| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H G Liu, G X Hong, F B Wang, F Che. Motoneurotrophins derived from limb buds protect the motoneurons in anterior spinal cord after nerve injury and promote nerve regeneration. Brain research. vol 800. issue 2. 1998-09-04. PMID:9685649. |
at 1 day, 4 days, 1 week, 2 weeks, 4 weeks and 6 weeks post surgery, the content of acetylcholine esterase (ache) and acid phosphatase (acp) of the anterior spinal cord (injured side) was quantified, and the corresponding motoneuron's ultrastructure and the existant ratio were also examined. |
1998-09-04 |
2023-08-12 |
rat |
| A Marín Burgin, L Szczupa. Basal acetylcholine release in leech ganglia depolarizes neurons through receptors with a nicotinic binding site. The Journal of experimental biology. vol 201. issue Pt 12. 1998-08-24. PMID:9722429. |
the results suggest the existence of a basal level of acetylcholine (ach) release in the leech ganglion that is powerfully counteracted by endogenous ache activity. |
1998-08-24 |
2023-08-12 |
Not clear |
| S R Pereira, G A Menezes, G C Franco, A E Costa, A M Ribeir. Chronic ethanol consumption impairs spatial remote memory in rats but does not affect cortical cholinergic parameters. Pharmacology, biochemistry, and behavior. vol 60. issue 2. 1998-08-17. PMID:9632211. |
moreover, there were no significant differences between treated and control subjects in the following biochemical brain cortical parameters: in vitro acetylcholinesterase (ache) activity, and stimulated acetylcholine (ach) release. |
1998-08-17 |
2023-08-12 |
human |
| R N Sachdev, S M Lu, R G Wiley, F F Ebne. Role of the basal forebrain cholinergic projection in somatosensory cortical plasticity. Journal of neurophysiology. vol 79. issue 6. 1998-07-17. PMID:9636120. |
the immunotoxin reduces acetylcholine esterase (ache)-positive fibers in s1 cortex by >90% by 3 wk after injection. |
1998-07-17 |
2023-08-12 |
rat |
| B Garrone, M R Luparini, L Tolu, M Magnani, C Landolfi, C Milanes. Effect of the subchronic treatment with the acetylcholinesterase inhibitor heptastigmine on central cholinergic transmission and memory impairment in aged rats. Neuroscience letters. vol 245. issue 1. 1998-07-14. PMID:9596354. |
the effect of subchronic administration of the acetylcholinesterase (ache) inhibitor heptastigmine (hep 0.6 mg/kg s.c. daily for 15 days) was investigated on cortical extracellular acetylcholine (ach) levels and on memory function in aged male rats (26 months old at the beginning of the experiments) using microdialysis and behavioural techniques. |
1998-07-14 |
2023-08-12 |
rat |
| R C Choi, L Y Yung, T T Dong, D C Wan, Y H Wong, K W Tsi. The calcitonin gene-related peptide-induced acetylcholinesterase synthesis in cultured chick myotubes is mediated by cyclic AMP. Journal of neurochemistry. vol 71. issue 1. 1998-07-09. PMID:9648861. |
in vertebrate neuromuscular junctions, post-synaptic specialization includes aggregation of acetylcholine receptors (achrs) and acetylcholinesterase (ache). |
1998-07-09 |
2023-08-12 |
chicken |
| W Yao, D A Godfre. Immunohistochemical evaluation of cholinergic neurons in the rat superior olivary complex. Microscopy research and technique. vol 41. issue 3. 1998-07-02. PMID:9605344. |
the cholinergic system in the rat superior olivary complex (soc) was evaluated by immunohistochemistry for choline acetyltransferase (chat) and vesicular acetylcholine transporter (vacht) and histochemistry for acetylcholinesterase (ache). |
1998-07-02 |
2023-08-12 |
rat |
| L A Zimmer, M Ennis, R G Wiley, M T Shiple. Nerve gas-induced seizures: role of acetylcholine in the rapid induction of Fos and glial fibrillary acidic protein in piriform cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 10. 1998-06-01. PMID:9570817. |
this suggests that the inhibition of ache by soman leads to increased acetylcholine (ach) and neuronal excitability in pc. |
1998-06-01 |
2023-08-12 |
rat |
| M A Prendergast, A V Terry, J J Buccafusc. Effects of chronic, low-level organophosphate exposure on delayed recall, discrimination, and spatial learning in monkeys and rats. Neurotoxicology and teratology. vol 20. issue 2. 1998-05-14. PMID:9536457. |
chronic exposure to low levels of organophosphate (op) compounds impairs acetylcholine (ach) degradation by acetylcholinesterase (ache) and, in humans, may produce lasting neurotoxicity affecting cognitive function. |
1998-05-14 |
2023-08-12 |
rat |
| Y Chen, E Shohami, R Bass, M Weinstoc. Cerebro-protective effects of ENA713, a novel acetylcholinesterase inhibitor, in closed head injury in the rat. Brain research. vol 784. issue 1-2. 1998-04-30. PMID:9518537. |
ischemia decreases brain acetylcholine (ach) levels and head trauma upregulates acetylcholinesterase (ache) in experimental animal models. |
1998-04-30 |
2023-08-12 |
rat |
| J Liu, C N Pop. Comparative presynaptic neurochemical changes in rat striatum following exposure to chlorpyrifos or parathion. Journal of toxicology and environmental health. Part A. vol 53. issue 7. 1998-04-30. PMID:9561967. |
the relative effects of either vehicle (peanut oil, 2 ml/kg, sc), cpf (280 mg/kg), or ps (6.6 mg/kg) on clinical signs of toxicity and ache activity, high-affinity choline uptake (hacu), and potassium-evoked acetylcholine (ach) release in striatum were examined for a 7-d period after exposure in adult female sprague-dawley rats. |
1998-04-30 |
2023-08-12 |
rat |
| M Alkondon, E F Pereira, W S Cortes, A Maelicke, E X Albuquerqu. Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517478. |
in the present study, we demonstrate that choline, a precursor of acetylcholine (ach) and a product of acetylcholine hydrolysis by acetylcholinesterase (ache), acts as an efficient and relatively selective agonist of alpha7-containing nicotinic acetylcholine receptors (nachr) in neurons cultured from the rat hippocampus, olfactory bulb and thalamus as well as in pc12 cells. |
1998-04-24 |
2023-08-12 |
rat |
| C Opazo, N C Inestros. Crosslinking of amyloid-beta peptide to brain acetylcholinesterase. Molecular and chemical neuropathology. vol 33. issue 1. 1998-04-21. PMID:9493175. |
acetylcholinesterase (ache) is the enzyme responsible for the hydrolysis of the neurotransmitter acetylcholine in the central nervous system. |
1998-04-21 |
2023-08-12 |
Not clear |
| O Niwa, T Horiuchi, R Kurita, K Torimits. On-line electrochemical sensor for selective continuous measurement of acetylcholine in cultured brain tissue. Analytical chemistry. vol 70. issue 6. 1998-04-15. PMID:9530003. |
carbon electrodes were modified with an acetylcholine esterase (ache), choline oxidase (chox), and osmium poly(vinylpyridine)-based redox polymer containing horseradish peroxidase (os-gel-hrp). |
1998-04-15 |
2023-08-12 |
rat |
| J Thome, K Nara, P Foley, T Michel, W Gsell, W Retz, M Rosler, P Riedere. Ciliary neurotrophic factor (CNTF) genotypes: influence on choline acetyltransferase (ChAT) and acetylcholine esterase (AChE) activities and neurotrophin 3 (NT3) concentration in human post mortem brain tissue. Journal fur Hirnforschung. vol 38. issue 4. 1998-03-31. PMID:9476208. |
ciliary neurotrophic factor (cntf) genotypes: influence on choline acetyltransferase (chat) and acetylcholine esterase (ache) activities and neurotrophin 3 (nt3) concentration in human post mortem brain tissue. |
1998-03-31 |
2023-08-12 |
human |
| J Thome, K Nara, P Foley, T Michel, W Gsell, W Retz, M Rosler, P Riedere. Ciliary neurotrophic factor (CNTF) genotypes: influence on choline acetyltransferase (ChAT) and acetylcholine esterase (AChE) activities and neurotrophin 3 (NT3) concentration in human post mortem brain tissue. Journal fur Hirnforschung. vol 38. issue 4. 1998-03-31. PMID:9476208. |
we therefore conducted an explorative pilot study to investigate the influence of a null mutation allele of the cntf gene on chat (choline acetyltransferase) and ache (acetylcholine esterase) activities in various regions of human post mortem brain tissue. |
1998-03-31 |
2023-08-12 |
human |
| J M Cermak, T Holler, D A Jackson, J K Blusztaj. Prenatal availability of choline modifies development of the hippocampal cholinergic system. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 12. issue 3. 1998-03-31. PMID:9506479. |
to characterize the neurochemical mechanisms that may mediate this effect, we investigated the development of indices of the cholinergic system in the hippocampus: choline acetyltransferase (chat), acetylcholinesterase (ache), synthesis of acetylcholine (ach) from choline transported by high-affinity choline uptake (hacu), and potassium-evoked ach release. |
1998-03-31 |
2023-08-12 |
rat |
| M Brank, K Zajc-Kreft, S Kreft, R Komel, Z Grubi. Biogenesis of acetylcholinesterase is impaired, although its mRNA level remains normal, in the glucocorticoid-treated rat skeletal muscle. European journal of biochemistry. vol 251. issue 1-2. 1998-03-23. PMID:9492307. |
acetylcholinesterase (ache) is responsible for the hydrolysis of acetylcholine in the neuromuscular junction and other cholinergic synapses. |
1998-03-23 |
2023-08-12 |
rat |
| E Acquas, H C Fibige. Dopaminergic regulation of striatal acetylcholine release: the critical role of acetylcholinesterase inhibition. Journal of neurochemistry. vol 70. issue 3. 1998-03-12. PMID:9489729. |
this study examined the effects of different levels of acetylcholinesterase (ache) inhibition on dopaminergic regulation of striatal acetylcholine (ach) release as estimated by in vivo brain microdialysis. |
1998-03-12 |
2023-08-12 |
Not clear |
| S Gralewic. [Possible consequences of AChE inhibition in organophosphate poisoning. A new approach to an old problem]. Medycyna pracy. vol 48. issue 4. 1998-02-18. PMID:9471495. |
the known function of ache is hydrolysis of the neurotransmitter, acetylcholine (ach). |
1998-02-18 |
2023-08-12 |
Not clear |