippocampal neurons (hns). |
2015-02-04 |
2023-08-12 |
mouse |
| Tushar Dwivedi, Hui Zhan. Lithium-induced neuroprotection is associated with epigenetic modification of specific BDNF gene promoter and altered expression of apoptotic-regulatory proteins. Frontiers in neuroscience. vol 8. 2015-02-02. PMID:25642163. |
in hippocampal neurons, the effects of lithium (1 and 2 mm) on neuronal viability against glutamate-induced cytotoxicity, dendritic length and number, and expression and methylation of bdnf promoter exons and expression of apoptotic regulatory genes were studied. |
2015-02-02 |
2023-08-13 |
rat |
| André Jerónimo-Santos, Vânia L Batalha, Christa E Müller, Younis Baqi, Ana Maria Sebastião, Luisa V Lopes, Maria José Diógene. Impact of in vivo chronic blockade of adenosine A2A receptors on the BDNF-mediated facilitation of LTP. Neuropharmacology. vol 83. 2015-01-29. PMID:24747180. |
brain-derived neurotrophic factor (bdnf) through the activation of its receptor (trkb-fl) exert well-described neuroprotective effects playing a major role in hippocampal synaptic transmission and plasticity such as long-term potentiation (ltp), a molecular surrogate for learning and memory. |
2015-01-29 |
2023-08-13 |
rat |
| André Jerónimo-Santos, Vânia L Batalha, Christa E Müller, Younis Baqi, Ana Maria Sebastião, Luisa V Lopes, Maria José Diógene. Impact of in vivo chronic blockade of adenosine A2A receptors on the BDNF-mediated facilitation of LTP. Neuropharmacology. vol 83. 2015-01-29. PMID:24747180. |
the results showed that chronic blockade of a2ar in male wistar rats inhibits the facilitatory action of bdnf upon ltp on hippocampal ca1 area and decreases both mrna and protein levels of the trkb-fl receptor in hippocampus. |
2015-01-29 |
2023-08-13 |
rat |
| Yuan-Jian Yang, Yan-Kun Li, Wei Wang, Jian-Guo Wan, Bin Yu, Mei-Zhen Wang, Bin H. Small-molecule TrkB agonist 7,8-dihydroxyflavone reverses cognitive and synaptic plasticity deficits in a rat model of schizophrenia. Pharmacology, biochemistry, and behavior. vol 122. 2015-01-26. PMID:24662915. |
we found that mk-801-treated rats showed significant deficits in working learning ability and hippocampal synaptic plasticity, as well as reduction of bdnf, trkb, and phosphorylated trkb in the hippocampus. |
2015-01-26 |
2023-08-12 |
rat |
| Ayaka Miyake, Yoshihisa Kitamura, Ikuko Miyazaki, Masato Asanuma, Toshiaki Send. Effects of (+)-8-OH-DPAT on the duration of immobility during the forced swim test and hippocampal cell proliferation in ACTH-treated rats. Pharmacology, biochemistry, and behavior. vol 122. 2015-01-26. PMID:24732636. |
we then investigated the effects of (+)-8-oh-dpat on the expression of brain-derived neurotrophic factor (bdnf) and cyclin d1 (elements of cyclic adenosine monophosphate response element-binding protein (creb)-bdnf and wnt signaling pathways, respectively) in the hippocampus of saline- and acth-treated rats. |
2015-01-26 |
2023-08-13 |
rat |
| Roman Gersner, Ram Gal, Ofir Levit, Hagar Moshe, Abraham Zange. Inherited behaviors, BDNF expression and response to treatment in a novel multifactorial rat model for depression. The international journal of neuropsychopharmacology. vol 17. issue 6. 2015-01-22. PMID:24513109. |
in addition, lower bdnf levels are observed in the dorsal hippocampus of drl rats, complying with the neurotrophic hypothesis of depression. |
2015-01-22 |
2023-08-12 |
rat |
| Simone Azevedo Bach, Letícia V de Siqueira, Alexandre P Müller, Jean P Oses, Andreia Quatrim, Tatiana Emanuelli, Lúcia Vinadé, Diogo O Souza, Júlia D Moreir. Dietary omega-3 deficiency reduces BDNF content and activation NMDA receptor and Fyn in dorsal hippocampus: implications on persistence of long-term memory in rats. Nutritional neuroscience. vol 17. issue 4. 2015-01-22. PMID:24621058. |
dietary omega-3 deficiency reduces bdnf content and activation nmda receptor and fyn in dorsal hippocampus: implications on persistence of long-term memory in rats. |
2015-01-22 |
2023-08-12 |
rat |