| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hui Lu, Hyungju Park, Mu-Ming Po. Spike-timing-dependent BDNF secretion and synaptic plasticity. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1633. 2014-08-11. PMID:24298135. |
in acute hippocampal slices, we found that the presence of extracellular brain-derived neurotrophic factor (bdnf) is essential for the induction of spike-timing-dependent long-term potentiation (tltp). |
2014-08-11 |
2023-08-12 |
Not clear |
| Hui Lu, Hyungju Park, Mu-Ming Po. Spike-timing-dependent BDNF secretion and synaptic plasticity. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1633. 2014-08-11. PMID:24298135. |
to determine whether bdnf could be secreted from postsynaptic dendrites in a spike-timing-dependent manner, we used a reduced system of dissociated hippocampal neurons in culture. |
2014-08-11 |
2023-08-12 |
Not clear |
| Hui Lu, Hyungju Park, Mu-Ming Po. Spike-timing-dependent BDNF secretion and synaptic plasticity. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1633. 2014-08-11. PMID:24298135. |
by monitoring changes in the green fluorescent protein (gfp) fluorescence at the dendrite of hippocampal neurons expressing gfp-tagged bdnf, we found that pairing of iontophoretic glutamate pulses with neuronal spiking resulted in bdnf secretion from the dendrite at the iontophoretic site only when the glutamate pulses were applied within a time window of approximately 40 ms prior to neuronal spiking, consistent with the timing requirement of synaptic potentiation via stdp. |
2014-08-11 |
2023-08-12 |
Not clear |
| Tristan J Will, Georgi Tushev, Lisa Kochen, Belquis Nassim-Assir, Ivan J Cajigas, Susanne Tom Dieck, Erin M Schuma. Deep sequencing and high-resolution imaging reveal compartment-specific localization of Bdnf mRNA in hippocampal neurons. Science signaling. vol 6. issue 306. 2014-08-08. PMID:24345682. |
deep sequencing and high-resolution imaging reveal compartment-specific localization of bdnf mrna in hippocampal neurons. |
2014-08-08 |
2023-08-12 |
rat |
| Tristan J Will, Georgi Tushev, Lisa Kochen, Belquis Nassim-Assir, Ivan J Cajigas, Susanne Tom Dieck, Erin M Schuma. Deep sequencing and high-resolution imaging reveal compartment-specific localization of Bdnf mRNA in hippocampal neurons. Science signaling. vol 6. issue 306. 2014-08-08. PMID:24345682. |
we performed 3' end sequencing on rat hippocampal slices and detected two isoforms of bdnf containing either a short or a long 3' untranslated region (3'utr). |
2014-08-08 |
2023-08-12 |
rat |
| Tristan J Will, Georgi Tushev, Lisa Kochen, Belquis Nassim-Assir, Ivan J Cajigas, Susanne Tom Dieck, Erin M Schuma. Deep sequencing and high-resolution imaging reveal compartment-specific localization of Bdnf mRNA in hippocampal neurons. Science signaling. vol 6. issue 306. 2014-08-08. PMID:24345682. |
bdnf mrna was present in the somatic compartment of rat hippocampal slices or the somata of cultured rat hippocampal neurons but was rarely detected in the dendritic processes. |
2014-08-08 |
2023-08-12 |
rat |
| Tristan J Will, Georgi Tushev, Lisa Kochen, Belquis Nassim-Assir, Ivan J Cajigas, Susanne Tom Dieck, Erin M Schuma. Deep sequencing and high-resolution imaging reveal compartment-specific localization of Bdnf mRNA in hippocampal neurons. Science signaling. vol 6. issue 306. 2014-08-08. PMID:24345682. |
pharmacological stimulation of hippocampal neurons induced bdnf expression but did not change the ratio of bdnf isoform abundance. |
2014-08-08 |
2023-08-12 |
rat |
| Tristan J Will, Georgi Tushev, Lisa Kochen, Belquis Nassim-Assir, Ivan J Cajigas, Susanne Tom Dieck, Erin M Schuma. Deep sequencing and high-resolution imaging reveal compartment-specific localization of Bdnf mRNA in hippocampal neurons. Science signaling. vol 6. issue 306. 2014-08-08. PMID:24345682. |
the findings indicate that endogenous bdnf mrna, although weakly abundant, is primarily localized to the somatic compartment of hippocampal neurons. |
2014-08-08 |
2023-08-12 |
rat |
| Graciano Leal, Diogo Comprido, Carlos B Duart. BDNF-induced local protein synthesis and synaptic plasticity. Neuropharmacology. vol 76 Pt C. 2014-08-06. PMID:23602987. |
brain-derived neurotrophic factor (bdnf) is an important regulator of synaptic transmission and long-term potentiation (ltp) in the hippocampus and in other brain regions, playing a role in the formation of certain forms of memory. |
2014-08-06 |
2023-08-12 |
Not clear |
| Graciano Leal, Diogo Comprido, Carlos B Duart. BDNF-induced local protein synthesis and synaptic plasticity. Neuropharmacology. vol 76 Pt C. 2014-08-06. PMID:23602987. |
the role of bdnf in ltp is best studied in the hippocampus, where the neurotrophin acts at pre- and post-synaptic levels. |
2014-08-06 |
2023-08-12 |
Not clear |
| Helen E Scharfman, Neil J MacLusk. Differential regulation of BDNF, synaptic plasticity and sprouting in the hippocampal mossy fiber pathway of male and female rats. Neuropharmacology. vol 76 Pt C. 2014-08-06. PMID:23660230. |
differential regulation of bdnf, synaptic plasticity and sprouting in the hippocampal mossy fiber pathway of male and female rats. |
2014-08-06 |
2023-08-12 |
rat |
| Helen E Scharfman, Neil J MacLusk. Differential regulation of BDNF, synaptic plasticity and sprouting in the hippocampal mossy fiber pathway of male and female rats. Neuropharmacology. vol 76 Pt C. 2014-08-06. PMID:23660230. |
many studies have described potent effects of bdnf, 17β-estradiol or androgen on hippocampal synapses and their plasticity. |
2014-08-06 |
2023-08-12 |
rat |
| Helen E Scharfman, Neil J MacLusk. Differential regulation of BDNF, synaptic plasticity and sprouting in the hippocampal mossy fiber pathway of male and female rats. Neuropharmacology. vol 76 Pt C. 2014-08-06. PMID:23660230. |
far less information is available about the interactions between 17β-estradiol and bdnf in hippocampus, or interactions between androgen and bdnf in hippocampus. |
2014-08-06 |
2023-08-12 |
rat |
| Helen E Scharfman, Neil J MacLusk. Differential regulation of BDNF, synaptic plasticity and sprouting in the hippocampal mossy fiber pathway of male and female rats. Neuropharmacology. vol 76 Pt C. 2014-08-06. PMID:23660230. |
here we review the regulation of bdnf in the mossy fiber pathway, a critical part of hippocampal circuitry. |
2014-08-06 |
2023-08-12 |
rat |
| Ipe Nina. Synaptic regulation of affective behaviors; role of BDNF. Neuropharmacology. vol 76 Pt C. 2014-08-06. PMID:23747574. |
remarkably, studies in humans with a single nucleotide polymorphism in the bdnf gene, the bdnf val66met which affects regulated release of bdnf, showed profound deficits in hippocampal and prefrontal cortical (pfc) plasticity and cognitive behaviors. |
2014-08-06 |
2023-08-12 |
Not clear |
| Tyra S C Zetterström, Alexander A Coppell, Ahmad A Khundaka. The role of 5-hydroxytryptamine receptor subtypes in the regulation of brain-derived neurotrophic factor gene expression. The Journal of pharmacy and pharmacology. vol 66. issue 1. 2014-08-05. PMID:24341949. |
the study aims to investigate the role of 5-hydroxytryptamine receptor subtypes in mediating the inhibitory effect of the selective serotonin reuptake inhibitor (fluoxetine on brain-derived neurotrophic factor gene (bdnf) expression in rat hippocampus. |
2014-08-05 |
2023-08-12 |
rat |
| Yu-Lung Lin, Sabrina Wan. Prenatal lipopolysaccharide exposure increases depression-like behaviors and reduces hippocampal neurogenesis in adult rats. Behavioural brain research. vol 259. 2014-08-04. PMID:24177209. |
in the present study we used forced swim test and chronic mild stress challenge to assess depression-like behaviors in the affected offspring and examined their adult hippocampal neurogenesis and brain-derived neurotrophic factor (bdnf) concentration. |
2014-08-04 |
2023-08-12 |
rat |
| Todd M Darlington, Riley D McCarthy, Ryan J Cox, Marissa A Ehringe. Mesolimbic transcriptional response to hedonic substitution of voluntary exercise and voluntary ethanol consumption. Behavioural brain research. vol 259. 2014-08-04. PMID:24239693. |
hippocampal bdnf mrna increased in response to exercise and decreased in response to ethanol. |
2014-08-04 |
2023-08-12 |
mouse |
| Andrew S Whiteman, Daniel E Young, Xuemei He, Tai C Chen, Robert C Wagenaar, Chantal E Stern, Karin Scho. Interaction between serum BDNF and aerobic fitness predicts recognition memory in healthy young adults. Behavioural brain research. vol 259. 2014-08-04. PMID:24269495. |
among these factors, glucocorticoids, brain derived neurotrophic factor (bdnf), insulin-like growth factor-1 (igf-1), and vascular endothelial growth factor (vegf), hormones that have considerable and diverse physiological importance, are thought to effect normal and exercise-induced hippocampal plasticity. |
2014-08-04 |
2023-08-12 |
human |
| Andrew S Whiteman, Daniel E Young, Xuemei He, Tai C Chen, Robert C Wagenaar, Chantal E Stern, Karin Scho. Interaction between serum BDNF and aerobic fitness predicts recognition memory in healthy young adults. Behavioural brain research. vol 259. 2014-08-04. PMID:24269495. |
our results may suggest an exercise adaptation-related change in the bdnf dose-response curve that relates to hippocampal memory. |
2014-08-04 |
2023-08-12 |
human |