| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Z Huang, R Villarta-Snow, G J Lubrano, G G Guilbaul. Development of choline and acetylcholine Pt microelectrodes. Analytical biochemistry. vol 215. issue 1. 1994-02-28. PMID:8297012. |
choline (ch) and acetylcholine (ach) microenzyme sensors were developed based on the immobilization of choline oxidase (cho) and acetylcholinesterase (ache) at the tip of a 25-micron pt wire sealed in glass. |
1994-02-28 |
2023-08-12 |
Not clear |
| S Yamad. [The effects of lesions in the medial septal area to spatial learning in rats]. Fukuoka igaku zasshi = Hukuoka acta medica. vol 84. issue 11. 1994-02-10. PMID:8276343. |
acetylcholine esterase (ache) activity was persistently depleted in the hippocampus by the msa lesion. |
1994-02-10 |
2023-08-12 |
rat |
| A D Wolfe, P K Chiang, B P Doctor, N Fryar, J P Rhee, M Saee. Monoclonal antibody AE-2 modulates carbamate and organophosphate inhibition of fetal bovine serum acetylcholinesterase. Molecular pharmacology. vol 44. issue 6. 1994-01-26. PMID:8264551. |
the monoclonal antibody ae-2, raised against the human erythrocyte acetylcholinesterase (ache) dimer (acetylcholine acetylhydrolase, ec 3.1.1.7), binds to other mammalian aches, including the tetramer that occurs in fetal bovine serum (fbs). |
1994-01-26 |
2023-08-12 |
human |
| S Bursztajn, Y J Jong, S A Berma. Differential distribution of vesicular carriers during differentiation and synapse formation. Journal of cellular biochemistry. vol 53. issue 3. 1994-01-25. PMID:8263042. |
both acetylcholine receptors (achr) and acetylcholinesterase (ache) are transported via coated vesicles, some of which accumulate beneath the neuromuscular synapse where achrs cluster. |
1994-01-25 |
2023-08-12 |
mouse |
| A G Pogorelov, Budantsev AYu, V N Pogorelov. Quantitative electron probe microanalysis of acetylcholinesterase activity in rat brain sections. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 41. issue 12. 1993-12-30. PMID:8245428. |
this reaction is based on the hydrolysis of acetylcholine substrate with ache. |
1993-12-30 |
2023-08-12 |
rat |
| B L Schlaggar, J A De Carlos, D D O'Lear. Acetylcholinesterase as an early marker of the differentiation of dorsal thalamus in embryonic rats. Brain research. Developmental brain research. vol 75. issue 1. 1993-12-10. PMID:8222210. |
the enzyme acetylcholinesterase (ache) is transiently expressed in rats by neurons of the principal sensory thalamic nuclei, although these neurons do not use acetylcholine as a neurotransmitter. |
1993-12-10 |
2023-08-12 |
rat |
| F Amenta, F Franch, A Ricci, J A Veg. Cholinergic neurotransmission in the hippocampus of aged rats: influence of L-alpha-glycerylphosphorylcholine treatment. Annals of the New York Academy of Sciences. vol 695. 1993-12-10. PMID:8239302. |
the influence of aging and of l-alpha-glycerylphosphorylcholine (gfc) treatment on the acetylcholine synthesizing and degradating enzymes choline acetyltransferase (chat) and acetylcholinesterase (ache) and on cholinergic muscarinic m-1 and m-2 receptors were assessed in the hippocampus using immunocytochemical, histochemical and radioligand binding techniques, respectively. |
1993-12-10 |
2023-08-12 |
rat |
| M K Lakshmana, T Desiraju, T R Raj. Mercuric chloride-induced alterations of levels of noradrenaline, dopamine, serotonin and acetylcholine esterase activity in different regions of rat brain during postnatal development. Archives of toxicology. vol 67. issue 6. 1993-11-09. PMID:8215912. |
levels of noradrenaline (na), dopamine (da), 5-hydroxytryptamine (5-ht) and the activity of acetylcholine esterase (ache) were assayed in various brain regions in different age groups. |
1993-11-09 |
2023-08-12 |
rat |
| S de la Porte, F Ragueh, B Eymard, P Courbin, J Chapron, J Koeni. Effect of sera from myasthenia gravis patients and of alpha-bungarotoxin on acetylcholinesterase during in vitro neuromuscular synaptogenesis. Journal of the neurological sciences. vol 117. issue 1-2. 1993-11-01. PMID:8410074. |
to clarify the relationship between the mechanisms of ache concentration during synaptogenesis and achr concentration, we compared the effect of mg sera (receptors are internalised and degraded) and of the acetylcholine antagonist alpha-bungarotoxin (non-functional receptors are still present in the muscular membrane). |
1993-11-01 |
2023-08-12 |
Not clear |
| N Suneetha, R P Kuma. Ultrasound-induced enhancement of ACh, AChE and GABA in fetal brain tissue of mouse. Ultrasound in medicine & biology. vol 19. issue 5. 1993-09-23. PMID:8356785. |
the neurotransmitters, acetylcholine (ach) and gamma amino butyric acid (gaba), and the associated enzyme acetylcholinesterase (ache) levels, were estimated in the exposed fetal brains. |
1993-09-23 |
2023-08-12 |
mouse |
| J L Sussman, M Harel, I Silma. Three-dimensional structure of acetylcholinesterase and of its complexes with anticholinesterase drugs. Chemico-biological interactions. vol 87. issue 1-3. 1993-09-03. PMID:8343975. |
based on our recent x-ray crystallographic determination of the structure of acetylcholinesterase (ache) from torpedo californica, we can see for the first time, at atomic resolution, a protein binding pocket for the neurotransmitter, acetylcholine. |
1993-09-03 |
2023-08-12 |
Not clear |
| S R Babu, S M Somani, S N Dub. Effect of physostigmine and exercise on choline acetyltransferase and acetylcholinesterase activities in fast and slow muscles of rat. Pharmacology, biochemistry, and behavior. vol 45. issue 3. 1993-08-19. PMID:8332628. |
our results suggest that phy and exercise has significant effect on the synthetic (chat) and degradative (ache) enzymes of acetylcholine in active edl muscle. |
1993-08-19 |
2023-08-12 |
rat |
| S Itabashi, T Ohrui, K Sekizawa, Y Matsuzaki, H Sasak. Peripheral airway hyperresponsiveness in the choline-deficiently fed rat. Respiration physiology. vol 92. issue 2. 1993-08-06. PMID:8327793. |
rats fed with choline-deficient diets are known as a model of aging and learning impairments due to acetylcholine (ach) deficiency in the brain which may be associated with a decrease in acetylcholinesterase (ache; ec 3.1.1.7). |
1993-08-06 |
2023-08-12 |
rat |
| Y Kawato, M Sekiguchi, K Akahane, Y Tsutomi, Y Hirota, H Kuga, W Suzuki, H Hakusui, K Sat. Inhibitory activity of camptothecin derivatives against acetylcholinesterase in dogs and their binding activity to acetylcholine receptors in rats. The Journal of pharmacy and pharmacology. vol 45. issue 5. 1993-07-22. PMID:8099964. |
in the present study, we investigated the activities of camptothecin derivatives in inhibiting acetylcholinesterase (ache) and in binding to muscarinic acetylcholine receptors (achr). |
1993-07-22 |
2023-08-12 |
rat |
| S Sasho, H Obase, S Ichikawa, T Kitazawa, H Nonaka, R Yoshizaki, A Ishii, K Shut. Synthesis of 2-imidazolidinylidenepropanedinitrile derivatives as stimulators of gastrointestinal motility. Journal of medicinal chemistry. vol 36. issue 5. 1993-06-24. PMID:8496937. |
ranitidine (1), the histamine h2-receptor antagonist, has been previously reported to increase gastric emptying and gastric motility by inhibition of acetylcholinesterase (ache) and enhancement of acetylcholine (ach) release. |
1993-06-24 |
2023-08-12 |
Not clear |
| N O Sjöstrand, S D Beckett, E Kling. Nervous regulation of the tone of the retractor penis muscle in the goat. Acta physiologica Scandinavica. vol 147. issue 4. 1993-06-17. PMID:8388153. |
the noradrenaline (na) and acetylcholine (ach) content of the rp was determined, and histochemistry for adrenergic and acetylcholinesterase (ache) positive nerves was performed. |
1993-06-17 |
2023-08-12 |
Not clear |
| J Salamoun, J Remie. Indirect detection of anti-acetylcholinesterase compounds in microcolumn liquid chromatography using packed bed reactor with immobilized human red blood cell acetylcholinesterase and choline oxidase. Journal of pharmaceutical and biomedical analysis. vol 10. issue 10-12. 1993-05-07. PMID:1298399. |
a home-made packed bed microbioreactor system containing immobilized enzyme acetylcholinesterase (ache) in human red blood cell membrane and choline oxidase (cho) from alcaligenes was used for the post-column conversion of acetylcholine to hydrogen peroxide which was detected by an electrochemical detector. |
1993-05-07 |
2023-08-11 |
human |
| T N Nagaraja, T Desiraj. Effects of chronic consumption of metanil yellow by developing and adult rats on brain regional levels of noradrenaline, dopamine and serotonin, on acetylcholine esterase activity and on operant conditioning. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 31. issue 1. 1993-04-06. PMID:8095244. |
regional levels of noradrenaline, dopamine and serotonin, activity of acetylcholine esterase (ache), and operant conditioning with food reward were assessed in rats fed, metanil yellow and in controls. |
1993-04-06 |
2023-08-12 |
rat |
| K K Kunjilwar, J Behar. Effect of amplitude-modulated radio frequency radiation on cholinergic system of developing rats. Brain research. vol 601. issue 1-2. 1993-03-17. PMID:8431780. |
decrease in acetylcholine esterase (ache) activity was independent of carrier wave frequencies. |
1993-03-17 |
2023-08-12 |
rat |
| G H Sterling, P H Doukas, C Jackson, R Caccese, K J O'Neill, J J O'Neil. 3-Carbamyl-N-allylquinuclidinium bromide. Effects on cholinergic activity and protection against soman. Biochemical pharmacology. vol 45. issue 2. 1993-03-16. PMID:8435096. |
the results demonstrate that reversible inhibition of ache with suppression of acetylcholine synthesis into a single compound, cab, enhances the protection against organophosphates. |
1993-03-16 |
2023-08-12 |
Not clear |