| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B E Jones, H H Webste. Neurotoxic lesions of the dorsolateral pontomesencephalic tegmentum-cholinergic cell area in the cat. I. Effects upon the cholinergic innervation of the brain. Brain research. vol 451. issue 1-2. 1989-07-31. PMID:3251579. |
the effects of these lesions upon the cholinergic innervation of the brain were investigated by comparison of brains with and without lesions which were processed for acetylcholinesterase (ache) silver, copper thiocholine histochemistry and chat radio-immunohistochemistry. |
1989-07-31 |
2023-08-11 |
cat |
| B E Jones, H H Webste. Neurotoxic lesions of the dorsolateral pontomesencephalic tegmentum-cholinergic cell area in the cat. I. Effects upon the cholinergic innervation of the brain. Brain research. vol 451. issue 1-2. 1989-07-31. PMID:3251579. |
all of these nuclei receive a rich cholinergic innervation evident in both ache histochemistry and chat immunohistochemistry. |
1989-07-31 |
2023-08-11 |
cat |
| H M Sobkowicz, M R Emmerlin. Development of acetylcholinesterase-positive neuronal pathways in the cochlea of the mouse. Journal of neurocytology. vol 18. issue 2. 1989-07-17. PMID:2732759. |
development of the cholinergic enzymes, choline acetyltransferase (chat) and ache, and of the ache-positive innervation in the cochlea was studied biochemically and morphologically in the postnatal mouse up to 26 days. |
1989-07-17 |
2023-08-11 |
mouse |
| R N Dimova, K G Usunof. Cortical projection of giant neostriatal neurons in the cat. Light and electron microscopic horseradish peroxidase study. Brain research bulletin. vol 22. issue 3. 1989-06-15. PMID:2713722. |
the simultaneous demonstration of retrogradely transported hrp and acetylcholinesterase (ache) suggest that the large neurons are presumably cholinergic. |
1989-06-15 |
2023-08-11 |
cat |
| N Tønder, T Sørensen, J Zimmer, M B Jørgensen, F F Johansen, N H Dieme. Neural grafting to ischemic lesions of the adult rat hippocampus. Experimental brain research. vol 74. issue 3. 1989-06-01. PMID:2707327. |
judged by the ache staining the grafts were innervated by cholinergic host septohippocampal fibers. |
1989-06-01 |
2023-08-11 |
rat |
| D Casper, P Davie. Stimulation of choline acetyltransferase activity by retinoic acid and sodium butyrate in a cultured human neuroblastoma. Brain research. vol 478. issue 1. 1989-04-27. PMID:2924123. |
choline acetyltransferase (acetyl-coa:choline o-acetyltransferase, ec 2.3.1.6, abbreviated chat), the biosynthetic enzyme for acetylcholine and acetylcholinesterase (ec 3.1.1.7, abbreviated ache) are expressed in a human cholinergic neuroblastoma cell line, mc-ixc. |
1989-04-27 |
2023-08-11 |
human |
| E C Hirsch, A M Graybiel, L B Hersh, C Duyckaerts, Y Agi. Striosomes and extrastriosomal matrix contain different amounts of immunoreactive choline acetyltransferase in the human striatum. Neuroscience letters. vol 96. issue 2. 1989-04-24. PMID:2522606. |
the cholinergic neuropil was not uniformly distributed in the striatum, and especially in the caudate nucleus chat-poor zones corresponding to acetylcholinesterase (ache)-poor striosomes were identified. |
1989-04-24 |
2023-08-11 |
human |
| M Eriksdotter-Nilsson, S Skirboll, T Ebendal, L Hersh, J Grassi, J Massoulié, L Olso. NGF treatment promotes development of basal forebrain tissue grafts in the anterior chamber of the eye. Experimental brain research. vol 74. issue 1. 1989-04-24. PMID:2924843. |
following pretreatment with diisopropylfluorophosphate (dfp), the cholinergic neurons in the grafts were analyzed using three morphological markers: antibodies to cholineacetyltransferase (chat), antibodies to acetylcholinesterase (ache ab) and acetylcholinesterase histochemistry (ache). |
1989-04-24 |
2023-08-11 |
rat |
| S Kish, H Karlinsky, L Becker, J Gilbert, M Rebbetoy, L J Chang, L DiStefano, O Hornykiewic. Down's syndrome individuals begin life with normal levels of brain cholinergic markers. Journal of neurochemistry. vol 52. issue 4. 1989-04-21. PMID:2522539. |
we measured the activities of the cholinergic marker enzymes choline acetyltransferase (chat) and acetylcholinesterase (ache) in autopsied brains of seven infants (age range 3 months to 1 year) with down's syndrome (ds), a disorder in which virtually all individuals will develop by middle age the neuropathological changes of alzheimer's disease accompanied by a marked brain cholinergic reduction. |
1989-04-21 |
2023-08-11 |
Not clear |
| S Kish, H Karlinsky, L Becker, J Gilbert, M Rebbetoy, L J Chang, L DiStefano, O Hornykiewic. Down's syndrome individuals begin life with normal levels of brain cholinergic markers. Journal of neurochemistry. vol 52. issue 4. 1989-04-21. PMID:2522539. |
when compared with age-matched controls cholinergic enzyme activity was normal in all brain regions of the individuals with infant ds with the exception of above-normal activity in the putamen (chat) and the occipital cortex (ache). |
1989-04-21 |
2023-08-11 |
Not clear |
| D W Schwarz, I E Schwarz, K H. Transmitter neurochemistry of the efferent neuron system innervating the labyrinth. The Journal of otolaryngology. vol 18. issue 1. 1989-04-18. PMID:2564051. |
medial cochlear efferents, terminating under outer hair cells, may also be cholinergic since they stain intensely for acetylcholine esterase (ache) after pre-treatment with the ache inhibitor diisopropylfluorophosphate (dfp). |
1989-04-18 |
2023-08-11 |
rat |
| S Manolov, M Davidof. [Acetylcholinesterase activity, choline acetyltransferase and GABA immunoreactivity in the ventral horn of the spinal cord of rats during chromatolysis]. Revue neurologique. vol 145. issue 1. 1989-04-11. PMID:2646682. |
these results suggest that during chromatolysis: 1. the production of acetylcholine and gaba decreases; 2. the gaba which coexists within some cholinergic motoneurons may be expressed by these cells and 3. the ache activity may also in the future be used as a marker of the cholinergic system of the anterior horn cells of the spinal cord. |
1989-04-11 |
2023-08-11 |
rat |
| F H Gage, S N Blaker, G E Davis, E Engvall, S Varon, M Manthorp. Human amnion membrane matrix as a substratum for axonal regeneration in the central nervous system. Experimental brain research. vol 72. issue 2. 1989-04-06. PMID:3224648. |
by double-labelling for the basement membrane side of the hamm (using anti-human laminin antibodies) and for cholinergic fibers (using ache histochemistry) in the same sections, it was possible to see fibers clearly growing on the laminin-positive side of the hamm but little or no growth on the opposing laminin-negative stromal side. |
1989-04-06 |
2023-08-11 |
human |
| J Hartikka, F Heft. Comparison of nerve growth factor's effects on development of septum, striatum, and nucleus basalis cholinergic neurons in vitro. Journal of neuroscience research. vol 21. issue 2-4. 1989-03-08. PMID:3216428. |
we now report that, first, cholinergic neurons of striatum and nucleus basalis develop a more extensive fiber network and contain more acetylcholinesterase (ache) per neuron than do cholinergic neurons of septum. |
1989-03-08 |
2023-08-11 |
rat |
| J Hartikka, F Heft. Comparison of nerve growth factor's effects on development of septum, striatum, and nucleus basalis cholinergic neurons in vitro. Journal of neuroscience research. vol 21. issue 2-4. 1989-03-08. PMID:3216428. |
fourth, ngf treatment increases ache activity in septal but not in nucleus basalis or striatal cultures, suggesting that ache activity reflects the extent of the fiber network of cholinergic neurons of all areas. |
1989-03-08 |
2023-08-11 |
rat |
| K Hisanaga, H Tsukui, N Takei, H Hatanak. Transplantation of fetal and early postnatal rat septal cholinergic neurons cultured in serum-free and serum-containing medium with nerve growth factor. Brain research. vol 475. issue 2. 1989-02-28. PMID:3214739. |
the cholinergic septal neurons, which were visualized by acetylcholinesterase (ache) histochemistry, always survived in transplantation to the adult brains from nearly pure neuronal cultures. |
1989-02-28 |
2023-08-11 |
rat |
| B E Lams, O Isacson, M V Sofronie. Loss of transmitter-associated enzyme staining following axotomy does not indicate death of brainstem cholinergic neurons. Brain research. vol 475. issue 2. 1989-02-28. PMID:3214743. |
to assess the validity of using loss of transmitter-associated enzyme staining to document the death of injured cholinergic neurons, vagal and hypoglossal cholinergic neurons were quantitatively identified at 7 and 28 days following unilateral axotomy using staining procedures for choline acetyltransferase (chat) or acetylcholinesterase (ache), using nissl stains, and using the retrogradely transported dye, true blue, as an intracellular marker. |
1989-02-28 |
2023-08-11 |
Not clear |
| R C Green, M M Mesula. Acetylcholinesterase fiber staining in the human hippocampus and parahippocampal gyrus. The Journal of comparative neurology. vol 273. issue 4. 1989-02-21. PMID:3209735. |
the ache fiber distribution within the human hippocampus and parahippocampal gyrus was studied in order to provide normative data for the examination of cholinergic fiberarchitecture in human pathology and to clarify the cytoarchitectonic organization of these structures. |
1989-02-21 |
2023-08-11 |
human |
| R J Clinton, F F Ebne. Time course of neocortical graft innervation by AChE-positive fibers. The Journal of comparative neurology. vol 277. issue 4. 1989-02-10. PMID:3209746. |
in the present paper we compare the time course of ache-positive fiber innervation in the normal mouse cortex with that seen in neocortical grafts by using ache histochemistry as a marker for presumed cholinergic fibers. |
1989-02-10 |
2023-08-11 |
mouse |
| K K Hreib, D L Rosene, M B Mos. Basal forebrain efferents to the medial dorsal thalamic nucleus in the rhesus monkey. The Journal of comparative neurology. vol 277. issue 3. 1989-01-24. PMID:2461974. |
in order to determine the extent of the cholinergic input to mdmc from the bf, one of the hrp cases was processed for the simultaneous visualization of hrp, and acetylcholinesterase (ache), the hydrolytic enzyme for acetylcholine, and a second case was processed for simultaneous visualization of hrp, and choline acetyltransferase (chat), the synthetic enzyme for acetylcholine. |
1989-01-24 |
2023-08-11 |
monkey |