| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nader Maghsoudi, Rasoul Ghasemi, Zahra Ghaempanah, Ali M Ardekani, Elahe Nooshinfar, Abbas Tahzib. Effect of Chronic Restraint Stress on HPA Axis Activity and Expression of BDNF and Trkb in the Hippocampus of Pregnant Rats: Possible Contribution in Depression during Pregnancy and Postpartum Period. Basic and clinical neuroscience. vol 5. issue 2. 2014-10-22. PMID:25337371. |
brain-derived neurotrophic factor (bdnf) and its receptor, trkb, in the hippocampus are targets for adverse effects of stress paradigms; in addition, bdnf and its receptor play key role in the pathology of brain diseases like depression. |
2014-10-22 |
2023-08-13 |
rat |
| Nader Maghsoudi, Rasoul Ghasemi, Zahra Ghaempanah, Ali M Ardekani, Elahe Nooshinfar, Abbas Tahzib. Effect of Chronic Restraint Stress on HPA Axis Activity and Expression of BDNF and Trkb in the Hippocampus of Pregnant Rats: Possible Contribution in Depression during Pregnancy and Postpartum Period. Basic and clinical neuroscience. vol 5. issue 2. 2014-10-22. PMID:25337371. |
in the present study, we evaluated the possible role of hippocampal bdnf in depression during pregnancy. |
2014-10-22 |
2023-08-13 |
rat |
| O V Vetrovoĭ, T S Rybnikova, M O Samoĭlo. [Effect of hypoxic postconditioning on the expression of antiapoptotic protein Bcl-2 and neurotrophin BDNF in CA1 hippocampal field of rats surviving severe hypoxia]. Morfologiia (Saint Petersburg, Russia). vol 145. issue 2. 2014-10-17. PMID:25282819. |
[effect of hypoxic postconditioning on the expression of antiapoptotic protein bcl-2 and neurotrophin bdnf in ca1 hippocampal field of rats surviving severe hypoxia]. |
2014-10-17 |
2023-08-13 |
rat |
| O V Vetrovoĭ, T S Rybnikova, M O Samoĭlo. [Effect of hypoxic postconditioning on the expression of antiapoptotic protein Bcl-2 and neurotrophin BDNF in CA1 hippocampal field of rats surviving severe hypoxia]. Morfologiia (Saint Petersburg, Russia). vol 145. issue 2. 2014-10-17. PMID:25282819. |
using the method of quantitative immunohistochemistry, the expression of antiapoptotic protein bcl-2 and neurotrophin bdnf was studied in ca1 hippocampal field of rats that survived severe hypoxia (sh), the damaging effects of which were compensated by subsequent three postconditioning (pc) sessions of mild hypobaric hypoxia (360 mm hg, 2 hours, three times with 24 hour intervals). |
2014-10-17 |
2023-08-13 |
rat |
| Hua-ning Wang, Lei Wang, Rui-guo Zhang, Yun-chun Chen, Ling Liu, Fang Gao, Huang Nie, Wu-gang Hou, Zheng-wu Peng, Qingrong Ta. Anti-depressive mechanism of repetitive transcranial magnetic stimulation in rat: the role of the endocannabinoid system. Journal of psychiatric research. vol 51. 2014-10-14. PMID:24479995. |
hippocampal cannabinoid type i receptor (cb1) expression was measured, and the expression levels of brain-derived neurotrophic factor (bdnf), bcl-2, and bax and the number of bromodeoxyuridine (brdu)-positive cells were also investigated. |
2014-10-14 |
2023-08-12 |
rat |
| Hua-ning Wang, Lei Wang, Rui-guo Zhang, Yun-chun Chen, Ling Liu, Fang Gao, Huang Nie, Wu-gang Hou, Zheng-wu Peng, Qingrong Ta. Anti-depressive mechanism of repetitive transcranial magnetic stimulation in rat: the role of the endocannabinoid system. Journal of psychiatric research. vol 51. 2014-10-14. PMID:24479995. |
in addition, reduced hippocampal cb1 receptor, bdnf, and bcl-2/bax protein expression levels in cums rats, as well as decreased cell proliferation were also observed in the dentate gyrus. |
2014-10-14 |
2023-08-12 |
rat |
| Hua-ning Wang, Lei Wang, Rui-guo Zhang, Yun-chun Chen, Ling Liu, Fang Gao, Huang Nie, Wu-gang Hou, Zheng-wu Peng, Qingrong Ta. Anti-depressive mechanism of repetitive transcranial magnetic stimulation in rat: the role of the endocannabinoid system. Journal of psychiatric research. vol 51. 2014-10-14. PMID:24479995. |
meanwhile, rtms treatment up-regulated cell proliferation; elevated cb1 receptor, bdnf, and bcl-2/bax expression levels in the hippocampus; and ameliorated depressive-like behaviors. |
2014-10-14 |
2023-08-12 |
rat |
| Hua-ning Wang, Lei Wang, Rui-guo Zhang, Yun-chun Chen, Ling Liu, Fang Gao, Huang Nie, Wu-gang Hou, Zheng-wu Peng, Qingrong Ta. Anti-depressive mechanism of repetitive transcranial magnetic stimulation in rat: the role of the endocannabinoid system. Journal of psychiatric research. vol 51. 2014-10-14. PMID:24479995. |
these results indicate that rtms increases bdnf production and hippocampal cell proliferation to protect against cums-induced changes through its effect on cb1 receptors. |
2014-10-14 |
2023-08-12 |
rat |
| Emmanouil Rizos, Matilda A Papathanasiou, Panagiota G Michalopoulou, Efstathios Laskos, Aggeliki Mazioti, Anastasia Kastania, Konstantina Vasilopoulou, Paraskevi Nikolaidou, Dimitrios Margaritis, Charalabos Papageorgiou, Ioannis Liappa. A longitudinal study of alterations of hippocampal volumes and serum BDNF levels in association to atypical antipsychotics in a sample of first-episode patients with schizophrenia. PloS one. vol 9. issue 2. 2014-10-14. PMID:24551075. |
a longitudinal study of alterations of hippocampal volumes and serum bdnf levels in association to atypical antipsychotics in a sample of first-episode patients with schizophrenia. |
2014-10-14 |
2023-08-12 |
Not clear |
| Emmanouil Rizos, Matilda A Papathanasiou, Panagiota G Michalopoulou, Efstathios Laskos, Aggeliki Mazioti, Anastasia Kastania, Konstantina Vasilopoulou, Paraskevi Nikolaidou, Dimitrios Margaritis, Charalabos Papageorgiou, Ioannis Liappa. A longitudinal study of alterations of hippocampal volumes and serum BDNF levels in association to atypical antipsychotics in a sample of first-episode patients with schizophrenia. PloS one. vol 9. issue 2. 2014-10-14. PMID:24551075. |
however it is unclear whether treatment with antipsychotics is associated with alterations of hippocampal volume and bdnf levels. |
2014-10-14 |
2023-08-12 |
Not clear |
| Nina N Karpova, Jesse Saku Olavi Lindholm, Natalia Kulesskaya, Natalia Onishchenko, Marie Vahter, Dina Popova, Sandra Ceccatelli, Eero Castré. TrkB overexpression in mice buffers against memory deficits and depression-like behavior but not all anxiety- and stress-related symptoms induced by developmental exposure to methylmercury. Frontiers in behavioral neuroscience. vol 8. 2014-10-13. PMID:25309367. |
developmental exposure to low dose of methylmercury (mehg) has a long-lasting effect on memory and attention deficits in humans, as well as cognitive performance, depression-like behavior and the hippocampal levels of the brain-derived neurotrophic factor (bdnf)in mice. |
2014-10-13 |
2023-08-13 |
mouse |
| Nina N Karpova, Jesse Saku Olavi Lindholm, Natalia Kulesskaya, Natalia Onishchenko, Marie Vahter, Dina Popova, Sandra Ceccatelli, Eero Castré. TrkB overexpression in mice buffers against memory deficits and depression-like behavior but not all anxiety- and stress-related symptoms induced by developmental exposure to methylmercury. Frontiers in behavioral neuroscience. vol 8. 2014-10-13. PMID:25309367. |
these changes were associated with tk+ effect on the increase in bdnf 2, 3, 4 and 6 transcription in the hippocampus as well as with interaction of tk+ and mehg factors for bdnf 1, 9a and truncated trkb.t1 transcripts in the prefrontal cortex. |
2014-10-13 |
2023-08-13 |
mouse |
| Nina N Karpova, Jesse Saku Olavi Lindholm, Natalia Kulesskaya, Natalia Onishchenko, Marie Vahter, Dina Popova, Sandra Ceccatelli, Eero Castré. TrkB overexpression in mice buffers against memory deficits and depression-like behavior but not all anxiety- and stress-related symptoms induced by developmental exposure to methylmercury. Frontiers in behavioral neuroscience. vol 8. 2014-10-13. PMID:25309367. |
these tk genotype-independent changes were primarily accompanied by the mehg-induced hippocampal deficits in the activity-dependent bdnf 1, 4 and 9a variants, trkb.t1, and transcripts for important antioxidant enzymes glyoxalases glo1 and glo2 and glutathione reductase gsr. |
2014-10-13 |
2023-08-13 |
mouse |
| Anne-Laure Dinel, Caroline André, Agnès Aubert, Guillaume Ferreira, Sophie Layé, Nathalie Castano. Lipopolysaccharide-induced brain activation of the indoleamine 2,3-dioxygenase and depressive-like behavior are impaired in a mouse model of metabolic syndrome. Psychoneuroendocrinology. vol 40. 2014-10-09. PMID:24485475. |
moreover, this was associated with an impaired effect of lps on hippocampal expression of the brain-derived neurotrophic factor (bdnf) that contributes to mood regulation, including under inflammatory conditions. |
2014-10-09 |
2023-08-12 |
mouse |
| Min-Kyoo Shin, Hong-Gi Kim, Seung-Hyun Baek, Woo-Ram Jung, Dong-Ik Park, Jong-Sung Park, Dong-Gyu Jo, Kil-Lyong Ki. Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques. Neurobiology of aging. vol 35. issue 5. 2014-10-06. PMID:24268884. |
neuropep-1 treatment markedly increases hippocampal and cortical bdnf levels. |
2014-10-06 |
2023-08-12 |
mouse |
| Anna Effenberg, Alexander Klein, Robbin Gibb, Cathy Carroll, Wolfgang Baumgärtner, Claudia Grothe, Andreas Ratzk. Adult hemiparkinsonian rats do not benefit from tactile stimulation. Behavioural brain research. vol 261. 2014-10-06. PMID:24342749. |
in contrast ts applied to healthy rats elicited a transient short-term increase of fgf2 in the striatum and bdnf, grin1, and fgf2 in the hippocampus. |
2014-10-06 |
2023-08-12 |
rat |
| Priya Balasubramanian, Madhan Subramanian, Joseph L Nunez, Sheba M J Mohankumar, P S Mohankuma. Chronic estradiol treatment decreases brain derived neurotrophic factor (BDNF) expression and monoamine levels in the amygdala--implications for behavioral disorders. Behavioural brain research. vol 261. 2014-10-06. PMID:24361909. |
because alterations in brain-derived neurotrophic factor (bdnf) and monoamine levels in the hippocampus and amygdala have been associated with anxiety disorders, we hypothesized that chronic treatment with a low dose of estradiol would cause anxiety-like disorder by altering bdnf and monoamine levels in these regions. |
2014-10-06 |
2023-08-12 |
rat |
| Qing-Qiu Mao, Zhen Huang, Xiao-Ming Zhong, Yan-Fang Xian, Siu-Po I. Brain-derived neurotrophic factor signalling mediates the antidepressant-like effect of piperine in chronically stressed mice. Behavioural brain research. vol 261. 2014-10-06. PMID:24361910. |
it was also found that bdnf protein expression in the hippocampus and frontal cortex were significantly decreased in cums-treated mice. |
2014-10-06 |
2023-08-12 |
mouse |
| Qing-Qiu Mao, Zhen Huang, Xiao-Ming Zhong, Yan-Fang Xian, Siu-Po I. Brain-derived neurotrophic factor signalling mediates the antidepressant-like effect of piperine in chronically stressed mice. Behavioural brain research. vol 261. 2014-10-06. PMID:24361910. |
in parallel, chronic piperine treatment significantly increased bdnf protein expression in the hippocampus and frontal cortex of both naive and cums-treated mice. |
2014-10-06 |
2023-08-12 |
mouse |
| Shuzhen Kong, Zhihua Cheng, Jianhui Liu, Yun Wan. Downregulated GABA and BDNF-TrkB pathway in chronic cyclothiazide seizure model. Neural plasticity. vol 2014. 2014-10-06. PMID:24757570. |
in addition, both bdnf and its receptor trkb were also decreased in hippocampus of the chronic ctz seizure rats. |
2014-10-06 |
2023-08-13 |
rat |