| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lucian Hritcu, Lucian Dragos Gorga. Intranigral lipopolysaccharide induced anxiety and depression by altered BDNF mRNA expression in rat hippocampus. Progress in neuro-psychopharmacology & biological psychiatry. vol 51. 2014-11-25. PMID:24508447. |
intranigral lipopolysaccharide induced anxiety and depression by altered bdnf mrna expression in rat hippocampus. |
2014-11-25 |
2023-08-12 |
rat |
| Lucian Hritcu, Lucian Dragos Gorga. Intranigral lipopolysaccharide induced anxiety and depression by altered BDNF mRNA expression in rat hippocampus. Progress in neuro-psychopharmacology & biological psychiatry. vol 51. 2014-11-25. PMID:24508447. |
in addition, these behaviors are associated with decreased bdnf mrna expression in rat hippocampus. |
2014-11-25 |
2023-08-12 |
rat |
| Lucian Hritcu, Lucian Dragos Gorga. Intranigral lipopolysaccharide induced anxiety and depression by altered BDNF mRNA expression in rat hippocampus. Progress in neuro-psychopharmacology & biological psychiatry. vol 51. 2014-11-25. PMID:24508447. |
taken together, these data indicate that intranigral lps infusion influences the induction of bdnf mrna expression within hippocampus which contributes to observed behavioral responses in rats, with relevance for parkinson's disease conditions. |
2014-11-25 |
2023-08-12 |
rat |
| Jesper Krogh, Egill Rostrup, Carsten Thomsen, Betina Elfving, Poul Videbech, Merete Nordentof. The effect of exercise on hippocampal volume and neurotrophines in patients with major depression--a randomized clinical trial. Journal of affective disorders. vol 165. 2014-11-24. PMID:24882173. |
the effect of exercise on hippocampal volume is potentially mediated by brain derived neurotrophic factor (bdnf), vascular endothelial growth factor (vegf), and insulin like growth factor 1 (igf-1). |
2014-11-24 |
2023-08-13 |
Not clear |
| Jesper Krogh, Egill Rostrup, Carsten Thomsen, Betina Elfving, Poul Videbech, Merete Nordentof. The effect of exercise on hippocampal volume and neurotrophines in patients with major depression--a randomized clinical trial. Journal of affective disorders. vol 165. 2014-11-24. PMID:24882173. |
the aim of this trial was to assess the effect of an aerobic exercise intervention on hippocampal volume and serum bdnf, vegf, and igf-1 in patients with major depression. |
2014-11-24 |
2023-08-13 |
Not clear |
| Gabriela K Ferreira, Giselli Scaini, Isabela C Jeremias, Milena Carvalho-Silva, Cinara L Gonçalves, Talita C B Pereira, Giovanna M T Oliveira, Luiza W Kist, Maurício R Bogo, Patrícia F Schuck, Gustavo C Ferreira, Emilio L Strec. An evaluation of the effects of acute and chronic L-tyrosine administration on BDNF levels and BDNF mRNA expression in the rat brain. Molecular neurobiology. vol 49. issue 2. 2014-11-21. PMID:24091827. |
in the 30-day-old rats, we observed decreased bdnf levels without modifications in bdnf transcript level in the hippocampus and striatum. |
2014-11-21 |
2023-08-12 |
rat |
| Min Chul Lee, Randeep Rakwal, Junko Shibato, Koshiro Inoue, Hyukki Chang, Hideaki Soy. DNA microarray-based analysis of voluntary resistance wheel running reveals novel transcriptome leading robust hippocampal plasticity. Physiological reports. vol 2. issue 11. 2014-11-21. PMID:25413326. |
in two separate experiments, voluntary resistance wheel running with 30% of body weight (rwr), rather than wheel running (wr), led to greater enhancements, including adult hippocampal neurogenesis and cognitive functions, in conjunction with hippocampal brain-derived neurotrophic factor (bdnf) signaling (lee et al., j appl physiol, 2012; neurosci lett., 2013). |
2014-11-21 |
2023-08-13 |
rat |
| Grace S Griesbach, Delia L Tio, Shyama Nair, David A Hovd. Recovery of stress response coincides with responsiveness to voluntary exercise after traumatic brain injury. Journal of neurotrauma. vol 31. issue 7. 2014-11-14. PMID:24151829. |
hippocampal tissue was obtained immediately after exercise for analysis of bdnf. |
2014-11-14 |
2023-08-12 |
rat |
| Gretha J Boersma, Richard S Lee, Zachary A Cordner, Erin R Ewald, Ryan H Purcell, Alexander A Moghadam, Kellie L Tamashir. Prenatal stress decreases Bdnf expression and increases methylation of Bdnf exon IV in rats. Epigenetics. vol 9. issue 3. 2014-11-14. PMID:24365909. |
we observed decreased bdnf expression in the amygdala and hippocampus of prenatally stressed rats both at weaning and in adulthood. |
2014-11-14 |
2023-08-12 |
rat |
| Gretha J Boersma, Richard S Lee, Zachary A Cordner, Erin R Ewald, Ryan H Purcell, Alexander A Moghadam, Kellie L Tamashir. Prenatal stress decreases Bdnf expression and increases methylation of Bdnf exon IV in rats. Epigenetics. vol 9. issue 3. 2014-11-14. PMID:24365909. |
this decrease in bdnf expression was accompanied by increased dna methylation in bdnf exon iv in the amygdala and hippocampus, suggesting that pns-induced reduction in bdnf expression may, at least in part, be mediated by increased dna methylation of bdnf exon iv. |
2014-11-14 |
2023-08-12 |
rat |
| Shenghui Chu, Junfei Gu, Liang Feng, Jiping Liu, Minghua Zhang, Xiaobin Jia, Min Liu, Danian Ya. Ginsenoside Rg5 improves cognitive dysfunction and beta-amyloid deposition in STZ-induced memory impaired rats via attenuating neuroinflammatory responses. International immunopharmacology. vol 19. issue 2. 2014-11-14. PMID:24503167. |
in addition, congo red and immunohistochemistry staining results showed that rg5 alleviated aβ deposition but enhanced the expressions of insulin-like growth factors 1 (igf-1) and brain derived neurophic factor (bdnf) in the hippocampus and cerebral cortex (p<0.05). |
2014-11-14 |
2023-08-12 |
rat |
| Mikihito Kajiya, Kei Takeshita, Mizuho Kittaka, Shinji Matsuda, Kazuhisa Ouhara, Katsuhiro Takeda, Takashi Takata, Masae Kitagawa, Tsuyoshi Fujita, Hideki Shiba, Hidemi Kurihar. BDNF mimetic compound LM22A-4 regulates cementoblast differentiation via the TrkB-ERK/Akt signaling cascade. International immunopharmacology. vol 19. issue 2. 2014-11-14. PMID:24530412. |
recently, using in silico screening with a bdnf loop-domain pharmacophore, a small molecule bdnf mimetic, called lm22a-4 that can facilitate trkb signaling in hippocampal neurons to prevent cell death, was identified. |
2014-11-14 |
2023-08-12 |
human |
| Wenyu Cao, Juan Duan, Xueqin Wang, Xiaolin Zhong, Zhaolan Hu, Fulian Huang, Hongtao Wang, Juan Zhang, Fang Li, Jianyi Zhang, Xuegang Luo, Chang-Qi L. Early enriched environment induces an increased conversion of proBDNF to BDNF in the adult rat's hippocampus. Behavioural brain research. vol 265. 2014-11-13. PMID:24569010. |
early enriched environment induces an increased conversion of probdnf to bdnf in the adult rat's hippocampus. |
2014-11-13 |
2023-08-12 |
rat |
| Wenyu Cao, Juan Duan, Xueqin Wang, Xiaolin Zhong, Zhaolan Hu, Fulian Huang, Hongtao Wang, Juan Zhang, Fang Li, Jianyi Zhang, Xuegang Luo, Chang-Qi L. Early enriched environment induces an increased conversion of proBDNF to BDNF in the adult rat's hippocampus. Behavioural brain research. vol 265. 2014-11-13. PMID:24569010. |
our study aimed to explore the effects of an early-enriched environment on the conversion of probdnf to bdnf in the adult rats' hippocampus. |
2014-11-13 |
2023-08-12 |
rat |
| Wenyu Cao, Juan Duan, Xueqin Wang, Xiaolin Zhong, Zhaolan Hu, Fulian Huang, Hongtao Wang, Juan Zhang, Fang Li, Jianyi Zhang, Xuegang Luo, Chang-Qi L. Early enriched environment induces an increased conversion of proBDNF to BDNF in the adult rat's hippocampus. Behavioural brain research. vol 265. 2014-11-13. PMID:24569010. |
we found that there was no difference in the expression of probdnf in the hippocampus between the se (standard environment) and ee (enriched environment) rats, but a significantly increased bdnf protein level was found in the ee rats. |
2014-11-13 |
2023-08-12 |
rat |
| Wenyu Cao, Juan Duan, Xueqin Wang, Xiaolin Zhong, Zhaolan Hu, Fulian Huang, Hongtao Wang, Juan Zhang, Fang Li, Jianyi Zhang, Xuegang Luo, Chang-Qi L. Early enriched environment induces an increased conversion of proBDNF to BDNF in the adult rat's hippocampus. Behavioural brain research. vol 265. 2014-11-13. PMID:24569010. |
in addition, the ee resulted in a remarkably up-regulated matrix metalloproteinase-9 (mmp-9) in the hippocampus, which played a key role in converting probdnf to bdnf in the extracellular space. |
2014-11-13 |
2023-08-12 |
rat |
| Wenyu Cao, Juan Duan, Xueqin Wang, Xiaolin Zhong, Zhaolan Hu, Fulian Huang, Hongtao Wang, Juan Zhang, Fang Li, Jianyi Zhang, Xuegang Luo, Chang-Qi L. Early enriched environment induces an increased conversion of proBDNF to BDNF in the adult rat's hippocampus. Behavioural brain research. vol 265. 2014-11-13. PMID:24569010. |
these results suggested that the ee up-regulated mmp-9 levels within the hippocampus, which might facilitate the conversion of probdnf to bdnf, thereby contributing to the long lasting alterations of synaptic plasticity and behavior. |
2014-11-13 |
2023-08-12 |
rat |
| H F Sakr, K I Khalil, A M Hussein, M S A Zaki, R A Eid, M Alkhatee. Effect of dehydroepiandrosterone (DHEA) on memory and brain derived neurotrophic factor (BDNF) in a rat model of vascular dementia. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 65. issue 1. 2014-11-13. PMID:24622829. |
furthermore, the expression of brain derived neurotrophic factor (bdnf) in the hippocampus was determined. |
2014-11-13 |
2023-08-12 |
rat |
| H F Sakr, K I Khalil, A M Hussein, M S A Zaki, R A Eid, M Alkhatee. Effect of dehydroepiandrosterone (DHEA) on memory and brain derived neurotrophic factor (BDNF) in a rat model of vascular dementia. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 65. issue 1. 2014-11-13. PMID:24622829. |
treatment with dhea and donepezil increased the working and reference memories, bdnf expression as well as the central acetylcholine in the hippocampus as compared to bccao rats. |
2014-11-13 |
2023-08-12 |
rat |
| Yen Ying Lim, Victor L Villemagne, Simon M Laws, David Ames, Robert H Pietrzak, Kathryn A Ellis, Karra Harrington, Pierrick Bourgeat, Ashley I Bush, Ralph N Martins, Colin L Masters, Christopher C Rowe, Paul Maruf. Effect of BDNF Val66Met on memory decline and hippocampal atrophy in prodromal Alzheimer's disease: a preliminary study. PloS one. vol 9. issue 1. 2014-11-12. PMID:24475133. |
effect of bdnf val66met on memory decline and hippocampal atrophy in prodromal alzheimer's disease: a preliminary study. |
2014-11-12 |
2023-08-12 |
Not clear |