| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shuzhen Kong, Zhihua Cheng, Jianhui Liu, Yun Wan. Downregulated GABA and BDNF-TrkB pathway in chronic cyclothiazide seizure model. Neural plasticity. vol 2014. 2014-10-06. PMID:24757570. |
in addition, both bdnf and its receptor trkb were also decreased in hippocampus of the chronic ctz seizure rats. |
2014-10-06 |
2023-08-13 |
rat |
| Miyoung Yang, Juhwan Kim, Joong-Sun Kim, Sung-Ho Kim, Jong-Choon Kim, Man-Jong Kang, Uhee Jung, Taekyun Shin, Hongbing Wang, Changjong Moo. Hippocampal dysfunctions in tumor-bearing mice. Brain, behavior, and immunity. vol 36. 2014-10-02. PMID:24513875. |
behavioral alterations were examined; stress-related parameters measured; hippocampal neurogenesis evaluated; and the levels of pro-inflammatory cytokines, brain-derived neurotrophic factor (bdnf) and cyclooxygenase-2 (cox-2) assayed, 2 weeks after inoculation of adult balb/c mice with cells of a colon carcinoma cell line (ct26). |
2014-10-02 |
2023-08-12 |
mouse |
| Miyoung Yang, Juhwan Kim, Joong-Sun Kim, Sung-Ho Kim, Jong-Choon Kim, Man-Jong Kang, Uhee Jung, Taekyun Shin, Hongbing Wang, Changjong Moo. Hippocampal dysfunctions in tumor-bearing mice. Brain, behavior, and immunity. vol 36. 2014-10-02. PMID:24513875. |
additionally, the adrenal glands became enlarged, and the numbers of ki-67-positive proliferating hippocampal cells and doublecortin-positive immature progenitor neurons, as well as the constitutive levels of mrnas encoding bdnf and cox-2 were significantly reduced. |
2014-10-02 |
2023-08-12 |
mouse |
| Miyoung Yang, Juhwan Kim, Joong-Sun Kim, Sung-Ho Kim, Jong-Choon Kim, Man-Jong Kang, Uhee Jung, Taekyun Shin, Hongbing Wang, Changjong Moo. Hippocampal dysfunctions in tumor-bearing mice. Brain, behavior, and immunity. vol 36. 2014-10-02. PMID:24513875. |
therefore, a peripheral tumor alone may be sufficient to induce hippocampal dysfunction, possibly by reducing the rate of neurogenesis and the levels of bdnf and cox-2 in that tissue and also by increasing stress-related parameters and the circulating levels of pro-inflammatory cytokines. |
2014-10-02 |
2023-08-12 |
mouse |
| Charles Francisco Ferreira, Juliana Rombaldi Bernardi, Rachel Krolow, Danusa Mar Arcego, Gabriel Rodrigo Fries, Bianca Wollenhaupt de Aguiar, Gabrielle Senter, Flávio Pereira Kapczinski, Patrícia Pelufo Silveira, Carla Dalma. Vulnerability to dietary n-3 polyunsaturated fatty acid deficiency after exposure to early stress in rats. Pharmacology, biochemistry, and behavior. vol 107. 2014-09-30. PMID:23537731. |
the aim of this study was to examine the interaction between variations in the early environment (handling or maternal separation) and the chronic exposure to a nutritional n-3 pufa deficiency on locomotor activity, sucrose preference, forced swimming test and on serum and hippocampal brain-derived neurotrophic factor (bdnf) levels. |
2014-09-30 |
2023-08-12 |
rat |
| Charles Francisco Ferreira, Juliana Rombaldi Bernardi, Rachel Krolow, Danusa Mar Arcego, Gabriel Rodrigo Fries, Bianca Wollenhaupt de Aguiar, Gabrielle Senter, Flávio Pereira Kapczinski, Patrícia Pelufo Silveira, Carla Dalma. Vulnerability to dietary n-3 polyunsaturated fatty acid deficiency after exposure to early stress in rats. Pharmacology, biochemistry, and behavior. vol 107. 2014-09-30. PMID:23537731. |
we observed that early life environment and a mild n-3 pufa deficiency are able to affect several behavioral aspects (food and sucrose consumption and locomotor response), and lead to a differential hippocampal bdnf metabolism in adult life. |
2014-09-30 |
2023-08-12 |
rat |
| Jennifer Larimore, Pearl V Ryder, Kun-Yong Kim, L Alex Ambrose, Christopher Chapleau, Gaston Calfa, Christina Gross, Gary J Bassell, Lucas Pozzo-Miller, Yoland Smith, Konrad Talbot, In-Hyun Park, Victor Faunde. MeCP2 regulates the synaptic expression of a Dysbindin-BLOC-1 network component in mouse brain and human induced pluripotent stem cell-derived neurons. PloS one. vol 8. issue 6. 2014-09-29. PMID:23750231. |
pallidin immunoreactivity decreased concomitantly with reduced bdnf content in the hippocampus of mecp2 mice. |
2014-09-29 |
2023-08-12 |
mouse |
| Jennifer Larimore, Pearl V Ryder, Kun-Yong Kim, L Alex Ambrose, Christopher Chapleau, Gaston Calfa, Christina Gross, Gary J Bassell, Lucas Pozzo-Miller, Yoland Smith, Konrad Talbot, In-Hyun Park, Victor Faunde. MeCP2 regulates the synaptic expression of a Dysbindin-BLOC-1 network component in mouse brain and human induced pluripotent stem cell-derived neurons. PloS one. vol 8. issue 6. 2014-09-29. PMID:23750231. |
similarly, bdnf content was reduced in the hippocampus of bloc-1 deficient mice suggesting that genetic defects in bloc-1 are upstream of the bdnf phenotype in mecp2 deficient mice. |
2014-09-29 |
2023-08-12 |
mouse |
| Xuan Liu, Junjian Zhang, Dong Sun, Yuanteng Fan, Hongbin Zhou, Binfang F. Effects of fluoxetine on brain-derived neurotrophic factor serum concentration and cognition in patients with vascular dementia. Clinical interventions in aging. vol 9. 2014-09-29. PMID:24648723. |
selective serotonin reuptake inhibitors improve cognition in patients with stroke and increase the expression of brain-derived neurotrophic factor (bdnf) in the rat hippocampus. |
2014-09-29 |
2023-08-12 |
rat |
| Lifeng Zhang, Cuihong Jin, Xiaobo Lu, Jinghua Yang, Shengwen Wu, Qiufang Liu, Rong Chen, Chunyu Bai, Di Zhang, Linlin Zheng, Yanqiu Du, Yuan Ca. Aluminium chloride impairs long-term memory and downregulates cAMP-PKA-CREB signalling in rats. Toxicology. vol 323. 2014-09-26. PMID:24973631. |
hippocampal camp, cpka, pcreb, bdnf and c-jun expression decreased significantly, and the neuronal and synaptic ultrastructure exhibited pathological changes after al treatment. |
2014-09-26 |
2023-08-13 |
rat |
| Maria José Diógenes, Raquel Neves-Tomé, Sergio Fucile, Katiuscia Martinello, Maria Scianni, Panos Theofilas, Jan Lopatár, Joaquim A Ribeiro, Laura Maggi, Bruno G Frenguelli, Cristina Limatola, Detlev Boison, Ana M Sebastiã. Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase. Cerebral cortex (New York, N.Y. : 1991). vol 24. issue 1. 2014-09-25. PMID:22997174. |
we demonstrate that adk: 1) critically influences the basal tone of adenosine, evaluated by microelectrode adenosine biosensors, and its release following stimulation; 2) determines the degree of tonic adenosine-dependent synaptic inhibition, which correlates with differential plasticity at hippocampal synapses with low release probability; 3) modulates the age-dependent effects of bdnf on hippocampal synaptic transmission, an action dependent upon co-activation of adenosine a2a receptors; and 4) influences gabaa receptor-mediated currents in ca3 pyramidal neurons. |
2014-09-25 |
2023-08-12 |
mouse |
| G S Kirshenbaum, C R Burgess, N Déry, M Fahnestock, J H Peever, J C Rode. Attenuation of mania-like behavior in Na(+),K(+)-ATPase α3 mutant mice by prospective therapies for bipolar disorder: melatonin and exercise. Neuroscience. vol 260. 2014-09-25. PMID:24342563. |
the effect of melatonin on sleep and the effect of exercise on brain-derived neurotrophic factor (bdnf) expression in the hippocampus were assayed. |
2014-09-25 |
2023-08-12 |
mouse |
| G S Kirshenbaum, C R Burgess, N Déry, M Fahnestock, J H Peever, J C Rode. Attenuation of mania-like behavior in Na(+),K(+)-ATPase α3 mutant mice by prospective therapies for bipolar disorder: melatonin and exercise. Neuroscience. vol 260. 2014-09-25. PMID:24342563. |
myk/+ showed higher baseline levels of bdnf protein in the hippocampus than +/+. |
2014-09-25 |
2023-08-12 |
mouse |
| G S Kirshenbaum, C R Burgess, N Déry, M Fahnestock, J H Peever, J C Rode. Attenuation of mania-like behavior in Na(+),K(+)-ATPase α3 mutant mice by prospective therapies for bipolar disorder: melatonin and exercise. Neuroscience. vol 260. 2014-09-25. PMID:24342563. |
exercise increased bdnf protein in +/+ hippocampus, while it did not significantly affect bdnf levels in myk/+ hippocampus. |
2014-09-25 |
2023-08-12 |
mouse |
| G S Kirshenbaum, C R Burgess, N Déry, M Fahnestock, J H Peever, J C Rode. Attenuation of mania-like behavior in Na(+),K(+)-ATPase α3 mutant mice by prospective therapies for bipolar disorder: melatonin and exercise. Neuroscience. vol 260. 2014-09-25. PMID:24342563. |
our results also suggest that hippocampal bdnf may not mediate the effects of exercise on mania-related behavior in the myk/+ model of mania. |
2014-09-25 |
2023-08-12 |
mouse |
| K Sakata, S M Duk. Lack of BDNF expression through promoter IV disturbs expression of monoamine genes in the frontal cortex and hippocampus. Neuroscience. vol 260. 2014-09-25. PMID:24345476. |
lack of bdnf expression through promoter iv disturbs expression of monoamine genes in the frontal cortex and hippocampus. |
2014-09-25 |
2023-08-12 |
mouse |
| K Sakata, S M Duk. Lack of BDNF expression through promoter IV disturbs expression of monoamine genes in the frontal cortex and hippocampus. Neuroscience. vol 260. 2014-09-25. PMID:24345476. |
our results provide causal evidence that lack of promoter iv-driven bdnf disturbs expression of monoaminergic genes in the frontal cortex and hippocampus. |
2014-09-25 |
2023-08-12 |
mouse |
| G Ramírez-Rodríguez, M A Ocaña-Fernández, N M Vega-Rivera, O M Torres-Pérez, A Gómez-Sánchez, E Estrada-Camarena, L Ortiz-Lópe. Environmental enrichment induces neuroplastic changes in middle age female Balb/c mice and increases the hippocampal levels of BDNF, p-Akt and p-MAPK1/2. Neuroscience. vol 260. 2014-09-25. PMID:24361917. |
environmental enrichment induces neuroplastic changes in middle age female balb/c mice and increases the hippocampal levels of bdnf, p-akt and p-mapk1/2. |
2014-09-25 |
2023-08-12 |
mouse |
| Xiu-Ping Sun, Zhe Shi, Rui-Le Pan, Chuan Qin, Yong-Liang Zhang, Ying-Hui Li, Li-Na Qu, Teng-Fei Li, Xin-Min Li. Antidepressant-like effects and mechanism of action of SYG in depression model in rats. Neuro endocrinology letters. vol 35. issue 2. 2014-09-25. PMID:24878971. |
the mechanism underlying the antidepressant-like action was investigated by exploring bdnf signaling way in the hippocampus. |
2014-09-25 |
2023-08-13 |
rat |
| Ulrich Rabl, Bernhard M Meyer, Kersten Diers, Lucie Bartova, Andreas Berger, Dominik Mandorfer, Ana Popovic, Christian Scharinger, Julia Huemer, Klaudius Kalcher, Gerald Pail, Helmuth Haslacher, Thomas Perkmann, Christian Windischberger, Burkhard Brocke, Harald H Sitte, Daniela D Pollak, Jean-Claude Dreher, Siegfried Kasper, Nicole Praschak-Rieder, Ewald Moser, Harald Esterbauer, Lukas Pezawa. Additive gene-environment effects on hippocampal structure in healthy humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 30. 2014-09-22. PMID:25057194. |
the present mri study investigated interaction effects on hippocampal volume between three well-studied functional genetic variants (comt val158met, bdnf val66met, 5-httlpr) associated with hippocampal volume and a measure of environmental adversity (life events questionnaire) in a large sample of healthy humans (n = 153). |
2014-09-22 |
2023-08-13 |
Not clear |