| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christiane D Wrann, James P White, John Salogiannnis, Dina Laznik-Bogoslavski, Jun Wu, Di Ma, Jiandie D Lin, Michael E Greenberg, Bruce M Spiegelma. Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway. Cell metabolism. vol 18. issue 5. 2014-06-05. PMID:24120943. |
exercise induces hippocampal bdnf through a pgc-1α/fndc5 pathway. |
2014-06-05 |
2023-08-12 |
mouse |
| Christiane D Wrann, James P White, John Salogiannnis, Dina Laznik-Bogoslavski, Jun Wu, Di Ma, Jiandie D Lin, Michael E Greenberg, Bruce M Spiegelma. Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway. Cell metabolism. vol 18. issue 5. 2014-06-05. PMID:24120943. |
importantly, peripheral delivery of fndc5 to the liver via adenoviral vectors, resulting in elevated blood irisin, induces expression of bdnf and other neuroprotective genes in the hippocampus. |
2014-06-05 |
2023-08-12 |
mouse |
| Baoji X. BDNF (I)rising from exercise. Cell metabolism. vol 18. issue 5. 2014-06-05. PMID:24206660. |
exercise produces many beneficial effects on brain health, in part by increasing hippocampal bdnf levels; however, the mechanism underlying bdnf gene regulation remains unknown. |
2014-06-05 |
2023-08-12 |
Not clear |
| Baoji X. BDNF (I)rising from exercise. Cell metabolism. vol 18. issue 5. 2014-06-05. PMID:24206660. |
(2013) show that exercise induces hippocampal bdnf expression by stimulating expression of fndc5, the precursor of irisin, via the transcriptional complex pgc-1α/errα. |
2014-06-05 |
2023-08-12 |
Not clear |
| Xiafeng Shen, Aiping Li, Yuling Zhang, Xiaomin Dong, Tian Shan, Yi Wu, Jie Jia, Yongshan H. The effect of different intensities of treadmill exercise on cognitive function deficit following a severe controlled cortical impact in rats. International journal of molecular sciences. vol 14. issue 11. 2014-06-03. PMID:24185909. |
the brain-derived neurotrophic factor (bdnf) and p-creb protein levels in the contralateral hippocampus were increased significantly in the low intensity exercise group. |
2014-06-03 |
2023-08-12 |
rat |
| Xiafeng Shen, Aiping Li, Yuling Zhang, Xiaomin Dong, Tian Shan, Yi Wu, Jie Jia, Yongshan H. The effect of different intensities of treadmill exercise on cognitive function deficit following a severe controlled cortical impact in rats. International journal of molecular sciences. vol 14. issue 11. 2014-06-03. PMID:24185909. |
our results suggest that 2 weeks of low intensity of treadmill exercise is beneficial for improving cognitive function and increasing hippocampal bdnf expression after a severe tbi in its early phase. |
2014-06-03 |
2023-08-12 |
rat |
| Sun Hong, Yu Xin, Wu HaiQin, Zhang GuiLian, Zhang Ru, Zhan ShuQin, Wang HuQing, Yao Li, Bu Ning, Li YongNa. The PPARγ agonist rosiglitazone prevents neuronal loss and attenuates development of spontaneous recurrent seizures through BDNF/TrkB signaling following pilocarpine-induced status epilepticus. Neurochemistry international. vol 63. issue 5. 2014-06-02. PMID:23927864. |
in the present study, the pparγ agonist rosiglitazone inhibited increases in bdnf and trkb after status epilepticus (se), and also prevented hippocampal neuronal loss. |
2014-06-02 |
2023-08-12 |
Not clear |
| Walaiporn Tongjaroenbuangam, Nootchanart Ruksee, Thanutchaporn Mahanam, Piyarat Govitrapon. Melatonin attenuates dexamethasone-induced spatial memory impairment and dexamethasone-induced reduction of synaptic protein expressions in the mouse brain. Neurochemistry international. vol 63. issue 5. 2014-06-02. PMID:24036059. |
furthermore, dex reduced brain-derived neurotrophic factor (bdnf), n-methyl-d-aspartate (nmda) receptor subunit (nr2a/b), calcium/calmodulin-dependent protein kinase ii (camkii) in both the prefrontal cortex and hippocampus and synaptophysin in the prefrontal cortex. |
2014-06-02 |
2023-08-12 |
mouse |
| Young-Je Si. Treadmill exercise alleviates impairment of spatial learning ability through enhancing cell proliferation in the streptozotocin-induced Alzheimer's disease rats. Journal of exercise rehabilitation. vol 10. issue 2. 2014-05-30. PMID:24877042. |
decreased cell proliferation with decrement of bdnf and trkb expressions in the hippocampus were observed in the stz-induced alzheimer's disease rats. |
2014-05-30 |
2023-08-13 |
rat |
| S Migliarini, G Pacini, B Pelosi, G Lunardi, M Pasqualett. Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation. Molecular psychiatry. vol 18. issue 10. 2014-05-29. PMID:23007167. |
finally, we demonstrated that bdnf expression is significantly up-regulated in the hippocampus of mice lacking brain 5-ht, mirroring the timing of the appearance of hyperinnervation and thus unmasking a possible regulatory feedback mechanism tuning the serotonergic neuronal circuitry formation. |
2014-05-29 |
2023-08-12 |
mouse |
| Bombi Lee, Insop Shim, Hyejung Lee, Dae-Hyun Hah. Fucoidan prevents depression-like behavior in rats exposed to repeated restraint stress. Journal of natural medicines. vol 67. issue 3. 2014-05-22. PMID:23090005. |
administration of fcn also significantly blocked the increase in th expression in the locus coeruleus and the basolateral nucleus of the amygdala, and the decrease in bdnf mrna expression in the hippocampus. |
2014-05-22 |
2023-08-12 |
rat |
| Bombi Lee, Bongjun Sur, Insop Shim, Hyejung Lee, Dae-Hyun Hah. Baicalin improves chronic corticosterone-induced learning and memory deficits via the enhancement of impaired hippocampal brain-derived neurotrophic factor and cAMP response element-binding protein expression in the rat. Journal of natural medicines. vol 68. issue 1. 2014-05-21. PMID:23749289. |
the effect of bai on the hippocampal expression of brain-derived neurotrophic factor (bdnf) and camp response element-binding protein (creb) was also investigated. |
2014-05-21 |
2023-08-12 |
rat |
| Bombi Lee, Bongjun Sur, Insop Shim, Hyejung Lee, Dae-Hyun Hah. Baicalin improves chronic corticosterone-induced learning and memory deficits via the enhancement of impaired hippocampal brain-derived neurotrophic factor and cAMP response element-binding protein expression in the rat. Journal of natural medicines. vol 68. issue 1. 2014-05-21. PMID:23749289. |
additionally, as assessed by immunohistochemistry and reverse transcription-polymerase chain reaction (rt-pcr) analysis, the administration of bai also significantly alleviated memory-associated decreases in the expression levels of bdnf and creb proteins and mrnas in the hippocampus. |
2014-05-21 |
2023-08-12 |
rat |
| Giselli Scaini, Clarissa M Comim, Giovanna M T Oliveira, Matheus A B Pasquali, João Quevedo, Daniel P Gelain, José Cláudio F Moreira, Patrícia F Schuck, Gustavo C Ferreira, Maurício R Bogo, Emilio L Strec. Chronic administration of branched-chain amino acids impairs spatial memory and increases brain-derived neurotrophic factor in a rat model. Journal of inherited metabolic disease. vol 36. issue 5. 2014-05-19. PMID:23109061. |
our results demonstrated an increase in bdnf in the hippocampus and cerebral cortex, accompanied by memory impairment in spatial memory tasks. |
2014-05-19 |
2023-08-12 |
rat |
| Yeonghoon Son, Miyoung Yang, Joong-Sun Kim, Juhwan Kim, Sung-Ho Kim, Jong-Choon Kim, Taekyun Shin, Hongbing Wang, Sung-Kee Jo, Uhee Jung, Changjong Moo. Hippocampal dysfunction during the chronic phase following a single exposure to cranial irradiation. Experimental neurology. vol 254. 2014-05-19. PMID:24491956. |
additionally, hippocampal neurogenesis, inflammatory cytokines, inducible nitric oxide synthase (inos), cyclooxygenase-2 (cox-2), brain-derived neurotrophic factor (bdnf), and glial cell line-derived neurotrophic factor (gdnf) were analyzed. |
2014-05-19 |
2023-08-12 |
mouse |
| Yeonghoon Son, Miyoung Yang, Joong-Sun Kim, Juhwan Kim, Sung-Ho Kim, Jong-Choon Kim, Taekyun Shin, Hongbing Wang, Sung-Kee Jo, Uhee Jung, Changjong Moo. Hippocampal dysfunction during the chronic phase following a single exposure to cranial irradiation. Experimental neurology. vol 254. 2014-05-19. PMID:24491956. |
the reduction in the chronic phase was consistent with the significant down-regulation in the mrna expression of inos, cox-2, bdnf, and gdnf in the hippocampus. |
2014-05-19 |
2023-08-12 |
mouse |
| Patrick Pla, Sophie Orvoen, Caroline Benstaali, Sophie Dodier, Alain M Gardier, Denis J David, Sandrine Humbert, Frédéric Saudo. Huntingtin acts non cell-autonomously on hippocampal neurogenesis and controls anxiety-related behaviors in adult mouse. PloS one. vol 8. issue 9. 2014-05-16. PMID:24019939. |
our data suggest that these non-cell autonomous effects are linked to defects in both bdnf transport and release upon htt silencing in hippocampal neurons, and in bdnf/trkb signaling. |
2014-05-16 |
2023-08-12 |
mouse |
| Melissa M Kaczmarczyk, Agnieszka S Machaj, Gabriel S Chiu, Marcus A Lawson, Stephen J Gainey, Jason M York, Daryl D Meling, Stephen A Martin, Kristin A Kwakwa, Andrew F Newman, Jeffrey A Woods, Keith W Kelley, Yanyan Wang, Michael J Miller, Gregory G Freun. Methylphenidate prevents high-fat diet (HFD)-induced learning/memory impairment in juvenile mice. Psychoneuroendocrinology. vol 38. issue 9. 2014-05-14. PMID:23411461. |
examination of mouse cortex, hippocampus and hypothalamus for dopamine and its metabolites demonstrated increased homovanillic acid (hva) concentrations in the hippocampus and cortex that were associated with decreased cortical bdnf gene expression. |
2014-05-14 |
2023-08-12 |
mouse |
| Fumio Soeda, Emi Hirakawa, Masako Inoue, Tetsuya Shirasaki, Kazuo Takaham. Cloperastine rescues impairment of passive avoidance response in mice prenatally exposed to diethylstilbestrol. Environmental toxicology. vol 29. issue 2. 2014-05-12. PMID:22223406. |
in addition, cloperastine affected the levels of 5-ht1a receptors, girk and bdnf in the hippocampus of des-exposed mice. |
2014-05-12 |
2023-08-12 |
mouse |
| Deepika Suri, Vandana Veenit, Ambalika Sarkar, Devi Thiagarajan, Arvind Kumar, Eric J Nestler, Sanjeev Galande, Vidita A Vaidy. Early stress evokes age-dependent biphasic changes in hippocampal neurogenesis, BDNF expression, and cognition. Biological psychiatry. vol 73. issue 7. 2014-05-09. PMID:23237316. |
early stress evokes age-dependent biphasic changes in hippocampal neurogenesis, bdnf expression, and cognition. |
2014-05-09 |
2023-08-12 |
Not clear |