| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J H Xuereb, E K Perry, J M Candy, J R Bonham, R H Perry, E Marshal. Parameters of cholinergic neurotransmission in the thalamus in Parkinson's disease and Alzheimer's disease. Journal of the neurological sciences. vol 99. issue 2-3. 1991-05-21. PMID:1964958. |
there were no significant changes in the levels of chat, ache and nicotine binding in the pd and ad groups indicating that involvement of the pedunculopontine tegmental nucleus is likely to be a secondary retrograde phenomenon rather than part of a systematic cholinergic fibre degeneration. |
1991-05-21 |
2023-08-11 |
Not clear |
| R P Gaykema, R van Weeghel, L B Hersh, P G Luite. Prefrontal cortical projections to the cholinergic neurons in the basal forebrain. The Journal of comparative neurology. vol 303. issue 4. 1991-05-14. PMID:2013647. |
the prefrontal cortex (pfc) projections to the basal forebrain cholinergic cell groups in the medial septum (ms), vertical and horizontal limbs of the diagonal band of broca (vdb and hdb), and the magnocellular basal nucleus (mbn) in the rat were investigated by anterograde transport of phaseolus vulgaris leuco-agglutinin (pha-l) combined with acetylcholinesterase (ache) histochemistry or choline acetyltransferase (chat) immunocytochemistry. |
1991-05-14 |
2023-08-11 |
rat |
| L T Larsson, F Sundle. Neuronal markers in Hirschsprung's disease with special reference to neuropeptides. Acta histochemica. Supplementband. vol 38. 1991-04-29. PMID:2080235. |
the nerve fiber hyperplasia together with an increased amount of acetylcholine as well as ache activity in the aganglionic segment suggests a cholinergic hyperinnervation. |
1991-04-29 |
2023-08-11 |
Not clear |
| L T Larsson, F Sundle. Neuronal markers in Hirschsprung's disease with special reference to neuropeptides. Acta histochemica. Supplementband. vol 38. 1991-04-29. PMID:2080235. |
techniques demonstrating the cholinergic and adrenergic hyperinnervation in the aganglionic intestine such as ache staining and staining for adrenergic nerves are also of interest for the diagnosis. |
1991-04-29 |
2023-08-11 |
Not clear |
| L C Streichert, P B Sargen. Differential effects of denervation on acetylcholinesterase activity in parasympathetic and sympathetic ganglia of the frog, Rana pipiens. Journal of neurobiology. vol 21. issue 6. 1991-04-22. PMID:2077105. |
denervation resulted in a significant increase in intracellular ache in cholinergic cardiac ganglia but had no effect on intracellular ache activity in adrenergic lumbar ganglia. |
1991-04-22 |
2023-08-11 |
Not clear |
| V Kraus, A Gombo. [Changes in cholinergic innervation in the human oviduct during pregnancy]. Ceskoslovenska gynekologie. vol 55. issue 10. 1991-03-27. PMID:2285938. |
using a neurohistochemical method for visualization of ache positive nerves according to el badawi and schenk (5), the authors investigated the distribution of the cholinergic innervation in the oviducts of pregnant women. |
1991-03-27 |
2023-08-11 |
human |
| R von Bernhardi, H Ayal, N C Inestros. Carrageenans solubilize asymmetric acetylcholinesterase from nicotinic cholinergic synapses. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 96. issue 1. 1991-03-18. PMID:1980885. |
acetylcholinesterase (ache) catalyzes the hydrolysis of acetylcholine at cholinergic synapses in both vertebrate and invertebrates organisms. |
1991-03-18 |
2023-08-11 |
Not clear |
| P Fossier, G Baux, B Poulain, L Tau. Receptor-mediated presynaptic facilitation of quantal release of acetylcholine induced by pralidoxime in Aplysia. Cellular and molecular neurobiology. vol 10. issue 3. 1991-01-24. PMID:2253262. |
possible interactions of contrathion (pralidoxime sulfomethylate), a reactivator of phosphorylated acetylcholinesterase (ache), with the regulation of cholinergic transmission were investigated on an identified synapse in the buccal ganglion of aplysia californica. |
1991-01-24 |
2023-08-11 |
aplysia |
| U Kumar, A Sellströ. Development of cholinergic markers in the neuroblastoma, N1E-115. Journal of neuroscience research. vol 27. issue 1. 1991-01-24. PMID:2254960. |
it is concluded that the development of the cholinergic marker qnb-binding is intimately associated with that of the "presynaptic" marker cat, whereas the development of ache seems to be unrelated to these cholinergic parameters. |
1991-01-24 |
2023-08-11 |
cat |
| S Laganiere, M Marinko, J Corey, E Wulfert, I Hani. Sector-dependent neurotoxicity of ethylcholine aziridinium (AF64A) in the rat hippocampus. Neuropharmacology. vol 29. issue 10. 1991-01-24. PMID:2255388. |
in vehicle-treated rats, the high affinity cholinergic transport (hacht), choline acetyltransferase (chat) and acetylcholinesterase (ache) activities were distributed according to a gradient of increasing activity, extending from the lateral to the medial surface of the hippocampus. |
1991-01-24 |
2023-08-11 |
rat |
| M Oudega, E Maran. Acetylcholinesterase in the developing rat spinal cord: an enzyme histochemical study. European journal of morphology. vol 28. issue 2-4. 1991-01-10. PMID:2245142. |
this early expression suggested a function of ache in the development of the motor neurons, rather than an active role in cholinergic transmission. |
1991-01-10 |
2023-08-11 |
rat |
| B V Manyam, E Giacobini, J A Collive. Cerebrospinal fluid acetylcholinesterase and choline measurements in Huntington's disease. Journal of neurology. vol 237. issue 5. 1990-12-04. PMID:2146369. |
because of these findings, the cholinergic function in hd was studied by measuring cerebrospinal fluid (csf) choline levels and ache activity during a randomized, double-blind, cross-over, placebo-controlled clinical trial of isoniazid. |
1990-12-04 |
2023-08-11 |
Not clear |
| R F Alderson, A L Alterman, Y A Barde, R M Lindsa. Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture. Neuron. vol 5. issue 3. 1990-10-19. PMID:2169269. |
brain-derived neurotrophic factor (bdnf) was found to promote the survival of e17 rat embryo septal cholinergic neurons in culture, as assessed by a histochemical stain for acetylcholinesterase (ache). |
1990-10-19 |
2023-08-11 |
rat |
| R F Alderson, A L Alterman, Y A Barde, R M Lindsa. Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture. Neuron. vol 5. issue 3. 1990-10-19. PMID:2169269. |
bdnf was also found to increase the levels of cholinergic enzymes; choline acetyltransferase (chat) and ache activities were increased by approximately 2-fold in the presence of 50 ng/ml bdnf. |
1990-10-19 |
2023-08-11 |
rat |
| J K Marqui. Pharmacological significance of acetylcholinesterase inhibition by tetrahydroaminoacridine. Biochemical pharmacology. vol 40. issue 5. 1990-09-27. PMID:2390104. |
tetrahydroaminoacridine (tha; tacrine) is a potent, non-competitive inhibitor of the neuronal enzyme acetylcholinesterase (ache) and, consequently, a potent modulator of central cholinergic function. |
1990-09-27 |
2023-08-11 |
cattle |
| J K Marqui. Pharmacological significance of acetylcholinesterase inhibition by tetrahydroaminoacridine. Biochemical pharmacology. vol 40. issue 5. 1990-09-27. PMID:2390104. |
the kinetic analyses were also designed to determine whether chemical modification of peripheral anionic sites on ache may provide insight into mechanism for selective pharmacological alteration of cholinergic function in the brain. |
1990-09-27 |
2023-08-11 |
cattle |
| K Hozawa, R S Kimur. Cholinergic and noradrenergic nervous systems in the cynomolgus monkey cochlea. Acta oto-laryngologica. vol 110. issue 1-2. 1990-09-20. PMID:1974732. |
the cholinergic and noradrenergic nervous systems in the cochleas of cynomolgus monkeys were examined by histochemical and immunohistochemical demonstration of acetylcholinesterase (ache) and tyrosine hydroxylase (th) and/or dopamine b-hydroxylase (dbh), respectively. |
1990-09-20 |
2023-08-11 |
monkey |
| S Katayama, S Kito, Y Yamamur. Increase of muscarinic receptor following kainic acid lesions of the nucleus basalis magnocellularis in rat brain: an autoradiographic study. Research communications in chemical pathology and pharmacology. vol 68. issue 3. 1990-09-17. PMID:2385763. |
the area with decreased ache activity and increased density in 3h-qnb binding sites corresponded to the innervation of the cholinergic system arising from the nbm. |
1990-09-17 |
2023-08-11 |
rat |
| J C Szerb, A Fin. Is glutamate a co-transmitter in cortical cholinergic terminals? Effects of nucleus basalis lesion and of presynaptic muscarinic agents. Brain research. vol 515. issue 1-2. 1990-08-01. PMID:1972643. |
to obtain additional evidence in support of the co-transmitter role of glutamate in cortical cholinergic terminals proposed by docherty et al., the right nucleus basalis in rats was lesioned with ibotenic acid; resulting changes in cortical acetylcholinesterase (ache) staining, glutamate content, and the release of [3h]acetylcholine ([ 3h]ach) and glutamate from cortical slices from the two sides were compared. |
1990-08-01 |
2023-08-11 |
rat |
| M B Abou-Donia, D M Lapadul. Mechanisms of organophosphorus ester-induced delayed neurotoxicity: type I and type II. Annual review of pharmacology and toxicology. vol 30. 1990-06-26. PMID:2188574. |
most of these compounds are direct or indirect inhibitors of ache, and produce acute cholinergic effects. |
1990-06-26 |
2023-08-11 |
cattle |