| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Raivich, G W Kreutzber. Topography of beta NGF receptor-positive and AChE-reactive neurons in the central nervous system. EXS. vol 57. 1990-03-15. PMID:2558908. |
to learn more about the action of beta ngf in the central nervous system we have mapped the distribution of beta ngf receptors and compared it with that of acetylcholinesterase (ache), a sensitive enzyme marker for cholinergic neurons. |
1990-03-15 |
2023-08-11 |
Not clear |
| T N Robinson, R J De Souza, A J Cross, A R Gree. The mechanism of tetrahydroaminoacridine-evoked release of endogenous 5-hydroxytryptamine and dopamine from rat brain tissue prisms. British journal of pharmacology. vol 98. issue 4. 1990-03-14. PMID:2611486. |
1 tetrahydroaminoacridine (tha) is an acetylcholinesterase (ache) inhibitor which may have a greater therapeutic effect in alzheimer-type dementia (atd) than other cholinergic agents. |
1990-03-14 |
2023-08-11 |
rat |
| L T Robertson, N Roma. Distribution of acetylcholinesterase in the granular layer of the cerebellum of the rhesus monkey (Macaca mulatta). Brain, behavior and evolution. vol 34. issue 6. 1990-03-08. PMID:2611640. |
the high levels of ache activity in the flocculonodular lobe and lobule ix may correspond to cholinergic mossy fiber transmission, but the high levels of ache activity in other cerebellar regions probably involve noncholinergic functions. |
1990-03-08 |
2023-08-11 |
monkey |
| N J Woolf, L L Butche. Cholinergic systems in the rat brain: IV. Descending projections of the pontomesencephalic tegmentum. Brain research bulletin. vol 23. issue 6. 1990-03-08. PMID:2611694. |
descending projections from cholinergic neurons in the pedunculopontine and laterodorsal tegmental nuclei, collectively referred to as the pontomesencephalotegmental (pmt) cholinergic complex, were studied by use of the fluorescent retrograde tracers fluorogold, true blue, or evans blue in combination with choline acetyltransferase (chat) immunohistochemistry of acetylcholinesterase (ache) pharmacohistochemistry. |
1990-03-08 |
2023-08-11 |
rat |
| N J Woolf, L L Butche. Cholinergic systems in the rat brain: IV. Descending projections of the pontomesencephalic tegmentum. Brain research bulletin. vol 23. issue 6. 1990-03-08. PMID:2611694. |
fluorescent tracers used in combination with ache pharmacohistochemistry corroborated these projections and, in addition, provided evidence for cholinergic pontomesencephalic projections to the lateral reticular nucleus and inferior olive. |
1990-03-08 |
2023-08-11 |
rat |
| J A Nielsen, E E Mena, I H Williams, M R Nocerini, D Listo. Correlation of brain levels of 9-amino-1,2,3,4-tetrahydroacridine (THA) with neurochemical and behavioral changes. European journal of pharmacology. vol 173. issue 1. 1990-02-22. PMID:2606156. |
we conclude that brain ache inhibition by tha is sufficient to explain its purported therapeutic activity in alzheimer's disease and that its favorable brain/plasma distribution in vivo may account for its central cholinergic action without inducing the severe peripheral cholinergic effects typically seen with other ache inhibitors. |
1990-02-22 |
2023-08-11 |
mouse |
| C F Hohman. Expression of cholinergic markers in transplants of immature mouse neocortex into adult mouse parietal cortex. Anatomy and embryology. vol 180. issue 6. 1990-02-20. PMID:2610385. |
these results are in accordance with the normal developmental time course of the two different cholinergic markers, since muscarinic receptors appear prenatally in cortex while ache becomes histochemically detectable after birth. |
1990-02-20 |
2023-08-11 |
mouse |
| B Amole, N Sharpless, M Wittner, H B Tanowit. Neurochemical measurements in the brains of mice infected with Trypanosoma brucei brucei (TREU 667). Annals of tropical medicine and parasitology. vol 83. issue 3. 1990-01-29. PMID:2481428. |
to study the possible neurochemical basis of these abnormalities, we measured brain acetylcholine receptor numbers, activities of the cholinergic enzymes, choline acetyltransferase (cat), and acetylcholinesterase (ache), and regional concentrations of the monoamines, dopamine (da), serotonin (5-ht), and norepinephrine (ne), and their acid metabolites, homovanillic acid (hva), 3,4-dihydroxyphenylacetic acid (dopac), and 5-hydroxyindoleacetic acid (5-hiaa) in mice infected with t. b. brucei. |
1990-01-29 |
2023-08-11 |
mouse |
| T Egashira, T Nagai, Y Kimba, R Takano, Y Yamanak. Effects of bifemelane hydrochloride on various cholinergic markers in cortical and subcortical regions of aged rats. Japanese journal of pharmacology. vol 51. issue 2. 1990-01-25. PMID:2593378. |
the effects of bifemelane hydrochloride (bf) upon various cholinergic markers, muscarinic receptors, acetylcholinesterase (ache) and choline acetyltransferase (cat), in the aged rat brain were examined. |
1990-01-25 |
2023-08-11 |
rat |
| H Kobayashi, A Yuyama, K Shioya, K Sat. Effects of carbamate, BPMC, on the central cholinergic functions and behavior of mice. Nihon juigaku zasshi. The Japanese journal of veterinary science. vol 51. issue 4. 1990-01-10. PMID:2585933. |
bpmc may reversibly impair cholinergic functions through effects not only on ache activity but also on hacu and binding of [3h]qnb. |
1990-01-10 |
2023-08-11 |
mouse |
| C Nyquist-Battie, R T Dowell, H Fernande. Acetylcholinesterase molecular forms in muscle and non-muscle cells of rat heart. Journal of molecular and cellular cardiology. vol 21. issue 10. 1990-01-03. PMID:2585521. |
the proportions of globular ache forms plus the high specific activity of choline acetyltransferase in the non-muscle cell fraction suggest that this fraction contains cholinergic nerve fragments. |
1990-01-03 |
2023-08-11 |
rat |
| X C Tang, P De Sarno, K Sugaya, E Giacobin. Effect of huperzine A, a new cholinesterase inhibitor, on the central cholinergic system of the rat. Journal of neuroscience research. vol 24. issue 2. 1989-12-28. PMID:2585551. |
the present study represents the first comprehensive investigation of the effect of huperzine a (hup-a), a new cholinesterase inhibitor (chei) isolated from a lycopodium species, upon acetylcholinesterase (ache) activity, acetylcholine (ach) levels and release, and cholinergic receptors in rat brain following acute i.m. |
1989-12-28 |
2023-08-11 |
mouse |
| A C Santucci, P D Kanof, V Haroutunia. Infusion of NMDA into the nucleus basalis of Meynert, frontal cortex or lateral ventricle in rats: effect on memory and cholinergic brain neurochemistry. Pharmacology, biochemistry, and behavior. vol 33. issue 2. 1989-12-19. PMID:2682674. |
specifically, it was of interest to evaluate the effects of n-methyl-d-aspartic acid-induced lesions of discrete frontal cortical loci on passive avoidance memory and on cortical cholinergic neurochemical markers (choline acetyltransferase--cat and acetylcholinesterase--ache). |
1989-12-19 |
2023-08-11 |
human |
| V L Dawson, F H Gage, M A Hunt, J K Wamsle. Normalization of subtype-specific muscarinic receptor binding in the denervated hippocampus by septodiagonal band grafts. Experimental neurology. vol 106. issue 2. 1989-12-12. PMID:2806454. |
lesion of the fimbria-fornix resulted in a reduction of cholinergic input to the hippocampal formation as indicated by the loss of acetylcholinesterase (ache)-positive staining in all ipsilateral hippocampal laminae and a loss of [3h]hemicholinium-3 binding to cholinergic terminals in the strata oriens (82% reduction) and radiatum (77% reduction) of areas ca2 and ca3 and in the molecular layer of the dentate gyrus (83% reduction). |
1989-12-12 |
2023-08-11 |
rat |
| A J Gower, D Rousseau, P Jamsin, J Gobert, I Hanin, E Wülfer. Behavioural and histological effects of low concentrations of intraventricular AF64A. European journal of pharmacology. vol 166. issue 2. 1989-11-06. PMID:2792193. |
biochemical efficacy of the lesions in terms of cholinergic changes was confirmed by analysis of acetylcholinesterase (ache) levels showing decreases in the hippocampus and the cortex; no studies were carried out with respect to other neurotransmitters. |
1989-11-06 |
2023-08-11 |
rat |
| J A Vega Alvarez, A Martínez Tellería, C Coalla, M E Bengoechea, A Pérez Casa. [Cholinergic innervation of the prostate in the white rat (Rattus norvegicus)]. Archivos espanoles de urologia. vol 42. issue 4. 1989-10-17. PMID:2782953. |
we studied the cholinergic innervation of the prostate in male albino rats using a technic for demonstrating acetylcholinesterase (ache) activity. |
1989-10-17 |
2023-08-11 |
rat |
| G Yang, T J Millar, I G Morga. Co-lamination of cholinergic amacrine cell and displaced ganglion cell dendrites in the chicken retina. Neuroscience letters. vol 103. issue 2. 1989-10-12. PMID:2475831. |
counter-staining for acetylcholinesterase (ache) activity showed that the dendrites of the displaced ganglion cells and the type i cholinergic amacrine cells co-laminated in the outer part of the inner plexiform layer. |
1989-10-12 |
2023-08-11 |
chicken |
| J Clos, S Ghandour, R Eberhart, G Vincendon, G Gombo. The cholinergic system in developing cerebellum: comparative study of normal, hypothyroid and underfed rats. Developmental neuroscience. vol 11. issue 3. 1989-10-06. PMID:2766963. |
when compared with structural findings in the literature, the results provide the following information on the normal and abnormal developing cholinergic system, related or not to cerebellar neurotransmission (1) ache activity, unlike chat, can be considered as a good marker of the developing cholinergic archicerebellum. |
1989-10-06 |
2023-08-11 |
rat |
| M Schinstine, C J Cornbrook. Effect of nerve growth factor on the elongation of neurites from axotomized rat embryonic septal-basal forebrain neurons: an in vitro analysis. Journal of neuroscience research. vol 23. issue 4. 1989-10-03. PMID:2549266. |
acetylcholinesterase (ache) histochemistry was used to assess the effects of ngf on cholinergic neurites. |
1989-10-03 |
2023-08-11 |
rat |
| S Kreissl, G Bicke. Histochemistry of acetylcholinesterase and immunocytochemistry of an acetylcholine receptor-like antigen in the brain of the honeybee. The Journal of comparative neurology. vol 286. issue 1. 1989-10-03. PMID:2768558. |
a histochemical staining method for acetylcholinesterase (ache) and an antiserum raised against nicotinic acetylcholine receptors (achr) of locust nervous tissue were applied in order to reveal certain candidates of cholinergic pathways in the brain of the honeybee. |
1989-10-03 |
2023-08-11 |
bee |