| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P J Riekkinen, H Soininen, J Sirviö, K Reinikainen, E L Helkala, L Paljärv. Dementia without cholinergic deficit. Gerontology. vol 33. issue 3-4. 1987-11-20. PMID:3653707. |
we examined the role of cholinergic system in multi-infarct dementia (mid) by measuring acetylcholinesterase (ache) activities in cerebrospinal fluid (csf) of clinically diagnosed mid patients, alzheimer's disease (ad) patients and controls. |
1987-11-20 |
2023-08-11 |
Not clear |
| A K Singh, L R Drewe. Neurotoxic effects of low-level chronic acephate exposure in rats. Environmental research. vol 43. issue 2. 1987-09-18. PMID:3608937. |
these observations suggest that chronic exposure to acephate altered the activity of the noncholinergic system without altering the cholinergic activity, and that low-level chronic exposure to organophosphorous compounds cannot be predicted by measuring the che or ache enzyme activities. |
1987-09-18 |
2023-08-11 |
rat |
| S Herscovich, D Gersho. Effects of aging and physical training on the neuromuscular junction of the mouse. Gerontology. vol 33. issue 1. 1987-08-12. PMID:3596265. |
synaptic function was found to be considerably reduced in old age, as revealed by the activity of the cholinergic enzymes choline acetyltransferase (cat) and acetylcholinesterase (ache). |
1987-08-12 |
2023-08-11 |
mouse |
| F Dajas, B Bolioli, M E Castello, R Silveir. Rat striatal acetylcholinesterase inhibition by fasciculin (a polypeptide from green mamba snake venom). Neuroscience letters. vol 77. issue 1. 1987-08-10. PMID:3601220. |
it is postulated that, due to this potent, localized and long-lasting central nervous system ache inhibition, fas could become a useful tool for the study of central cholinergic pathways. |
1987-08-10 |
2023-08-11 |
rat |
| E B Ezerman, L F Krome. Transplants of cholinergic septal explants reinnervate adult rodent hippocampus. Brain research bulletin. vol 18. issue 3. 1987-07-16. PMID:3580909. |
analysis of fiber ingrowth by acetylcholinesterase (ache) histochemistry at various timepoints post-transplantation shows little difference in the developmental time course or extent of cholinergic axon ingrowth into the host hippocampus between the suspension transplants and the explant transplants. |
1987-07-16 |
2023-08-11 |
rat |
| J E Springer, M W Tayrien, R Lo. Regional analysis of age-related changes in the cholinergic system of the hippocampal formation and basal forebrain of the rat. Brain research. vol 407. issue 1. 1987-07-14. PMID:3580852. |
in an attempt to clarify conflicting reports of age-related changes in cholinergic systems of the rat hippocampal formation and basal forebrain, we compared aged (40 months) and adult (12 months) male rats using quantitative, regional receptor autoradiography in addition to radiolabelled assays of choline acetyltransferase (chat) and acetylcholinesterase (ache). |
1987-07-14 |
2023-08-11 |
rat |
| M Ruberg, A Villageois, A M Bonnet, B Pillon, F Rieger, Y Agi. Acetylcholinesterase and butyrylcholinesterase activity in the cerebrospinal fluid of patients with neurodegenerative diseases involving cholinergic systems. Journal of neurology, neurosurgery, and psychiatry. vol 50. issue 5. 1987-07-07. PMID:2953866. |
acetylcholinesterase (ache) and butyrylcholinesterase (bche) were assayed in the cerebrospinal fluid (csf) of subjects with neurodegenerative diseases (dementing and non-dementing, with and without known cholinergic lesions), to determine whether csf ache is a valid marker of central cholinergic activity. |
1987-07-07 |
2023-08-11 |
human |
| M Ruberg, A Villageois, A M Bonnet, B Pillon, F Rieger, Y Agi. Acetylcholinesterase and butyrylcholinesterase activity in the cerebrospinal fluid of patients with neurodegenerative diseases involving cholinergic systems. Journal of neurology, neurosurgery, and psychiatry. vol 50. issue 5. 1987-07-07. PMID:2953866. |
ache decreased in huntington's chorea (degeneration of striatal cholinergic interneurons) but also in multiple sclerosis (not known to affect cholinergic systems). |
1987-07-07 |
2023-08-11 |
human |
| P Aas, T A Veiteberg, F Fonnu. Acute and sub-acute inhalation of an organophosphate induce alteration of cholinergic muscarinic receptors. Biochemical pharmacology. vol 36. issue 8. 1987-07-01. PMID:3593413. |
in spite of the extensive inhibition of ache and reduction in the contraction following cholinergic stimulation, there was no alteration of the binding capacity (bmax) or the equilibrium dissociation constant (kd) to [3h]-quinuclidinyl benzilate ([3h]-qnb) in the rat bronchi following such an acute exposure. |
1987-07-01 |
2023-08-11 |
rat |
| P D Walker, G I Chovanes, J P McAlliste. Identification of acetylcholinesterase-reactive neurons and neuropil in neostriatal transplants. The Journal of comparative neurology. vol 259. issue 1. 1987-06-30. PMID:3584552. |
one type resembled the large intensely reactive ache neuron that is thought to be a cholinergic interneuron of the normal neostriatum. |
1987-06-30 |
2023-08-11 |
rat |
| B H Gähwiler, A Enz, F Heft. Nerve growth factor promotes development of the rat septo-hippocampal cholinergic projection in vitro. Neuroscience letters. vol 75. issue 1. 1987-05-28. PMID:3574769. |
application of 100 ng/ml ngf greatly increased the number of acetylcholinesterase (ache)-positive fibers which invaded the hippocampal slices, an effect which was accompanied by a more than 6-fold elevation of the two major cholinergic enzymes, choline acetyltransferase and ache. |
1987-05-28 |
2023-08-11 |
rat |
| P Ekströ. Distribution of choline acetyltransferase-immunoreactive neurons in the brain of a cyprinid teleost (Phoxinus phoxinus L.). The Journal of comparative neurology. vol 256. issue 4. 1987-05-21. PMID:3549797. |
the distribution of putative cholinergic neurons in the brain of a cyprinid teleost was investigated by immunocytochemistry, with well-characterized polyclonal antibodies to porcine choline acetyltransferase (chat), correlated with acetylcholinesterase (ache) histochemistry. |
1987-05-21 |
2023-08-11 |
Not clear |
| T Iijima, T Kondo, K Hasegaw. Autonomic innervation of the arteriovenous anastomoses in the dog tongue. A histochemical and ultrastructural study. Cell and tissue research. vol 247. issue 1. 1987-05-04. PMID:3829114. |
all axons stained heavily with reaction products for ache activity, suggesting their cholinergic nature. |
1987-05-04 |
2023-08-11 |
dog |
| E Brandan, N C Inestros. Co-solubilization of asymmetric acetylcholinesterase and dermatan sulfate proteoglycan from the extracellular matrix of rat skeletal muscles. FEBS letters. vol 213. issue 1. 1987-04-27. PMID:3556575. |
we have previously communicated that heparin released asymmetric acetylcholinesterase (ache) from cholinergic synapses. |
1987-04-27 |
2023-08-11 |
rat |
| T J Millar, I Ishimoto, M Boelen, M L Epstein, C D Johnson, I G Morga. The toxic effects of ethylcholine mustard aziridinium ion on cholinergic cells in the chicken retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 7. issue 2. 1987-04-01. PMID:2880936. |
this result corresponds to the morphological finding that 2 populations of cholinergic cells were destroyed and that the ache activity associated with their terminal arbors was lost. |
1987-04-01 |
2023-08-11 |
cat |
| T Kitazawa, H Furuhashi, K Umezawa, M Morioka, K Temma, H Kond. Is there functional cholinergic innervation in the frog duodenum (Rana catesbeiana)? Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 85. issue 2. 1987-03-19. PMID:2879686. |
to determine if functional cholinergic innervation occurs in the frog duodenum or not, the effects of exogenous acetylcholine and electrical transmural stimulation, the contractile activity of an acid extract from the frog duodenum, and the distribution of acetylcholinesterase (ache) activity in the wall of the frog duodenum were investigated. |
1987-03-19 |
2023-08-11 |
rat |
| P M Salvaterra, N Bournias-Vardiabasis, T Nair, G Hou, C Lie. In vitro neuronal differentiation of Drosophila embryo cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 7. issue 1. 1987-03-18. PMID:3100730. |
the normal in vitro expression pattern for chat and ache can be altered by adding various cholinergic drugs to the culture medium during cell differentiation. |
1987-03-18 |
2023-08-11 |
drosophila_melanogaster |
| S R Whittemore, L Lärkfors, T Ebendal, V R Holets, A Ericsson, H Persso. Increased beta-nerve growth factor messenger RNA and protein levels in neonatal rat hippocampus following specific cholinergic lesions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 7. issue 1. 1987-03-18. PMID:3806196. |
ten days after transection, hippocampal cholinergic innervation, as assessed by ache histochemistry and cat immunohistochemistry, was decreased, and both hippocampal ngf mrna and protein were elevated about 50%. |
1987-03-18 |
2023-08-11 |
rat |
| L L Vacca-Galloway, C C Steinberge. Substance P neurons sprout in the cervical spinal cord of the wobbler mouse: a model for motoneuron disease. Journal of neuroscience research. vol 16. issue 4. 1987-02-19. PMID:2432278. |
ache is used as a marker for cholinergic neurons and is known to hydrolyze the neuropeptide modulator substance p (sp). |
1987-02-19 |
2023-08-11 |
mouse |
| L L Vacca-Galloway, C C Steinberge. Substance P neurons sprout in the cervical spinal cord of the wobbler mouse: a model for motoneuron disease. Journal of neuroscience research. vol 16. issue 4. 1987-02-19. PMID:2432278. |
presumably, the continual decrease in ache staining represents the degeneration of cholinergic perikarya and neuronal processes in the ventral horn as the motoneuron disease proceeds. |
1987-02-19 |
2023-08-11 |
mouse |